| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -6.99 | -6.86 | -7.60 | 29.30% | CHEMBL275572 | Inactive | 81.01% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -7.56 | -6.95 | -7.31 | 28.76% | CHEMBL1279 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -7.33 | -7.28 | -6.14 | 28.76% | CHEMBL1279 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -7.26 | -7.18 | -6.61 | 25.00% | CHEMBL105261 | Inactive | 56.18% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -6.88 | -7.30 | -7.03 | 28.40% | CHEMBL102292 | Inactive | 68.93% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -7.10 | -6.92 | N/A | 30.92% | CHEMBL559251 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -6.96 | -7.19 | -7.35 | 28.91% | CHEMBL474404 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -6.94 | -7.18 | N/A | 28.24% | CHEMBL162901 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -7.76 | -7.56 | -7.15 | 27.38% | CHEMBL401607 | Inactive | 74.12% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -7.35 | -7.18 | -7.23 | 26.52% | CHEMBL270840 | Inactive | 68.51% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -6.98 | -6.71 | -7.36 | 27.81% | CHEMBL3423339 | Inactive | 64.41% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -7.31 | -7.28 | -7.13 | 29.10% | CHEMBL3959209 | Inactive | 75.50% |
| AA1R_HUMAN | adenosine A1 receptor | -7.25 | -7.00 | -7.79 | 33.76% | CHEMBL364036 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -6.82 | -7.51 | -7.20 | 29.66% | CHEMBL3093327 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -7.53 | -7.76 | -6.87 | 31.21% | CHEMBL37243 | Inactive | 59.92% |
| AA3R_HUMAN | adenosine A3 receptor | -7.14 | -7.34 | -8.13 | 33.76% | CHEMBL364036 | Active | 52.38% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.08 | -7.23 | N/A | 27.42% | CHEMBL1201353 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -6.91 | -7.38 | -7.83 | 27.27% | CHEMBL4097258 | Inactive | 77.75% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -7.00 | -8.18 | -8.23 | 28.77% | CHEMBL207287 | Inactive | 73.35% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.47 | -7.78 | N/A | 27.42% | CHEMBL1201353 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -7.96 | -7.55 | -7.87 | 27.42% | CHEMBL1201353 | Active | 62.73% |
| ACTHR_HUMAN | melanocortin 2 receptor | -7.47 | -7.22 | -7.42 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -6.89 | -7.23 | -7.21 | 30.53% | CHEMBL511411 | Active | 55.33% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -7.57 | -7.92 | -7.15 | 39.64% | CHEMBL260374 | Active | 85.34% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -7.60 | -7.76 | -7.22 | 26.67% | CHEMBL85 | Inactive | 50.72% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -4.90 | -4.46 | -4.14 | 39.64% | CHEMBL260374 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -7.38 | -7.30 | -7.18 | 23.86% | CHEMBL1814267 | Inactive | 50.58% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -7.33 | -8.19 | -7.85 | 25.83% | CHEMBL15988 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -7.01 | -7.92 | -7.04 | 27.54% | CHEMBL1085929 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -6.73 | -6.87 | -6.66 | 30.64% | CHEMBL938 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -7.66 | -8.17 | -7.96 | 22.22% | CHEMBL406291 | Inactive | 91.23% |
| CALCR_HUMAN | calcitonin receptor | -6.70 | -6.37 | -7.26 | 21.50% | CHEMBL2369907 | Inactive | 95.85% |
| CCKAR_HUMAN | cholecystokinin A receptor | -6.87 | -7.03 | -7.16 | 28.31% | CHEMBL2372623 | Inactive | 98.32% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.13 | -7.80 | -6.93 | 26.09% | CHEMBL358283 | Inactive | 98.60% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -6.20 | -6.77 | -6.21 | 35.14% | CHEMBL1829622 | Inactive | 96.42% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -6.69 | -7.09 | -7.44 | 20.73% | CHEMBL207780 | Inactive | 85.49% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -7.12 | -6.85 | -6.43 | 33.75% | CHEMBL2113088 | Inactive | 99.56% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -7.35 | -7.83 | -8.27 | 22.40% | CHEMBL143515 | Inactive | 95.48% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.20 | -7.67 | -8.09 | 33.71% | CHEMBL4109469 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -7.55 | -7.52 | N/A | 34.12% | CHEMBL3922495 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.75 | N/A | N/A | 18.03% | CHEMBL401893 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -7.79 | -6.92 | -6.47 | 23.11% | CHEMBL272105 | Inactive | 74.31% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -7.47 | -7.54 | -7.41 | 26.01% | CHEMBL1077822 | Inactive | 98.63% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.50 | -6.45 | -6.67 | 31.45% | CHEMBL3938247 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -6.91 | -6.94 | -7.57 | 29.67% | CHEMBL3697602 | Inactive | 74.11% |
| DRD2_HUMAN | dopamine receptor D2 | -7.44 | N/A | N/A | 31.58% | CHEMBL105977 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -7.11 | N/A | N/A | 31.58% | CHEMBL105977 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -7.38 | -7.06 | N/A | 32.09% | CHEMBL216794 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -7.63 | -7.74 | -7.63 | 26.03% | CHEMBL216439 | Inactive | 82.38% |
| EDNRA_HUMAN | endothelin receptor type A | -6.64 | -6.35 | -6.16 | 28.00% | CHEMBL414605 | Inactive | 83.90% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -7.01 | -6.78 | -5.94 | 16.34% | CHEMBL392394 | Inactive | 89.54% |
| GASR_HUMAN | cholecystokinin B receptor | -6.64 | -7.16 | -5.53 | 31.03% | CHEMBL36436 | Inactive | 82.98% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -8.11 | -8.09 | -7.87 | 24.38% | CHEMBL174216 | Inactive | 79.54% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -6.90 | -7.06 | -7.52 | 29.88% | CHEMBL593056 | Inactive | 75.42% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -7.59 | -8.34 | -7.91 | 22.86% | CHEMBL3401177 | Inactive | 74.32% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -5.38 | -5.51 | -4.97 | 21.20% | CHEMBL3560612 | Inactive | 95.69% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.91 | -8.38 | -8.40 | 27.37% | CHEMBL1808895 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -7.12 | -7.70 | -6.82 | 21.90% | CHEMBL2418359 | Inactive | 98.23% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.67 | -6.52 | -6.48 | 21.20% | CHEMBL3560612 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -6.64 | -6.01 | -6.73 | 21.90% | CHEMBL2418359 | Inactive | 99.39% |
| HRH1_HUMAN | histamine receptor H1 | -7.91 | N/A | N/A | 45.95% | CHEMBL1096430 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -8.69 | -7.55 | -7.73 | 46.30% | CHEMBL443896 | Active | 97.66% |
| HRH3_HUMAN | histamine receptor H3 | -7.11 | -7.03 | -7.09 | 52.69% | CHEMBL325327 | Active | 71.45% |
| HRH4_HUMAN | histamine receptor H4 | -8.03 | -7.70 | -7.44 | 52.69% | CHEMBL325327 | Active | 87.37% |
| MC3R_HUMAN | melanocortin 3 receptor | -6.75 | -6.75 | -5.89 | 32.20% | CHEMBL328117 | Inactive | 69.88% |
| MC4R_HUMAN | melanocortin 4 receptor | -5.77 | -5.81 | -6.24 | 33.70% | CHEMBL3287339 | Inactive | 78.21% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.05 | -7.28 | -6.36 | 31.11% | CHEMBL313279 | Active | 55.16% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.80 | -6.77 | -6.82 | 32.72% | CHEMBL569694 | Inactive | 62.09% |
| NK1R_HUMAN | tachykinin receptor 1 | -7.33 | -6.89 | -6.77 | 27.61% | CHEMBL393746 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -6.81 | -6.89 | -6.83 | 27.10% | CHEMBL307338 | Inactive | 99.26% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -6.82 | -6.86 | -6.52 | 19.62% | CHEMBL1705499 | Inactive | 96.82% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -6.45 | -6.10 | -6.52 | 27.01% | CHEMBL388586 | Inactive | 84.50% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -6.58 | -7.78 | -7.44 | 22.99% | CHEMBL1801269 | Inactive | 85.10% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -7.21 | -7.59 | -7.15 | 28.65% | CHEMBL428017 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -6.59 | -6.53 | -6.47 | 31.14% | CHEMBL4070864 | Inactive | 69.15% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -7.04 | -6.64 | -6.70 | 30.86% | CHEMBL2440191 | Active | 92.04% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -6.23 | -6.16 | -6.69 | 27.84% | CHEMBL2440182 | Inactive | 82.17% |
| OPRD_HUMAN | opioid receptor delta 1 | -6.48 | -5.78 | -6.26 | 50.00% | CHEMBL437372 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -7.38 | -7.52 | -6.91 | 32.62% | CHEMBL198238 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -7.15 | -7.12 | -7.01 | 50.00% | CHEMBL437372 | Inactive | 72.27% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -5.91 | -6.28 | -6.43 | 29.49% | CHEMBL3647961 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -6.52 | -6.73 | -6.63 | 22.22% | CHEMBL36154 | Inactive | 87.61% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -7.46 | -7.67 | -7.29 | 30.07% | CHEMBL1541237 | Active | 67.12% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -7.31 | -7.77 | -7.31 | 20.83% | CHEMBL3983689 | Inactive | 95.80% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -6.88 | -6.52 | -7.82 | 23.08% | CHEMBL41547 | Inactive | 97.98% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -6.53 | -6.79 | -6.95 | 27.75% | CHEMBL3884667 | N/A | N/A |