| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||||
| Icatibant | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.12 | -8.40 | -1.53 | 43.54% | CHEMBL72062 |
| Nefazodone | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.48 | -9.44 | -9.33 | 42.93% | CHEMBL426317 |
| Balsalazide | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.53 | -9.14 | -9.50 | 35.22% | CHEMBL347570 |
| Alfentanil | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -7.92 | -8.19 | -8.21 | 38.51% | CHEMBL148110 |
| Carbamoylcholine | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -4.52 | -4.60 | -4.63 | 31.82% | CHEMBL138958 |
| Icatibant | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | 10.51 | ? | N/A | ? | ? |
| Nefazodone | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -10.28 | -10.03 | N/A | 100.00% | CHEMBL623 |
| Balsalazide | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.16 | -9.40 | N/A | 40.00% | CHEMBL3597649 |
| Alfentanil | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.30 | -7.10 | N/A | 43.15% | CHEMBL4066435 |
| Carbamoylcholine | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -4.36 | -4.47 | N/A | 36.54% | CHEMBL1123 |
| Icatibant | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -5.50 | -10.72 | 6.53 | 44.33% | CHEMBL2337496 |
| Nefazodone | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -9.27 | -9.83 | -10.00 | 51.98% | CHEMBL621 |
| Balsalazide | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -9.11 | -9.33 | -10.11 | 40.77% | CHEMBL473391 |
| Alfentanil | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.27 | -7.80 | -8.56 | 38.29% | CHEMBL1729 |
| Carbamoylcholine | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -4.52 | -4.23 | -4.27 | 36.54% | CHEMBL1123 |
| Icatibant | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -7.78 | -6.15 | N/A | 45.16% | CHEMBL2397891 |
| Nefazodone | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -9.60 | -10.28 | N/A | 51.98% | CHEMBL621 |
| Balsalazide | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -9.13 | -9.02 | N/A | 39.72% | CHEMBL3597636 |
| Alfentanil | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -7.98 | -8.46 | N/A | 38.29% | CHEMBL1729 |
| Carbamoylcholine | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -4.29 | -4.59 | N/A | 36.54% | CHEMBL1123 |
| Icatibant | AA1R_HUMAN | adenosine A1 receptor | ? | ? | ? | ? | ? |
| Nefazodone | AA1R_HUMAN | adenosine A1 receptor | -9.12 | -8.62 | -7.93 | 38.29% | CHEMBL275427 |
| Balsalazide | AA1R_HUMAN | adenosine A1 receptor | -8.57 | -8.59 | -8.04 | 40.82% | CHEMBL371131 |
| Alfentanil | AA1R_HUMAN | adenosine A1 receptor | -7.54 | -7.79 | -7.69 | 33.33% | CHEMBL4065629 |
| Carbamoylcholine | AA1R_HUMAN | adenosine A1 receptor | -3.91 | -3.79 | -4.28 | 15.00% | CHEMBL3350613 |
| Icatibant | AA2AR_HUMAN | adenosine A2a receptor | ? | ? | ? | ? | ? |
| Nefazodone | AA2AR_HUMAN | adenosine A2a receptor | -8.97 | -9.08 | -8.31 | 38.96% | CHEMBL246468 |
| Balsalazide | AA2AR_HUMAN | adenosine A2a receptor | -8.51 | -8.48 | -8.76 | 41.55% | CHEMBL194860 |
| Alfentanil | AA2AR_HUMAN | adenosine A2a receptor | -7.42 | -7.28 | -8.12 | 35.45% | CHEMBL554840 |
| Carbamoylcholine | AA2AR_HUMAN | adenosine A2a receptor | -4.12 | -4.07 | -4.08 | 15.00% | CHEMBL3350613 |
| Icatibant | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | ? | ? | ? | ? | ? |
| Nefazodone | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -10.18 | -9.07 | -9.95 | 34.25% | CHEMBL3632988 |
| Balsalazide | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -8.53 | -8.92 | -7.97 | 43.97% | CHEMBL139353 |
| Alfentanil | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -9.09 | -8.79 | -6.61 | 38.46% | CHEMBL141853 |
| Carbamoylcholine | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -4.64 | -4.45 | -4.81 | 32.69% | CHEMBL366931 |
| Icatibant | ACE_HUMAN | angiotensin I converting enzyme | -8.84 | ? | ? | ? | ? |
| Nefazodone | ACE_HUMAN | angiotensin I converting enzyme | -9.33 | -8.80 | -7.54 | 32.86% | CHEMBL3414814 |
| Balsalazide | ACE_HUMAN | angiotensin I converting enzyme | -8.87 | -8.34 | -8.00 | 41.98% | CHEMBL2112767 |
| Alfentanil | ACE_HUMAN | angiotensin I converting enzyme | -7.98 | -8.77 | -7.54 | 43.88% | CHEMBL78731 |
| Carbamoylcholine | ACE_HUMAN | angiotensin I converting enzyme | -4.46 | -4.33 | -4.29 | 23.53% | CHEMBL78440 |
| Icatibant | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -6.53 | N/A | N/A | 46.90% | CHEMBL386114 |
| Nefazodone | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -5.61 | N/A | N/A | 21.03% | CHEMBL386114 |
| Balsalazide | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -6.99 | N/A | N/A | 27.55% | CHEMBL386114 |
| Alfentanil | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -6.31 | N/A | N/A | 28.44% | CHEMBL386114 |
| Carbamoylcholine | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -3.86 | N/A | N/A | 8.33% | CHEMBL386114 |
| Icatibant | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | ? | ? | ? | N/A | N/A |
| Nefazodone | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -5.53 | -8.51 | -7.66 | N/A | N/A |
| Balsalazide | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -6.75 | -7.22 | -7.58 | N/A | N/A |
| Alfentanil | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -4.74 | -2.82 | -5.23 | N/A | N/A |
| Carbamoylcholine | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -4.89 | -4.76 | -4.47 | N/A | N/A |
| Icatibant | ACM1_HUMAN | cholinergic receptor muscarinic 1 | ? | ? | N/A | ? | ? |
| Nefazodone | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -9.73 | 1.57 | N/A | 37.70% | CHEMBL270580 |
| Balsalazide | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.02 | -0.71 | N/A | 38.46% | CHEMBL3746599 |
| Alfentanil | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.00 | 3.38 | N/A | 49.64% | CHEMBL1243233 |
| Carbamoylcholine | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -4.75 | -4.62 | N/A | 65.52% | CHEMBL667 |
| Icatibant | ACM4_HUMAN | cholinergic receptor muscarinic 4 | ? | ? | N/A | ? | ? |
| Nefazodone | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.79 | -7.78 | N/A | 35.50% | CHEMBL3629360 |
| Balsalazide | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.80 | -8.14 | N/A | 37.70% | CHEMBL1200604 |
| Alfentanil | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -6.95 | -7.64 | N/A | 44.16% | CHEMBL1223804 |
| Carbamoylcholine | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -4.66 | -4.25 | N/A | 100.00% | CHEMBL965 |
| Icatibant | ADRB2_HUMAN | adrenoceptor beta 2 | -5.05 | -3.26 | -1.91 | 42.45% | CHEMBL1814275 |
| Nefazodone | ADRB2_HUMAN | adrenoceptor beta 2 | -8.92 | -9.45 | -9.77 | 42.86% | CHEMBL199824 |
| Balsalazide | ADRB2_HUMAN | adrenoceptor beta 2 | -9.14 | -9.49 | -9.49 | 46.92% | CHEMBL1459608 |
| Alfentanil | ADRB2_HUMAN | adrenoceptor beta 2 | -7.60 | -8.62 | -8.44 | 40.40% | CHEMBL1459608 |
| Carbamoylcholine | ADRB2_HUMAN | adrenoceptor beta 2 | -4.88 | -4.27 | -4.24 | 23.81% | CHEMBL4062049 |
| Icatibant | AGTR2_HUMAN | angiotensin II receptor type 2 | -9.05 | -10.27 | -8.75 | 54.30% | CHEMBL3350599 |
| Nefazodone | AGTR2_HUMAN | angiotensin II receptor type 2 | -9.13 | -9.40 | -8.82 | 33.10% | CHEMBL125760 |
| Balsalazide | AGTR2_HUMAN | angiotensin II receptor type 2 | -8.08 | -8.06 | -7.96 | 36.50% | CHEMBL376286 |
| Alfentanil | AGTR2_HUMAN | angiotensin II receptor type 2 | -7.79 | -8.13 | -7.90 | 34.50% | CHEMBL348157 |
| Carbamoylcholine | AGTR2_HUMAN | angiotensin II receptor type 2 | -3.89 | -4.11 | -3.83 | 14.71% | CHEMBL290829 |
| Icatibant | ALDR_HUMAN | aldo-keto reductase family 1 member B | 0.05 | -4.62 | -5.98 | 41.90% | CHEMBL10382 |
| Nefazodone | ALDR_HUMAN | aldo-keto reductase family 1 member B | -9.04 | -8.72 | -9.15 | 38.07% | CHEMBL143633 |
| Balsalazide | ALDR_HUMAN | aldo-keto reductase family 1 member B | -9.13 | -9.16 | -8.73 | 39.16% | CHEMBL414208 |
| Alfentanil | ALDR_HUMAN | aldo-keto reductase family 1 member B | -8.03 | -7.79 | -7.50 | 34.50% | CHEMBL344057 |
| Carbamoylcholine | ALDR_HUMAN | aldo-keto reductase family 1 member B | -4.86 | -4.80 | -4.89 | 16.47% | CHEMBL436 |
| Icatibant | AMPN_HUMAN | alanyl aminopeptidase, membrane | -9.32 | -9.74 | -9.10 | 62.64% | CHEMBL1077590 |
| Nefazodone | AMPN_HUMAN | alanyl aminopeptidase, membrane | -8.50 | -9.11 | -7.93 | 30.94% | CHEMBL328470 |
| Balsalazide | AMPN_HUMAN | alanyl aminopeptidase, membrane | -8.99 | -8.25 | -8.43 | 30.50% | CHEMBL2204950 |
| Alfentanil | AMPN_HUMAN | alanyl aminopeptidase, membrane | -7.96 | -8.07 | -7.95 | 38.10% | CHEMBL328470 |
| Carbamoylcholine | AMPN_HUMAN | alanyl aminopeptidase, membrane | -4.04 | -4.42 | -4.46 | 26.67% | CHEMBL3298947 |
| Icatibant | AOFA_HUMAN | monoamine oxidase A | 9.00 | ? | ? | ? | ? |
| Nefazodone | AOFA_HUMAN | monoamine oxidase A | -10.56 | -10.20 | -10.22 | 32.98% | CHEMBL4089754 |
| Balsalazide | AOFA_HUMAN | monoamine oxidase A | -9.49 | -9.49 | -10.17 | 40.40% | CHEMBL3407586 |
| Alfentanil | AOFA_HUMAN | monoamine oxidase A | -8.53 | -8.49 | -8.88 | 37.44% | CHEMBL394864 |
| Carbamoylcholine | AOFA_HUMAN | monoamine oxidase A | -4.37 | -4.45 | -4.76 | 23.47% | CHEMBL3780524 |
| Icatibant | AOFB_HUMAN | monoamine oxidase B | ? | ? | ? | ? | ? |
| Nefazodone | AOFB_HUMAN | monoamine oxidase B | -10.38 | -10.43 | -10.28 | 34.87% | CHEMBL4104691 |
| Balsalazide | AOFB_HUMAN | monoamine oxidase B | -9.77 | -10.29 | -9.88 | 42.06% | CHEMBL2426047 |
| Alfentanil | AOFB_HUMAN | monoamine oxidase B | -9.57 | -8.75 | -8.72 | 31.33% | CHEMBL3781329 |
| Carbamoylcholine | AOFB_HUMAN | monoamine oxidase B | -4.49 | -4.56 | -4.57 | 18.68% | CHEMBL3781329 |
| Icatibant | BACE1_HUMAN | beta-secretase 1 | -8.28 | -9.18 | -7.99 | 64.68% | CHEMBL1773545 |
| Nefazodone | BACE1_HUMAN | beta-secretase 1 | -7.51 | -7.56 | -8.13 | 32.46% | CHEMBL3747119 |
| Balsalazide | BACE1_HUMAN | beta-secretase 1 | -6.88 | -7.40 | -8.48 | 41.73% | CHEMBL190644 |
| Alfentanil | BACE1_HUMAN | beta-secretase 1 | -6.77 | -6.97 | -7.51 | 46.43% | CHEMBL1645517 |
| Carbamoylcholine | BACE1_HUMAN | beta-secretase 1 | -3.96 | -4.05 | -3.94 | 19.23% | CHEMBL211256 |
| Icatibant | CAH2_HUMAN | carbonic anhydrase 2 | -7.34 | -8.13 | -4.80 | 49.04% | CHEMBL306510 |
| Nefazodone | CAH2_HUMAN | carbonic anhydrase 2 | -7.94 | -7.85 | -8.02 | 31.84% | CHEMBL4100795 |
| Balsalazide | CAH2_HUMAN | carbonic anhydrase 2 | -7.84 | -8.02 | -7.65 | 47.37% | CHEMBL51534 |
| Alfentanil | CAH2_HUMAN | carbonic anhydrase 2 | -7.34 | -6.93 | -6.84 | 37.67% | CHEMBL183450 |
| Carbamoylcholine | CAH2_HUMAN | carbonic anhydrase 2 | -4.67 | -4.58 | -4.60 | 32.50% | CHEMBL2380745 |
| Icatibant | CASP1_HUMAN | caspase 1 | -7.25 | -7.37 | -6.02 | 51.09% | CHEMBL59362 |
| Nefazodone | CASP1_HUMAN | caspase 1 | -6.17 | -7.86 | -6.81 | 32.55% | CHEMBL26302 |
| Balsalazide | CASP1_HUMAN | caspase 1 | -6.99 | -6.90 | -6.83 | 48.78% | CHEMBL597796 |
| Alfentanil | CASP1_HUMAN | caspase 1 | -5.81 | -6.47 | -5.96 | 42.21% | CHEMBL322631 |
| Carbamoylcholine | CASP1_HUMAN | caspase 1 | -3.58 | -3.77 | -4.28 | 19.80% | CHEMBL430648 |
| Icatibant | CDK5_HUMAN | cyclin dependent kinase 5 | -6.23 | -5.70 | 4.27 | 33.46% | CHEMBL1983111 |
| Nefazodone | CDK5_HUMAN | cyclin dependent kinase 5 | -8.17 | -8.03 | -8.51 | 32.23% | CHEMBL1976040 |
| Balsalazide | CDK5_HUMAN | cyclin dependent kinase 5 | -7.68 | -7.57 | -8.85 | 42.62% | CHEMBL1988141 |
| Alfentanil | CDK5_HUMAN | cyclin dependent kinase 5 | -6.72 | -6.46 | -6.64 | 30.00% | CHEMBL1988141 |
| Carbamoylcholine | CDK5_HUMAN | cyclin dependent kinase 5 | -4.33 | -4.22 | -4.36 | 17.44% | CHEMBL1974288 |
| Icatibant | CHLE_HUMAN | butyrylcholinesterase | ? | ? | ? | ? | ? |
| Nefazodone | CHLE_HUMAN | butyrylcholinesterase | -9.59 | -9.64 | -9.93 | 34.25% | CHEMBL3632988 |
| Balsalazide | CHLE_HUMAN | butyrylcholinesterase | -8.14 | -7.83 | -7.95 | 41.22% | CHEMBL544592 |
| Alfentanil | CHLE_HUMAN | butyrylcholinesterase | -7.91 | -8.44 | -7.94 | 38.06% | CHEMBL4060562 |
| Carbamoylcholine | CHLE_HUMAN | butyrylcholinesterase | -4.28 | -4.36 | -4.60 | 28.41% | CHEMBL480176 |
| Icatibant | CNR1_HUMAN | cannabinoid receptor 1 | -6.75 | -3.75 | -2.86 | 47.46% | CHEMBL562123 |
| Nefazodone | CNR1_HUMAN | cannabinoid receptor 1 | -7.50 | -9.72 | -10.78 | 41.54% | CHEMBL3798331 |
| Balsalazide | CNR1_HUMAN | cannabinoid receptor 1 | -7.93 | -9.62 | -9.18 | 43.61% | CHEMBL1765259 |
| Alfentanil | CNR1_HUMAN | cannabinoid receptor 1 | -7.72 | -9.03 | -8.12 | 39.57% | CHEMBL199873 |
| Carbamoylcholine | CNR1_HUMAN | cannabinoid receptor 1 | -4.73 | -4.83 | -4.54 | 25.00% | CHEMBL175247 |
| Icatibant | CNR2_HUMAN | cannabinoid receptor 2 | ? | ? | N/A | ? | ? |
| Nefazodone | CNR2_HUMAN | cannabinoid receptor 2 | -10.65 | -10.48 | N/A | 37.27% | CHEMBL3092891 |
| Balsalazide | CNR2_HUMAN | cannabinoid receptor 2 | -8.33 | -8.42 | N/A | 43.61% | CHEMBL1765259 |
| Alfentanil | CNR2_HUMAN | cannabinoid receptor 2 | -8.04 | -8.77 | N/A | 39.61% | CHEMBL1762292 |
| Carbamoylcholine | CNR2_HUMAN | cannabinoid receptor 2 | -4.24 | -4.29 | N/A | 24.10% | CHEMBL3597331 |
| Icatibant | COLI_HUMAN | proopiomelanocortin | -8.34 | -7.68 | -7.97 | N/A | N/A |
| Nefazodone | COLI_HUMAN | proopiomelanocortin | -8.91 | -8.41 | -8.76 | N/A | N/A |
| Balsalazide | COLI_HUMAN | proopiomelanocortin | -9.41 | -9.21 | -8.28 | N/A | N/A |
| Alfentanil | COLI_HUMAN | proopiomelanocortin | -7.52 | -7.68 | -6.83 | N/A | N/A |
| Carbamoylcholine | COLI_HUMAN | proopiomelanocortin | -4.46 | -4.59 | -3.75 | N/A | N/A |
| Icatibant | COMT_HUMAN | catechol-O-methyltransferase | ? | ? | ? | ? | ? |
| Nefazodone | COMT_HUMAN | catechol-O-methyltransferase | -6.20 | -6.57 | -6.85 | 29.84% | CHEMBL3954860 |
| Balsalazide | COMT_HUMAN | catechol-O-methyltransferase | -6.29 | -6.11 | -6.44 | 38.40% | CHEMBL3818719 |
| Alfentanil | COMT_HUMAN | catechol-O-methyltransferase | -5.52 | -6.06 | -5.47 | 25.59% | CHEMBL3819488 |
| Carbamoylcholine | COMT_HUMAN | catechol-O-methyltransferase | -3.78 | -3.59 | -4.01 | 11.11% | CHEMBL3425734 |
| Icatibant | CRP_HUMAN | C-reactive protein | -5.22 | 3.30 | N/A | N/A | N/A |
| Nefazodone | CRP_HUMAN | C-reactive protein | -6.16 | -5.51 | N/A | N/A | N/A |
| Balsalazide | CRP_HUMAN | C-reactive protein | -6.39 | -6.59 | N/A | N/A | N/A |
| Alfentanil | CRP_HUMAN | C-reactive protein | -5.35 | -5.48 | N/A | N/A | N/A |
| Carbamoylcholine | CRP_HUMAN | C-reactive protein | -3.56 | -3.64 | N/A | N/A | N/A |
| Icatibant | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | ? | N/A | N/A | ? | ? |
| Nefazodone | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -1.37 | N/A | N/A | 24.02% | CHEMBL376621 |
| Balsalazide | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -3.37 | N/A | N/A | 36.76% | CHEMBL556656 |
| Alfentanil | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -4.35 | N/A | N/A | 29.73% | CHEMBL3701188 |
| Carbamoylcholine | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -5.00 | N/A | N/A | 11.76% | CHEMBL139 |
| Icatibant | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.97 | -8.57 | -7.13 | 64.93% | CHEMBL3894327 |
| Nefazodone | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -9.57 | -7.26 | -8.25 | 28.40% | CHEMBL1256528 |
| Balsalazide | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.32 | -7.86 | -6.91 | 31.85% | CHEMBL2062277 |
| Alfentanil | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.23 | -6.86 | -7.36 | 31.77% | CHEMBL3893083 |
| Carbamoylcholine | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -4.92 | -4.19 | -3.73 | 17.72% | CHEMBL3948266 |
| Icatibant | DRD2_HUMAN | dopamine receptor D2 | -7.15 | N/A | N/A | 50.00% | CHEMBL3647674 |
| Nefazodone | DRD2_HUMAN | dopamine receptor D2 | -9.18 | N/A | N/A | 43.60% | CHEMBL2165134 |
| Balsalazide | DRD2_HUMAN | dopamine receptor D2 | -8.74 | N/A | N/A | 42.15% | CHEMBL3759491 |
| Alfentanil | DRD2_HUMAN | dopamine receptor D2 | -7.37 | N/A | N/A | 45.45% | CHEMBL1242923 |
| Carbamoylcholine | DRD2_HUMAN | dopamine receptor D2 | -4.44 | N/A | N/A | 23.33% | CHEMBL128524 |
| Icatibant | DRD3_HUMAN | dopamine receptor D3 | -3.57 | N/A | N/A | 43.95% | CHEMBL559873 |
| Nefazodone | DRD3_HUMAN | dopamine receptor D3 | -9.01 | N/A | N/A | 42.86% | CHEMBL199824 |
| Balsalazide | DRD3_HUMAN | dopamine receptor D3 | -8.99 | N/A | N/A | 42.15% | CHEMBL3758330 |
| Alfentanil | DRD3_HUMAN | dopamine receptor D3 | -7.42 | N/A | N/A | 40.14% | CHEMBL3354072 |
| Carbamoylcholine | DRD3_HUMAN | dopamine receptor D3 | -4.76 | N/A | N/A | 36.54% | CHEMBL1123 |
| Icatibant | DRD4_HUMAN | dopamine receptor D4 | 4.05 | -5.10 | N/A | 40.52% | CHEMBL1771111 |
| Nefazodone | DRD4_HUMAN | dopamine receptor D4 | -9.99 | -10.10 | N/A | 42.86% | CHEMBL199824 |
| Balsalazide | DRD4_HUMAN | dopamine receptor D4 | -9.25 | -9.12 | N/A | 44.09% | CHEMBL57019 |
| Alfentanil | DRD4_HUMAN | dopamine receptor D4 | -8.52 | -8.60 | N/A | 40.14% | CHEMBL3354072 |
| Carbamoylcholine | DRD4_HUMAN | dopamine receptor D4 | -4.29 | -4.44 | N/A | 23.33% | CHEMBL128524 |
| Icatibant | EDN1_HUMAN | endothelin 1 | -8.79 | N/A | N/A | N/A | N/A |
| Nefazodone | EDN1_HUMAN | endothelin 1 | -8.37 | N/A | N/A | N/A | N/A |
| Balsalazide | EDN1_HUMAN | endothelin 1 | -7.53 | N/A | N/A | N/A | N/A |
| Alfentanil | EDN1_HUMAN | endothelin 1 | -7.78 | N/A | N/A | N/A | N/A |
| Carbamoylcholine | EDN1_HUMAN | endothelin 1 | -3.83 | N/A | N/A | N/A | N/A |
| Icatibant | ESR1_HUMAN | estrogen receptor 1 | -1.21 | -6.91 | -5.63 | 46.34% | CHEMBL241042 |
| Nefazodone | ESR1_HUMAN | estrogen receptor 1 | -9.23 | -8.65 | -7.91 | 35.00% | CHEMBL1462307 |
| Balsalazide | ESR1_HUMAN | estrogen receptor 1 | -8.19 | -7.64 | -6.90 | 39.09% | CHEMBL3645266 |
| Alfentanil | ESR1_HUMAN | estrogen receptor 1 | -7.83 | -7.59 | -7.77 | 36.59% | CHEMBL1475062 |
| Carbamoylcholine | ESR1_HUMAN | estrogen receptor 1 | -4.49 | -4.51 | -4.47 | 26.56% | CHEMBL2165350 |
| Icatibant | FABP5_HUMAN | fatty acid binding protein 5 | 6.33 | -6.84 | -7.01 | 28.16% | CHEMBL3938613 |
| Nefazodone | FABP5_HUMAN | fatty acid binding protein 5 | -9.31 | -5.12 | -5.47 | 24.89% | CHEMBL245284 |
| Balsalazide | FABP5_HUMAN | fatty acid binding protein 5 | -5.73 | -6.23 | -5.86 | 27.27% | CHEMBL3941588 |
| Alfentanil | FABP5_HUMAN | fatty acid binding protein 5 | -8.03 | -5.73 | -5.76 | 29.00% | CHEMBL3959018 |
| Carbamoylcholine | FABP5_HUMAN | fatty acid binding protein 5 | -4.17 | -3.67 | -3.63 | 12.82% | CHEMBL82293 |
| Icatibant | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -8.04 | N/A | N/A | 38.53% | CHEMBL432649 |
| Nefazodone | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -8.53 | N/A | N/A | 33.33% | CHEMBL3824089 |
| Balsalazide | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -8.68 | N/A | N/A | 42.62% | CHEMBL1988141 |
| Alfentanil | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -7.15 | N/A | N/A | 34.56% | CHEMBL407135 |
| Carbamoylcholine | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -3.94 | N/A | N/A | 16.47% | CHEMBL221753 |
| Icatibant | GLRA3_HUMAN | glycine receptor alpha 3 | 12.67 | -2.93 | -7.14 | 25.43% | CHEMBL4070615 |
| Icatibant | GLRA3_HUMAN | glycine receptor alpha 3 | -7.57 | N/A | N/A | 25.43% | CHEMBL4070615 |
| Nefazodone | GLRA3_HUMAN | glycine receptor alpha 3 | -8.49 | -8.25 | -9.18 | 20.28% | CHEMBL4070615 |
| Nefazodone | GLRA3_HUMAN | glycine receptor alpha 3 | -8.57 | N/A | N/A | 20.28% | CHEMBL4070615 |
| Balsalazide | GLRA3_HUMAN | glycine receptor alpha 3 | -7.20 | -7.93 | -7.81 | 18.41% | CHEMBL4070615 |
| Balsalazide | GLRA3_HUMAN | glycine receptor alpha 3 | -8.27 | N/A | N/A | 18.41% | CHEMBL4070615 |
| Alfentanil | GLRA3_HUMAN | glycine receptor alpha 3 | -7.82 | -7.83 | -7.56 | 24.08% | CHEMBL4070615 |
| Alfentanil | GLRA3_HUMAN | glycine receptor alpha 3 | -8.90 | N/A | N/A | 24.08% | CHEMBL4070615 |
| Carbamoylcholine | GLRA3_HUMAN | glycine receptor alpha 3 | -4.27 | -4.51 | -4.55 | 6.44% | CHEMBL4070615 |
| Carbamoylcholine | GLRA3_HUMAN | glycine receptor alpha 3 | -4.45 | N/A | N/A | 6.44% | CHEMBL4070615 |
| Icatibant | GRM5_HUMAN | glutamate metabotropic receptor 5 | ? | ? | ? | ? | ? |
| Nefazodone | GRM5_HUMAN | glutamate metabotropic receptor 5 | -9.31 | -9.38 | -8.53 | 34.75% | CHEMBL3633955 |
| Balsalazide | GRM5_HUMAN | glutamate metabotropic receptor 5 | -9.22 | -7.08 | -7.14 | 42.86% | CHEMBL2151818 |
| Alfentanil | GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.93 | -6.31 | -6.10 | 40.12% | CHEMBL3939327 |
| Carbamoylcholine | GRM5_HUMAN | glutamate metabotropic receptor 5 | -4.64 | -4.66 | -4.61 | 20.00% | CHEMBL1290670 |
| Icatibant | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -6.48 | -8.29 | -6.74 | 44.64% | CHEMBL3903606 |
| Nefazodone | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -8.38 | -9.03 | -7.88 | 34.45% | CHEMBL3650205 |
| Balsalazide | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.86 | -8.36 | -8.61 | 36.59% | CHEMBL2035654 |
| Alfentanil | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -6.76 | -6.72 | -6.86 | 41.52% | CHEMBL3425956 |
| Carbamoylcholine | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -4.17 | -3.66 | -4.08 | 20.99% | CHEMBL2035656 |
| Icatibant | HRH1_HUMAN | histamine receptor H1 | ? | N/A | N/A | ? | ? |
| Nefazodone | HRH1_HUMAN | histamine receptor H1 | -9.49 | N/A | N/A | 51.98% | CHEMBL621 |
| Balsalazide | HRH1_HUMAN | histamine receptor H1 | -9.34 | N/A | N/A | 41.01% | CHEMBL2171024 |
| Alfentanil | HRH1_HUMAN | histamine receptor H1 | -6.43 | N/A | N/A | 45.45% | CHEMBL1242923 |
| Carbamoylcholine | HRH1_HUMAN | histamine receptor H1 | -4.57 | N/A | N/A | 25.51% | CHEMBL481153 |
| Icatibant | HYES_HUMAN | epoxide hydrolase 2 | -9.31 | ? | ? | ? | ? |
| Nefazodone | HYES_HUMAN | epoxide hydrolase 2 | -8.53 | -9.30 | -8.64 | 33.16% | CHEMBL3222131 |
| Balsalazide | HYES_HUMAN | epoxide hydrolase 2 | -9.58 | -8.98 | -8.39 | 43.41% | CHEMBL477046 |
| Alfentanil | HYES_HUMAN | epoxide hydrolase 2 | -7.98 | -7.98 | -8.01 | 42.25% | CHEMBL549576 |
| Carbamoylcholine | HYES_HUMAN | epoxide hydrolase 2 | -4.86 | -4.64 | -4.10 | 25.42% | CHEMBL1818418 |
| Icatibant | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -5.75 | N/A | N/A | 33.46% | CHEMBL372160 |
| Nefazodone | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -8.42 | N/A | N/A | 30.50% | CHEMBL1223063 |
| Balsalazide | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -8.03 | N/A | N/A | 39.24% | CHEMBL514334 |
| Alfentanil | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -5.83 | N/A | N/A | 34.62% | CHEMBL2208034 |
| Carbamoylcholine | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -3.83 | N/A | N/A | 14.42% | CHEMBL507333 |
| Icatibant | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -9.22 | -8.74 | N/A | 49.33% | CHEMBL2074676 |
| Nefazodone | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -8.63 | -8.46 | N/A | 51.98% | CHEMBL621 |
| Balsalazide | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -8.40 | -8.54 | N/A | 44.86% | CHEMBL2074727 |
| Alfentanil | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -7.61 | -7.38 | N/A | 38.46% | CHEMBL1008 |
| Carbamoylcholine | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -4.32 | -4.18 | N/A | 30.16% | CHEMBL1201219 |
| Icatibant | MIF_HUMAN | macrophage migration inhibitory factor | ? | ? | ? | ? | ? |
| Nefazodone | MIF_HUMAN | macrophage migration inhibitory factor | -7.69 | -8.17 | -7.53 | 24.36% | CHEMBL3897449 |
| Balsalazide | MIF_HUMAN | macrophage migration inhibitory factor | -6.53 | -7.52 | -7.23 | 36.76% | CHEMBL1604170 |
| Alfentanil | MIF_HUMAN | macrophage migration inhibitory factor | -6.67 | -6.89 | -5.50 | 23.50% | CHEMBL554271 |
| Carbamoylcholine | MIF_HUMAN | macrophage migration inhibitory factor | -4.30 | -4.50 | -4.16 | 14.56% | CHEMBL1604170 |
| Icatibant | MK01_HUMAN | mitogen-activated protein kinase 1 | -7.10 | -7.34 | 0.49 | 48.62% | CHEMBL3752989 |
| Nefazodone | MK01_HUMAN | mitogen-activated protein kinase 1 | -8.27 | -7.95 | -8.78 | 35.18% | CHEMBL3398598 |
| Balsalazide | MK01_HUMAN | mitogen-activated protein kinase 1 | -8.29 | -7.52 | -6.90 | 38.67% | CHEMBL3799370 |
| Alfentanil | MK01_HUMAN | mitogen-activated protein kinase 1 | -6.36 | -7.08 | -7.23 | 38.67% | CHEMBL3398602 |
| Carbamoylcholine | MK01_HUMAN | mitogen-activated protein kinase 1 | -4.01 | -3.88 | -4.12 | 17.44% | CHEMBL1974288 |
| Icatibant | MK03_HUMAN | mitogen-activated protein kinase 3 | -3.34 | -7.96 | -8.18 | 38.46% | CHEMBL3113587 |
| Nefazodone | MK03_HUMAN | mitogen-activated protein kinase 3 | -9.03 | -9.58 | -8.54 | 29.52% | CHEMBL3590107 |
| Balsalazide | MK03_HUMAN | mitogen-activated protein kinase 3 | -8.21 | -9.14 | -8.11 | 36.81% | CHEMBL3798163 |
| Alfentanil | MK03_HUMAN | mitogen-activated protein kinase 3 | -6.87 | -6.72 | -7.54 | 30.65% | CHEMBL3590107 |
| Carbamoylcholine | MK03_HUMAN | mitogen-activated protein kinase 3 | -4.04 | -3.87 | -4.35 | 16.50% | CHEMBL3113587 |
| Icatibant | MTOR_HUMAN | mechanistic target of rapamycin kinase | -9.10 | -9.08 | -9.54 | 43.85% | CHEMBL4074753 |
| Nefazodone | MTOR_HUMAN | mechanistic target of rapamycin kinase | -9.66 | -10.32 | -10.24 | 38.93% | CHEMBL556947 |
| Balsalazide | MTOR_HUMAN | mechanistic target of rapamycin kinase | -7.77 | -8.85 | -8.01 | 36.26% | CHEMBL3701176 |
| Alfentanil | MTOR_HUMAN | mechanistic target of rapamycin kinase | -9.17 | -8.56 | -8.64 | 40.76% | CHEMBL411735 |
| Carbamoylcholine | MTOR_HUMAN | mechanistic target of rapamycin kinase | -3.83 | -4.19 | -3.80 | 17.28% | CHEMBL3972399 |
| Icatibant | NEP_HUMAN | membrane metalloendopeptidase | -7.35 | -9.04 | -7.44 | 58.67% | CHEMBL198316 |
| Nefazodone | NEP_HUMAN | membrane metalloendopeptidase | -7.55 | -9.43 | -10.14 | 30.13% | CHEMBL50559 |
| Balsalazide | NEP_HUMAN | membrane metalloendopeptidase | -8.61 | -8.13 | -8.84 | 35.21% | CHEMBL3677665 |
| Alfentanil | NEP_HUMAN | membrane metalloendopeptidase | -6.57 | -6.88 | -7.58 | 37.97% | CHEMBL51389 |
| Carbamoylcholine | NEP_HUMAN | membrane metalloendopeptidase | -4.29 | -4.88 | -5.00 | 19.05% | CHEMBL254900 |
| Icatibant | NK1R_HUMAN | tachykinin receptor 1 | -8.96 | -7.03 | -7.82 | 60.10% | CHEMBL1782141 |
| Nefazodone | NK1R_HUMAN | tachykinin receptor 1 | -9.21 | -8.76 | -8.74 | 36.20% | CHEMBL2313630 |
| Balsalazide | NK1R_HUMAN | tachykinin receptor 1 | -7.69 | -8.07 | -7.47 | 38.46% | CHEMBL23928 |
| Alfentanil | NK1R_HUMAN | tachykinin receptor 1 | -8.49 | -7.61 | -7.56 | 45.83% | CHEMBL2313628 |
| Carbamoylcholine | NK1R_HUMAN | tachykinin receptor 1 | -4.07 | -4.04 | -3.64 | 19.81% | CHEMBL136389 |
| Icatibant | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -8.15 | -7.95 | -7.36 | 28.65% | CHEMBL284237 |
| Nefazodone | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -9.47 | -9.57 | -8.65 | 16.90% | CHEMBL2333945 |
| Balsalazide | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -9.59 | -9.65 | -9.47 | 24.06% | CHEMBL284237 |
| Alfentanil | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -7.75 | -6.97 | -7.19 | 13.41% | CHEMBL284237 |
| Carbamoylcholine | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -4.85 | -5.09 | -4.91 | 7.78% | CHEMBL284237 |
| Icatibant | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -8.55 | ? | ? | ? | ? |
| Nefazodone | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -10.24 | -9.61 | -9.15 | 24.58% | CHEMBL48029 |
| Balsalazide | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -8.95 | -9.56 | -9.51 | 35.42% | CHEMBL2013199 |
| Alfentanil | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -8.33 | -9.32 | -6.34 | 30.25% | CHEMBL218017 |
| Carbamoylcholine | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -4.63 | -4.46 | -4.63 | 19.57% | CHEMBL219060 |
| Icatibant | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -8.24 | -7.76 | -7.36 | 41.10% | CHEMBL354003 |
| Nefazodone | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -9.21 | -9.56 | -8.65 | 28.81% | CHEMBL162577 |
| Balsalazide | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -9.70 | -9.81 | -9.47 | 33.33% | CHEMBL163916 |
| Alfentanil | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -7.03 | -7.57 | -7.19 | 28.84% | CHEMBL399075 |
| Carbamoylcholine | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -4.91 | -4.84 | -4.91 | 11.89% | CHEMBL248439 |
| Icatibant | NOS1_HUMAN | nitric oxide synthase 1 | -6.86 | -8.09 | -7.29 | 35.90% | CHEMBL3216543 |
| Nefazodone | NOS1_HUMAN | nitric oxide synthase 1 | -9.34 | -9.55 | -8.98 | 33.33% | CHEMBL3216999 |
| Balsalazide | NOS1_HUMAN | nitric oxide synthase 1 | -9.13 | -9.23 | -8.43 | 37.06% | CHEMBL1221659 |
| Alfentanil | NOS1_HUMAN | nitric oxide synthase 1 | -7.02 | -7.10 | -7.45 | 35.71% | CHEMBL317521 |
| Carbamoylcholine | NOS1_HUMAN | nitric oxide synthase 1 | -4.65 | -4.81 | -4.97 | 24.19% | CHEMBL1956111 |
| Icatibant | NOS2_HUMAN | nitric oxide synthase 2 | ? | ? | ? | ? | ? |
| Nefazodone | NOS2_HUMAN | nitric oxide synthase 2 | -8.28 | -8.91 | -6.21 | 34.02% | CHEMBL440473 |
| Balsalazide | NOS2_HUMAN | nitric oxide synthase 2 | -7.89 | -8.80 | 2.82 | 37.06% | CHEMBL1221659 |
| Alfentanil | NOS2_HUMAN | nitric oxide synthase 2 | -6.38 | -7.35 | -6.15 | 35.62% | CHEMBL112747 |
| Carbamoylcholine | NOS2_HUMAN | nitric oxide synthase 2 | -4.76 | -5.16 | -5.35 | 27.87% | CHEMBL473674 |
| Icatibant | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -6.93 | -6.53 | -7.27 | 34.89% | CHEMBL1258913 |
| Nefazodone | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -8.33 | -9.63 | -9.02 | 36.11% | CHEMBL3915565 |
| Balsalazide | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -8.69 | -8.90 | -8.75 | 42.62% | CHEMBL1988141 |
| Alfentanil | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -7.09 | -7.17 | -7.09 | 35.96% | CHEMBL3934925 |
| Carbamoylcholine | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -3.74 | -4.07 | -3.83 | 17.65% | CHEMBL1984131 |
| Icatibant | OPRD_HUMAN | opioid receptor delta 1 | -7.79 | 27.60 | ? | ? | ? |
| Nefazodone | OPRD_HUMAN | opioid receptor delta 1 | -8.01 | -7.12 | -7.48 | 35.26% | CHEMBL427683 |
| Balsalazide | OPRD_HUMAN | opioid receptor delta 1 | -7.80 | -6.13 | -7.55 | 45.90% | CHEMBL577394 |
| Alfentanil | OPRD_HUMAN | opioid receptor delta 1 | -7.48 | -6.86 | -7.26 | 60.84% | CHEMBL169366 |
| Carbamoylcholine | OPRD_HUMAN | opioid receptor delta 1 | -3.80 | -3.58 | -3.40 | 18.52% | CHEMBL3967052 |
| Icatibant | OPRK_HUMAN | opioid receptor kappa 1 | -8.63 | -9.00 | -6.94 | 61.14% | CHEMBL3808415 |
| Nefazodone | OPRK_HUMAN | opioid receptor kappa 1 | -9.54 | -9.23 | -9.74 | 37.36% | CHEMBL526747 |
| Balsalazide | OPRK_HUMAN | opioid receptor kappa 1 | -8.13 | -8.30 | -8.19 | 41.53% | CHEMBL1257457 |
| Alfentanil | OPRK_HUMAN | opioid receptor kappa 1 | -8.79 | -7.74 | -7.73 | 59.84% | CHEMBL609147 |
| Carbamoylcholine | OPRK_HUMAN | opioid receptor kappa 1 | -3.81 | -4.22 | -4.64 | 24.10% | CHEMBL3219944 |
| Icatibant | OPRM_MOUSE | Mu-type opioid receptor | -8.35 | -8.17 | N/A | 57.75% | CHEMBL330991 |
| Nefazodone | OPRM_MOUSE | Mu-type opioid receptor | -8.16 | -8.42 | N/A | 32.56% | CHEMBL2387736 |
| Balsalazide | OPRM_MOUSE | Mu-type opioid receptor | -7.78 | -7.87 | N/A | 42.37% | CHEMBL2051964 |
| Alfentanil | OPRM_MOUSE | Mu-type opioid receptor | -7.85 | -7.95 | N/A | 54.68% | CHEMBL2311157 |
| Carbamoylcholine | OPRM_MOUSE | Mu-type opioid receptor | -3.89 | -4.15 | N/A | 17.76% | CHEMBL2311157 |
| Icatibant | OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.30 | -8.42 | -8.76 | 60.77% | CHEMBL507269 |
| Nefazodone | OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.00 | -8.05 | -7.71 | 42.58% | CHEMBL260555 |
| Balsalazide | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.58 | -7.19 | -8.06 | 37.60% | CHEMBL233493 |
| Alfentanil | OPRX_HUMAN | opioid related nociceptin receptor 1 | -6.99 | -6.94 | -7.15 | 54.68% | CHEMBL28198 |
| Carbamoylcholine | OPRX_HUMAN | opioid related nociceptin receptor 1 | -3.88 | -3.97 | -4.03 | 21.37% | CHEMBL381287 |
| Icatibant | P2RX3_HUMAN | purinergic receptor P2X 3 | -6.37 | -6.29 | -5.18 | 44.29% | CHEMBL397926 |
| Nefazodone | P2RX3_HUMAN | purinergic receptor P2X 3 | -6.37 | -6.37 | -5.43 | 40.38% | CHEMBL3957828 |
| Balsalazide | P2RX3_HUMAN | purinergic receptor P2X 3 | -6.29 | -5.97 | -5.99 | 38.64% | CHEMBL2376118 |
| Alfentanil | P2RX3_HUMAN | purinergic receptor P2X 3 | -5.65 | -5.35 | -5.29 | 38.89% | CHEMBL3669852 |
| Carbamoylcholine | P2RX3_HUMAN | purinergic receptor P2X 3 | -3.51 | -3.39 | -3.42 | 13.38% | CHEMBL3669852 |
| Icatibant | P2Y12_HUMAN | purinergic receptor P2Y12 | -8.21 | ? | ? | ? | ? |
| Nefazodone | P2Y12_HUMAN | purinergic receptor P2Y12 | -9.34 | -8.67 | -9.59 | 29.88% | CHEMBL3325894 |
| Balsalazide | P2Y12_HUMAN | purinergic receptor P2Y12 | -9.68 | -7.71 | -9.17 | 31.37% | CHEMBL599606 |
| Alfentanil | P2Y12_HUMAN | purinergic receptor P2Y12 | -7.13 | -2.60 | -7.01 | 36.52% | CHEMBL90804 |
| Carbamoylcholine | P2Y12_HUMAN | purinergic receptor P2Y12 | -4.07 | -4.41 | -4.70 | 15.65% | CHEMBL599606 |
| Icatibant | PAR1_HUMAN | coagulation factor II thrombin receptor | -7.51 | N/A | N/A | 54.29% | CHEMBL4065100 |
| Nefazodone | PAR1_HUMAN | coagulation factor II thrombin receptor | -10.17 | N/A | N/A | 31.42% | CHEMBL3704471 |
| Balsalazide | PAR1_HUMAN | coagulation factor II thrombin receptor | -8.51 | N/A | N/A | 38.16% | CHEMBL80623 |
| Alfentanil | PAR1_HUMAN | coagulation factor II thrombin receptor | -5.97 | N/A | N/A | 43.33% | CHEMBL3658403 |
| Carbamoylcholine | PAR1_HUMAN | coagulation factor II thrombin receptor | -4.24 | N/A | N/A | 20.49% | CHEMBL3658412 |
| Icatibant | PDE4B_HUMAN | phosphodiesterase 4B | -7.93 | -9.76 | -2.29 | 36.65% | CHEMBL36318 |
| Nefazodone | PDE4B_HUMAN | phosphodiesterase 4B | -8.83 | -9.49 | -9.49 | 33.33% | CHEMBL3644504 |
| Balsalazide | PDE4B_HUMAN | phosphodiesterase 4B | -9.11 | -8.80 | -8.15 | 38.16% | CHEMBL239299 |
| Alfentanil | PDE4B_HUMAN | phosphodiesterase 4B | -7.59 | -8.23 | -8.17 | 33.53% | CHEMBL239299 |
| Carbamoylcholine | PDE4B_HUMAN | phosphodiesterase 4B | -4.30 | -4.15 | -4.31 | 21.00% | CHEMBL603830 |
| Icatibant | PDE5A_HUMAN | phosphodiesterase 5A | -7.09 | -8.38 | -8.22 | 44.15% | CHEMBL335148 |
| Nefazodone | PDE5A_HUMAN | phosphodiesterase 5A | -8.28 | -9.52 | -8.67 | 41.63% | CHEMBL46621 |
| Balsalazide | PDE5A_HUMAN | phosphodiesterase 5A | -9.37 | -9.27 | -9.14 | 45.68% | CHEMBL35970 |
| Alfentanil | PDE5A_HUMAN | phosphodiesterase 5A | -7.73 | -8.27 | -7.70 | 31.00% | CHEMBL551948 |
| Carbamoylcholine | PDE5A_HUMAN | phosphodiesterase 5A | -4.41 | -4.52 | -4.35 | 14.15% | CHEMBL363889 |
| Icatibant | PERM_HUMAN | myeloperoxidase | -2.08 | 3.65 | -8.10 | 26.21% | CHEMBL3740464 |
| Nefazodone | PERM_HUMAN | myeloperoxidase | -8.05 | -8.32 | -8.02 | 31.92% | CHEMBL2170247 |
| Balsalazide | PERM_HUMAN | myeloperoxidase | -8.09 | -8.43 | -7.78 | 37.98% | CHEMBL86 |
| Alfentanil | PERM_HUMAN | myeloperoxidase | -7.35 | -7.35 | -7.05 | 31.06% | CHEMBL1409565 |
| Carbamoylcholine | PERM_HUMAN | myeloperoxidase | -4.58 | -4.72 | -3.99 | 14.08% | CHEMBL686 |
| Icatibant | PGH1_SHEEP | Prostaglandin G/H synthase 1 | ? | ? | ? | ? | ? |
| Nefazodone | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -8.27 | -9.04 | -8.41 | 28.74% | CHEMBL3331465 |
| Balsalazide | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -8.59 | -8.52 | -9.60 | 42.11% | CHEMBL151441 |
| Alfentanil | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -6.34 | -7.57 | -6.88 | 29.63% | CHEMBL9197 |
| Carbamoylcholine | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -4.27 | -4.31 | -4.30 | 19.59% | CHEMBL3809863 |
| Icatibant | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | ? | ? | ? | ? | ? |
| Nefazodone | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -3.07 | -7.94 | -8.75 | 28.98% | CHEMBL317321 |
| Balsalazide | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -5.17 | -7.65 | -7.97 | 38.28% | CHEMBL122065 |
| Alfentanil | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -3.17 | -4.71 | -6.64 | 31.61% | CHEMBL3809156 |
| Carbamoylcholine | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -4.05 | -4.28 | -4.65 | 22.83% | CHEMBL3808627 |
| Icatibant | PPAP_HUMAN | acid phosphatase 3 | -6.30 | N/A | N/A | 21.11% | CHEMBL501717 |
| Nefazodone | PPAP_HUMAN | acid phosphatase 3 | -8.51 | N/A | N/A | 16.92% | CHEMBL507996 |
| Balsalazide | PPAP_HUMAN | acid phosphatase 3 | -8.79 | N/A | N/A | 24.46% | CHEMBL507996 |
| Alfentanil | PPAP_HUMAN | acid phosphatase 3 | -6.85 | N/A | N/A | 13.45% | CHEMBL507996 |
| Carbamoylcholine | PPAP_HUMAN | acid phosphatase 3 | -4.97 | N/A | N/A | 10.53% | CHEMBL507996 |
| Icatibant | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -8.95 | 5.59 | -7.28 | 42.52% | CHEMBL2208197 |
| Nefazodone | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -8.65 | -10.00 | -8.95 | 40.49% | CHEMBL148639 |
| Balsalazide | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -8.83 | -8.70 | -8.33 | 39.29% | CHEMBL2336644 |
| Alfentanil | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -7.14 | -7.37 | -7.57 | 40.46% | CHEMBL177854 |
| Carbamoylcholine | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -4.29 | -4.36 | -4.35 | 25.00% | CHEMBL3786150 |
| Icatibant | PRGR_HUMAN | progesterone receptor | ? | ? | ? | ? | ? |
| Nefazodone | PRGR_HUMAN | progesterone receptor | -6.69 | -6.03 | -8.97 | 38.02% | CHEMBL552108 |
| Balsalazide | PRGR_HUMAN | progesterone receptor | -3.70 | -4.11 | -6.04 | 33.53% | CHEMBL194812 |
| Alfentanil | PRGR_HUMAN | progesterone receptor | -7.26 | -6.73 | -8.96 | 38.65% | CHEMBL600466 |
| Carbamoylcholine | PRGR_HUMAN | progesterone receptor | -4.32 | -4.28 | -4.99 | 17.31% | CHEMBL500938 |
| Icatibant | PTGES_HUMAN | prostaglandin E synthase | -6.79 | N/A | N/A | 33.21% | CHEMBL3660830 |
| Nefazodone | PTGES_HUMAN | prostaglandin E synthase | -8.01 | N/A | N/A | 33.01% | CHEMBL4078000 |
| Balsalazide | PTGES_HUMAN | prostaglandin E synthase | -8.72 | N/A | N/A | 38.71% | CHEMBL3759709 |
| Alfentanil | PTGES_HUMAN | prostaglandin E synthase | -6.83 | N/A | N/A | 46.75% | CHEMBL3910746 |
| Carbamoylcholine | PTGES_HUMAN | prostaglandin E synthase | -4.30 | N/A | N/A | 14.66% | CHEMBL3926051 |
| Icatibant | SC6A4_HUMAN | solute carrier family 6 member 4 | ? | ? | ? | ? | ? |
| Nefazodone | SC6A4_HUMAN | solute carrier family 6 member 4 | -9.33 | -9.60 | -9.96 | 100.00% | CHEMBL623 |
| Balsalazide | SC6A4_HUMAN | solute carrier family 6 member 4 | -9.39 | -8.82 | -9.49 | 38.81% | CHEMBL245309 |
| Alfentanil | SC6A4_HUMAN | solute carrier family 6 member 4 | -8.85 | -8.71 | -8.89 | 44.97% | CHEMBL91418 |
| Carbamoylcholine | SC6A4_HUMAN | solute carrier family 6 member 4 | -4.45 | -4.38 | -4.53 | 22.22% | CHEMBL900 |
| Icatibant | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -6.62 | N/A | N/A | 49.59% | CHEMBL3416887 |
| Nefazodone | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -8.19 | N/A | N/A | 34.19% | CHEMBL251346 |
| Balsalazide | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.98 | N/A | N/A | 41.84% | CHEMBL3944511 |
| Alfentanil | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -6.44 | N/A | N/A | 36.45% | CHEMBL2296310 |
| Carbamoylcholine | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -4.78 | N/A | N/A | 26.03% | CHEMBL698 |
| Icatibant | TLR4_HUMAN | toll like receptor 4 | -8.58 | -9.51 | -9.11 | 30.87% | CHEMBL382272 |
| Nefazodone | TLR4_HUMAN | toll like receptor 4 | -7.86 | -8.68 | -8.47 | 27.68% | CHEMBL1223752 |
| Balsalazide | TLR4_HUMAN | toll like receptor 4 | -7.08 | -7.34 | -8.16 | 26.67% | CHEMBL1223752 |
| Alfentanil | TLR4_HUMAN | toll like receptor 4 | -7.04 | -7.27 | -7.39 | 35.21% | CHEMBL1223752 |
| Carbamoylcholine | TLR4_HUMAN | toll like receptor 4 | -3.77 | -4.22 | -4.23 | 18.39% | CHEMBL1223752 |
| Icatibant | TNFA_HUMAN | tumor necrosis factor | -7.43 | N/A | N/A | 53.92% | CHEMBL3805016 |
| Nefazodone | TNFA_HUMAN | tumor necrosis factor | -8.18 | N/A | N/A | 34.98% | CHEMBL4110900 |
| Balsalazide | TNFA_HUMAN | tumor necrosis factor | -7.34 | N/A | N/A | 46.85% | CHEMBL114343 |
| Alfentanil | TNFA_HUMAN | tumor necrosis factor | -7.59 | N/A | N/A | 32.28% | CHEMBL3806296 |
| Carbamoylcholine | TNFA_HUMAN | tumor necrosis factor | -4.21 | N/A | N/A | 16.79% | CHEMBL3983488 |
| Icatibant | TRBM_HUMAN | thrombomodulin | -7.53 | -6.63 | N/A | N/A | N/A |
| Nefazodone | TRBM_HUMAN | thrombomodulin | -8.07 | -7.58 | N/A | N/A | N/A |
| Balsalazide | TRBM_HUMAN | thrombomodulin | -8.75 | -7.37 | N/A | N/A | N/A |
| Alfentanil | TRBM_HUMAN | thrombomodulin | -7.35 | -6.98 | N/A | N/A | N/A |
| Carbamoylcholine | TRBM_HUMAN | thrombomodulin | -4.14 | -4.25 | N/A | N/A | N/A |
| Icatibant | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -8.03 | -6.95 | N/A | N/A | N/A |
| Nefazodone | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -7.94 | -7.14 | N/A | N/A | N/A |
| Balsalazide | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -7.48 | -7.64 | N/A | N/A | N/A |
| Alfentanil | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -6.36 | -6.94 | N/A | N/A | N/A |
| Carbamoylcholine | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -4.37 | -4.28 | N/A | N/A | N/A |
| Icatibant | TRPM8_FICAL | Uncharacterized protein | -4.87 | N/A | N/A | N/A | N/A |
| Nefazodone | TRPM8_FICAL | Uncharacterized protein | -10.49 | N/A | N/A | N/A | N/A |
| Balsalazide | TRPM8_FICAL | Uncharacterized protein | -9.20 | N/A | N/A | N/A | N/A |
| Alfentanil | TRPM8_FICAL | Uncharacterized protein | -8.73 | N/A | N/A | N/A | N/A |
| Carbamoylcholine | TRPM8_FICAL | Uncharacterized protein | -4.33 | N/A | N/A | N/A | N/A |
| Icatibant | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -6.96 | N/A | N/A | 49.48% | CHEMBL430173 |
| Nefazodone | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -8.37 | N/A | N/A | 31.92% | CHEMBL3114908 |
| Balsalazide | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -9.23 | N/A | N/A | 39.13% | CHEMBL1779679 |
| Alfentanil | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -7.72 | N/A | N/A | 30.61% | CHEMBL1395445 |
| Carbamoylcholine | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -4.61 | N/A | N/A | 18.10% | CHEMBL2029639 |
| Icatibant | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -9.63 | -6.70 | N/A | N/A | N/A |
| Nefazodone | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -8.13 | -8.46 | N/A | N/A | N/A |
| Balsalazide | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -8.00 | -8.33 | N/A | N/A | N/A |
| Alfentanil | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -6.88 | -7.86 | N/A | N/A | N/A |
| Carbamoylcholine | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -4.81 | -4.71 | N/A | N/A | N/A |
| Icatibant | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -6.54 | -5.30 | N/A | 34.44% | CHEMBL3696387 |
| Nefazodone | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -6.70 | -7.82 | N/A | 25.91% | CHEMBL3664218 |
| Balsalazide | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -6.14 | -7.60 | N/A | 31.79% | CHEMBL3692228 |
| Alfentanil | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -6.96 | -6.64 | N/A | 26.06% | CHEMBL3692258 |
| Carbamoylcholine | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -3.25 | -4.01 | N/A | 18.06% | CHEMBL73188 |
| Icatibant | TRXR1_HUMAN | thioredoxin reductase 1 | -0.91 | -8.73 | -7.95 | N/A | N/A |
| Nefazodone | TRXR1_HUMAN | thioredoxin reductase 1 | -7.82 | -8.03 | -6.36 | N/A | N/A |
| Balsalazide | TRXR1_HUMAN | thioredoxin reductase 1 | -7.16 | -8.84 | -6.61 | N/A | N/A |
| Alfentanil | TRXR1_HUMAN | thioredoxin reductase 1 | -7.66 | -7.69 | -6.21 | N/A | N/A |
| Carbamoylcholine | TRXR1_HUMAN | thioredoxin reductase 1 | -4.57 | -4.84 | -3.64 | N/A | N/A |
| Icatibant | TRY1_HUMAN | serine protease 1 | -6.68 | N/A | N/A | 62.86% | CHEMBL2370424 |
| Nefazodone | TRY1_HUMAN | serine protease 1 | -6.93 | N/A | N/A | 35.16% | CHEMBL2373348 |
| Balsalazide | TRY1_HUMAN | serine protease 1 | -6.83 | N/A | N/A | 54.46% | CHEMBL134268 |
| Alfentanil | TRY1_HUMAN | serine protease 1 | -6.36 | N/A | N/A | 37.11% | CHEMBL421370 |
| Carbamoylcholine | TRY1_HUMAN | serine protease 1 | -4.23 | N/A | N/A | 18.92% | CHEMBL134268 |