| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -7.95 | -7.89 | -8.46 | 46.40% | CHEMBL1946779 | Active | 59.62% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.68 | -8.39 | -8.68 | 41.09% | CHEMBL515472 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.41 | -8.40 | -7.51 | 43.94% | CHEMBL100086 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -7.63 | -9.30 | -8.74 | 26.52% | CHEMBL2391541 | Active | 56.49% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -8.37 | -8.28 | -8.39 | 27.15% | CHEMBL104374 | Inactive | 59.57% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.46 | -9.02 | N/A | 50.74% | CHEMBL381664 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -7.81 | -8.52 | -8.48 | 44.09% | CHEMBL454770 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.21 | -8.03 | N/A | 50.74% | CHEMBL381664 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -8.63 | -8.20 | -7.06 | 42.02% | CHEMBL1258560 | Inactive | 61.50% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.72 | -6.67 | -7.43 | 37.29% | CHEMBL278751 | Inactive | 59.35% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.16 | -7.75 | -8.10 | 44.14% | CHEMBL484608 | Active | 57.83% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.49 | -8.08 | -8.18 | 46.88% | CHEMBL487192 | Active | 58.86% |
| AA1R_HUMAN | adenosine A1 receptor | -7.94 | -8.29 | -7.22 | 36.36% | CHEMBL1544 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -7.86 | -7.96 | -9.13 | 31.95% | CHEMBL3317576 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.17 | -8.22 | -8.16 | 31.95% | CHEMBL3317576 | Inactive | 62.64% |
| AA3R_HUMAN | adenosine A3 receptor | -6.76 | -6.85 | -8.06 | 40.16% | CHEMBL513389 | Active | 50.76% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.48 | -3.85 | N/A | 43.69% | CHEMBL72506 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -8.14 | -7.79 | -8.67 | 47.41% | CHEMBL74305 | Active | 60.22% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.38 | -9.19 | -8.60 | 45.08% | CHEMBL1773265 | Active | 65.29% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.48 | -7.24 | N/A | 38.95% | CHEMBL240022 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -8.95 | -9.31 | -7.62 | 42.11% | CHEMBL3629534 | Active | 83.93% |
| ACTHR_HUMAN | melanocortin 2 receptor | -9.13 | -9.10 | -7.41 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.25 | -7.66 | -7.87 | 46.40% | CHEMBL1946779 | Active | 53.04% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -2.18 | -5.78 | -1.49 | 43.84% | CHEMBL193435 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -8.80 | -9.32 | -7.16 | 39.13% | CHEMBL1437 | Active | 60.18% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -3.12 | -2.83 | -1.09 | 43.84% | CHEMBL193435 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.03 | -7.76 | -7.78 | 50.43% | CHEMBL1086536 | Active | 62.81% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -7.22 | -7.41 | -7.93 | 50.43% | CHEMBL1086536 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -8.71 | -8.03 | -8.39 | 50.43% | CHEMBL1086536 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -7.49 | -7.55 | -7.19 | 33.74% | CHEMBL155987 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.07 | -9.09 | -9.19 | 23.36% | CHEMBL130438 | Inactive | 85.28% |
| CALCR_HUMAN | calcitonin receptor | -7.37 | -7.46 | -7.51 | 21.62% | CHEMBL2369895 | Inactive | 98.43% |
| CCKAR_HUMAN | cholecystokinin A receptor | -7.32 | -7.79 | -8.73 | 30.11% | CHEMBL249151 | Inactive | 96.13% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.99 | -7.58 | -7.60 | 40.48% | CHEMBL143690 | Inactive | 90.52% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.34 | -7.67 | -6.94 | 38.61% | CHEMBL3589844 | Inactive | 92.08% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.12 | -7.24 | -8.09 | 31.88% | CHEMBL1907216 | Inactive | 73.39% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -6.93 | -7.20 | -7.41 | 37.32% | CHEMBL504250 | Inactive | 99.05% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.00 | -8.11 | -8.74 | 37.21% | CHEMBL1214531 | Inactive | 90.76% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.11 | -9.02 | -8.54 | 60.00% | CHEMBL1923765 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -8.57 | -8.40 | N/A | 60.00% | CHEMBL1923765 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.88 | N/A | N/A | 24.62% | CHEMBL490688 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.34 | -7.52 | -7.09 | 29.05% | CHEMBL3645131 | Inactive | 65.94% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.73 | -9.01 | -8.76 | 34.23% | CHEMBL3920319 | Inactive | 87.57% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.33 | -6.99 | -8.15 | 28.32% | CHEMBL1644072 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -8.41 | -8.87 | -8.31 | 55.00% | CHEMBL431220 | Active | 70.79% |
| DRD2_HUMAN | dopamine receptor D2 | -7.72 | N/A | N/A | 50.71% | CHEMBL171826 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.02 | N/A | N/A | 50.71% | CHEMBL171825 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -8.19 | -8.36 | N/A | 49.54% | CHEMBL3800303 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -9.32 | -9.31 | -7.22 | 38.18% | CHEMBL231171 | Inactive | 66.00% |
| EDNRA_HUMAN | endothelin receptor type A | -7.25 | -7.32 | -7.36 | 54.14% | CHEMBL64200 | Active | 75.43% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -0.11 | -3.66 | 5.32 | 18.59% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -7.80 | -7.25 | -6.72 | 33.70% | CHEMBL452991 | Inactive | 83.24% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.38 | -7.63 | -7.55 | 39.45% | CHEMBL254372 | Inactive | 62.03% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -1.43 | 0.73 | -1.83 | 42.73% | CHEMBL341457 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -3.24 | -5.21 | -6.54 | 42.73% | CHEMBL341457 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 1.18 | 0.06 | -1.80 | 24.84% | CHEMBL3114673 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -10.04 | -6.02 | -6.63 | 43.86% | CHEMBL1682820 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -3.88 | -8.67 | -4.57 | 21.19% | CHEMBL275079 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -4.46 | -2.35 | -2.67 | 31.54% | CHEMBL432038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -1.87 | -1.55 | -0.89 | 31.54% | CHEMBL432038 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -6.77 | N/A | N/A | 45.04% | CHEMBL258930 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -8.79 | -7.72 | -7.80 | 41.23% | CHEMBL422931 | Active | 97.54% |
| HRH3_HUMAN | histamine receptor H3 | -7.45 | -8.61 | -8.70 | 54.13% | CHEMBL1822856 | Active | 76.34% |
| HRH4_HUMAN | histamine receptor H4 | -9.14 | -9.11 | -9.14 | 36.00% | CHEMBL1934064 | Inactive | 66.33% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.77 | -7.34 | -7.17 | 32.32% | CHEMBL380120 | Inactive | 72.47% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.17 | -6.90 | -6.84 | 34.13% | CHEMBL1501300 | Inactive | 94.09% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.97 | -7.92 | -4.67 | 24.86% | CHEMBL1209788 | Inactive | 95.39% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.46 | -7.36 | -7.63 | 32.95% | CHEMBL4113490 | Inactive | 71.25% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.01 | -7.75 | -7.83 | 54.63% | CHEMBL140101 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -7.72 | -8.20 | -8.05 | 41.45% | CHEMBL284269 | Inactive | 98.46% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.67 | -7.59 | -8.09 | 28.73% | CHEMBL2001553 | Inactive | 91.18% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -7.50 | -7.64 | -8.34 | 22.56% | CHEMBL2208334 | Inactive | 77.25% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -7.93 | -8.50 | -8.64 | 34.12% | CHEMBL1801358 | Inactive | 61.37% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -8.54 | -8.41 | -8.07 | 43.62% | CHEMBL3559801 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -7.70 | -7.61 | -7.55 | 43.62% | CHEMBL3559801 | Inactive | 91.67% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.46 | -8.53 | -8.27 | 43.62% | CHEMBL3559801 | Inactive | 74.46% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.21 | -7.68 | -7.59 | 43.62% | CHEMBL3559801 | Inactive | 69.27% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.07 | -6.35 | -6.88 | 51.46% | CHEMBL1237044 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -8.29 | -7.77 | -7.97 | 53.57% | CHEMBL2022021 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.24 | -6.99 | -7.86 | 57.55% | CHEMBL257264 | Active | 50.45% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.69 | -8.11 | -6.97 | 45.16% | CHEMBL3581755 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -7.73 | -7.51 | -7.88 | 74.73% | CHEMBL297624 | Active | 97.68% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -9.06 | -9.34 | -8.97 | 40.00% | CHEMBL3195509 | Inactive | 70.47% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -8.78 | -8.79 | -8.66 | 22.94% | CHEMBL3913851 | Inactive | 97.52% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -7.22 | -7.67 | -7.30 | 33.56% | CHEMBL3416859 | Inactive | 93.35% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.03 | -8.17 | -7.83 | 20.00% | CHEMBL3884667 | N/A | N/A |