| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||||
| Captopril | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -5.72 | -5.89 | -5.78 | 26.36% | CHEMBL191460 |
| Fosinopril | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.40 | -9.58 | -8.89 | 32.71% | CHEMBL3126382 |
| Lisinopril | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -7.98 | -8.27 | -8.25 | 45.69% | CHEMBL191460 |
| Ramipril | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.38 | -9.03 | -9.25 | 45.24% | CHEMBL191460 |
| Moexipril | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.89 | -8.99 | -8.52 | 44.33% | CHEMBL467094 |
| Captopril | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -5.95 | -5.89 | N/A | 33.33% | CHEMBL506654 |
| Fosinopril | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -10.38 | -8.60 | N/A | 36.41% | CHEMBL3676863 |
| Lisinopril | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.83 | -8.53 | N/A | 56.14% | CHEMBL1278113 |
| Ramipril | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.36 | -9.29 | N/A | 52.38% | CHEMBL1278113 |
| Moexipril | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.81 | -9.43 | N/A | 58.75% | CHEMBL2397878 |
| Captopril | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -5.43 | -5.81 | -5.69 | 35.29% | CHEMBL3908870 |
| Fosinopril | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.81 | -8.66 | -8.76 | 31.87% | CHEMBL1255837 |
| Lisinopril | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -7.50 | -8.12 | -8.37 | 50.00% | CHEMBL209155 |
| Ramipril | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -9.07 | -8.86 | -8.63 | 47.03% | CHEMBL1732 |
| Moexipril | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.81 | -9.06 | -9.01 | 58.75% | CHEMBL2397878 |
| Captopril | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -5.93 | -5.87 | N/A | 35.29% | CHEMBL3908870 |
| Fosinopril | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -9.13 | -9.67 | N/A | 32.04% | CHEMBL1276859 |
| Lisinopril | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -7.89 | -8.24 | N/A | 58.25% | CHEMBL1092029 |
| Ramipril | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.84 | -8.56 | N/A | 52.38% | CHEMBL1278113 |
| Moexipril | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -9.20 | -9.39 | N/A | 59.75% | CHEMBL2397902 |
| Captopril | AA1R_HUMAN | adenosine A1 receptor | -5.22 | -5.15 | -5.59 | 31.72% | CHEMBL3350613 |
| Fosinopril | AA1R_HUMAN | adenosine A1 receptor | -8.48 | -8.97 | -6.94 | 35.81% | CHEMBL3350613 |
| Lisinopril | AA1R_HUMAN | adenosine A1 receptor | -7.62 | -7.85 | -7.91 | 52.41% | CHEMBL3350613 |
| Ramipril | AA1R_HUMAN | adenosine A1 receptor | -7.99 | -9.18 | -6.83 | 58.78% | CHEMBL3350613 |
| Moexipril | AA1R_HUMAN | adenosine A1 receptor | -8.11 | -9.03 | -6.20 | 45.36% | CHEMBL3350613 |
| Captopril | AA2AR_HUMAN | adenosine A2a receptor | -5.14 | -5.17 | -5.76 | 31.72% | CHEMBL3350613 |
| Fosinopril | AA2AR_HUMAN | adenosine A2a receptor | -8.41 | -8.88 | -8.58 | 35.81% | CHEMBL3350613 |
| Lisinopril | AA2AR_HUMAN | adenosine A2a receptor | -7.29 | -7.59 | -8.13 | 52.41% | CHEMBL3350613 |
| Ramipril | AA2AR_HUMAN | adenosine A2a receptor | -7.91 | -7.86 | -8.98 | 58.78% | CHEMBL3350613 |
| Moexipril | AA2AR_HUMAN | adenosine A2a receptor | -8.16 | -8.79 | -7.99 | 46.19% | CHEMBL554840 |
| Captopril | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -6.59 | -6.11 | -6.26 | 49.44% | CHEMBL4078305 |
| Fosinopril | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -9.95 | -9.72 | -6.67 | 35.48% | CHEMBL1080631 |
| Lisinopril | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -8.88 | -9.06 | -9.18 | 52.34% | CHEMBL4078305 |
| Ramipril | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -10.09 | -8.91 | -8.51 | 56.00% | CHEMBL1080631 |
| Moexipril | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -9.99 | -9.11 | -7.91 | 54.60% | CHEMBL3262665 |
| Captopril | ACE_HUMAN | angiotensin I converting enzyme | -5.38 | -5.55 | -5.15 | 100.00% | CHEMBL1560 |
| Fosinopril | ACE_HUMAN | angiotensin I converting enzyme | -8.83 | -8.96 | -3.17 | 100.00% | CHEMBL3039598 |
| Lisinopril | ACE_HUMAN | angiotensin I converting enzyme | -6.97 | -7.96 | -7.24 | 100.00% | CHEMBL1237 |
| Ramipril | ACE_HUMAN | angiotensin I converting enzyme | -7.80 | -8.69 | -7.29 | 100.00% | CHEMBL1168 |
| Moexipril | ACE_HUMAN | angiotensin I converting enzyme | -8.60 | -8.25 | -7.35 | 100.00% | CHEMBL1165 |
| Captopril | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -4.65 | N/A | N/A | 33.33% | CHEMBL386114 |
| Fosinopril | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -6.61 | N/A | N/A | 29.88% | CHEMBL386114 |
| Lisinopril | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -6.42 | N/A | N/A | 44.91% | CHEMBL386114 |
| Ramipril | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -6.10 | N/A | N/A | 40.66% | CHEMBL386114 |
| Moexipril | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -7.40 | N/A | N/A | 37.10% | CHEMBL386114 |
| Captopril | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -4.69 | -6.72 | -6.01 | N/A | N/A |
| Fosinopril | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -3.07 | -3.81 | -2.95 | N/A | N/A |
| Lisinopril | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -7.54 | -8.04 | -7.93 | N/A | N/A |
| Ramipril | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -7.31 | -7.16 | -7.05 | N/A | N/A |
| Moexipril | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -3.74 | -6.43 | -5.95 | N/A | N/A |
| Captopril | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -6.68 | -6.13 | N/A | 41.33% | CHEMBL183331 |
| Fosinopril | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.58 | 4.46 | N/A | 36.84% | CHEMBL69648 |
| Lisinopril | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.29 | -4.25 | N/A | 70.09% | CHEMBL212141 |
| Ramipril | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.69 | -2.64 | N/A | 62.90% | CHEMBL214898 |
| Moexipril | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -6.57 | 10.28 | N/A | 49.11% | CHEMBL148450 |
| Captopril | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -6.35 | -5.63 | N/A | 44.44% | CHEMBL479224 |
| Fosinopril | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.00 | -7.12 | N/A | 35.71% | CHEMBL24369 |
| Lisinopril | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.63 | -7.76 | N/A | 73.53% | CHEMBL211976 |
| Ramipril | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.12 | -6.89 | N/A | 63.25% | CHEMBL211976 |
| Moexipril | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.94 | -6.74 | N/A | 48.28% | CHEMBL240022 |
| Captopril | ADRB2_HUMAN | adrenoceptor beta 2 | -5.73 | -5.85 | -5.59 | 34.62% | CHEMBL1085010 |
| Fosinopril | ADRB2_HUMAN | adrenoceptor beta 2 | -8.49 | -8.86 | -9.47 | 34.78% | CHEMBL3126384 |
| Lisinopril | ADRB2_HUMAN | adrenoceptor beta 2 | -7.58 | -8.85 | -8.29 | 47.57% | CHEMBL1332942 |
| Ramipril | ADRB2_HUMAN | adrenoceptor beta 2 | -7.56 | -7.92 | -9.63 | 48.10% | CHEMBL1835860 |
| Moexipril | ADRB2_HUMAN | adrenoceptor beta 2 | -7.64 | -8.19 | -8.90 | 52.54% | CHEMBL1814274 |
| Captopril | AGTR2_HUMAN | angiotensin II receptor type 2 | -5.01 | -5.12 | -5.08 | 36.89% | CHEMBL3350599 |
| Fosinopril | AGTR2_HUMAN | angiotensin II receptor type 2 | -9.85 | -9.85 | -9.27 | 32.02% | CHEMBL3350599 |
| Lisinopril | AGTR2_HUMAN | angiotensin II receptor type 2 | -7.82 | -7.44 | -6.92 | 61.48% | CHEMBL3350599 |
| Ramipril | AGTR2_HUMAN | angiotensin II receptor type 2 | -8.57 | -8.97 | -8.50 | 54.01% | CHEMBL3350599 |
| Moexipril | AGTR2_HUMAN | angiotensin II receptor type 2 | -9.40 | -9.15 | -8.65 | 69.49% | CHEMBL423236 |
| Captopril | ALDR_HUMAN | aldo-keto reductase family 1 member B | -6.64 | -6.41 | -5.96 | 21.70% | CHEMBL436 |
| Fosinopril | ALDR_HUMAN | aldo-keto reductase family 1 member B | -8.61 | -10.07 | -8.05 | 26.59% | CHEMBL84446 |
| Lisinopril | ALDR_HUMAN | aldo-keto reductase family 1 member B | -7.80 | -7.23 | -7.64 | 33.09% | CHEMBL71701 |
| Ramipril | ALDR_HUMAN | aldo-keto reductase family 1 member B | -8.82 | -7.68 | -7.77 | 33.78% | CHEMBL71562 |
| Moexipril | ALDR_HUMAN | aldo-keto reductase family 1 member B | -9.02 | -8.39 | -9.54 | 43.52% | CHEMBL10350 |
| Captopril | AMPN_HUMAN | alanyl aminopeptidase, membrane | -5.74 | -5.61 | -5.54 | 50.59% | CHEMBL28650 |
| Fosinopril | AMPN_HUMAN | alanyl aminopeptidase, membrane | -8.24 | -8.25 | -7.93 | 45.90% | CHEMBL3804856 |
| Lisinopril | AMPN_HUMAN | alanyl aminopeptidase, membrane | -7.59 | -8.14 | -7.35 | 79.59% | CHEMBL1941150 |
| Ramipril | AMPN_HUMAN | alanyl aminopeptidase, membrane | -8.58 | -8.86 | -7.84 | 68.14% | CHEMBL1941150 |
| Moexipril | AMPN_HUMAN | alanyl aminopeptidase, membrane | -8.36 | -8.60 | -8.14 | 71.15% | CHEMBL1077590 |
| Captopril | AOFA_HUMAN | monoamine oxidase A | -6.27 | -6.11 | -6.44 | 24.47% | CHEMBL3415788 |
| Fosinopril | AOFA_HUMAN | monoamine oxidase A | -9.60 | -9.31 | -6.78 | 26.07% | CHEMBL4073457 |
| Lisinopril | AOFA_HUMAN | monoamine oxidase A | -8.32 | -8.86 | -8.51 | 43.33% | CHEMBL3330339 |
| Ramipril | AOFA_HUMAN | monoamine oxidase A | -9.72 | -9.23 | -8.42 | 38.41% | CHEMBL4073457 |
| Moexipril | AOFA_HUMAN | monoamine oxidase A | -10.65 | -10.17 | -9.05 | 42.07% | CHEMBL1813520 |
| Captopril | AOFB_HUMAN | monoamine oxidase B | -6.67 | -6.59 | -6.60 | 24.47% | CHEMBL3415788 |
| Fosinopril | AOFB_HUMAN | monoamine oxidase B | -9.18 | -7.74 | -8.07 | 27.83% | CHEMBL4067432 |
| Lisinopril | AOFB_HUMAN | monoamine oxidase B | -9.00 | -8.11 | -8.86 | 43.33% | CHEMBL3330339 |
| Ramipril | AOFB_HUMAN | monoamine oxidase B | -8.96 | -8.52 | -8.47 | 37.50% | CHEMBL3330339 |
| Moexipril | AOFB_HUMAN | monoamine oxidase B | -10.01 | -10.60 | -9.56 | 42.07% | CHEMBL1813520 |
| Captopril | BACE1_HUMAN | beta-secretase 1 | -4.95 | -5.04 | -5.59 | 60.27% | CHEMBL461602 |
| Fosinopril | BACE1_HUMAN | beta-secretase 1 | -7.23 | -7.63 | -7.79 | 41.41% | CHEMBL556143 |
| Lisinopril | BACE1_HUMAN | beta-secretase 1 | -6.67 | -6.83 | -7.31 | 86.02% | CHEMBL1917900 |
| Ramipril | BACE1_HUMAN | beta-secretase 1 | -6.98 | -7.44 | -7.96 | 74.77% | CHEMBL1917900 |
| Moexipril | BACE1_HUMAN | beta-secretase 1 | -6.50 | -7.39 | -7.54 | 63.33% | CHEMBL1917907 |
| Captopril | CAH2_HUMAN | carbonic anhydrase 2 | -5.96 | -5.92 | -5.53 | 59.42% | CHEMBL2023730 |
| Fosinopril | CAH2_HUMAN | carbonic anhydrase 2 | -7.58 | -8.01 | -7.82 | 40.20% | CHEMBL4059816 |
| Lisinopril | CAH2_HUMAN | carbonic anhydrase 2 | -7.07 | -7.72 | -7.41 | 54.05% | CHEMBL3314178 |
| Ramipril | CAH2_HUMAN | carbonic anhydrase 2 | -8.05 | -8.22 | -7.82 | 59.03% | CHEMBL4059816 |
| Moexipril | CAH2_HUMAN | carbonic anhydrase 2 | -7.94 | -8.56 | -8.28 | 57.54% | CHEMBL4067116 |
| Captopril | CASP1_HUMAN | caspase 1 | -4.59 | -4.82 | -4.34 | 50.62% | CHEMBL285638 |
| Fosinopril | CASP1_HUMAN | caspase 1 | -5.96 | -6.68 | -5.80 | 38.74% | CHEMBL317796 |
| Lisinopril | CASP1_HUMAN | caspase 1 | -5.69 | -6.89 | -5.36 | 71.57% | CHEMBL90884 |
| Ramipril | CASP1_HUMAN | caspase 1 | -6.15 | -8.16 | -6.18 | 65.79% | CHEMBL90884 |
| Moexipril | CASP1_HUMAN | caspase 1 | -7.35 | -7.68 | -6.24 | 50.63% | CHEMBL68583 |
| Captopril | CDK5_HUMAN | cyclin dependent kinase 5 | -5.74 | -5.93 | -5.90 | 26.44% | CHEMBL1994526 |
| Fosinopril | CDK5_HUMAN | cyclin dependent kinase 5 | -7.79 | -8.82 | -6.65 | 26.23% | CHEMBL422897 |
| Lisinopril | CDK5_HUMAN | cyclin dependent kinase 5 | -7.56 | -8.28 | -7.49 | 33.16% | CHEMBL1983111 |
| Ramipril | CDK5_HUMAN | cyclin dependent kinase 5 | -7.10 | -7.56 | -6.64 | 31.50% | CHEMBL1983111 |
| Moexipril | CDK5_HUMAN | cyclin dependent kinase 5 | -7.14 | -8.62 | -7.95 | 39.77% | CHEMBL1976240 |
| Captopril | CHLE_HUMAN | butyrylcholinesterase | -5.80 | -5.63 | -5.76 | 43.14% | CHEMBL4059766 |
| Fosinopril | CHLE_HUMAN | butyrylcholinesterase | -8.94 | -8.86 | -9.48 | 35.48% | CHEMBL4079599 |
| Lisinopril | CHLE_HUMAN | butyrylcholinesterase | -8.56 | -8.38 | -8.52 | 47.15% | CHEMBL4079599 |
| Ramipril | CHLE_HUMAN | butyrylcholinesterase | -9.27 | -8.77 | -9.43 | 56.00% | CHEMBL4079599 |
| Moexipril | CHLE_HUMAN | butyrylcholinesterase | -8.27 | -8.28 | -9.13 | 50.33% | CHEMBL3818250 |
| Captopril | CNR1_HUMAN | cannabinoid receptor 1 | -5.65 | -5.82 | -6.09 | 57.14% | CHEMBL483143 |
| Fosinopril | CNR1_HUMAN | cannabinoid receptor 1 | -7.08 | -9.37 | -10.35 | 36.52% | CHEMBL224259 |
| Lisinopril | CNR1_HUMAN | cannabinoid receptor 1 | -7.94 | -8.28 | -8.86 | 52.70% | CHEMBL510801 |
| Ramipril | CNR1_HUMAN | cannabinoid receptor 1 | -8.58 | -9.60 | -10.46 | 51.85% | CHEMBL175247 |
| Moexipril | CNR1_HUMAN | cannabinoid receptor 1 | -9.04 | -7.96 | -10.37 | 46.34% | CHEMBL228349 |
| Captopril | CNR2_HUMAN | cannabinoid receptor 2 | -6.24 | -5.67 | N/A | 50.00% | CHEMBL472661 |
| Fosinopril | CNR2_HUMAN | cannabinoid receptor 2 | -10.01 | -10.61 | N/A | 37.08% | CHEMBL1765287 |
| Lisinopril | CNR2_HUMAN | cannabinoid receptor 2 | -8.67 | -8.57 | N/A | 72.16% | CHEMBL1765271 |
| Ramipril | CNR2_HUMAN | cannabinoid receptor 2 | -9.06 | -9.79 | N/A | 68.38% | CHEMBL1765277 |
| Moexipril | CNR2_HUMAN | cannabinoid receptor 2 | -8.94 | -10.51 | N/A | 56.29% | CHEMBL3410730 |
| Captopril | COLI_HUMAN | proopiomelanocortin | -5.85 | -5.79 | -4.86 | N/A | N/A |
| Fosinopril | COLI_HUMAN | proopiomelanocortin | -8.02 | -8.19 | -7.78 | N/A | N/A |
| Lisinopril | COLI_HUMAN | proopiomelanocortin | -7.32 | -7.38 | -6.62 | N/A | N/A |
| Ramipril | COLI_HUMAN | proopiomelanocortin | -8.17 | -8.14 | -7.35 | N/A | N/A |
| Moexipril | COLI_HUMAN | proopiomelanocortin | -8.58 | -6.56 | -7.63 | N/A | N/A |
| Captopril | COMT_HUMAN | catechol-O-methyltransferase | -4.82 | -4.91 | -4.61 | 19.27% | CHEMBL3819488 |
| Fosinopril | COMT_HUMAN | catechol-O-methyltransferase | -6.43 | -5.94 | -6.21 | 23.21% | CHEMBL3819488 |
| Lisinopril | COMT_HUMAN | catechol-O-methyltransferase | -5.42 | -5.89 | -5.76 | 26.64% | CHEMBL3819488 |
| Ramipril | COMT_HUMAN | catechol-O-methyltransferase | -6.09 | -6.18 | -5.85 | 27.73% | CHEMBL3819488 |
| Moexipril | COMT_HUMAN | catechol-O-methyltransferase | -5.90 | -6.71 | -6.88 | 31.95% | CHEMBL3819488 |
| Captopril | CRP_HUMAN | C-reactive protein | -4.42 | -4.62 | N/A | N/A | N/A |
| Fosinopril | CRP_HUMAN | C-reactive protein | -5.61 | -5.48 | N/A | N/A | N/A |
| Lisinopril | CRP_HUMAN | C-reactive protein | -5.90 | -6.30 | N/A | N/A | N/A |
| Ramipril | CRP_HUMAN | C-reactive protein | -6.22 | -5.98 | N/A | N/A | N/A |
| Moexipril | CRP_HUMAN | C-reactive protein | -6.57 | -6.44 | N/A | N/A | N/A |
| Captopril | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.34 | N/A | N/A | 27.43% | CHEMBL556862 |
| Fosinopril | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | 1.00 | N/A | N/A | 29.60% | CHEMBL556862 |
| Lisinopril | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.50 | N/A | N/A | 36.02% | CHEMBL556862 |
| Ramipril | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -5.38 | N/A | N/A | 33.50% | CHEMBL556862 |
| Moexipril | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -1.58 | N/A | N/A | 33.33% | CHEMBL253495 |
| Captopril | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -5.33 | -4.60 | -5.04 | 39.29% | CHEMBL2370133 |
| Fosinopril | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -9.06 | -7.37 | -7.96 | 33.00% | CHEMBL1949890 |
| Lisinopril | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.24 | -6.67 | -6.89 | 58.77% | CHEMBL365952 |
| Ramipril | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.11 | -7.55 | -7.62 | 51.27% | CHEMBL2370133 |
| Moexipril | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -9.09 | -7.46 | -8.00 | 54.85% | CHEMBL3894327 |
| Captopril | DRD2_HUMAN | dopamine receptor D2 | -5.68 | N/A | N/A | 53.03% | CHEMBL317488 |
| Fosinopril | DRD2_HUMAN | dopamine receptor D2 | -7.48 | N/A | N/A | 36.41% | CHEMBL3676863 |
| Lisinopril | DRD2_HUMAN | dopamine receptor D2 | -6.80 | N/A | N/A | 50.82% | CHEMBL127114 |
| Ramipril | DRD2_HUMAN | dopamine receptor D2 | -7.42 | N/A | N/A | 55.17% | CHEMBL1221512 |
| Moexipril | DRD2_HUMAN | dopamine receptor D2 | -7.73 | N/A | N/A | 55.56% | CHEMBL2335740 |
| Captopril | DRD3_HUMAN | dopamine receptor D3 | -5.99 | N/A | N/A | 35.07% | CHEMBL1221512 |
| Fosinopril | DRD3_HUMAN | dopamine receptor D3 | -8.41 | N/A | N/A | 36.41% | CHEMBL3676863 |
| Lisinopril | DRD3_HUMAN | dopamine receptor D3 | -7.23 | N/A | N/A | 53.54% | CHEMBL117537 |
| Ramipril | DRD3_HUMAN | dopamine receptor D3 | -8.72 | N/A | N/A | 55.17% | CHEMBL1221512 |
| Moexipril | DRD3_HUMAN | dopamine receptor D3 | -8.74 | N/A | N/A | 54.22% | CHEMBL3780140 |
| Captopril | DRD4_HUMAN | dopamine receptor D4 | -5.67 | -5.90 | N/A | 32.97% | CHEMBL20444 |
| Fosinopril | DRD4_HUMAN | dopamine receptor D4 | -9.61 | -9.54 | N/A | 31.66% | CHEMBL3318835 |
| Lisinopril | DRD4_HUMAN | dopamine receptor D4 | -7.96 | -8.65 | N/A | 53.54% | CHEMBL117537 |
| Ramipril | DRD4_HUMAN | dopamine receptor D4 | -8.96 | -8.81 | N/A | 49.12% | CHEMBL3335544 |
| Moexipril | DRD4_HUMAN | dopamine receptor D4 | -9.11 | -9.40 | N/A | 52.53% | CHEMBL2334891 |
| Captopril | EDN1_HUMAN | endothelin 1 | -5.44 | N/A | N/A | N/A | N/A |
| Fosinopril | EDN1_HUMAN | endothelin 1 | -7.75 | N/A | N/A | N/A | N/A |
| Lisinopril | EDN1_HUMAN | endothelin 1 | -7.67 | N/A | N/A | N/A | N/A |
| Ramipril | EDN1_HUMAN | endothelin 1 | -8.40 | N/A | N/A | N/A | N/A |
| Moexipril | EDN1_HUMAN | endothelin 1 | -8.87 | N/A | N/A | N/A | N/A |
| Captopril | ESR1_HUMAN | estrogen receptor 1 | -5.90 | -5.67 | -5.56 | 43.04% | CHEMBL3597502 |
| Fosinopril | ESR1_HUMAN | estrogen receptor 1 | -7.51 | -6.81 | -7.03 | 40.00% | CHEMBL4075710 |
| Lisinopril | ESR1_HUMAN | estrogen receptor 1 | -8.12 | -7.29 | -7.72 | 53.33% | CHEMBL1222035 |
| Ramipril | ESR1_HUMAN | estrogen receptor 1 | -7.44 | -7.44 | -7.93 | 54.90% | CHEMBL4075710 |
| Moexipril | ESR1_HUMAN | estrogen receptor 1 | -6.59 | -7.36 | -7.55 | 58.79% | CHEMBL241041 |
| Captopril | FABP5_HUMAN | fatty acid binding protein 5 | -5.36 | -4.50 | -4.56 | 25.42% | CHEMBL82293 |
| Fosinopril | FABP5_HUMAN | fatty acid binding protein 5 | -8.52 | -5.91 | -5.50 | 20.08% | CHEMBL3950316 |
| Lisinopril | FABP5_HUMAN | fatty acid binding protein 5 | -8.06 | -5.52 | -5.21 | 24.14% | CHEMBL3941588 |
| Ramipril | FABP5_HUMAN | fatty acid binding protein 5 | -8.55 | -6.10 | -5.80 | 22.99% | CHEMBL3941588 |
| Moexipril | FABP5_HUMAN | fatty acid binding protein 5 | -9.05 | -6.54 | -5.57 | 28.00% | CHEMBL247920 |
| Captopril | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -5.42 | N/A | N/A | 49.40% | CHEMBL407135 |
| Fosinopril | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -8.44 | N/A | N/A | 32.02% | CHEMBL432649 |
| Lisinopril | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -7.92 | N/A | N/A | 50.98% | CHEMBL407135 |
| Ramipril | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -7.95 | N/A | N/A | 55.17% | CHEMBL1221512 |
| Moexipril | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -8.48 | N/A | N/A | 44.68% | CHEMBL1221512 |
| Captopril | GLRA3_HUMAN | glycine receptor alpha 3 | -6.33 | -6.73 | -6.81 | 16.11% | CHEMBL4070615 |
| Captopril | GLRA3_HUMAN | glycine receptor alpha 3 | -5.87 | N/A | N/A | 16.11% | CHEMBL4070615 |
| Fosinopril | GLRA3_HUMAN | glycine receptor alpha 3 | -8.93 | -9.30 | -8.87 | 22.26% | CHEMBL4070615 |
| Fosinopril | GLRA3_HUMAN | glycine receptor alpha 3 | -9.11 | N/A | N/A | 22.26% | CHEMBL4070615 |
| Lisinopril | GLRA3_HUMAN | glycine receptor alpha 3 | -7.94 | -8.10 | -7.97 | 23.87% | CHEMBL4070615 |
| Lisinopril | GLRA3_HUMAN | glycine receptor alpha 3 | -8.00 | N/A | N/A | 23.87% | CHEMBL4070615 |
| Ramipril | GLRA3_HUMAN | glycine receptor alpha 3 | -8.57 | -9.17 | -9.06 | 22.98% | CHEMBL4070615 |
| Ramipril | GLRA3_HUMAN | glycine receptor alpha 3 | -9.03 | N/A | N/A | 22.98% | CHEMBL4070615 |
| Moexipril | GLRA3_HUMAN | glycine receptor alpha 3 | -9.06 | -8.62 | -9.05 | 30.23% | CHEMBL4070615 |
| Moexipril | GLRA3_HUMAN | glycine receptor alpha 3 | -8.45 | N/A | N/A | 30.23% | CHEMBL4070615 |
| Captopril | GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.49 | -5.83 | -5.82 | 45.90% | CHEMBL1783985 |
| Fosinopril | GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.51 | -0.95 | -4.17 | 30.11% | CHEMBL92162 |
| Lisinopril | GRM5_HUMAN | glutamate metabotropic receptor 5 | -8.37 | -7.76 | -7.92 | 41.32% | CHEMBL92162 |
| Ramipril | GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.16 | -6.49 | -5.96 | 43.70% | CHEMBL1289349 |
| Moexipril | GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.64 | -6.64 | -6.24 | 39.77% | CHEMBL1684103 |
| Captopril | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -5.40 | -5.54 | -6.20 | 25.76% | CHEMBL3650224 |
| Fosinopril | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.42 | -7.84 | -7.54 | 24.19% | CHEMBL3650224 |
| Lisinopril | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.12 | -6.62 | -6.85 | 34.25% | CHEMBL3650224 |
| Ramipril | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.82 | -7.16 | -7.09 | 37.25% | CHEMBL3650224 |
| Moexipril | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.52 | -7.30 | -7.34 | 38.74% | CHEMBL3903606 |
| Captopril | HRH1_HUMAN | histamine receptor H1 | -5.59 | N/A | N/A | 32.74% | CHEMBL2158793 |
| Fosinopril | HRH1_HUMAN | histamine receptor H1 | -5.70 | N/A | N/A | 32.28% | CHEMBL1277311 |
| Lisinopril | HRH1_HUMAN | histamine receptor H1 | -7.83 | N/A | N/A | 56.14% | CHEMBL1278113 |
| Ramipril | HRH1_HUMAN | histamine receptor H1 | -7.75 | N/A | N/A | 52.38% | CHEMBL1278113 |
| Moexipril | HRH1_HUMAN | histamine receptor H1 | -6.66 | N/A | N/A | 49.36% | CHEMBL3817898 |
| Captopril | HYES_HUMAN | epoxide hydrolase 2 | -6.08 | -6.09 | -6.23 | 62.86% | CHEMBL376597 |
| Fosinopril | HYES_HUMAN | epoxide hydrolase 2 | -8.50 | -8.51 | -8.63 | 38.80% | CHEMBL216164 |
| Lisinopril | HYES_HUMAN | epoxide hydrolase 2 | -8.12 | -8.08 | -7.30 | 75.96% | CHEMBL216164 |
| Ramipril | HYES_HUMAN | epoxide hydrolase 2 | -8.41 | -8.45 | -8.30 | 66.95% | CHEMBL216164 |
| Moexipril | HYES_HUMAN | epoxide hydrolase 2 | -7.91 | -8.83 | -8.23 | 51.53% | CHEMBL219132 |
| Captopril | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -5.53 | N/A | N/A | 28.21% | CHEMBL1672879 |
| Fosinopril | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -7.67 | N/A | N/A | 26.36% | CHEMBL4083511 |
| Lisinopril | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -7.18 | N/A | N/A | 35.85% | CHEMBL2208034 |
| Ramipril | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -7.96 | N/A | N/A | 37.72% | CHEMBL2208034 |
| Moexipril | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -8.37 | N/A | N/A | 33.12% | CHEMBL3917180 |
| Captopril | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -5.63 | -5.15 | N/A | 62.30% | CHEMBL2075030 |
| Fosinopril | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -6.91 | -10.12 | N/A | 37.84% | CHEMBL350775 |
| Lisinopril | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -7.57 | -7.38 | N/A | 64.96% | CHEMBL1790684 |
| Ramipril | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -8.40 | -8.99 | N/A | 71.07% | CHEMBL1790684 |
| Moexipril | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -8.52 | -8.72 | N/A | 56.69% | CHEMBL3352978 |
| Captopril | MIF_HUMAN | macrophage migration inhibitory factor | -4.70 | -5.65 | -4.84 | 18.99% | CHEMBL554271 |
| Fosinopril | MIF_HUMAN | macrophage migration inhibitory factor | -6.85 | -6.83 | -6.25 | 27.31% | CHEMBL554271 |
| Lisinopril | MIF_HUMAN | macrophage migration inhibitory factor | -6.88 | -7.03 | -6.01 | 32.12% | CHEMBL554271 |
| Ramipril | MIF_HUMAN | macrophage migration inhibitory factor | -6.59 | -7.77 | -6.34 | 32.70% | CHEMBL497598 |
| Moexipril | MIF_HUMAN | macrophage migration inhibitory factor | -6.93 | -7.04 | -6.51 | 37.57% | CHEMBL3797437 |
| Captopril | MK01_HUMAN | mitogen-activated protein kinase 1 | -5.15 | -4.97 | -5.06 | 41.90% | CHEMBL3752989 |
| Fosinopril | MK01_HUMAN | mitogen-activated protein kinase 1 | -7.86 | -7.85 | -8.01 | 36.61% | CHEMBL3752989 |
| Lisinopril | MK01_HUMAN | mitogen-activated protein kinase 1 | -6.80 | -7.04 | -7.12 | 75.49% | CHEMBL3752989 |
| Ramipril | MK01_HUMAN | mitogen-activated protein kinase 1 | -7.40 | -7.22 | -7.64 | 64.96% | CHEMBL3752989 |
| Moexipril | MK01_HUMAN | mitogen-activated protein kinase 1 | -7.31 | -7.76 | -8.48 | 53.85% | CHEMBL3752989 |
| Captopril | MK03_HUMAN | mitogen-activated protein kinase 3 | -5.88 | -5.95 | -5.24 | 30.43% | CHEMBL3113587 |
| Fosinopril | MK03_HUMAN | mitogen-activated protein kinase 3 | -8.01 | -9.33 | -8.12 | 30.05% | CHEMBL3113587 |
| Lisinopril | MK03_HUMAN | mitogen-activated protein kinase 3 | -7.28 | -7.59 | -6.86 | 51.26% | CHEMBL3113587 |
| Ramipril | MK03_HUMAN | mitogen-activated protein kinase 3 | -8.11 | -8.26 | -7.76 | 48.09% | CHEMBL3113587 |
| Moexipril | MK03_HUMAN | mitogen-activated protein kinase 3 | -7.96 | -7.98 | -8.26 | 34.64% | CHEMBL3113587 |
| Captopril | MTOR_HUMAN | mechanistic target of rapamycin kinase | -5.50 | -5.75 | -5.68 | 38.89% | CHEMBL3972399 |
| Fosinopril | MTOR_HUMAN | mechanistic target of rapamycin kinase | -9.56 | -9.68 | -9.76 | 39.23% | CHEMBL371029 |
| Lisinopril | MTOR_HUMAN | mechanistic target of rapamycin kinase | -8.08 | -8.25 | -7.98 | 56.03% | CHEMBL371029 |
| Ramipril | MTOR_HUMAN | mechanistic target of rapamycin kinase | -8.48 | -8.44 | -9.02 | 65.96% | CHEMBL371029 |
| Moexipril | MTOR_HUMAN | mechanistic target of rapamycin kinase | -9.28 | -9.48 | -9.37 | 51.96% | CHEMBL4100500 |
| Captopril | NEP_HUMAN | membrane metalloendopeptidase | -5.29 | -5.89 | -6.66 | 75.81% | CHEMBL3298939 |
| Fosinopril | NEP_HUMAN | membrane metalloendopeptidase | -7.27 | -6.86 | -8.21 | 40.23% | CHEMBL148840 |
| Lisinopril | NEP_HUMAN | membrane metalloendopeptidase | -7.47 | -7.14 | -7.73 | 77.67% | CHEMBL1778526 |
| Ramipril | NEP_HUMAN | membrane metalloendopeptidase | -7.34 | -7.51 | -8.53 | 71.30% | CHEMBL1778526 |
| Moexipril | NEP_HUMAN | membrane metalloendopeptidase | -7.32 | -7.80 | -7.80 | 60.74% | CHEMBL51576 |
| Captopril | NK1R_HUMAN | tachykinin receptor 1 | -5.80 | -5.86 | -5.55 | 45.63% | CHEMBL156933 |
| Fosinopril | NK1R_HUMAN | tachykinin receptor 1 | -8.92 | -8.12 | -7.99 | 37.70% | CHEMBL3085126 |
| Lisinopril | NK1R_HUMAN | tachykinin receptor 1 | -7.65 | -7.77 | -7.22 | 65.26% | CHEMBL2396664 |
| Ramipril | NK1R_HUMAN | tachykinin receptor 1 | -8.62 | -8.03 | -7.58 | 58.33% | CHEMBL3707331 |
| Moexipril | NK1R_HUMAN | tachykinin receptor 1 | -8.68 | -8.50 | -8.57 | 55.76% | CHEMBL278455 |
| Captopril | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -5.51 | -5.77 | -5.63 | 11.43% | CHEMBL2333945 |
| Fosinopril | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -7.45 | -7.65 | -7.68 | 18.13% | CHEMBL284237 |
| Lisinopril | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -8.09 | -7.91 | -8.04 | 24.60% | CHEMBL284237 |
| Ramipril | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -7.93 | -7.88 | -7.57 | 22.14% | CHEMBL284237 |
| Moexipril | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -7.97 | -7.61 | -7.84 | 32.93% | CHEMBL284237 |
| Captopril | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -6.14 | -6.06 | -5.96 | 28.16% | CHEMBL217955 |
| Fosinopril | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -9.25 | -9.36 | -7.85 | 26.59% | CHEMBL305187 |
| Lisinopril | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -8.48 | -8.78 | -8.48 | 45.19% | CHEMBL17350 |
| Ramipril | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -9.29 | -8.88 | -8.50 | 40.37% | CHEMBL3357791 |
| Moexipril | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -9.11 | -9.29 | -8.23 | 41.87% | CHEMBL1289403 |
| Captopril | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -5.61 | -5.69 | -5.63 | 20.34% | CHEMBL354003 |
| Fosinopril | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -7.46 | -6.93 | -7.68 | 25.60% | CHEMBL354003 |
| Lisinopril | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -8.08 | -7.84 | -8.04 | 33.52% | CHEMBL354003 |
| Ramipril | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -8.00 | -7.90 | -7.57 | 31.12% | CHEMBL354003 |
| Moexipril | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -7.92 | -7.17 | -7.84 | 33.33% | CHEMBL354003 |
| Captopril | NOS1_HUMAN | nitric oxide synthase 1 | -6.57 | -6.36 | -6.25 | 50.00% | CHEMBL11471 |
| Fosinopril | NOS1_HUMAN | nitric oxide synthase 1 | -8.76 | -9.30 | -8.86 | 27.55% | CHEMBL1270460 |
| Lisinopril | NOS1_HUMAN | nitric oxide synthase 1 | -8.23 | -8.50 | -8.51 | 42.86% | CHEMBL317521 |
| Ramipril | NOS1_HUMAN | nitric oxide synthase 1 | -8.96 | -8.87 | -8.52 | 43.70% | CHEMBL317521 |
| Moexipril | NOS1_HUMAN | nitric oxide synthase 1 | -8.76 | -8.89 | -8.79 | 36.22% | CHEMBL1230380 |
| Captopril | NOS2_HUMAN | nitric oxide synthase 2 | -6.11 | -6.24 | -6.26 | 50.00% | CHEMBL11471 |
| Fosinopril | NOS2_HUMAN | nitric oxide synthase 2 | -6.88 | -8.47 | 7.14 | 26.52% | CHEMBL1911987 |
| Lisinopril | NOS2_HUMAN | nitric oxide synthase 2 | -8.39 | -8.17 | -8.35 | 36.56% | CHEMBL7889 |
| Ramipril | NOS2_HUMAN | nitric oxide synthase 2 | -8.19 | -8.67 | -8.51 | 31.98% | CHEMBL427062 |
| Moexipril | NOS2_HUMAN | nitric oxide synthase 2 | -6.98 | -9.26 | -3.40 | 42.54% | CHEMBL222364 |
| Captopril | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -5.61 | -5.69 | -5.63 | 21.95% | CHEMBL539474 |
| Fosinopril | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -8.12 | -8.95 | -9.16 | 28.91% | CHEMBL3675911 |
| Lisinopril | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -7.78 | -8.48 | -8.45 | 35.90% | CHEMBL3966401 |
| Ramipril | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -8.32 | -8.89 | -9.08 | 35.12% | CHEMBL4113377 |
| Moexipril | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -8.32 | -8.69 | -8.89 | 41.03% | CHEMBL3408947 |
| Captopril | OPRD_HUMAN | opioid receptor delta 1 | -4.90 | -5.02 | -4.77 | 48.42% | CHEMBL437983 |
| Fosinopril | OPRD_HUMAN | opioid receptor delta 1 | -7.75 | -7.51 | -7.91 | 42.35% | CHEMBL401508 |
| Lisinopril | OPRD_HUMAN | opioid receptor delta 1 | -6.93 | -6.25 | -6.83 | 73.33% | CHEMBL574143 |
| Ramipril | OPRD_HUMAN | opioid receptor delta 1 | -7.54 | -7.18 | -7.30 | 64.60% | CHEMBL3912914 |
| Moexipril | OPRD_HUMAN | opioid receptor delta 1 | -6.62 | -6.92 | -7.16 | 80.41% | CHEMBL297452 |
| Captopril | OPRK_HUMAN | opioid receptor kappa 1 | -5.71 | -5.52 | -5.62 | 48.42% | CHEMBL437983 |
| Fosinopril | OPRK_HUMAN | opioid receptor kappa 1 | -9.88 | -8.79 | -9.06 | 41.86% | CHEMBL270401 |
| Lisinopril | OPRK_HUMAN | opioid receptor kappa 1 | -8.26 | -7.87 | -7.66 | 76.47% | CHEMBL4108083 |
| Ramipril | OPRK_HUMAN | opioid receptor kappa 1 | -9.24 | -8.43 | -8.50 | 66.10% | CHEMBL4110548 |
| Moexipril | OPRK_HUMAN | opioid receptor kappa 1 | -9.61 | -8.66 | -8.30 | 71.07% | CHEMBL76089 |
| Captopril | OPRM_MOUSE | Mu-type opioid receptor | -5.58 | -5.29 | N/A | 41.58% | CHEMBL8234 |
| Fosinopril | OPRM_MOUSE | Mu-type opioid receptor | -9.42 | -8.46 | N/A | 39.23% | CHEMBL402691 |
| Lisinopril | OPRM_MOUSE | Mu-type opioid receptor | -7.25 | -7.17 | N/A | 71.56% | CHEMBL2370690 |
| Ramipril | OPRM_MOUSE | Mu-type opioid receptor | -7.94 | -8.04 | N/A | 62.10% | CHEMBL2370690 |
| Moexipril | OPRM_MOUSE | Mu-type opioid receptor | -7.86 | -8.66 | N/A | 62.20% | CHEMBL330991 |
| Captopril | OPRX_HUMAN | opioid related nociceptin receptor 1 | -4.96 | -4.92 | -4.98 | 41.67% | CHEMBL384866 |
| Fosinopril | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.69 | -7.32 | -8.03 | 35.64% | CHEMBL265801 |
| Lisinopril | OPRX_HUMAN | opioid related nociceptin receptor 1 | -6.96 | -7.22 | -7.43 | 67.57% | CHEMBL437915 |
| Ramipril | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.74 | -7.95 | -7.86 | 58.73% | CHEMBL437915 |
| Moexipril | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.50 | -7.35 | -7.55 | 51.59% | CHEMBL3785728 |
| Captopril | P2RX3_HUMAN | purinergic receptor P2X 3 | -4.20 | -4.20 | -4.40 | 33.58% | CHEMBL395723 |
| Fosinopril | P2RX3_HUMAN | purinergic receptor P2X 3 | -5.59 | -5.37 | -5.11 | 32.13% | CHEMBL3669852 |
| Lisinopril | P2RX3_HUMAN | purinergic receptor P2X 3 | -4.93 | -5.24 | -5.80 | 54.35% | CHEMBL395723 |
| Ramipril | P2RX3_HUMAN | purinergic receptor P2X 3 | -5.70 | -5.86 | -5.55 | 49.68% | CHEMBL3669852 |
| Moexipril | P2RX3_HUMAN | purinergic receptor P2X 3 | -6.18 | -6.22 | -6.51 | 47.31% | CHEMBL395723 |
| Captopril | P2Y12_HUMAN | purinergic receptor P2Y12 | -5.37 | -5.55 | -5.95 | 32.59% | CHEMBL88108 |
| Fosinopril | P2Y12_HUMAN | purinergic receptor P2Y12 | -9.16 | -6.76 | -8.13 | 32.94% | CHEMBL3652608 |
| Lisinopril | P2Y12_HUMAN | purinergic receptor P2Y12 | -7.74 | -8.09 | -8.53 | 43.28% | CHEMBL88708 |
| Ramipril | P2Y12_HUMAN | purinergic receptor P2Y12 | -7.81 | -6.64 | -8.32 | 41.78% | CHEMBL599606 |
| Moexipril | P2Y12_HUMAN | purinergic receptor P2Y12 | -9.50 | -8.77 | -9.29 | 45.05% | CHEMBL3652613 |
| Captopril | PAR1_HUMAN | coagulation factor II thrombin receptor | -6.20 | N/A | N/A | 50.67% | CHEMBL76719 |
| Fosinopril | PAR1_HUMAN | coagulation factor II thrombin receptor | -8.21 | N/A | N/A | 32.52% | CHEMBL80942 |
| Lisinopril | PAR1_HUMAN | coagulation factor II thrombin receptor | -7.95 | N/A | N/A | 60.55% | CHEMBL133837 |
| Ramipril | PAR1_HUMAN | coagulation factor II thrombin receptor | -8.05 | N/A | N/A | 53.98% | CHEMBL3658406 |
| Moexipril | PAR1_HUMAN | coagulation factor II thrombin receptor | -9.26 | N/A | N/A | 48.59% | CHEMBL80942 |
| Captopril | PDE4B_HUMAN | phosphodiesterase 4B | -5.69 | -5.93 | -5.54 | 27.64% | CHEMBL144499 |
| Fosinopril | PDE4B_HUMAN | phosphodiesterase 4B | -8.61 | -8.28 | -8.78 | 33.68% | CHEMBL144499 |
| Lisinopril | PDE4B_HUMAN | phosphodiesterase 4B | -8.16 | -8.61 | -8.51 | 47.24% | CHEMBL144499 |
| Ramipril | PDE4B_HUMAN | phosphodiesterase 4B | -8.43 | -8.59 | -8.76 | 47.79% | CHEMBL144499 |
| Moexipril | PDE4B_HUMAN | phosphodiesterase 4B | -8.56 | -9.70 | -8.96 | 62.15% | CHEMBL4076662 |
| Captopril | PDE5A_HUMAN | phosphodiesterase 5A | -5.66 | -6.08 | -5.77 | 25.95% | CHEMBL190423 |
| Fosinopril | PDE5A_HUMAN | phosphodiesterase 5A | -8.68 | -9.97 | -8.74 | 29.13% | CHEMBL190423 |
| Lisinopril | PDE5A_HUMAN | phosphodiesterase 5A | -8.19 | -8.53 | -7.60 | 37.32% | CHEMBL190423 |
| Ramipril | PDE5A_HUMAN | phosphodiesterase 5A | -7.96 | -8.73 | -8.46 | 35.71% | CHEMBL190423 |
| Moexipril | PDE5A_HUMAN | phosphodiesterase 5A | -8.09 | -8.95 | -8.43 | 56.76% | CHEMBL30936 |
| Captopril | PERM_HUMAN | myeloperoxidase | -5.09 | -5.25 | -5.01 | 23.08% | CHEMBL2347029 |
| Fosinopril | PERM_HUMAN | myeloperoxidase | -8.63 | -8.77 | -7.94 | 26.29% | CHEMBL2347029 |
| Lisinopril | PERM_HUMAN | myeloperoxidase | -7.95 | -8.10 | -7.50 | 38.10% | CHEMBL2347029 |
| Ramipril | PERM_HUMAN | myeloperoxidase | -8.29 | -8.55 | -7.83 | 35.25% | CHEMBL2347029 |
| Moexipril | PERM_HUMAN | myeloperoxidase | -8.10 | -7.97 | -7.87 | 33.33% | CHEMBL3899797 |
| Captopril | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -5.78 | -6.34 | -5.58 | 39.05% | CHEMBL3809863 |
| Fosinopril | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -5.52 | -6.85 | -6.20 | 30.00% | CHEMBL3809863 |
| Lisinopril | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -8.14 | -7.55 | -7.49 | 54.39% | CHEMBL3809863 |
| Ramipril | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -7.54 | -8.86 | -6.61 | 49.61% | CHEMBL3809863 |
| Moexipril | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -6.21 | -7.29 | -8.04 | 42.03% | CHEMBL24798 |
| Captopril | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -5.09 | -5.46 | -5.53 | 53.03% | CHEMBL3809958 |
| Fosinopril | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -2.11 | -5.87 | -7.09 | 35.16% | CHEMBL3809156 |
| Lisinopril | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -6.10 | -6.39 | -6.72 | 73.96% | CHEMBL3809116 |
| Ramipril | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -5.45 | -6.08 | -7.08 | 70.27% | CHEMBL3809156 |
| Moexipril | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -2.19 | -4.68 | -7.19 | 56.29% | CHEMBL3809156 |
| Captopril | PPAP_HUMAN | acid phosphatase 3 | -6.10 | N/A | N/A | 10.00% | CHEMBL501717 |
| Fosinopril | PPAP_HUMAN | acid phosphatase 3 | -9.07 | N/A | N/A | 21.03% | CHEMBL507996 |
| Lisinopril | PPAP_HUMAN | acid phosphatase 3 | -7.50 | N/A | N/A | 21.77% | CHEMBL501717 |
| Ramipril | PPAP_HUMAN | acid phosphatase 3 | -7.61 | N/A | N/A | 20.44% | CHEMBL501717 |
| Moexipril | PPAP_HUMAN | acid phosphatase 3 | -7.35 | N/A | N/A | 29.89% | CHEMBL507996 |
| Captopril | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -5.18 | -5.35 | -5.12 | 37.35% | CHEMBL1836976 |
| Fosinopril | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -8.67 | -8.94 | -7.56 | 31.19% | CHEMBL2208197 |
| Lisinopril | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -7.29 | -8.05 | -7.47 | 42.38% | CHEMBL2208197 |
| Ramipril | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -7.57 | -7.51 | -7.31 | 41.94% | CHEMBL83875 |
| Moexipril | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -8.19 | -9.34 | -8.21 | 48.63% | CHEMBL317424 |
| Captopril | PRGR_HUMAN | progesterone receptor | -6.20 | -6.26 | -6.01 | 30.92% | CHEMBL436859 |
| Fosinopril | PRGR_HUMAN | progesterone receptor | -2.95 | -2.03 | -7.37 | 33.78% | CHEMBL414318 |
| Lisinopril | PRGR_HUMAN | progesterone receptor | -8.22 | -7.54 | -8.12 | 43.13% | CHEMBL436859 |
| Ramipril | PRGR_HUMAN | progesterone receptor | -7.89 | -7.66 | -8.66 | 47.24% | CHEMBL414318 |
| Moexipril | PRGR_HUMAN | progesterone receptor | -4.90 | -3.09 | -8.41 | 42.33% | CHEMBL1163975 |
| Captopril | PTGES_HUMAN | prostaglandin E synthase | -4.92 | N/A | N/A | 34.69% | CHEMBL3919693 |
| Fosinopril | PTGES_HUMAN | prostaglandin E synthase | -6.86 | N/A | N/A | 28.86% | CHEMBL4085873 |
| Lisinopril | PTGES_HUMAN | prostaglandin E synthase | -7.00 | N/A | N/A | 41.54% | CHEMBL4071976 |
| Ramipril | PTGES_HUMAN | prostaglandin E synthase | -7.87 | N/A | N/A | 38.46% | CHEMBL4071976 |
| Moexipril | PTGES_HUMAN | prostaglandin E synthase | -7.69 | N/A | N/A | 35.43% | CHEMBL3770829 |
| Captopril | SC6A4_HUMAN | solute carrier family 6 member 4 | -5.83 | -6.32 | -6.39 | 38.04% | CHEMBL3940791 |
| Fosinopril | SC6A4_HUMAN | solute carrier family 6 member 4 | -9.70 | -10.06 | -9.43 | 37.77% | CHEMBL86590 |
| Lisinopril | SC6A4_HUMAN | solute carrier family 6 member 4 | -8.60 | -8.00 | -8.63 | 57.41% | CHEMBL315172 |
| Ramipril | SC6A4_HUMAN | solute carrier family 6 member 4 | -9.03 | -8.75 | -9.11 | 58.62% | CHEMBL315172 |
| Moexipril | SC6A4_HUMAN | solute carrier family 6 member 4 | -10.02 | -9.65 | -9.96 | 57.49% | CHEMBL264430 |
| Captopril | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -6.10 | N/A | N/A | 30.56% | CHEMBL206758 |
| Fosinopril | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.42 | N/A | N/A | 33.70% | CHEMBL206758 |
| Lisinopril | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.34 | N/A | N/A | 48.70% | CHEMBL206758 |
| Ramipril | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.81 | N/A | N/A | 47.06% | CHEMBL3341996 |
| Moexipril | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.29 | N/A | N/A | 55.11% | CHEMBL2164397 |
| Captopril | TLR4_HUMAN | toll like receptor 4 | -4.95 | -5.47 | -5.75 | 25.81% | CHEMBL3354641 |
| Fosinopril | TLR4_HUMAN | toll like receptor 4 | -8.48 | -8.15 | -8.39 | 39.60% | CHEMBL382272 |
| Lisinopril | TLR4_HUMAN | toll like receptor 4 | -7.30 | -6.94 | -7.17 | 39.74% | CHEMBL382272 |
| Ramipril | TLR4_HUMAN | toll like receptor 4 | -8.13 | -7.82 | -7.45 | 49.01% | CHEMBL382272 |
| Moexipril | TLR4_HUMAN | toll like receptor 4 | -6.87 | -7.50 | -7.75 | 38.78% | CHEMBL382272 |
| Captopril | TNFA_HUMAN | tumor necrosis factor | -5.21 | N/A | N/A | 32.64% | CHEMBL3806296 |
| Fosinopril | TNFA_HUMAN | tumor necrosis factor | -7.00 | N/A | N/A | 32.73% | CHEMBL3806296 |
| Lisinopril | TNFA_HUMAN | tumor necrosis factor | -7.12 | N/A | N/A | 55.63% | CHEMBL3806296 |
| Ramipril | TNFA_HUMAN | tumor necrosis factor | -7.79 | N/A | N/A | 49.68% | CHEMBL3806296 |
| Moexipril | TNFA_HUMAN | tumor necrosis factor | -7.35 | N/A | N/A | 50.29% | CHEMBL114343 |
| Captopril | TRBM_HUMAN | thrombomodulin | -5.80 | -5.22 | N/A | N/A | N/A |
| Fosinopril | TRBM_HUMAN | thrombomodulin | -7.87 | -6.61 | N/A | N/A | N/A |
| Lisinopril | TRBM_HUMAN | thrombomodulin | -7.66 | -6.55 | N/A | N/A | N/A |
| Ramipril | TRBM_HUMAN | thrombomodulin | -8.47 | -7.16 | N/A | N/A | N/A |
| Moexipril | TRBM_HUMAN | thrombomodulin | -8.42 | -7.21 | N/A | N/A | N/A |
| Captopril | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -5.53 | -5.58 | N/A | N/A | N/A |
| Fosinopril | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -6.67 | -6.39 | N/A | N/A | N/A |
| Lisinopril | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -7.79 | -7.22 | N/A | N/A | N/A |
| Ramipril | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -7.81 | -5.84 | N/A | N/A | N/A |
| Moexipril | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -7.35 | -7.75 | N/A | N/A | N/A |
| Captopril | TRPM8_FICAL | Uncharacterized protein | -5.88 | N/A | N/A | N/A | N/A |
| Fosinopril | TRPM8_FICAL | Uncharacterized protein | -10.09 | N/A | N/A | N/A | N/A |
| Lisinopril | TRPM8_FICAL | Uncharacterized protein | -8.19 | N/A | N/A | N/A | N/A |
| Ramipril | TRPM8_FICAL | Uncharacterized protein | -9.00 | N/A | N/A | N/A | N/A |
| Moexipril | TRPM8_FICAL | Uncharacterized protein | -9.87 | N/A | N/A | N/A | N/A |
| Captopril | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -5.66 | N/A | N/A | 47.44% | CHEMBL73188 |
| Fosinopril | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -8.57 | N/A | N/A | 33.69% | CHEMBL101775 |
| Lisinopril | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -7.60 | N/A | N/A | 49.53% | CHEMBL237138 |
| Ramipril | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -8.24 | N/A | N/A | 45.65% | CHEMBL254663 |
| Moexipril | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -8.39 | N/A | N/A | 48.85% | CHEMBL239389 |
| Captopril | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -5.76 | -6.19 | N/A | N/A | N/A |
| Fosinopril | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -6.70 | -7.66 | N/A | N/A | N/A |
| Lisinopril | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -6.42 | -6.42 | N/A | N/A | N/A |
| Ramipril | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -8.78 | -7.87 | N/A | N/A | N/A |
| Moexipril | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -6.37 | -7.88 | N/A | N/A | N/A |
| Captopril | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -4.68 | -5.62 | N/A | 47.44% | CHEMBL73188 |
| Fosinopril | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -8.16 | -5.98 | N/A | 30.73% | CHEMBL3664218 |
| Lisinopril | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -6.21 | -6.43 | N/A | 38.96% | CHEMBL3664218 |
| Ramipril | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -7.15 | -7.20 | N/A | 39.88% | CHEMBL3664218 |
| Moexipril | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -7.35 | -6.94 | N/A | 47.85% | CHEMBL3664218 |
| Captopril | TRXR1_HUMAN | thioredoxin reductase 1 | -5.61 | -6.27 | -4.38 | N/A | N/A |
| Fosinopril | TRXR1_HUMAN | thioredoxin reductase 1 | -8.40 | -7.79 | -6.11 | N/A | N/A |
| Lisinopril | TRXR1_HUMAN | thioredoxin reductase 1 | -7.27 | -7.04 | -6.03 | N/A | N/A |
| Ramipril | TRXR1_HUMAN | thioredoxin reductase 1 | -7.98 | -8.77 | -6.72 | N/A | N/A |
| Moexipril | TRXR1_HUMAN | thioredoxin reductase 1 | -7.31 | -7.61 | -6.13 | N/A | N/A |
| Captopril | TRY1_HUMAN | serine protease 1 | -4.51 | N/A | N/A | 49.30% | CHEMBL289395 |
| Fosinopril | TRY1_HUMAN | serine protease 1 | -6.34 | N/A | N/A | 38.50% | CHEMBL70350 |
| Lisinopril | TRY1_HUMAN | serine protease 1 | -6.23 | N/A | N/A | 75.53% | CHEMBL408125 |
| Ramipril | TRY1_HUMAN | serine protease 1 | -6.50 | N/A | N/A | 65.74% | CHEMBL408125 |
| Moexipril | TRY1_HUMAN | serine protease 1 | -6.72 | N/A | N/A | 52.13% | CHEMBL366921 |