| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.05 | -7.34 | -8.59 | 55.26% | CHEMBL160096 | Active | 54.08% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.21 | -8.38 | -7.35 | 50.96% | CHEMBL29951 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.32 | -6.18 | -7.29 | 50.96% | CHEMBL29951 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -7.80 | -6.80 | -6.54 | 32.58% | CHEMBL137781 | Active | 55.96% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -8.81 | -8.62 | -8.78 | 29.85% | CHEMBL3616488 | Inactive | 62.69% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.05 | -8.02 | N/A | 53.99% | CHEMBL4206824 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.57 | -8.91 | -7.81 | 45.83% | CHEMBL4472703 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -7.86 | -7.39 | N/A | 46.67% | CHEMBL155388 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -8.38 | -8.74 | -7.64 | 40.33% | CHEMBL4580044 | Inactive | 64.98% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.71 | -7.70 | -8.24 | 51.02% | CHEMBL278751 | Inactive | 54.96% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -7.70 | -7.71 | -8.24 | 40.10% | CHEMBL464099 | Active | 65.92% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -9.01 | -8.52 | -7.52 | 47.34% | CHEMBL70048 | Active | 64.17% |
| AA1R_HUMAN | adenosine A1 receptor | -7.49 | -8.42 | -5.99 | 37.70% | CHEMBL1269107 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -6.15 | -6.55 | -7.67 | 42.25% | CHEMBL539454 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.23 | -8.43 | -8.43 | 30.08% | CHEMBL432273 | Inactive | 65.72% |
| AA3R_HUMAN | adenosine A3 receptor | -4.48 | -3.02 | -7.86 | 30.93% | CHEMBL3601563 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.85 | 9.21 | N/A | 43.68% | CHEMBL148450 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.15 | -8.81 | -8.19 | 45.70% | CHEMBL4085150 | Active | 64.57% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.97 | -9.89 | -9.13 | 46.00% | CHEMBL4075227 | Active | 53.67% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.76 | -6.03 | N/A | 43.23% | CHEMBL1101 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -8.90 | -8.22 | -7.34 | 40.10% | CHEMBL2312378 | Active | 77.59% |
| ACTHR_HUMAN | melanocortin 2 receptor | -8.94 | -8.79 | -8.84 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.25 | -7.58 | -8.63 | 49.32% | CHEMBL299031 | Active | 58.87% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -3.46 | -7.21 | 0.64 | 52.83% | CHEMBL50588 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -7.83 | -3.39 | -5.98 | 45.21% | CHEMBL4513786 | Inactive | 99.99% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 3.70 | 3.87 | 2.65 | 52.83% | CHEMBL50588 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -8.03 | -8.03 | -8.27 | 44.07% | CHEMBL498531 | Active | 57.38% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.41 | -7.12 | -9.02 | 45.30% | CHEMBL1714856 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -7.96 | -7.07 | -7.94 | 45.09% | CHEMBL498305 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -7.45 | -7.84 | -7.62 | 47.76% | CHEMBL154057 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -8.92 | -9.79 | -9.13 | 34.55% | CHEMBL2105864 | Inactive | 66.12% |
| CALCR_HUMAN | calcitonin receptor | -7.60 | -7.92 | -7.81 | 33.18% | CHEMBL2369895 | Inactive | 98.18% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.27 | -7.75 | -8.51 | 33.04% | CHEMBL4467402 | Inactive | 95.34% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -6.95 | -7.51 | -7.23 | 38.04% | CHEMBL33277 | Inactive | 96.06% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.90 | -8.24 | -7.67 | 46.56% | CHEMBL3417216 | Inactive | 51.40% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -6.48 | -6.32 | -6.45 | 32.95% | CHEMBL1621896 | Inactive | 79.69% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -7.88 | -7.77 | -7.95 | 43.01% | CHEMBL368183 | Inactive | 95.15% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -7.66 | -8.07 | -8.96 | 32.73% | CHEMBL3597526 | Inactive | 91.21% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.83 | -8.11 | -7.13 | 55.03% | CHEMBL344623 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -9.15 | -8.75 | N/A | 53.14% | CHEMBL4089791 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.89 | N/A | N/A | 31.25% | CHEMBL220182 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -7.97 | -6.96 | -7.57 | 36.41% | CHEMBL3645131 | Inactive | 67.92% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.50 | -8.28 | -8.14 | 43.72% | CHEMBL3697082 | Inactive | 90.50% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.30 | -6.88 | -7.98 | 45.83% | CHEMBL2029611 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -7.84 | -9.10 | -8.54 | 53.47% | CHEMBL405519 | Active | 87.52% |
| DRD2_HUMAN | dopamine receptor D2 | -7.50 | N/A | N/A | 53.47% | CHEMBL405519 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.66 | N/A | N/A | 51.23% | CHEMBL170976 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -7.97 | -8.23 | N/A | 51.02% | CHEMBL27441 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -7.73 | -7.46 | -5.92 | 46.83% | CHEMBL3577346 | Inactive | 78.44% |
| EDNRA_HUMAN | endothelin receptor type A | -7.26 | -7.41 | -7.65 | 52.20% | CHEMBL323951 | Active | 66.13% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 3.29 | 2.83 | 15.98 | 21.29% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -7.96 | -7.32 | -6.42 | 45.19% | CHEMBL452991 | Inactive | 73.69% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -8.00 | -6.89 | -6.61 | 36.04% | CHEMBL2111944 | Inactive | 62.76% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -0.94 | 0.16 | -1.07 | 40.91% | CHEMBL341457 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -4.25 | -5.46 | -4.94 | 40.91% | CHEMBL341457 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 3.16 | 4.68 | 4.57 | 28.98% | CHEMBL2063423 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.13 | 1.08 | -5.96 | 38.22% | CHEMBL1289626 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -7.17 | -6.77 | -6.77 | 22.15% | CHEMBL2381641 | Inactive | 97.25% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -1.51 | 2.54 | 1.01 | 36.69% | CHEMBL432038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 4.03 | 3.36 | 6.28 | 37.28% | CHEMBL97200 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -3.99 | N/A | N/A | 45.20% | CHEMBL1277125 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -8.24 | -8.19 | -7.88 | 43.11% | CHEMBL490632 | Active | 96.98% |
| HRH3_HUMAN | histamine receptor H3 | -6.53 | -9.36 | -8.98 | 48.45% | CHEMBL4461203 | Active | 59.02% |
| HRH4_HUMAN | histamine receptor H4 | -8.11 | -8.07 | -8.62 | 32.68% | CHEMBL4102243 | Inactive | 62.88% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.56 | -7.90 | -7.33 | 40.70% | CHEMBL192450 | Inactive | 66.05% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.28 | -7.18 | -7.03 | 41.59% | CHEMBL29693 | Inactive | 88.22% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.49 | -5.34 | -4.26 | 41.36% | CHEMBL3919100 | Active | 51.50% |
| MSHR_HUMAN | melanocortin 1 receptor | -6.92 | -7.40 | -8.16 | 41.28% | CHEMBL442537 | Inactive | 55.63% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.46 | -8.23 | -7.68 | 50.31% | CHEMBL2114439 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -7.72 | -8.09 | -8.37 | 41.45% | CHEMBL504342 | Inactive | 98.26% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.34 | -7.66 | -8.68 | 33.48% | CHEMBL1940539 | Inactive | 86.85% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.12 | -7.86 | -8.12 | 36.31% | CHEMBL4442534 | Inactive | 68.80% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -7.75 | -8.70 | -7.98 | 35.43% | CHEMBL1801360 | Inactive | 64.46% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -8.80 | -8.71 | -8.77 | 43.71% | CHEMBL549377 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -7.61 | -7.75 | -7.17 | 37.16% | CHEMBL2371908 | Inactive | 95.58% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.63 | -8.97 | -8.43 | 40.33% | CHEMBL4559081 | Inactive | 90.68% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.04 | -8.09 | -7.49 | 51.70% | CHEMBL68467 | Inactive | 58.77% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.48 | -6.81 | -7.62 | 71.43% | CHEMBL110124 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.32 | -8.55 | -7.90 | 71.43% | CHEMBL110124 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.08 | -7.24 | -7.11 | 74.86% | CHEMBL257627 | Active | 73.43% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.34 | -6.86 | -7.28 | 57.84% | CHEMBL3262362 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -7.39 | -7.15 | -7.50 | 41.04% | CHEMBL97120 | Active | 55.18% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -7.25 | -8.85 | -8.63 | 47.89% | CHEMBL3211097 | Inactive | 54.08% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -8.98 | -9.96 | -8.67 | 36.49% | CHEMBL3897841 | Inactive | 85.52% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -6.99 | -7.72 | -7.91 | 41.33% | CHEMBL249741 | Inactive | 93.74% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -7.13 | -7.98 | -8.52 | 30.49% | CHEMBL4291903 | N/A | N/A |