Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | ||||
5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.75 | -9.63 | -9.81 | 39.01% | CHEMBL485427 |
5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -10.70 | -9.48 | N/A | 47.37% | CHEMBL4084262 |
5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -9.51 | -9.73 | -9.88 | 35.21% | CHEMBL1201216 |
5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -9.80 | -10.03 | N/A | 47.37% | CHEMBL4084262 |
AA1R_HUMAN | adenosine A1 receptor | -8.84 | -8.40 | -8.67 | 35.09% | CHEMBL3317560 |
AA2AR_HUMAN | adenosine A2a receptor | -8.97 | -9.18 | -8.97 | 37.95% | CHEMBL2070717 |
ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -10.60 | -9.60 | -9.15 | 37.73% | CHEMBL432376 |
ACE_HUMAN | angiotensin I converting enzyme | -9.09 | -8.72 | -7.26 | 35.42% | CHEMBL301751 |
ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -6.67 | N/A | N/A | 24.07% | CHEMBL386114 |
ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -6.07 | -5.88 | -6.49 | N/A | N/A |
ACM1_HUMAN | cholinergic receptor muscarinic 1 | -9.73 | 1.55 | N/A | 45.00% | CHEMBL3912801 |
ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.50 | -8.34 | N/A | 40.32% | CHEMBL244946 |
ADRB2_HUMAN | adrenoceptor beta 2 | -8.74 | -9.20 | -10.21 | 50.25% | CHEMBL1586182 |
AGTR2_HUMAN | angiotensin II receptor type 2 | -9.33 | -10.02 | -9.34 | 32.45% | CHEMBL348126 |
ALDR_HUMAN | aldo-keto reductase family 1 member B | -9.34 | -9.90 | -9.96 | 32.30% | CHEMBL342974 |
AMPN_HUMAN | alanyl aminopeptidase, membrane | -8.87 | -9.47 | -8.37 | 32.40% | CHEMBL1798008 |
AOFA_HUMAN | monoamine oxidase A | -9.79 | -9.80 | -10.73 | 33.18% | CHEMBL3407586 |
AOFB_HUMAN | monoamine oxidase B | -10.99 | -10.67 | -10.61 | 32.72% | CHEMBL3407581 |
BACE1_HUMAN | beta-secretase 1 | -7.54 | -7.69 | -8.22 | 35.82% | CHEMBL3896157 |
CAH2_HUMAN | carbonic anhydrase 2 | -8.22 | -8.33 | -8.17 | 41.63% | CHEMBL3337996 |
CASP1_HUMAN | caspase 1 | -6.86 | -7.48 | -7.39 | 30.56% | CHEMBL25864 |
CDK5_HUMAN | cyclin dependent kinase 5 | -8.45 | -8.75 | -8.40 | 36.14% | CHEMBL2002613 |
CHLE_HUMAN | butyrylcholinesterase | -9.47 | -10.07 | -10.11 | 36.05% | CHEMBL388615 |
CNR1_HUMAN | cannabinoid receptor 1 | -9.50 | -9.73 | -10.58 | 41.06% | CHEMBL560463 |
CNR2_HUMAN | cannabinoid receptor 2 | -10.64 | -10.47 | N/A | 55.20% | CHEMBL496781 |
COLI_HUMAN | proopiomelanocortin | -8.91 | -8.86 | -9.03 | N/A | N/A |
COMT_HUMAN | catechol-O-methyltransferase | -6.71 | -6.34 | -6.58 | 32.03% | CHEMBL3425739 |
CRP_HUMAN | C-reactive protein | -5.95 | -6.01 | N/A | N/A | N/A |
CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -3.80 | N/A | N/A | 30.83% | CHEMBL3426944 |
CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -9.19 | -8.49 | -8.37 | 34.47% | CHEMBL1644072 |
DRD2_HUMAN | dopamine receptor D2 | -8.10 | N/A | N/A | 45.00% | CHEMBL3912801 |
DRD3_HUMAN | dopamine receptor D3 | -9.10 | N/A | N/A | 47.37% | CHEMBL4084262 |
DRD4_HUMAN | dopamine receptor D4 | -10.66 | -10.70 | N/A | 38.91% | CHEMBL220754 |
EDN1_HUMAN | endothelin 1 | -9.52 | N/A | N/A | N/A | N/A |
ESR1_HUMAN | estrogen receptor 1 | -9.25 | -8.86 | -9.05 | 33.71% | CHEMBL240438 |
FABP5_HUMAN | fatty acid binding protein 5 | -9.56 | -6.51 | -6.70 | 27.54% | CHEMBL247920 |
FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -9.32 | N/A | N/A | 35.57% | CHEMBL1991078 |
GLRA3_HUMAN | glycine receptor alpha 3 | -8.86 | -9.61 | -9.69 | 25.60% | CHEMBL4070615 |
GLRA3_HUMAN | glycine receptor alpha 3 | -9.93 | N/A | N/A | 25.60% | CHEMBL4070615 |
GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.98 | -6.62 | -7.17 | 34.24% | CHEMBL3633976 |
HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -8.73 | -8.26 | -8.35 | 35.81% | CHEMBL3650205 |
HRH1_HUMAN | histamine receptor H1 | -9.47 | N/A | N/A | 46.27% | CHEMBL271066 |
HYES_HUMAN | epoxide hydrolase 2 | -8.61 | -8.38 | -8.25 | 35.47% | CHEMBL3677986 |
IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -8.70 | N/A | N/A | 35.21% | CHEMBL1807620 |
MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -8.39 | -8.92 | N/A | 36.65% | CHEMBL259690 |
MIF_HUMAN | macrophage migration inhibitory factor | -5.60 | -7.23 | -6.47 | 27.38% | CHEMBL3897449 |
MK01_HUMAN | mitogen-activated protein kinase 1 | -8.32 | -8.47 | -8.40 | 37.25% | CHEMBL3968650 |
MK03_HUMAN | mitogen-activated protein kinase 3 | -8.42 | -9.21 | -8.28 | 30.13% | CHEMBL1336 |
MTOR_HUMAN | mechanistic target of rapamycin kinase | -10.34 | -10.05 | -9.76 | 33.12% | CHEMBL1091706 |
NEP_HUMAN | membrane metalloendopeptidase | -7.98 | -7.67 | -9.01 | 35.42% | CHEMBL301751 |
NK1R_HUMAN | tachykinin receptor 1 | -9.08 | -9.38 | -8.99 | 48.37% | CHEMBL361031 |
NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -9.47 | -9.04 | -10.30 | 20.19% | CHEMBL284237 |
NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -10.81 | -10.15 | -10.53 | 41.58% | CHEMBL146764 |
NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -9.82 | -8.25 | -10.30 | 30.92% | CHEMBL162577 |
NOS1_HUMAN | nitric oxide synthase 1 | -9.42 | -9.45 | -8.63 | 32.30% | CHEMBL3217000 |
NOS2_HUMAN | nitric oxide synthase 2 | -8.42 | -8.53 | -6.61 | 31.73% | CHEMBL1911986 |
NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -8.81 | -8.66 | -8.70 | 37.87% | CHEMBL1938736 |
OPRD_HUMAN | opioid receptor delta 1 | -8.73 | -7.25 | -8.08 | 41.07% | CHEMBL199378 |
OPRK_HUMAN | opioid receptor kappa 1 | -9.90 | -9.25 | -9.85 | 41.07% | CHEMBL199378 |
OPRM_MOUSE | Mu-type opioid receptor | -9.09 | -8.63 | N/A | 33.92% | CHEMBL2417568 |
OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.00 | -7.98 | -8.20 | 35.00% | CHEMBL3349269 |
P2RX3_HUMAN | purinergic receptor P2X 3 | -6.94 | -6.20 | -5.94 | 34.33% | CHEMBL3684612 |
P2Y12_HUMAN | purinergic receptor P2Y12 | -10.22 | -7.50 | -9.16 | 31.27% | CHEMBL3326906 |
PAR1_HUMAN | coagulation factor II thrombin receptor | -8.80 | N/A | N/A | 31.34% | CHEMBL3704471 |
PDE4B_HUMAN | phosphodiesterase 4B | -9.65 | -9.61 | -9.68 | 37.22% | CHEMBL286291 |
PDE5A_HUMAN | phosphodiesterase 5A | -7.57 | -10.12 | -9.96 | 36.43% | CHEMBL393913 |
PERM_HUMAN | myeloperoxidase | -8.23 | -9.05 | -8.27 | 27.07% | CHEMBL3343353 |
PGH1_SHEEP | Prostaglandin G/H synthase 1 | -8.95 | -7.28 | -9.80 | 31.74% | CHEMBL1201124 |
PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -3.57 | -7.53 | -9.45 | 35.69% | CHEMBL317321 |
PPAP_HUMAN | acid phosphatase 3 | -7.74 | N/A | N/A | 20.00% | CHEMBL507996 |
PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -8.70 | -9.63 | -8.47 | 37.36% | CHEMBL4069917 |
PRGR_HUMAN | progesterone receptor | -6.92 | -6.26 | -9.71 | 37.28% | CHEMBL562509 |
PTGES_HUMAN | prostaglandin E synthase | -7.59 | N/A | N/A | 60.59% | CHEMBL2336496 |
SC6A4_HUMAN | solute carrier family 6 member 4 | -9.02 | -10.21 | -9.56 | 36.96% | CHEMBL470849 |
SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.99 | N/A | N/A | 38.31% | CHEMBL2296304 |
TLR4_HUMAN | toll like receptor 4 | -9.23 | -8.55 | -8.77 | 33.20% | CHEMBL4068003 |
TNFA_HUMAN | tumor necrosis factor | -7.51 | N/A | N/A | 37.60% | CHEMBL142115 |
TRBM_HUMAN | thrombomodulin | -9.15 | -7.50 | N/A | N/A | N/A |
TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -8.14 | -8.73 | N/A | N/A | N/A |
TRPM8_FICAL | Uncharacterized protein | -9.53 | N/A | N/A | N/A | N/A |
TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -9.67 | N/A | N/A | 33.84% | CHEMBL3689047 |
TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -7.91 | -8.51 | N/A | N/A | N/A |
TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -7.77 | -7.21 | N/A | 43.04% | CHEMBL3984832 |
TRXR1_HUMAN | thioredoxin reductase 1 | -8.00 | -8.09 | -6.79 | N/A | N/A |
TRY1_HUMAN | serine protease 1 | -6.59 | N/A | N/A | 38.80% | CHEMBL280769 |