| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.55 | -9.44 | -9.01 | 52.02% | CHEMBL1112 | Active | 92.37% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -10.08 | -9.42 | -9.60 | 48.37% | CHEMBL2424668 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.84 | -9.24 | -9.93 | 52.02% | CHEMBL1112 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -9.57 | -9.84 | -8.71 | 34.03% | CHEMBL105261 | Active | 60.45% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.20 | -9.60 | -9.72 | 41.67% | CHEMBL3616488 | Inactive | 50.39% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -10.34 | -9.85 | N/A | 52.54% | CHEMBL4064186 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -9.75 | -9.76 | -9.78 | 52.02% | CHEMBL1112 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -9.56 | -9.54 | N/A | 52.02% | CHEMBL1112 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -11.00 | -10.66 | -9.96 | 45.56% | CHEMBL2179670 | Inactive | 60.95% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -9.58 | -8.10 | -9.63 | 36.71% | CHEMBL278751 | Inactive | 54.80% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -10.06 | -9.69 | -10.64 | 52.02% | CHEMBL1112 | Active | 88.31% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -9.94 | -9.86 | -10.29 | 52.02% | CHEMBL1112 | Active | 87.25% |
| AA1R_HUMAN | adenosine A1 receptor | -8.58 | -8.64 | -8.74 | 38.64% | CHEMBL17341 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -9.19 | -8.99 | -9.82 | 42.08% | CHEMBL539454 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.96 | -8.84 | -8.68 | 38.91% | CHEMBL4069458 | Active | 54.04% |
| AA3R_HUMAN | adenosine A3 receptor | -8.74 | -6.79 | -9.60 | 38.68% | CHEMBL80 | Inactive | 69.44% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -9.76 | -5.30 | N/A | 56.33% | CHEMBL1243075 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.51 | -8.86 | -9.79 | 51.97% | CHEMBL3354075 | Active | 63.76% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -9.69 | -10.56 | -11.01 | 51.97% | CHEMBL3354074 | Active | 74.10% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.75 | -8.72 | N/A | 52.32% | CHEMBL3354072 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -9.78 | -10.07 | -10.16 | 51.97% | CHEMBL3354076 | Active | 76.94% |
| ACTHR_HUMAN | melanocortin 2 receptor | -10.49 | -10.14 | -8.68 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.66 | -9.34 | -8.46 | 46.10% | CHEMBL4072818 | Active | 51.12% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -6.24 | -8.13 | -3.54 | 52.02% | CHEMBL1112 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -11.03 | -11.22 | -11.02 | 41.71% | CHEMBL1201216 | Active | 73.37% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -3.15 | -2.39 | -3.32 | 52.02% | CHEMBL1112 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.76 | -9.69 | -9.88 | 53.99% | CHEMBL839 | Active | 79.79% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -9.99 | -9.84 | -10.75 | 45.25% | CHEMBL327519 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -10.19 | -10.17 | -9.80 | 50.56% | CHEMBL70399 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -9.61 | -9.29 | -9.38 | 37.50% | CHEMBL302102 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.77 | -10.35 | -9.97 | 40.00% | CHEMBL26908 | Inactive | 50.58% |
| CALCR_HUMAN | calcitonin receptor | -8.55 | -8.56 | -8.10 | 30.58% | CHEMBL2369907 | Inactive | 98.64% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.98 | -8.77 | -9.16 | 41.90% | CHEMBL316104 | Inactive | 67.67% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.60 | -9.63 | -8.26 | 51.60% | CHEMBL3099952 | Inactive | 54.77% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.92 | -9.17 | -8.33 | 38.57% | CHEMBL2204247 | Inactive | 54.71% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -8.48 | -8.80 | -9.20 | 38.19% | CHEMBL499852 | Inactive | 58.33% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -9.44 | -9.13 | -8.85 | 43.96% | CHEMBL402242 | Inactive | 68.17% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -9.47 | -10.03 | -10.24 | 50.26% | CHEMBL3403185 | Active | 78.49% |
| CNR1_HUMAN | cannabinoid receptor 1 | -8.40 | -9.89 | -10.87 | 50.81% | CHEMBL138667 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -10.44 | -10.27 | N/A | 58.78% | CHEMBL3323685 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.64 | N/A | N/A | 32.05% | CHEMBL220182 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -9.77 | -7.99 | -8.18 | 36.11% | CHEMBL3645131 | Inactive | 75.89% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -10.01 | -8.93 | -9.85 | 42.20% | CHEMBL3697093 | Inactive | 65.18% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -9.28 | -7.64 | -8.48 | 34.92% | CHEMBL2179709 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.63 | -9.14 | -9.66 | 52.02% | CHEMBL1112 | Active | 78.56% |
| DRD2_HUMAN | dopamine receptor D2 | -9.21 | N/A | N/A | 57.86% | CHEMBL2165124 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -9.67 | N/A | N/A | 56.44% | CHEMBL1813585 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -10.62 | -10.64 | N/A | 56.44% | CHEMBL1813585 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -10.20 | -10.59 | -10.05 | 43.20% | CHEMBL3577346 | Active | 90.74% |
| EDNRA_HUMAN | endothelin receptor type A | -8.24 | -7.83 | -7.82 | 45.05% | CHEMBL435385 | Active | 51.96% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -2.88 | -4.56 | 3.23 | 20.62% | CHEMBL392394 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.77 | -8.44 | -7.77 | 45.54% | CHEMBL59234 | Inactive | 61.17% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -9.12 | -10.85 | -9.78 | 44.00% | CHEMBL507522 | Active | 69.68% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -6.82 | -7.43 | -4.95 | 49.10% | CHEMBL187959 | Active | 67.09% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -5.04 | -7.32 | -8.84 | 45.50% | CHEMBL1630807 | Inactive | 94.41% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -0.37 | -1.18 | -2.28 | 40.91% | CHEMBL2063423 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -10.42 | -9.01 | -9.38 | 36.96% | CHEMBL206427 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -6.24 | -8.99 | -6.88 | 24.02% | CHEMBL1585091 | Inactive | 98.48% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -4.31 | -5.92 | -6.71 | 33.93% | CHEMBL432038 | Inactive | 99.82% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -1.17 | -2.76 | -3.90 | 34.52% | CHEMBL95868 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -9.64 | N/A | N/A | 52.02% | CHEMBL1112 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -11.33 | -10.25 | -11.02 | 39.79% | CHEMBL246597 | Active | 95.24% |
| HRH3_HUMAN | histamine receptor H3 | -8.77 | -9.61 | -8.92 | 57.72% | CHEMBL210252 | Active | 78.63% |
| HRH4_HUMAN | histamine receptor H4 | -9.68 | -9.22 | -9.55 | 36.57% | CHEMBL1688972 | Inactive | 62.29% |
| MC3R_HUMAN | melanocortin 3 receptor | -10.14 | -9.20 | -8.13 | 46.56% | CHEMBL250508 | Inactive | 59.29% |
| MC4R_HUMAN | melanocortin 4 receptor | -8.01 | -6.66 | -7.02 | 48.44% | CHEMBL399715 | Inactive | 88.11% |
| MC5R_HUMAN | melanocortin 5 receptor | -7.53 | -9.03 | -7.11 | 46.56% | CHEMBL140154 | Inactive | 52.81% |
| MSHR_HUMAN | melanocortin 1 receptor | -9.37 | -8.22 | -9.51 | 38.89% | CHEMBL590955 | Inactive | 63.80% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.28 | -9.49 | -8.10 | 46.75% | CHEMBL1817896 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -9.40 | -8.81 | -8.78 | 39.79% | CHEMBL443691 | Inactive | 87.28% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -8.30 | -8.09 | -8.81 | 36.60% | CHEMBL1968640 | Inactive | 74.03% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.75 | -8.38 | -7.90 | 31.82% | CHEMBL3422516 | Inactive | 66.98% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -9.02 | -10.60 | -9.59 | 39.72% | CHEMBL1801361 | Active | 63.11% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.86 | -9.24 | -9.05 | 42.94% | CHEMBL2046864 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.09 | -8.50 | -8.67 | 38.24% | CHEMBL1543306 | Inactive | 91.76% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.96 | -9.19 | -8.76 | 32.26% | CHEMBL2440193 | Inactive | 96.38% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.44 | -8.18 | -8.25 | 42.16% | CHEMBL1289387 | Active | 52.18% |
| OPRD_HUMAN | opioid receptor delta 1 | -8.24 | -7.22 | -7.87 | 53.37% | CHEMBL200881 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.37 | -9.19 | -9.95 | 53.37% | CHEMBL200881 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -9.43 | -8.25 | -8.85 | 53.37% | CHEMBL200881 | Active | 58.36% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.75 | -8.67 | -8.76 | 48.68% | CHEMBL2387198 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.22 | -9.19 | -8.57 | 39.17% | CHEMBL155975 | Inactive | 56.69% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -10.50 | -10.34 | -9.76 | 43.32% | CHEMBL1333283 | Inactive | 50.99% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -9.61 | -9.92 | -9.14 | 45.06% | CHEMBL3908443 | Inactive | 83.15% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -9.29 | -9.09 | -9.73 | 45.50% | CHEMBL251715 | Inactive | 54.56% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.66 | -9.53 | -9.12 | 30.43% | CHEMBL3884667 | N/A | N/A |