| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||||
| Omeprazole | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.53 | -8.57 | -8.98 | 38.51% | CHEMBL190298 |
| Hydrochlorothiazide | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -7.37 | -7.65 | -7.11 | 37.96% | CHEMBL97596 |
| Chlorpropamide | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -7.02 | -7.31 | -7.33 | 38.98% | CHEMBL97596 |
| Oseltamivir | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -6.88 | -6.93 | -7.31 | 28.52% | CHEMBL442 |
| Hydralazine | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -6.96 | -7.24 | -6.77 | 29.41% | CHEMBL39 |
| Omeprazole | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.43 | -8.85 | N/A | 34.19% | CHEMBL343529 |
| Hydrochlorothiazide | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -7.68 | -7.11 | N/A | 41.73% | CHEMBL3753681 |
| Chlorpropamide | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -7.29 | -7.06 | N/A | 53.76% | CHEMBL1471412 |
| Oseltamivir | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -7.42 | -8.06 | N/A | 51.90% | CHEMBL473765 |
| Hydralazine | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -6.66 | -6.60 | N/A | 35.53% | CHEMBL199385 |
| Omeprazole | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.49 | -8.78 | -8.76 | 33.70% | CHEMBL357995 |
| Hydrochlorothiazide | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -6.89 | -7.30 | -7.58 | 34.59% | CHEMBL333784 |
| Chlorpropamide | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -6.76 | -7.01 | -7.32 | 48.08% | CHEMBL333784 |
| Oseltamivir | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -6.58 | -6.85 | -6.77 | 38.05% | CHEMBL1123 |
| Hydralazine | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -7.57 | -7.37 | -7.67 | 35.53% | CHEMBL199385 |
| Omeprazole | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.61 | -8.33 | N/A | 32.97% | CHEMBL3589583 |
| Hydrochlorothiazide | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -6.88 | -7.43 | N/A | 42.64% | CHEMBL1222293 |
| Chlorpropamide | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -6.86 | -7.54 | N/A | 48.08% | CHEMBL333784 |
| Oseltamivir | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -6.99 | -7.71 | N/A | 38.05% | CHEMBL1123 |
| Hydralazine | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -6.93 | -7.12 | N/A | 35.53% | CHEMBL199385 |
| Omeprazole | AA1R_HUMAN | adenosine A1 receptor | -7.69 | -7.91 | -8.26 | 38.16% | CHEMBL125979 |
| Hydrochlorothiazide | AA1R_HUMAN | adenosine A1 receptor | -6.27 | -6.73 | -7.06 | 23.91% | CHEMBL608980 |
| Chlorpropamide | AA1R_HUMAN | adenosine A1 receptor | -6.94 | -6.76 | -7.13 | 28.83% | CHEMBL209230 |
| Oseltamivir | AA1R_HUMAN | adenosine A1 receptor | -7.13 | -6.88 | -6.86 | 33.02% | CHEMBL608220 |
| Hydralazine | AA1R_HUMAN | adenosine A1 receptor | -6.14 | -6.56 | -7.10 | 34.31% | CHEMBL320805 |
| Omeprazole | AA2AR_HUMAN | adenosine A2a receptor | -7.86 | -7.78 | -8.43 | 38.16% | CHEMBL125979 |
| Hydrochlorothiazide | AA2AR_HUMAN | adenosine A2a receptor | -6.53 | -6.43 | -7.08 | 29.44% | CHEMBL483487 |
| Chlorpropamide | AA2AR_HUMAN | adenosine A2a receptor | -6.77 | -6.58 | -6.99 | 29.21% | CHEMBL482436 |
| Oseltamivir | AA2AR_HUMAN | adenosine A2a receptor | -6.49 | -6.90 | -7.69 | 32.97% | CHEMBL3350613 |
| Hydralazine | AA2AR_HUMAN | adenosine A2a receptor | -6.28 | -6.67 | -7.05 | 34.31% | CHEMBL320805 |
| Omeprazole | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -9.48 | -8.83 | -9.58 | 35.53% | CHEMBL374729 |
| Hydrochlorothiazide | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -8.39 | -8.40 | -9.31 | 37.50% | CHEMBL573102 |
| Chlorpropamide | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -8.65 | -7.60 | -8.15 | 55.56% | CHEMBL573102 |
| Oseltamivir | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -7.98 | -7.76 | -8.43 | 43.06% | CHEMBL1080631 |
| Hydralazine | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -7.56 | -7.35 | -8.20 | 41.67% | CHEMBL1202884 |
| Omeprazole | ACE_HUMAN | angiotensin I converting enzyme | -8.51 | -8.76 | -7.09 | 34.00% | CHEMBL3414814 |
| Hydrochlorothiazide | ACE_HUMAN | angiotensin I converting enzyme | -7.42 | -7.19 | -6.82 | 24.87% | CHEMBL514138 |
| Chlorpropamide | ACE_HUMAN | angiotensin I converting enzyme | -7.47 | -7.60 | -6.13 | 29.45% | CHEMBL514138 |
| Oseltamivir | ACE_HUMAN | angiotensin I converting enzyme | -7.17 | -7.02 | -6.23 | 48.03% | CHEMBL1581 |
| Hydralazine | ACE_HUMAN | angiotensin I converting enzyme | -6.50 | -6.65 | -6.46 | 19.18% | CHEMBL3414811 |
| Omeprazole | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -6.73 | N/A | N/A | 19.83% | CHEMBL386114 |
| Hydrochlorothiazide | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -6.63 | N/A | N/A | 14.61% | CHEMBL386114 |
| Chlorpropamide | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -5.63 | N/A | N/A | 15.90% | CHEMBL386114 |
| Oseltamivir | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -5.63 | N/A | N/A | 23.61% | CHEMBL386114 |
| Hydralazine | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -5.94 | N/A | N/A | 12.09% | CHEMBL386114 |
| Omeprazole | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -7.06 | -7.77 | -5.98 | N/A | N/A |
| Hydrochlorothiazide | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -5.17 | -7.39 | -7.13 | N/A | N/A |
| Chlorpropamide | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -7.35 | -7.37 | -7.81 | N/A | N/A |
| Oseltamivir | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -5.80 | -5.54 | -5.97 | N/A | N/A |
| Hydralazine | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -6.39 | -7.02 | -7.20 | N/A | N/A |
| Omeprazole | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.94 | -3.50 | N/A | 34.74% | CHEMBL1935444 |
| Hydrochlorothiazide | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.69 | -4.84 | N/A | 35.00% | CHEMBL2057767 |
| Chlorpropamide | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.51 | -6.98 | N/A | 39.13% | CHEMBL179993 |
| Oseltamivir | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.61 | -6.78 | N/A | 46.92% | CHEMBL182761 |
| Hydralazine | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.12 | -6.85 | N/A | 29.91% | CHEMBL3360955 |
| Omeprazole | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.78 | -8.27 | N/A | 31.58% | CHEMBL59939 |
| Hydrochlorothiazide | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.43 | -6.99 | N/A | 33.74% | CHEMBL4082397 |
| Chlorpropamide | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.68 | -7.00 | N/A | 38.39% | CHEMBL1455766 |
| Oseltamivir | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.64 | -6.90 | N/A | 44.35% | CHEMBL313738 |
| Hydralazine | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.26 | -7.11 | N/A | 25.49% | CHEMBL7568 |
| Omeprazole | ADRB2_HUMAN | adrenoceptor beta 2 | -8.51 | -8.67 | -9.32 | 39.53% | CHEMBL1517798 |
| Hydrochlorothiazide | ADRB2_HUMAN | adrenoceptor beta 2 | -7.04 | -7.49 | -8.28 | 40.14% | CHEMBL1598434 |
| Chlorpropamide | ADRB2_HUMAN | adrenoceptor beta 2 | -6.82 | -7.91 | -7.73 | 47.06% | CHEMBL154906 |
| Oseltamivir | ADRB2_HUMAN | adrenoceptor beta 2 | -6.94 | -7.37 | -7.16 | 37.93% | CHEMBL1569630 |
| Hydralazine | ADRB2_HUMAN | adrenoceptor beta 2 | -7.24 | -7.72 | -7.82 | 32.54% | CHEMBL1383120 |
| Omeprazole | AGTR2_HUMAN | angiotensin II receptor type 2 | -8.16 | -8.80 | -7.80 | 29.82% | CHEMBL2435831 |
| Hydrochlorothiazide | AGTR2_HUMAN | angiotensin II receptor type 2 | -6.90 | -6.76 | -6.38 | 26.13% | CHEMBL194608 |
| Chlorpropamide | AGTR2_HUMAN | angiotensin II receptor type 2 | -7.14 | -6.95 | -7.04 | 33.51% | CHEMBL384462 |
| Oseltamivir | AGTR2_HUMAN | angiotensin II receptor type 2 | -6.78 | -6.89 | -6.29 | 28.32% | CHEMBL3350599 |
| Hydralazine | AGTR2_HUMAN | angiotensin II receptor type 2 | -6.39 | -6.31 | -6.08 | 14.37% | CHEMBL288705 |
| Omeprazole | ALDR_HUMAN | aldo-keto reductase family 1 member B | -8.67 | -8.65 | -9.49 | 29.32% | CHEMBL1917444 |
| Hydrochlorothiazide | ALDR_HUMAN | aldo-keto reductase family 1 member B | -6.87 | -6.82 | -7.00 | 32.69% | CHEMBL240719 |
| Chlorpropamide | ALDR_HUMAN | aldo-keto reductase family 1 member B | -7.68 | -8.22 | -7.94 | 43.70% | CHEMBL19744 |
| Oseltamivir | ALDR_HUMAN | aldo-keto reductase family 1 member B | -6.82 | -7.00 | -7.31 | 31.43% | CHEMBL6944 |
| Hydralazine | ALDR_HUMAN | aldo-keto reductase family 1 member B | -7.98 | -7.98 | -7.62 | 27.84% | CHEMBL369911 |
| Omeprazole | AMPN_HUMAN | alanyl aminopeptidase, membrane | -8.56 | -9.06 | -7.90 | 23.05% | CHEMBL1077591 |
| Hydrochlorothiazide | AMPN_HUMAN | alanyl aminopeptidase, membrane | -7.24 | -7.73 | -7.35 | 21.19% | CHEMBL328470 |
| Chlorpropamide | AMPN_HUMAN | alanyl aminopeptidase, membrane | -7.33 | -7.31 | -7.06 | 28.33% | CHEMBL2332518 |
| Oseltamivir | AMPN_HUMAN | alanyl aminopeptidase, membrane | -6.90 | -7.23 | -6.36 | 33.58% | CHEMBL28650 |
| Hydralazine | AMPN_HUMAN | alanyl aminopeptidase, membrane | -6.65 | -7.46 | -7.26 | 18.26% | CHEMBL328470 |
| Omeprazole | AOFA_HUMAN | monoamine oxidase A | -8.80 | -9.36 | -9.35 | 38.16% | CHEMBL1645554 |
| Hydrochlorothiazide | AOFA_HUMAN | monoamine oxidase A | -7.37 | -7.79 | -7.80 | 23.48% | CHEMBL828 |
| Chlorpropamide | AOFA_HUMAN | monoamine oxidase A | -8.01 | -7.94 | -8.11 | 27.64% | CHEMBL2158242 |
| Oseltamivir | AOFA_HUMAN | monoamine oxidase A | -7.51 | -7.88 | -7.83 | 25.31% | CHEMBL332223 |
| Hydralazine | AOFA_HUMAN | monoamine oxidase A | -7.67 | -7.28 | -8.02 | 30.95% | CHEMBL258420 |
| Omeprazole | AOFB_HUMAN | monoamine oxidase B | -9.38 | -9.39 | -9.31 | 34.59% | CHEMBL1645548 |
| Hydrochlorothiazide | AOFB_HUMAN | monoamine oxidase B | -7.98 | -8.02 | -8.24 | 26.21% | CHEMBL3319259 |
| Chlorpropamide | AOFB_HUMAN | monoamine oxidase B | -7.64 | -8.67 | -7.81 | 29.57% | CHEMBL2158247 |
| Oseltamivir | AOFB_HUMAN | monoamine oxidase B | -7.78 | -7.54 | -7.74 | 34.04% | CHEMBL4062286 |
| Hydralazine | AOFB_HUMAN | monoamine oxidase B | -7.41 | -7.47 | -7.20 | 36.67% | CHEMBL3319272 |
| Omeprazole | BACE1_HUMAN | beta-secretase 1 | -7.11 | -7.19 | -7.93 | 39.49% | CHEMBL1923701 |
| Hydrochlorothiazide | BACE1_HUMAN | beta-secretase 1 | -5.98 | -6.41 | -6.93 | 23.97% | CHEMBL3354257 |
| Chlorpropamide | BACE1_HUMAN | beta-secretase 1 | -5.98 | -5.98 | -6.59 | 32.96% | CHEMBL1097325 |
| Oseltamivir | BACE1_HUMAN | beta-secretase 1 | -5.68 | -6.32 | -6.46 | 43.79% | CHEMBL2047043 |
| Hydralazine | BACE1_HUMAN | beta-secretase 1 | -5.61 | -6.44 | -7.03 | 31.34% | CHEMBL2059101 |
| Omeprazole | CAH2_HUMAN | carbonic anhydrase 2 | -7.24 | -7.81 | -7.60 | 33.48% | CHEMBL3337911 |
| Hydrochlorothiazide | CAH2_HUMAN | carbonic anhydrase 2 | -7.46 | -7.22 | -7.26 | 100.00% | CHEMBL435 |
| Chlorpropamide | CAH2_HUMAN | carbonic anhydrase 2 | -7.10 | -7.07 | -6.94 | 80.23% | CHEMBL3354134 |
| Oseltamivir | CAH2_HUMAN | carbonic anhydrase 2 | -6.64 | -7.20 | -6.89 | 35.44% | CHEMBL2325975 |
| Hydralazine | CAH2_HUMAN | carbonic anhydrase 2 | -6.72 | -6.62 | -6.44 | 31.25% | CHEMBL2336906 |
| Omeprazole | CASP1_HUMAN | caspase 1 | -6.62 | -7.18 | -6.55 | 26.51% | CHEMBL1221690 |
| Hydrochlorothiazide | CASP1_HUMAN | caspase 1 | -5.56 | -5.91 | -6.21 | 27.45% | CHEMBL3133256 |
| Chlorpropamide | CASP1_HUMAN | caspase 1 | -5.94 | -5.88 | -5.68 | 32.19% | CHEMBL422849 |
| Oseltamivir | CASP1_HUMAN | caspase 1 | -5.17 | -6.16 | -5.31 | 45.56% | CHEMBL200819 |
| Hydralazine | CASP1_HUMAN | caspase 1 | -5.92 | -6.75 | -5.72 | 19.40% | CHEMBL1221744 |
| Omeprazole | CDK5_HUMAN | cyclin dependent kinase 5 | -7.77 | -8.00 | -8.29 | 37.50% | CHEMBL2001149 |
| Hydrochlorothiazide | CDK5_HUMAN | cyclin dependent kinase 5 | -7.37 | -7.67 | -7.39 | 34.59% | CHEMBL1967612 |
| Chlorpropamide | CDK5_HUMAN | cyclin dependent kinase 5 | -6.95 | -6.67 | -7.43 | 49.51% | CHEMBL1967612 |
| Oseltamivir | CDK5_HUMAN | cyclin dependent kinase 5 | -6.57 | -6.61 | -6.18 | 28.00% | CHEMBL1967878 |
| Hydralazine | CDK5_HUMAN | cyclin dependent kinase 5 | -6.92 | -7.01 | -7.89 | 50.00% | CHEMBL1971519 |
| Omeprazole | CHLE_HUMAN | butyrylcholinesterase | -9.02 | -8.58 | -8.81 | 31.86% | CHEMBL4063321 |
| Hydrochlorothiazide | CHLE_HUMAN | butyrylcholinesterase | -7.94 | -8.25 | -8.21 | 28.78% | CHEMBL601282 |
| Chlorpropamide | CHLE_HUMAN | butyrylcholinesterase | -7.93 | -7.53 | -7.77 | 35.40% | CHEMBL3918754 |
| Oseltamivir | CHLE_HUMAN | butyrylcholinesterase | -7.52 | -7.32 | -7.80 | 46.46% | CHEMBL504924 |
| Hydralazine | CHLE_HUMAN | butyrylcholinesterase | -7.14 | -7.03 | -7.14 | 41.67% | CHEMBL1202884 |
| Omeprazole | CNR1_HUMAN | cannabinoid receptor 1 | -7.90 | -8.85 | -8.92 | 39.59% | CHEMBL3353833 |
| Hydrochlorothiazide | CNR1_HUMAN | cannabinoid receptor 1 | -5.90 | -7.75 | -7.94 | 44.80% | CHEMBL2336561 |
| Chlorpropamide | CNR1_HUMAN | cannabinoid receptor 1 | -7.16 | -7.41 | -8.12 | 46.73% | CHEMBL445204 |
| Oseltamivir | CNR1_HUMAN | cannabinoid receptor 1 | -5.75 | -7.54 | -7.99 | 47.24% | CHEMBL3597330 |
| Hydralazine | CNR1_HUMAN | cannabinoid receptor 1 | -6.33 | -6.49 | -7.21 | 33.33% | CHEMBL472897 |
| Omeprazole | CNR2_HUMAN | cannabinoid receptor 2 | -8.79 | -8.83 | N/A | 40.64% | CHEMBL3353802 |
| Hydrochlorothiazide | CNR2_HUMAN | cannabinoid receptor 2 | -7.92 | -7.45 | N/A | 44.80% | CHEMBL2336561 |
| Chlorpropamide | CNR2_HUMAN | cannabinoid receptor 2 | -7.98 | -7.74 | N/A | 44.44% | CHEMBL2336561 |
| Oseltamivir | CNR2_HUMAN | cannabinoid receptor 2 | -7.51 | -7.48 | N/A | 46.88% | CHEMBL3597331 |
| Hydralazine | CNR2_HUMAN | cannabinoid receptor 2 | -6.91 | -6.94 | N/A | 32.99% | CHEMBL3421694 |
| Omeprazole | COLI_HUMAN | proopiomelanocortin | -8.63 | -8.57 | -7.96 | N/A | N/A |
| Hydrochlorothiazide | COLI_HUMAN | proopiomelanocortin | -8.08 | -7.31 | -6.75 | N/A | N/A |
| Chlorpropamide | COLI_HUMAN | proopiomelanocortin | -7.51 | -7.30 | -6.37 | N/A | N/A |
| Oseltamivir | COLI_HUMAN | proopiomelanocortin | -6.71 | -6.53 | -5.80 | N/A | N/A |
| Hydralazine | COLI_HUMAN | proopiomelanocortin | -7.22 | -7.17 | -6.43 | N/A | N/A |
| Omeprazole | COMT_HUMAN | catechol-O-methyltransferase | -6.41 | -5.87 | -6.33 | 36.65% | CHEMBL3425721 |
| Hydrochlorothiazide | COMT_HUMAN | catechol-O-methyltransferase | -4.73 | -5.14 | -4.60 | 20.00% | CHEMBL3798524 |
| Chlorpropamide | COMT_HUMAN | catechol-O-methyltransferase | -5.27 | -5.17 | -5.08 | 17.76% | CHEMBL3798524 |
| Oseltamivir | COMT_HUMAN | catechol-O-methyltransferase | -5.08 | -4.86 | -5.25 | 21.15% | CHEMBL3819488 |
| Hydralazine | COMT_HUMAN | catechol-O-methyltransferase | -6.43 | -5.88 | -6.56 | 33.70% | CHEMBL3797305 |
| Omeprazole | CRP_HUMAN | C-reactive protein | -5.71 | -5.65 | N/A | N/A | N/A |
| Hydrochlorothiazide | CRP_HUMAN | C-reactive protein | -5.23 | -5.64 | N/A | N/A | N/A |
| Chlorpropamide | CRP_HUMAN | C-reactive protein | -5.34 | -5.13 | N/A | N/A | N/A |
| Oseltamivir | CRP_HUMAN | C-reactive protein | -4.84 | -5.15 | N/A | N/A | N/A |
| Hydralazine | CRP_HUMAN | C-reactive protein | -5.33 | -6.00 | N/A | N/A | N/A |
| Omeprazole | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -5.36 | N/A | N/A | 36.84% | CHEMBL3426944 |
| Hydrochlorothiazide | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.67 | N/A | N/A | 38.56% | CHEMBL218387 |
| Chlorpropamide | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.75 | N/A | N/A | 35.93% | CHEMBL386072 |
| Oseltamivir | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.08 | N/A | N/A | 24.81% | CHEMBL3701188 |
| Hydralazine | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.72 | N/A | N/A | 26.51% | CHEMBL184637 |
| Omeprazole | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.45 | -6.98 | -7.69 | 33.50% | CHEMBL1644072 |
| Hydrochlorothiazide | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.08 | -6.47 | -6.47 | 27.88% | CHEMBL3627862 |
| Chlorpropamide | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.10 | -6.46 | -6.62 | 28.88% | CHEMBL3627862 |
| Oseltamivir | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -6.59 | -6.15 | -6.30 | 41.12% | CHEMBL1221944 |
| Hydralazine | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.26 | -6.23 | -6.81 | 25.61% | CHEMBL237830 |
| Omeprazole | DRD2_HUMAN | dopamine receptor D2 | -8.31 | N/A | N/A | 37.99% | CHEMBL324619 |
| Hydrochlorothiazide | DRD2_HUMAN | dopamine receptor D2 | -6.78 | N/A | N/A | 38.57% | CHEMBL195247 |
| Chlorpropamide | DRD2_HUMAN | dopamine receptor D2 | -7.61 | N/A | N/A | 40.83% | CHEMBL195247 |
| Oseltamivir | DRD2_HUMAN | dopamine receptor D2 | -6.28 | N/A | N/A | 37.75% | CHEMBL282927 |
| Hydralazine | DRD2_HUMAN | dopamine receptor D2 | -6.49 | N/A | N/A | 35.96% | CHEMBL3221299 |
| Omeprazole | DRD3_HUMAN | dopamine receptor D3 | -8.54 | N/A | N/A | 65.41% | CHEMBL1219 |
| Hydrochlorothiazide | DRD3_HUMAN | dopamine receptor D3 | -7.40 | N/A | N/A | 38.57% | CHEMBL195247 |
| Chlorpropamide | DRD3_HUMAN | dopamine receptor D3 | -6.86 | N/A | N/A | 40.83% | CHEMBL195247 |
| Oseltamivir | DRD3_HUMAN | dopamine receptor D3 | -6.61 | N/A | N/A | 38.05% | CHEMBL1123 |
| Hydralazine | DRD3_HUMAN | dopamine receptor D3 | -6.85 | N/A | N/A | 30.39% | CHEMBL1223748 |
| Omeprazole | DRD4_HUMAN | dopamine receptor D4 | -8.96 | -9.33 | N/A | 35.76% | CHEMBL327782 |
| Hydrochlorothiazide | DRD4_HUMAN | dopamine receptor D4 | -8.06 | -8.13 | N/A | 38.57% | CHEMBL195247 |
| Chlorpropamide | DRD4_HUMAN | dopamine receptor D4 | -7.51 | -7.56 | N/A | 40.83% | CHEMBL195247 |
| Oseltamivir | DRD4_HUMAN | dopamine receptor D4 | -7.11 | -7.12 | N/A | 37.75% | CHEMBL282927 |
| Hydralazine | DRD4_HUMAN | dopamine receptor D4 | -7.51 | -7.67 | N/A | 30.39% | CHEMBL273860 |
| Omeprazole | EDN1_HUMAN | endothelin 1 | -8.38 | N/A | N/A | N/A | N/A |
| Hydrochlorothiazide | EDN1_HUMAN | endothelin 1 | -6.57 | N/A | N/A | N/A | N/A |
| Chlorpropamide | EDN1_HUMAN | endothelin 1 | -7.02 | N/A | N/A | N/A | N/A |
| Oseltamivir | EDN1_HUMAN | endothelin 1 | -6.31 | N/A | N/A | N/A | N/A |
| Hydralazine | EDN1_HUMAN | endothelin 1 | -6.94 | N/A | N/A | N/A | N/A |
| Omeprazole | ESR1_HUMAN | estrogen receptor 1 | -7.50 | -7.51 | -6.95 | 33.51% | CHEMBL1254532 |
| Hydrochlorothiazide | ESR1_HUMAN | estrogen receptor 1 | -7.40 | -7.38 | -7.24 | 39.85% | CHEMBL264655 |
| Chlorpropamide | ESR1_HUMAN | estrogen receptor 1 | -6.78 | -6.71 | -6.77 | 41.23% | CHEMBL264655 |
| Oseltamivir | ESR1_HUMAN | estrogen receptor 1 | -6.75 | -6.99 | -6.99 | 37.80% | CHEMBL241041 |
| Hydralazine | ESR1_HUMAN | estrogen receptor 1 | -7.19 | -6.73 | -6.46 | 34.52% | CHEMBL223026 |
| Omeprazole | FABP5_HUMAN | fatty acid binding protein 5 | -8.12 | -6.02 | -5.77 | 25.31% | CHEMBL247920 |
| Hydrochlorothiazide | FABP5_HUMAN | fatty acid binding protein 5 | -6.94 | -5.70 | -5.65 | 20.32% | CHEMBL3941588 |
| Chlorpropamide | FABP5_HUMAN | fatty acid binding protein 5 | -7.17 | -5.20 | -4.93 | 16.39% | CHEMBL3959018 |
| Oseltamivir | FABP5_HUMAN | fatty acid binding protein 5 | -6.84 | -5.42 | -4.92 | 25.89% | CHEMBL8659 |
| Hydralazine | FABP5_HUMAN | fatty acid binding protein 5 | -6.45 | -5.18 | -5.67 | 17.88% | CHEMBL3941588 |
| Omeprazole | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -8.29 | N/A | N/A | 38.17% | CHEMBL3632717 |
| Hydrochlorothiazide | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -7.17 | N/A | N/A | 31.98% | CHEMBL1993661 |
| Chlorpropamide | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -6.58 | N/A | N/A | 24.57% | CHEMBL1971029 |
| Oseltamivir | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -6.63 | N/A | N/A | 31.62% | CHEMBL407135 |
| Hydralazine | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -6.93 | N/A | N/A | 35.92% | CHEMBL373798 |
| Omeprazole | GLRA3_HUMAN | glycine receptor alpha 3 | -8.64 | -7.72 | -8.51 | 20.97% | CHEMBL4070615 |
| Omeprazole | GLRA3_HUMAN | glycine receptor alpha 3 | -8.43 | N/A | N/A | 20.97% | CHEMBL4070615 |
| Hydrochlorothiazide | GLRA3_HUMAN | glycine receptor alpha 3 | -6.91 | -7.49 | -7.65 | 19.73% | CHEMBL4074873 |
| Hydrochlorothiazide | GLRA3_HUMAN | glycine receptor alpha 3 | -7.54 | N/A | N/A | 19.73% | CHEMBL4074873 |
| Chlorpropamide | GLRA3_HUMAN | glycine receptor alpha 3 | -7.72 | -7.65 | -7.83 | 22.22% | CHEMBL4074873 |
| Chlorpropamide | GLRA3_HUMAN | glycine receptor alpha 3 | -6.94 | N/A | N/A | 22.22% | CHEMBL4074873 |
| Oseltamivir | GLRA3_HUMAN | glycine receptor alpha 3 | -7.16 | -7.59 | -7.32 | 15.83% | CHEMBL4070615 |
| Oseltamivir | GLRA3_HUMAN | glycine receptor alpha 3 | -7.17 | N/A | N/A | 15.83% | CHEMBL4070615 |
| Hydralazine | GLRA3_HUMAN | glycine receptor alpha 3 | -6.97 | -7.21 | -7.12 | 11.79% | CHEMBL4070615 |
| Hydralazine | GLRA3_HUMAN | glycine receptor alpha 3 | -7.67 | N/A | N/A | 11.79% | CHEMBL4070615 |
| Omeprazole | GRM5_HUMAN | glutamate metabotropic receptor 5 | -9.00 | -8.93 | -8.71 | 42.86% | CHEMBL4060880 |
| Hydrochlorothiazide | GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.09 | -6.36 | -6.28 | 30.91% | CHEMBL4097918 |
| Chlorpropamide | GRM5_HUMAN | glutamate metabotropic receptor 5 | -8.47 | -7.28 | -7.20 | 27.50% | CHEMBL1451902 |
| Oseltamivir | GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.04 | -7.72 | -7.56 | 27.69% | CHEMBL3926962 |
| Hydralazine | GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.26 | -7.51 | -7.40 | 34.41% | CHEMBL1682803 |
| Omeprazole | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.47 | -7.98 | -8.36 | 28.50% | CHEMBL3425948 |
| Hydrochlorothiazide | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -6.73 | -6.10 | -7.55 | 22.96% | CHEMBL1490019 |
| Chlorpropamide | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.75 | -5.98 | -6.37 | 20.00% | CHEMBL1490019 |
| Oseltamivir | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.01 | -5.12 | -5.77 | 30.89% | CHEMBL3698260 |
| Hydralazine | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -6.45 | -6.37 | -7.55 | 20.00% | CHEMBL3650196 |
| Omeprazole | HRH1_HUMAN | histamine receptor H1 | -8.51 | N/A | N/A | 38.54% | CHEMBL1935448 |
| Hydrochlorothiazide | HRH1_HUMAN | histamine receptor H1 | -5.64 | N/A | N/A | 43.95% | CHEMBL2171041 |
| Chlorpropamide | HRH1_HUMAN | histamine receptor H1 | -7.31 | N/A | N/A | 58.97% | CHEMBL2171035 |
| Oseltamivir | HRH1_HUMAN | histamine receptor H1 | -6.86 | N/A | N/A | 32.53% | CHEMBL1278020 |
| Hydralazine | HRH1_HUMAN | histamine receptor H1 | -7.79 | N/A | N/A | 27.45% | CHEMBL511 |
| Omeprazole | HYES_HUMAN | epoxide hydrolase 2 | -7.89 | -8.29 | -7.66 | 32.38% | CHEMBL550648 |
| Hydrochlorothiazide | HYES_HUMAN | epoxide hydrolase 2 | -7.69 | -8.28 | -6.68 | 42.11% | CHEMBL2392747 |
| Chlorpropamide | HYES_HUMAN | epoxide hydrolase 2 | -7.05 | -7.59 | -6.54 | 51.52% | CHEMBL438838 |
| Oseltamivir | HYES_HUMAN | epoxide hydrolase 2 | -6.99 | -7.00 | -7.08 | 47.90% | CHEMBL561665 |
| Hydralazine | HYES_HUMAN | epoxide hydrolase 2 | -7.34 | -7.19 | -6.84 | 24.69% | CHEMBL2031937 |
| Omeprazole | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -8.11 | N/A | N/A | 35.03% | CHEMBL482769 |
| Hydrochlorothiazide | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -7.14 | N/A | N/A | 33.73% | CHEMBL411659 |
| Chlorpropamide | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -6.52 | N/A | N/A | 35.71% | CHEMBL230488 |
| Oseltamivir | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -6.89 | N/A | N/A | 43.26% | CHEMBL1672879 |
| Hydralazine | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -7.23 | N/A | N/A | 36.36% | CHEMBL390201 |
| Omeprazole | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -7.91 | -7.57 | N/A | 33.33% | CHEMBL343002 |
| Hydrochlorothiazide | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -6.89 | -7.02 | N/A | 50.93% | CHEMBL498 |
| Chlorpropamide | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -6.36 | -6.33 | N/A | 100.00% | CHEMBL498 |
| Oseltamivir | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -6.71 | -6.38 | N/A | 55.76% | CHEMBL2075043 |
| Hydralazine | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -6.79 | -7.23 | N/A | 29.09% | CHEMBL2391709 |
| Omeprazole | MIF_HUMAN | macrophage migration inhibitory factor | -7.00 | -6.76 | -6.67 | 30.48% | CHEMBL3924400 |
| Hydrochlorothiazide | MIF_HUMAN | macrophage migration inhibitory factor | -4.93 | -5.56 | -4.98 | 23.53% | CHEMBL3409229 |
| Chlorpropamide | MIF_HUMAN | macrophage migration inhibitory factor | -6.18 | -7.48 | -7.06 | 34.07% | CHEMBL3409229 |
| Oseltamivir | MIF_HUMAN | macrophage migration inhibitory factor | -5.81 | -5.99 | -5.73 | 31.69% | CHEMBL2375653 |
| Hydralazine | MIF_HUMAN | macrophage migration inhibitory factor | -5.72 | -6.79 | -5.41 | 33.75% | CHEMBL224086 |
| Omeprazole | MK01_HUMAN | mitogen-activated protein kinase 1 | -7.74 | -7.55 | -7.32 | 30.38% | CHEMBL4110942 |
| Hydrochlorothiazide | MK01_HUMAN | mitogen-activated protein kinase 1 | -6.78 | -6.55 | -6.04 | 31.98% | CHEMBL1993661 |
| Chlorpropamide | MK01_HUMAN | mitogen-activated protein kinase 1 | -6.74 | -6.74 | -7.01 | 27.61% | CHEMBL1987756 |
| Oseltamivir | MK01_HUMAN | mitogen-activated protein kinase 1 | -6.20 | -6.44 | -6.50 | 30.77% | CHEMBL3752989 |
| Hydralazine | MK01_HUMAN | mitogen-activated protein kinase 1 | -6.53 | -7.05 | -7.13 | 34.29% | CHEMBL86754 |
| Omeprazole | MK03_HUMAN | mitogen-activated protein kinase 3 | -8.41 | -8.54 | -8.11 | 29.08% | CHEMBL1336 |
| Hydrochlorothiazide | MK03_HUMAN | mitogen-activated protein kinase 3 | -7.87 | -6.98 | -6.81 | 20.86% | CHEMBL3799716 |
| Chlorpropamide | MK03_HUMAN | mitogen-activated protein kinase 3 | -7.01 | -7.19 | -6.52 | 24.67% | CHEMBL3798692 |
| Oseltamivir | MK03_HUMAN | mitogen-activated protein kinase 3 | -6.48 | -7.02 | -6.04 | 27.33% | CHEMBL3113587 |
| Hydralazine | MK03_HUMAN | mitogen-activated protein kinase 3 | -6.76 | -6.75 | -6.85 | 28.70% | CHEMBL3798109 |
| Omeprazole | MTOR_HUMAN | mechanistic target of rapamycin kinase | -8.15 | -8.11 | -8.14 | 34.15% | CHEMBL2030445 |
| Hydrochlorothiazide | MTOR_HUMAN | mechanistic target of rapamycin kinase | -6.83 | -6.86 | -7.01 | 33.85% | CHEMBL4059778 |
| Chlorpropamide | MTOR_HUMAN | mechanistic target of rapamycin kinase | -7.30 | -7.60 | -7.15 | 29.61% | CHEMBL4059778 |
| Oseltamivir | MTOR_HUMAN | mechanistic target of rapamycin kinase | -6.84 | -7.36 | -6.89 | 50.00% | CHEMBL269732 |
| Hydralazine | MTOR_HUMAN | mechanistic target of rapamycin kinase | -6.74 | -6.88 | -6.89 | 26.50% | CHEMBL1762778 |
| Omeprazole | NEP_HUMAN | membrane metalloendopeptidase | -8.03 | -7.43 | -8.31 | 26.34% | CHEMBL305388 |
| Hydrochlorothiazide | NEP_HUMAN | membrane metalloendopeptidase | -7.96 | -6.61 | -6.81 | 20.40% | CHEMBL298388 |
| Chlorpropamide | NEP_HUMAN | membrane metalloendopeptidase | -7.10 | -7.72 | -7.92 | 24.17% | CHEMBL225085 |
| Oseltamivir | NEP_HUMAN | membrane metalloendopeptidase | -6.66 | -6.51 | -7.47 | 36.72% | CHEMBL434492 |
| Hydralazine | NEP_HUMAN | membrane metalloendopeptidase | -6.77 | -6.81 | -6.68 | 23.77% | CHEMBL211943 |
| Omeprazole | NK1R_HUMAN | tachykinin receptor 1 | -8.09 | -8.50 | -7.37 | 29.49% | CHEMBL43970 |
| Hydrochlorothiazide | NK1R_HUMAN | tachykinin receptor 1 | -6.79 | -7.54 | -6.59 | 27.27% | CHEMBL345866 |
| Chlorpropamide | NK1R_HUMAN | tachykinin receptor 1 | -6.84 | -7.01 | -6.36 | 29.34% | CHEMBL33194 |
| Oseltamivir | NK1R_HUMAN | tachykinin receptor 1 | -7.16 | -7.04 | -6.44 | 43.28% | CHEMBL1090437 |
| Hydralazine | NK1R_HUMAN | tachykinin receptor 1 | -6.78 | -6.97 | -6.72 | 21.78% | CHEMBL383289 |
| Omeprazole | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -8.91 | -8.39 | -9.15 | 16.42% | CHEMBL2333945 |
| Hydrochlorothiazide | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -7.05 | -8.07 | -7.33 | 28.29% | CHEMBL2333945 |
| Chlorpropamide | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -8.16 | -7.24 | -7.75 | 39.34% | CHEMBL2333945 |
| Oseltamivir | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -7.49 | -7.19 | -6.80 | 11.66% | CHEMBL284237 |
| Hydralazine | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -7.54 | -7.32 | -7.71 | 9.63% | CHEMBL2333945 |
| Omeprazole | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -8.97 | -9.36 | -8.30 | 38.65% | CHEMBL2013202 |
| Hydrochlorothiazide | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -7.16 | -7.27 | -7.27 | 16.13% | CHEMBL1779013 |
| Chlorpropamide | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -8.21 | -7.86 | -7.14 | 23.30% | CHEMBL159879 |
| Oseltamivir | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -7.70 | -7.87 | -7.45 | 21.02% | CHEMBL218547 |
| Hydralazine | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -7.23 | -6.73 | -7.86 | 22.81% | CHEMBL2013202 |
| Omeprazole | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -9.21 | -8.49 | -9.15 | 29.57% | CHEMBL162577 |
| Hydrochlorothiazide | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -7.41 | -7.07 | -7.33 | 33.52% | CHEMBL159739 |
| Chlorpropamide | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -8.18 | -7.20 | -7.75 | 38.85% | CHEMBL159739 |
| Oseltamivir | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -7.42 | -7.09 | -6.80 | 22.94% | CHEMBL354003 |
| Hydralazine | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -7.54 | -7.24 | -7.71 | 16.31% | CHEMBL164231 |
| Omeprazole | NOS1_HUMAN | nitric oxide synthase 1 | -8.15 | -8.01 | -8.65 | 46.62% | CHEMBL1800523 |
| Hydrochlorothiazide | NOS1_HUMAN | nitric oxide synthase 1 | -7.72 | -8.03 | -7.58 | 25.21% | CHEMBL469352 |
| Chlorpropamide | NOS1_HUMAN | nitric oxide synthase 1 | -7.41 | -7.60 | -7.38 | 23.58% | CHEMBL256069 |
| Oseltamivir | NOS1_HUMAN | nitric oxide synthase 1 | -7.25 | -7.40 | -7.55 | 33.99% | CHEMBL317521 |
| Hydralazine | NOS1_HUMAN | nitric oxide synthase 1 | -7.45 | -7.68 | -6.80 | 36.67% | CHEMBL479014 |
| Omeprazole | NOS2_HUMAN | nitric oxide synthase 2 | -7.69 | -8.19 | -7.78 | 60.00% | CHEMBL1800348 |
| Hydrochlorothiazide | NOS2_HUMAN | nitric oxide synthase 2 | -7.71 | -7.41 | -7.85 | 27.41% | CHEMBL490886 |
| Chlorpropamide | NOS2_HUMAN | nitric oxide synthase 2 | -7.42 | -7.25 | -7.74 | 37.38% | CHEMBL490886 |
| Oseltamivir | NOS2_HUMAN | nitric oxide synthase 2 | -7.37 | -7.11 | -7.14 | 30.16% | CHEMBL195352 |
| Hydralazine | NOS2_HUMAN | nitric oxide synthase 2 | -6.64 | -6.56 | -6.87 | 36.67% | CHEMBL479014 |
| Omeprazole | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -8.00 | -8.47 | -8.32 | 32.88% | CHEMBL3666424 |
| Hydrochlorothiazide | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -6.85 | -7.03 | -7.09 | 34.38% | CHEMBL1996795 |
| Chlorpropamide | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -6.83 | -7.11 | -6.82 | 31.94% | CHEMBL1996795 |
| Oseltamivir | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -6.53 | -6.40 | -6.80 | 25.94% | CHEMBL416056 |
| Hydralazine | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -7.21 | -7.67 | -7.73 | 50.00% | CHEMBL1971519 |
| Omeprazole | OPRD_HUMAN | opioid receptor delta 1 | -7.10 | -6.40 | -6.84 | 31.10% | CHEMBL420863 |
| Hydrochlorothiazide | OPRD_HUMAN | opioid receptor delta 1 | -6.18 | -6.09 | -6.46 | 25.93% | CHEMBL339621 |
| Chlorpropamide | OPRD_HUMAN | opioid receptor delta 1 | -6.48 | -5.62 | -5.91 | 38.10% | CHEMBL339621 |
| Oseltamivir | OPRD_HUMAN | opioid receptor delta 1 | -6.35 | -5.85 | -6.10 | 39.57% | CHEMBL1743604 |
| Hydralazine | OPRD_HUMAN | opioid receptor delta 1 | -6.92 | -5.75 | -6.31 | 29.69% | CHEMBL3185265 |
| Omeprazole | OPRK_HUMAN | opioid receptor kappa 1 | -8.77 | -8.26 | -8.32 | 34.23% | CHEMBL1703196 |
| Hydrochlorothiazide | OPRK_HUMAN | opioid receptor kappa 1 | -7.17 | -6.78 | -6.68 | 39.74% | CHEMBL499352 |
| Chlorpropamide | OPRK_HUMAN | opioid receptor kappa 1 | -7.43 | -7.46 | -7.22 | 40.91% | CHEMBL499352 |
| Oseltamivir | OPRK_HUMAN | opioid receptor kappa 1 | -7.38 | -7.52 | -6.34 | 44.62% | CHEMBL3219944 |
| Hydralazine | OPRK_HUMAN | opioid receptor kappa 1 | -6.61 | -6.60 | -7.20 | 31.40% | CHEMBL4101810 |
| Omeprazole | OPRM_MOUSE | Mu-type opioid receptor | -8.00 | -7.78 | N/A | 30.41% | CHEMBL2147918 |
| Hydrochlorothiazide | OPRM_MOUSE | Mu-type opioid receptor | -6.55 | -7.11 | N/A | 17.39% | CHEMBL596 |
| Chlorpropamide | OPRM_MOUSE | Mu-type opioid receptor | -7.47 | -6.94 | N/A | 25.00% | CHEMBL2311130 |
| Oseltamivir | OPRM_MOUSE | Mu-type opioid receptor | -6.31 | -6.61 | N/A | 46.40% | CHEMBL2057689 |
| Hydralazine | OPRM_MOUSE | Mu-type opioid receptor | -7.20 | -6.38 | N/A | 18.38% | CHEMBL327745 |
| Omeprazole | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.21 | -7.26 | -7.45 | 39.78% | CHEMBL407068 |
| Hydrochlorothiazide | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.01 | -6.34 | -6.74 | 33.09% | CHEMBL3942616 |
| Chlorpropamide | OPRX_HUMAN | opioid related nociceptin receptor 1 | -6.24 | -6.17 | -6.18 | 46.79% | CHEMBL3942616 |
| Oseltamivir | OPRX_HUMAN | opioid related nociceptin receptor 1 | -6.22 | -5.95 | -6.41 | 32.93% | CHEMBL1783822 |
| Hydralazine | OPRX_HUMAN | opioid related nociceptin receptor 1 | -6.05 | -6.41 | -6.34 | 26.88% | CHEMBL3139682 |
| Omeprazole | P2RX3_HUMAN | purinergic receptor P2X 3 | -5.88 | -5.82 | -6.22 | 30.05% | CHEMBL3091607 |
| Hydrochlorothiazide | P2RX3_HUMAN | purinergic receptor P2X 3 | -5.78 | -5.94 | -5.34 | 27.49% | CHEMBL413145 |
| Chlorpropamide | P2RX3_HUMAN | purinergic receptor P2X 3 | -5.66 | -5.02 | -5.17 | 24.68% | CHEMBL3901056 |
| Oseltamivir | P2RX3_HUMAN | purinergic receptor P2X 3 | -5.17 | -4.60 | -5.04 | 35.16% | CHEMBL3669852 |
| Hydralazine | P2RX3_HUMAN | purinergic receptor P2X 3 | -5.51 | -5.16 | -5.58 | 22.41% | CHEMBL3897696 |
| Omeprazole | P2Y12_HUMAN | purinergic receptor P2Y12 | -8.63 | -8.94 | -9.34 | 30.61% | CHEMBL2419492 |
| Hydrochlorothiazide | P2Y12_HUMAN | purinergic receptor P2Y12 | -7.60 | -7.36 | -8.32 | 37.10% | CHEMBL2402253 |
| Chlorpropamide | P2Y12_HUMAN | purinergic receptor P2Y12 | -7.70 | -7.42 | -8.01 | 38.75% | CHEMBL2402155 |
| Oseltamivir | P2Y12_HUMAN | purinergic receptor P2Y12 | -6.92 | -5.69 | -6.72 | 30.11% | CHEMBL88444 |
| Hydralazine | P2Y12_HUMAN | purinergic receptor P2Y12 | -7.08 | -7.29 | -7.77 | 25.00% | CHEMBL90195 |
| Omeprazole | PAR1_HUMAN | coagulation factor II thrombin receptor | -9.83 | N/A | N/A | 29.74% | CHEMBL207791 |
| Hydrochlorothiazide | PAR1_HUMAN | coagulation factor II thrombin receptor | -7.41 | N/A | N/A | 24.59% | CHEMBL3143297 |
| Chlorpropamide | PAR1_HUMAN | coagulation factor II thrombin receptor | -7.62 | N/A | N/A | 25.71% | CHEMBL313645 |
| Oseltamivir | PAR1_HUMAN | coagulation factor II thrombin receptor | -7.85 | N/A | N/A | 38.46% | CHEMBL3892331 |
| Hydralazine | PAR1_HUMAN | coagulation factor II thrombin receptor | -7.02 | N/A | N/A | 26.26% | CHEMBL292089 |
| Omeprazole | PDE4B_HUMAN | phosphodiesterase 4B | -8.21 | -8.84 | -8.62 | 35.88% | CHEMBL1224653 |
| Hydrochlorothiazide | PDE4B_HUMAN | phosphodiesterase 4B | -7.29 | -6.94 | -7.09 | 31.29% | CHEMBL576479 |
| Chlorpropamide | PDE4B_HUMAN | phosphodiesterase 4B | -7.07 | -7.24 | -7.21 | 28.19% | CHEMBL517590 |
| Oseltamivir | PDE4B_HUMAN | phosphodiesterase 4B | -7.38 | -6.62 | -6.92 | 30.56% | CHEMBL451500 |
| Hydralazine | PDE4B_HUMAN | phosphodiesterase 4B | -6.96 | -7.97 | -7.73 | 50.00% | CHEMBL124706 |
| Omeprazole | PDE5A_HUMAN | phosphodiesterase 5A | -7.72 | -8.34 | -8.07 | 34.73% | CHEMBL43795 |
| Hydrochlorothiazide | PDE5A_HUMAN | phosphodiesterase 5A | -7.07 | -7.63 | -7.55 | 24.88% | CHEMBL2414309 |
| Chlorpropamide | PDE5A_HUMAN | phosphodiesterase 5A | -6.66 | -7.24 | -6.67 | 25.64% | CHEMBL146373 |
| Oseltamivir | PDE5A_HUMAN | phosphodiesterase 5A | -6.55 | -7.19 | -6.35 | 28.19% | CHEMBL190364 |
| Hydralazine | PDE5A_HUMAN | phosphodiesterase 5A | -7.65 | -6.94 | -6.98 | 36.70% | CHEMBL332898 |
| Omeprazole | PERM_HUMAN | myeloperoxidase | -8.19 | -7.97 | -7.41 | 32.53% | CHEMBL581893 |
| Hydrochlorothiazide | PERM_HUMAN | myeloperoxidase | -6.38 | -6.97 | -6.38 | 21.67% | CHEMBL3741401 |
| Chlorpropamide | PERM_HUMAN | myeloperoxidase | -7.43 | -7.74 | -7.54 | 24.36% | CHEMBL3741401 |
| Oseltamivir | PERM_HUMAN | myeloperoxidase | -6.67 | -6.80 | -6.70 | 19.88% | CHEMBL490 |
| Hydralazine | PERM_HUMAN | myeloperoxidase | -7.96 | -8.08 | -7.81 | 100.00% | CHEMBL276832 |
| Omeprazole | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -8.01 | -8.64 | -8.81 | 33.33% | CHEMBL438316 |
| Hydrochlorothiazide | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -6.17 | -7.71 | -6.50 | 25.13% | CHEMBL280636 |
| Chlorpropamide | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -7.37 | -7.29 | -7.40 | 27.42% | CHEMBL2041695 |
| Oseltamivir | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -6.31 | -7.01 | -7.02 | 45.52% | CHEMBL500387 |
| Hydralazine | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -6.97 | -7.13 | -6.70 | 21.59% | CHEMBL104592 |
| Omeprazole | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -4.98 | -6.02 | -7.45 | 32.18% | CHEMBL1950010 |
| Hydrochlorothiazide | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -6.25 | -6.61 | -6.78 | 36.92% | CHEMBL52872 |
| Chlorpropamide | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -6.57 | -6.85 | -7.55 | 40.82% | CHEMBL52820 |
| Oseltamivir | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -5.23 | -5.89 | -7.70 | 42.86% | CHEMBL463763 |
| Hydralazine | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -7.61 | -7.27 | -7.08 | 28.09% | CHEMBL347198 |
| Omeprazole | PPAP_HUMAN | acid phosphatase 3 | -7.62 | N/A | N/A | 17.03% | CHEMBL507996 |
| Hydrochlorothiazide | PPAP_HUMAN | acid phosphatase 3 | -8.66 | N/A | N/A | 11.51% | CHEMBL453954 |
| Chlorpropamide | PPAP_HUMAN | acid phosphatase 3 | -5.99 | N/A | N/A | 17.39% | CHEMBL501717 |
| Oseltamivir | PPAP_HUMAN | acid phosphatase 3 | -6.34 | N/A | N/A | 10.47% | CHEMBL507996 |
| Hydralazine | PPAP_HUMAN | acid phosphatase 3 | -7.40 | N/A | N/A | 12.39% | CHEMBL507996 |
| Omeprazole | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -7.84 | -8.58 | -8.44 | 35.81% | CHEMBL461944 |
| Hydrochlorothiazide | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -7.16 | -7.27 | -6.44 | 40.46% | CHEMBL2338476 |
| Chlorpropamide | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -7.16 | -7.69 | -7.31 | 40.00% | CHEMBL218176 |
| Oseltamivir | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -6.69 | -6.55 | -6.48 | 45.69% | CHEMBL1836976 |
| Hydralazine | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -6.58 | -6.87 | -6.31 | 25.00% | CHEMBL202617 |
| Omeprazole | PRGR_HUMAN | progesterone receptor | -6.88 | -7.08 | -8.09 | 32.52% | CHEMBL3605924 |
| Hydrochlorothiazide | PRGR_HUMAN | progesterone receptor | -7.53 | -7.38 | -7.18 | 45.83% | CHEMBL3912431 |
| Chlorpropamide | PRGR_HUMAN | progesterone receptor | -7.31 | -7.17 | -6.99 | 42.86% | CHEMBL3915906 |
| Oseltamivir | PRGR_HUMAN | progesterone receptor | -7.33 | -7.30 | -7.23 | 43.70% | CHEMBL3695612 |
| Hydralazine | PRGR_HUMAN | progesterone receptor | -6.88 | -6.85 | -6.98 | 26.97% | CHEMBL1672540 |
| Omeprazole | PTGES_HUMAN | prostaglandin E synthase | -7.72 | N/A | N/A | 34.38% | CHEMBL3342708 |
| Hydrochlorothiazide | PTGES_HUMAN | prostaglandin E synthase | -6.92 | N/A | N/A | 30.07% | CHEMBL3092269 |
| Chlorpropamide | PTGES_HUMAN | prostaglandin E synthase | -7.06 | N/A | N/A | 35.59% | CHEMBL3356955 |
| Oseltamivir | PTGES_HUMAN | prostaglandin E synthase | -6.03 | N/A | N/A | 35.04% | CHEMBL3289097 |
| Hydralazine | PTGES_HUMAN | prostaglandin E synthase | -6.87 | N/A | N/A | 26.73% | CHEMBL4093446 |
| Omeprazole | SC6A4_HUMAN | solute carrier family 6 member 4 | -8.58 | -8.58 | -8.69 | 38.41% | CHEMBL440584 |
| Hydrochlorothiazide | SC6A4_HUMAN | solute carrier family 6 member 4 | -7.47 | -7.39 | -7.79 | 30.08% | CHEMBL71 |
| Chlorpropamide | SC6A4_HUMAN | solute carrier family 6 member 4 | -7.12 | -7.29 | -7.50 | 41.24% | CHEMBL512665 |
| Oseltamivir | SC6A4_HUMAN | solute carrier family 6 member 4 | -7.15 | -7.16 | -7.61 | 42.29% | CHEMBL421546 |
| Hydralazine | SC6A4_HUMAN | solute carrier family 6 member 4 | -7.35 | -7.12 | -7.40 | 39.29% | CHEMBL1172526 |
| Omeprazole | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.95 | N/A | N/A | 32.93% | CHEMBL1313991 |
| Hydrochlorothiazide | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -6.86 | N/A | N/A | 35.88% | CHEMBL4060154 |
| Chlorpropamide | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.57 | N/A | N/A | 33.08% | CHEMBL3682646 |
| Oseltamivir | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -5.71 | N/A | N/A | 30.52% | CHEMBL4077213 |
| Hydralazine | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.09 | N/A | N/A | 30.83% | CHEMBL3914908 |
| Omeprazole | TLR4_HUMAN | toll like receptor 4 | -7.42 | -7.29 | -7.37 | 29.20% | CHEMBL4068003 |
| Hydrochlorothiazide | TLR4_HUMAN | toll like receptor 4 | -6.23 | -6.51 | -6.96 | 25.47% | CHEMBL3823499 |
| Chlorpropamide | TLR4_HUMAN | toll like receptor 4 | -6.57 | -6.22 | -6.62 | 19.59% | CHEMBL3823499 |
| Oseltamivir | TLR4_HUMAN | toll like receptor 4 | -6.32 | -5.97 | -6.09 | 38.78% | CHEMBL2364541 |
| Hydralazine | TLR4_HUMAN | toll like receptor 4 | -6.03 | -6.23 | -6.36 | 31.36% | CHEMBL3823499 |
| Omeprazole | TNFA_HUMAN | tumor necrosis factor | -7.51 | N/A | N/A | 31.16% | CHEMBL3972551 |
| Hydrochlorothiazide | TNFA_HUMAN | tumor necrosis factor | -6.93 | N/A | N/A | 33.33% | CHEMBL1709705 |
| Chlorpropamide | TNFA_HUMAN | tumor necrosis factor | -6.89 | N/A | N/A | 32.69% | CHEMBL1709705 |
| Oseltamivir | TNFA_HUMAN | tumor necrosis factor | -6.26 | N/A | N/A | 33.95% | CHEMBL2337619 |
| Hydralazine | TNFA_HUMAN | tumor necrosis factor | -6.24 | N/A | N/A | 22.13% | CHEMBL3892871 |
| Omeprazole | TRBM_HUMAN | thrombomodulin | -8.29 | -7.62 | N/A | N/A | N/A |
| Hydrochlorothiazide | TRBM_HUMAN | thrombomodulin | -6.92 | -6.42 | N/A | N/A | N/A |
| Chlorpropamide | TRBM_HUMAN | thrombomodulin | -6.80 | -6.80 | N/A | N/A | N/A |
| Oseltamivir | TRBM_HUMAN | thrombomodulin | -6.49 | -6.25 | N/A | N/A | N/A |
| Hydralazine | TRBM_HUMAN | thrombomodulin | -6.54 | -6.02 | N/A | N/A | N/A |
| Omeprazole | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -7.66 | -8.08 | N/A | N/A | N/A |
| Hydrochlorothiazide | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -6.95 | -6.37 | N/A | N/A | N/A |
| Chlorpropamide | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -6.09 | -6.67 | N/A | N/A | N/A |
| Oseltamivir | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -6.37 | -5.60 | N/A | N/A | N/A |
| Hydralazine | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -6.81 | -7.30 | N/A | N/A | N/A |
| Omeprazole | TRPM8_FICAL | Uncharacterized protein | -8.36 | N/A | N/A | N/A | N/A |
| Hydrochlorothiazide | TRPM8_FICAL | Uncharacterized protein | -7.60 | N/A | N/A | N/A | N/A |
| Chlorpropamide | TRPM8_FICAL | Uncharacterized protein | -6.91 | N/A | N/A | N/A | N/A |
| Oseltamivir | TRPM8_FICAL | Uncharacterized protein | -7.64 | N/A | N/A | N/A | N/A |
| Hydralazine | TRPM8_FICAL | Uncharacterized protein | -6.84 | N/A | N/A | N/A | N/A |
| Omeprazole | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -8.27 | N/A | N/A | 31.75% | CHEMBL199393 |
| Hydrochlorothiazide | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -6.16 | N/A | N/A | 31.25% | CHEMBL1779668 |
| Chlorpropamide | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -7.51 | N/A | N/A | 36.94% | CHEMBL197770 |
| Oseltamivir | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -6.74 | N/A | N/A | 38.46% | CHEMBL97968 |
| Hydralazine | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -7.24 | N/A | N/A | 31.34% | CHEMBL342003 |
| Omeprazole | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -7.09 | -7.93 | N/A | N/A | N/A |
| Hydrochlorothiazide | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -7.06 | -7.24 | N/A | N/A | N/A |
| Chlorpropamide | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -6.48 | -7.25 | N/A | N/A | N/A |
| Oseltamivir | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -7.03 | -6.60 | N/A | N/A | N/A |
| Hydralazine | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -6.94 | -6.85 | N/A | N/A | N/A |
| Omeprazole | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -6.78 | -7.36 | N/A | 27.70% | CHEMBL3902585 |
| Hydrochlorothiazide | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -5.30 | -6.78 | N/A | 26.09% | CHEMBL3692265 |
| Chlorpropamide | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -6.11 | -5.88 | N/A | 28.57% | CHEMBL3692265 |
| Oseltamivir | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -5.90 | -6.46 | N/A | 23.83% | CHEMBL3664218 |
| Hydralazine | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -5.57 | -6.08 | N/A | 20.44% | CHEMBL3692278 |
| Omeprazole | TRXR1_HUMAN | thioredoxin reductase 1 | -7.40 | -8.68 | -6.35 | N/A | N/A |
| Hydrochlorothiazide | TRXR1_HUMAN | thioredoxin reductase 1 | -6.92 | -6.89 | -6.08 | N/A | N/A |
| Chlorpropamide | TRXR1_HUMAN | thioredoxin reductase 1 | -7.20 | -7.16 | -5.21 | N/A | N/A |
| Oseltamivir | TRXR1_HUMAN | thioredoxin reductase 1 | -6.50 | -7.07 | -5.37 | N/A | N/A |
| Hydralazine | TRXR1_HUMAN | thioredoxin reductase 1 | -7.21 | -7.17 | -5.86 | N/A | N/A |
| Omeprazole | TRY1_HUMAN | serine protease 1 | -6.77 | N/A | N/A | 37.89% | CHEMBL24907 |
| Hydrochlorothiazide | TRY1_HUMAN | serine protease 1 | -5.48 | N/A | N/A | 31.11% | CHEMBL1160812 |
| Chlorpropamide | TRY1_HUMAN | serine protease 1 | -6.58 | N/A | N/A | 37.50% | CHEMBL156858 |
| Oseltamivir | TRY1_HUMAN | serine protease 1 | -5.36 | N/A | N/A | 40.54% | CHEMBL141574 |
| Hydralazine | TRY1_HUMAN | serine protease 1 | -5.34 | N/A | N/A | 28.87% | CHEMBL96433 |