![](/g/images/s/5HT1B_HUMAN-orthosteric-model_1.png) |
5-hydroxytryptamine receptor 1B
|
Homo sapiens; Human |
5HT1B_HUMAN
|
HTR1B |
P28222
|
CHEMBL1898
|
2475 / 2634
|
![](/g/images/s/5HT2A_HUMAN-orthosteric-model_1.png) |
5-hydroxytryptamine receptor 2A
|
Homo sapiens; Human |
5HT2A_HUMAN
|
HTR2A |
P28223
|
CHEMBL224
|
8589 / 10505
|
![](/g/images/s/5HT2B_HUMAN-orthosteric-model_1.png) |
5-hydroxytryptamine receptor 2B
|
Homo sapiens; Human |
5HT2B_HUMAN
|
HTR2B |
P41595
|
CHEMBL1833
|
4230 / 5981
|
![](/g/images/s/5HT2C_HUMAN-orthosteric-model_1.png) |
5-hydroxytryptamine receptor 2C
|
Homo sapiens; Human |
5HT2C_HUMAN
|
HTR2C |
P28335
|
CHEMBL225
|
7347 / 9196
|
![](/g/images/s/AA1R_HUMAN-orthosteric-model_1.png) |
adenosine A1 receptor
|
Homo sapiens; Human |
AA1R_HUMAN
|
ADORA1 |
P30542
|
CHEMBL226
|
12364 / 14663
|
![](/g/images/s/AA2AR_HUMAN-orthosteric-model_1.png) |
adenosine A2a receptor
|
Homo sapiens; Human |
AA2AR_HUMAN
|
ADORA2A |
P29274
|
CHEMBL251
|
11667 / 13796
|
![](/g/images/s/ACES_HUMAN-orthosteric-model_1.png) |
acetylcholinesterase (Cartwright blood group)
|
Homo sapiens; Human |
ACES_HUMAN
|
ACHE |
P22303
|
CHEMBL220
|
11910 / 14414
|
![](/g/images/s/ACE_HUMAN-orthosteric-model_1.png) |
angiotensin I converting enzyme
|
Homo sapiens; Human |
ACE_HUMAN
|
ACE |
P12821
|
CHEMBL1808
|
1303 / 1342
|
![](/g/images/s/ACHA9_HUMAN-orthosteric-model_1.png) |
cholinergic receptor nicotinic alpha 9 subunit
|
Homo sapiens; Human |
ACHA9_HUMAN
|
CHRNA9 |
Q9UGM1
|
CHEMBL2184
|
1 / 1
|
![](/g/images/s/ACHB2_HUMAN-orthosteric-model_1.png) |
cholinergic receptor nicotinic beta 2 subunit
|
Homo sapiens; Human |
ACHB2_HUMAN
|
CHRNB2 |
P17787
|
CHEMBL1883
|
1 / 1
|
![](/g/images/s/ACM1_HUMAN-orthosteric-model_1.png) |
cholinergic receptor muscarinic 1
|
Homo sapiens; Human |
ACM1_HUMAN
|
CHRM1 |
P11229
|
CHEMBL216
|
6980 / 8900
|
![](/g/images/s/ACM4_HUMAN-orthosteric-model_1.png) |
cholinergic receptor muscarinic 4
|
Homo sapiens; Human |
ACM4_HUMAN
|
CHRM4 |
P08173
|
CHEMBL1821
|
3558 / 5422
|
![](/g/images/s/ADRB2_HUMAN-orthosteric-model_1.png) |
adrenoceptor beta 2
|
Homo sapiens; Human |
ADRB2_HUMAN
|
ADRB2 |
P07550
|
CHEMBL210
|
6371 / 8365
|
![](/g/images/s/AGTR2_HUMAN-orthosteric-model_1.png) |
angiotensin II receptor type 2
|
Homo sapiens; Human |
AGTR2_HUMAN
|
AGTR2 |
P50052
|
CHEMBL4607
|
651 / 2421
|
![](/g/images/s/ALDR_HUMAN-orthosteric-model_1.png) |
aldo-keto reductase family 1 member B
|
Homo sapiens; Human |
ALDR_HUMAN
|
AKR1B1 |
P15121
|
CHEMBL1900
|
1321 / 1331
|
![](/g/images/s/AMPN_HUMAN-orthosteric-model_1.png) |
alanyl aminopeptidase, membrane
|
Homo sapiens; Human |
AMPN_HUMAN
|
ANPEP |
P15144
|
CHEMBL1907
|
758 / 825
|
![](/g/images/s/AOFA_HUMAN-orthosteric-model_1.png) |
monoamine oxidase A
|
Homo sapiens; Human |
AOFA_HUMAN
|
MAOA |
P21397
|
CHEMBL1951
|
6430 / 8557
|
![](/g/images/s/AOFB_HUMAN-orthosteric-model_1.png) |
monoamine oxidase B
|
Homo sapiens; Human |
AOFB_HUMAN
|
MAOB |
P27338
|
CHEMBL2039
|
7134 / 7397
|
![](/g/images/s/BACE1_HUMAN-orthosteric-model_1.png) |
beta-secretase 1
|
Homo sapiens; Human |
BACE1_HUMAN
|
BACE1 |
P56817
|
CHEMBL4822
|
14729 / 14951
|
![](/g/images/s/CAH2_HUMAN-orthosteric-model_1.png) |
carbonic anhydrase 2
|
Homo sapiens; Human |
CAH2_HUMAN
|
CA2 |
P00918
|
CHEMBL205
|
14049 / 15886
|
![](/g/images/s/CASP1_HUMAN-orthosteric-model_1.png) |
caspase 1
|
Homo sapiens; Human |
CASP1_HUMAN
|
CASP1 |
P29466
|
CHEMBL4801
|
4358 / 6156
|
![](/g/images/s/CDK5_HUMAN-orthosteric-model_1.png) |
cyclin dependent kinase 5
|
Homo sapiens; Human |
CDK5_HUMAN
|
CDK5 |
Q00535
|
CHEMBL4036
|
2849 / 2934
|
![](/g/images/s/CHLE_HUMAN-orthosteric-model_1.png) |
butyrylcholinesterase
|
Homo sapiens; Human |
CHLE_HUMAN
|
BCHE |
P06276
|
CHEMBL1914
|
5165 / 5449
|
![](/g/images/s/CNR1_HUMAN-orthosteric-model_1.png) |
cannabinoid receptor 1
|
Homo sapiens; Human |
CNR1_HUMAN
|
CNR1 |
P21554
|
CHEMBL218
|
14060 / 16708
|
![](/g/images/s/CNR2_HUMAN-orthosteric-model_1.png) |
cannabinoid receptor 2
|
Homo sapiens; Human |
CNR2_HUMAN
|
CNR2 |
P34972
|
CHEMBL253
|
14804 / 15481
|
![](/g/images/s/COLI_HUMAN-orthosteric-model_1.png) |
proopiomelanocortin
|
Homo sapiens; Human |
COLI_HUMAN
|
POMC |
P01189
|
|
|
![](/g/images/s/COMT_HUMAN-orthosteric-model_1.png) |
catechol-O-methyltransferase
|
Homo sapiens; Human |
COMT_HUMAN
|
COMT |
P21964
|
CHEMBL2023
|
341 / 345
|
![](/g/images/s/CRP_HUMAN-orthosteric-model_1.png) |
C-reactive protein
|
Homo sapiens; Human |
CRP_HUMAN
|
CRP |
P02741
|
|
|
![](/g/images/s/CXCR1_HUMAN-orthosteric-model_1.png) |
C-X-C motif chemokine receptor 1
|
Homo sapiens; Human |
CXCR1_HUMAN
|
CXCR1 |
P25024
|
CHEMBL4029
|
459 / 2217
|
![](/g/images/s/CXCR4_HUMAN-orthosteric-model_1.png) |
C-X-C motif chemokine receptor 4
|
Homo sapiens; Human |
CXCR4_HUMAN
|
CXCR4 |
P61073
|
CHEMBL2107
|
2874 / 3025
|
![](/g/images/s/DRD2_HUMAN-orthosteric-model_1.png) |
dopamine receptor D2
|
Homo sapiens; Human |
DRD2_HUMAN
|
DRD2 |
P14416
|
CHEMBL217
|
17907 / 20602
|
![](/g/images/s/DRD3_HUMAN-orthosteric-model_1.png) |
dopamine receptor D3
|
Homo sapiens; Human |
DRD3_HUMAN
|
DRD3 |
P35462
|
CHEMBL234
|
9435 / 11350
|
![](/g/images/s/DRD4_HUMAN-orthosteric-model_1.png) |
dopamine receptor D4
|
Homo sapiens; Human |
DRD4_HUMAN
|
DRD4 |
P21917
|
CHEMBL219
|
4850 / 6919
|
![](/g/images/s/EDN1_HUMAN-orthosteric-model_1.png) |
endothelin 1
|
Homo sapiens; Human |
EDN1_HUMAN
|
EDN1 |
P05305
|
|
|
![](/g/images/s/ESR1_HUMAN-orthosteric-model_1.png) |
estrogen receptor 1
|
Homo sapiens; Human |
ESR1_HUMAN
|
ESR1 |
P03372
|
CHEMBL206
|
11495 / 13661
|
![](/g/images/s/FABP5_HUMAN-orthosteric-model_1.png) |
fatty acid binding protein 5
|
Homo sapiens; Human |
FABP5_HUMAN
|
FABP5 |
Q01469
|
CHEMBL3674
|
227 / 228
|
![](/g/images/s/FYN_HUMAN-orthosteric-model_1.png) |
FYN proto-oncogene, Src family tyrosine kinase
|
Homo sapiens; Human |
FYN_HUMAN
|
FYN |
P06241
|
CHEMBL1841
|
3379 / 5142
|
![](/g/images/s/GLRA3_HUMAN-allosteric-model_1.png) |
glycine receptor alpha 3
|
Homo sapiens; Human |
GLRA3_HUMAN
|
GLRA3 |
O75311
|
CHEMBL1075092
|
28 / 44
|
![](/g/images/s/GLRA3_HUMAN-orthosteric-model_1.png) |
glycine receptor alpha 3
|
Homo sapiens; Human |
GLRA3_HUMAN
|
GLRA3 |
O75311
|
CHEMBL1075092
|
28 / 44
|
![](/g/images/s/GRM5_HUMAN-allosteric-model_1.png) |
glutamate metabotropic receptor 5
|
Homo sapiens; Human |
GRM5_HUMAN
|
GRM5 |
P41594
|
CHEMBL3227
|
5553 / 5718
|
![](/g/images/s/HPGDS_HUMAN-orthosteric-model_1.png) |
hematopoietic prostaglandin D synthase
|
Homo sapiens; Human |
HPGDS_HUMAN
|
HPGDS |
O60760
|
CHEMBL5879
|
428 / 443
|
![](/g/images/s/HRH1_HUMAN-orthosteric-model_1.png) |
histamine receptor H1
|
Homo sapiens; Human |
HRH1_HUMAN
|
HRH1 |
P35367
|
CHEMBL231
|
3452 / 5410
|
![](/g/images/s/HYES_HUMAN-orthosteric-model_1.png) |
epoxide hydrolase 2
|
Homo sapiens; Human |
HYES_HUMAN
|
EPHX2 |
P34913
|
CHEMBL2409
|
2943 / 3078
|
![](/g/images/s/IKKB_HUMAN-orthosteric-model_1.png) |
inhibitor of nuclear factor kappa B kinase subunit beta
|
Homo sapiens; Human |
IKKB_HUMAN
|
IKBKB |
O14920
|
CHEMBL1991
|
5308 / 5424
|
![](/g/images/s/MDR1_HUMAN-orthosteric-model_1.png) |
ATP binding cassette subfamily B member 1
|
Homo sapiens; Human |
MDR1_HUMAN
|
ABCB1 |
P08183
|
CHEMBL4302
|
12046 / 12471
|
![](/g/images/s/MIF_HUMAN-orthosteric-model_1.png) |
macrophage migration inhibitory factor
|
Homo sapiens; Human |
MIF_HUMAN
|
MIF |
P14174
|
CHEMBL2085
|
712 / 779
|
![](/g/images/s/MK01_HUMAN-orthosteric-model_1.png) |
mitogen-activated protein kinase 1
|
Homo sapiens; Human |
MK01_HUMAN
|
MAPK1 |
P28482
|
CHEMBL4040
|
21420 / 23200
|
![](/g/images/s/MK03_HUMAN-orthosteric-model_1.png) |
mitogen-activated protein kinase 3
|
Homo sapiens; Human |
MK03_HUMAN
|
MAPK3 |
P27361
|
CHEMBL3385
|
2850 / 4619
|
![](/g/images/s/MTOR_HUMAN-orthosteric-model_1.png) |
mechanistic target of rapamycin kinase
|
Homo sapiens; Human |
MTOR_HUMAN
|
MTOR |
P42345
|
CHEMBL2842
|
12931 / 13105
|
![](/g/images/s/NEP_HUMAN-orthosteric-model_1.png) |
membrane metalloendopeptidase
|
Homo sapiens; Human |
NEP_HUMAN
|
MME |
P08473
|
CHEMBL1944
|
768 / 803
|
![](/g/images/s/NK1R_HUMAN-orthosteric-model_1.png) |
tachykinin receptor 1
|
Homo sapiens; Human |
NK1R_HUMAN
|
TACR1 |
P25103
|
CHEMBL249
|
4191 / 5999
|
![](/g/images/s/NMDE1_HUMAN-orthosteric-model_1.png) |
glutamate ionotropic receptor NMDA type subunit 2A
|
Homo sapiens; Human |
NMDE1_HUMAN
|
GRIN2A |
Q12879
|
CHEMBL1972
|
64 / 64
|
![](/g/images/s/NMDE2_HUMAN-orthosteric-model_1.png) |
glutamate ionotropic receptor NMDA type subunit 2B
|
Homo sapiens; Human |
NMDE2_HUMAN
|
GRIN2B |
Q13224
|
CHEMBL1904
|
378 / 388
|
![](/g/images/s/NMDZ1_HUMAN-orthosteric-model_1.png) |
glutamate ionotropic receptor NMDA type subunit 1
|
Homo sapiens; Human |
NMDZ1_HUMAN
|
GRIN1 |
Q05586
|
CHEMBL2015
|
120 / 120
|
![](/g/images/s/NOS1_HUMAN-orthosteric-model_1.png) |
nitric oxide synthase 1
|
Homo sapiens; Human |
NOS1_HUMAN
|
NOS1 |
P29475
|
CHEMBL3568
|
1652 / 1709
|
![](/g/images/s/NOS2_HUMAN-orthosteric-model_1.png) |
nitric oxide synthase 2
|
Homo sapiens; Human |
NOS2_HUMAN
|
NOS2 |
P35228
|
CHEMBL4481
|
1518 / 1561
|
![](/g/images/s/NTRK1_HUMAN-orthosteric-model_1.png) |
neurotrophic receptor tyrosine kinase 1
|
Homo sapiens; Human |
NTRK1_HUMAN
|
NTRK1 |
P04629
|
CHEMBL2815
|
6670 / 6744
|
![](/g/images/s/OPRD_HUMAN-orthosteric-model_1.png) |
opioid receptor delta 1
|
Homo sapiens; Human |
OPRD_HUMAN
|
OPRD1 |
P41143
|
CHEMBL236
|
10731 / 12871
|
![](/g/images/s/OPRK_HUMAN-orthosteric-model_1.png) |
opioid receptor kappa 1
|
Homo sapiens; Human |
OPRK_HUMAN
|
OPRK1 |
P41145
|
CHEMBL237
|
11463 / 13975
|
![](/g/images/s/OPRM_MOUSE-orthosteric-model_1.png) |
Mu-type opioid receptor
|
Mus musculus; Mouse |
OPRM_MOUSE
|
OPRM1 |
P42866
|
CHEMBL2858
|
1273 / 1305
|
![](/g/images/s/OPRX_HUMAN-orthosteric-model_1.png) |
opioid related nociceptin receptor 1
|
Homo sapiens; Human |
OPRX_HUMAN
|
OPRL1 |
P41146
|
CHEMBL2014
|
3236 / 3473
|
![](/g/images/s/P2RX3_HUMAN-orthosteric-model_1.png) |
purinergic receptor P2X 3
|
Homo sapiens; Human |
P2RX3_HUMAN
|
P2RX3 |
P56373
|
CHEMBL2998
|
1753 / 1766
|
![](/g/images/s/P2Y12_HUMAN-orthosteric-model_1.png) |
purinergic receptor P2Y12
|
Homo sapiens; Human |
P2Y12_HUMAN
|
P2RY12 |
Q9H244
|
CHEMBL2001
|
2182 / 2252
|
![](/g/images/s/PAR1_HUMAN-orthosteric-model_1.png) |
coagulation factor II thrombin receptor
|
Homo sapiens; Human |
PAR1_HUMAN
|
F2R |
P25116
|
CHEMBL3974
|
1685 / 1744
|
![](/g/images/s/PDE4B_HUMAN-orthosteric-model_1.png) |
phosphodiesterase 4B
|
Homo sapiens; Human |
PDE4B_HUMAN
|
PDE4B |
Q07343
|
CHEMBL275
|
2179 / 2250
|
![](/g/images/s/PDE5A_HUMAN-orthosteric-model_1.png) |
phosphodiesterase 5A
|
Homo sapiens; Human |
PDE5A_HUMAN
|
PDE5A |
O76074
|
CHEMBL1827
|
2951 / 4759
|
![](/g/images/s/PERM_HUMAN-orthosteric-model_1.png) |
myeloperoxidase
|
Homo sapiens; Human |
PERM_HUMAN
|
MPO |
P05164
|
CHEMBL2439
|
762 / 857
|
![](/g/images/s/PGH1_SHEEP-orthosteric-model_1.png) |
Prostaglandin G/H synthase 1
|
Ovis aries; Sheep |
PGH1_SHEEP
|
PTGS1 |
P05979
|
CHEMBL2949
|
4535 / 4757
|
![](/g/images/s/PGH2_HUMAN-orthosteric-model_1.png) |
prostaglandin-endoperoxide synthase 2
|
Homo sapiens; Human |
PGH2_HUMAN
|
PTGS2 |
P35354
|
CHEMBL230
|
9578 / 11566
|
![](/g/images/s/PPAP_HUMAN-orthosteric-model_1.png) |
acid phosphatase 3
|
Homo sapiens; Human |
PPAP_HUMAN
|
ACP3 |
P15309
|
CHEMBL2633
|
69 / 69
|
![](/g/images/s/PPARG_HUMAN-orthosteric-model_1.png) |
peroxisome proliferator activated receptor gamma
|
Homo sapiens; Human |
PPARG_HUMAN
|
PPARG |
P37231
|
CHEMBL235
|
12255 / 12983
|
![](/g/images/s/PRGR_HUMAN-orthosteric-model_1.png) |
progesterone receptor
|
Homo sapiens; Human |
PRGR_HUMAN
|
PGR |
P06401
|
CHEMBL208
|
5093 / 5407
|
![](/g/images/s/PTGES_HUMAN-orthosteric-model_1.png) |
prostaglandin E synthase
|
Homo sapiens; Human |
PTGES_HUMAN
|
PTGES |
O14684
|
CHEMBL5658
|
2864 / 3011
|
![](/g/images/s/SC6A4_HUMAN-orthosteric-model_1.png) |
solute carrier family 6 member 4
|
Homo sapiens; Human |
SC6A4_HUMAN
|
SLC6A4 |
P31645
|
CHEMBL228
|
8233 / 10152
|
![](/g/images/s/SCN9A_HUMAN-orthosteric-model_1.png) |
sodium voltage-gated channel alpha subunit 9
|
Homo sapiens; Human |
SCN9A_HUMAN
|
SCN9A |
Q15858
|
CHEMBL4296
|
8109 / 8154
|
![](/g/images/s/TLR4_HUMAN-orthosteric-model_1.png) |
toll like receptor 4
|
Homo sapiens; Human |
TLR4_HUMAN
|
TLR4 |
O00206
|
CHEMBL5255
|
770 / 848
|
![](/g/images/s/TNFA_HUMAN-orthosteric-model_1.png) |
tumor necrosis factor
|
Homo sapiens; Human |
TNFA_HUMAN
|
TNF |
P01375
|
CHEMBL1825
|
1611 / 1704
|
![](/g/images/s/TRBM_HUMAN-orthosteric-model_1.png) |
thrombomodulin
|
Homo sapiens; Human |
TRBM_HUMAN
|
THBD |
P07204
|
|
|
![](/g/images/s/TRPM4_HUMAN-orthosteric-model_1.png) |
transient receptor potential cation channel subfamily M member 4
|
Homo sapiens; Human |
TRPM4_HUMAN
|
TRPM4 |
Q8TD43
|
CHEMBL1628469
|
16 / 16
|
![](/g/images/s/TRPM8_FICAL-orthosteric-model_1.png) |
Uncharacterized protein
|
Ficedula albicollis; Collared flycatcher; Muscicapa albicollis |
TRPM8_FICAL
|
TRPM8 |
U3JD03
|
|
|
![](/g/images/s/TRPV1_RAT-orthosteric-model_1.png) |
Transient receptor potential cation channel subfamily V member 1
|
Rattus norvegicus; Rat |
TRPV1_RAT
|
TRPV1 |
O35433
|
CHEMBL5102
|
2882 / 3263
|
![](/g/images/s/TRPV2_RABIT-orthosteric-model_1.png) |
Transient receptor potential cation channel subfamily V member 2
|
Oryctolagus cuniculus; Rabbit |
TRPV2_RABIT
|
TRPV2 |
G1SNM3
|
|
|
![](/g/images/s/TRPV3_HUMAN-orthosteric-model_1.png) |
transient receptor potential cation channel subfamily V member 3
|
Homo sapiens; Human |
TRPV3_HUMAN
|
TRPV3 |
Q8NET8
|
CHEMBL5522
|
520 / 520
|
![](/g/images/s/TRXR1_HUMAN-orthosteric-model_1.png) |
thioredoxin reductase 1
|
Homo sapiens; Human |
TRXR1_HUMAN
|
TXNRD1 |
Q16881
|
CHEMBL1927
|
51 / 71
|
![](/g/images/s/TRY1_HUMAN-orthosteric-model_1.png) |
serine protease 1
|
Homo sapiens; Human |
TRY1_HUMAN
|
PRSS1 |
P07477
|
CHEMBL209
|
2186 / 2302
|