Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | ||||
5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -7.75 | -8.49 | -6.96 | 28.88% | CHEMBL350153 |
5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -7.14 | -7.36 | N/A | 36.36% | CHEMBL80093 |
5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -7.15 | -7.18 | -7.53 | 36.08% | CHEMBL3898995 |
5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -7.20 | -7.62 | N/A | 33.51% | CHEMBL325674 |
AA1R_HUMAN | adenosine A1 receptor | -6.38 | -7.73 | -4.71 | 46.31% | CHEMBL329774 |
AA2AR_HUMAN | adenosine A2a receptor | -6.33 | -6.59 | -6.34 | 34.04% | CHEMBL3350613 |
ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -8.90 | -7.81 | -8.48 | 32.54% | CHEMBL183394 |
ACE_HUMAN | angiotensin I converting enzyme | -8.23 | -8.03 | -7.39 | 40.41% | CHEMBL342373 |
ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -5.97 | N/A | N/A | 25.23% | CHEMBL386114 |
ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -4.88 | -5.92 | -8.94 | N/A | N/A |
ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.96 | -3.43 | N/A | 45.04% | CHEMBL2022942 |
ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.74 | -6.58 | N/A | 40.16% | CHEMBL294273 |
ADRB2_HUMAN | adrenoceptor beta 2 | -7.68 | -7.47 | -8.88 | 33.11% | CHEMBL75753 |
AGTR2_HUMAN | angiotensin II receptor type 2 | -7.04 | -7.22 | -7.00 | 34.12% | CHEMBL3350599 |
ALDR_HUMAN | aldo-keto reductase family 1 member B | -6.99 | -6.07 | -6.35 | 26.24% | CHEMBL84446 |
AMPN_HUMAN | alanyl aminopeptidase, membrane | -9.13 | -7.80 | -8.03 | 37.89% | CHEMBL2022238 |
AOFA_HUMAN | monoamine oxidase A | -7.84 | -7.64 | -6.84 | 23.85% | CHEMBL394864 |
AOFB_HUMAN | monoamine oxidase B | -8.10 | -6.73 | -7.09 | 25.87% | CHEMBL4302260 |
BACE1_HUMAN | beta-secretase 1 | -6.49 | -6.67 | -7.45 | 38.22% | CHEMBL451950 |
CAH2_HUMAN | carbonic anhydrase 2 | -7.50 | -7.16 | -6.83 | 38.58% | CHEMBL1956757 |
CASP1_HUMAN | caspase 1 | -6.47 | -6.64 | -6.60 | 39.41% | CHEMBL196571 |
CDK5_HUMAN | cyclin dependent kinase 5 | -6.29 | -6.82 | -5.43 | 27.01% | CHEMBL1980995 |
CHLE_HUMAN | butyrylcholinesterase | -8.01 | -7.84 | -7.86 | 33.33% | CHEMBL504924 |
CNR1_HUMAN | cannabinoid receptor 1 | -6.87 | -7.57 | -5.25 | 31.58% | CHEMBL527071 |
CNR2_HUMAN | cannabinoid receptor 2 | -8.02 | -7.68 | N/A | 36.72% | CHEMBL494564 |
COLI_HUMAN | proopiomelanocortin | -7.36 | -7.36 | -6.46 | N/A | N/A |
COMT_HUMAN | catechol-O-methyltransferase | -4.72 | -6.31 | -4.95 | 26.38% | CHEMBL3819488 |
CRP_HUMAN | C-reactive protein | -6.33 | -6.25 | N/A | N/A | N/A |
CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -8.99 | N/A | N/A | 20.71% | CHEMBL3701188 |
CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.42 | -7.20 | -7.11 | 36.09% | CHEMBL1949888 |
DRD2_HUMAN | dopamine receptor D2 | -6.28 | N/A | N/A | 35.62% | CHEMBL541435 |
DRD3_HUMAN | dopamine receptor D3 | -7.40 | N/A | N/A | 35.62% | CHEMBL541435 |
DRD4_HUMAN | dopamine receptor D4 | -7.73 | -7.43 | N/A | 30.81% | CHEMBL165113 |
EDN1_HUMAN | endothelin 1 | -6.94 | N/A | N/A | N/A | N/A |
ESR1_HUMAN | estrogen receptor 1 | -6.84 | -6.76 | -6.61 | 31.58% | CHEMBL4526659 |
FABP5_HUMAN | fatty acid binding protein 5 | -7.62 | -6.34 | -6.28 | 21.18% | CHEMBL4278244 |
FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -6.77 | N/A | N/A | 32.14% | CHEMBL2221249 |
GLRA3_HUMAN | glycine receptor alpha 3 | -7.95 | -7.75 | -7.93 | 16.79% | CHEMBL4070615 |
GLRA3_HUMAN | glycine receptor alpha 3 | -7.88 | N/A | N/A | 16.79% | CHEMBL4070615 |
GRM5_HUMAN | glutamate metabotropic receptor 5 | -8.40 | -4.58 | -4.42 | 35.62% | CHEMBL3087505 |
HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.98 | -6.87 | -6.50 | 34.36% | CHEMBL3698278 |
HRH1_HUMAN | histamine receptor H1 | -5.10 | N/A | N/A | 34.43% | CHEMBL96467 |
HYES_HUMAN | epoxide hydrolase 2 | -8.70 | -8.63 | -7.22 | 42.34% | CHEMBL3222124 |
IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -6.02 | N/A | N/A | 29.85% | CHEMBL1672879 |
MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -7.39 | -7.16 | N/A | 37.14% | CHEMBL4474330 |
MIF_HUMAN | macrophage migration inhibitory factor | -5.49 | -6.01 | -5.75 | 22.06% | CHEMBL554271 |
MK01_HUMAN | mitogen-activated protein kinase 1 | -6.85 | -7.51 | -6.70 | 31.72% | CHEMBL3663012 |
MK03_HUMAN | mitogen-activated protein kinase 3 | -6.29 | -6.78 | -6.70 | 28.66% | CHEMBL3113587 |
MTOR_HUMAN | mechanistic target of rapamycin kinase | -6.91 | -7.36 | -7.04 | 32.80% | CHEMBL371029 |
NEP_HUMAN | membrane metalloendopeptidase | -7.74 | -7.68 | -7.40 | 32.92% | CHEMBL3677668 |
NK1R_HUMAN | tachykinin receptor 1 | -7.52 | -7.06 | -6.64 | 37.50% | CHEMBL3922759 |
NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -7.79 | -7.77 | -7.51 | 11.86% | CHEMBL2333945 |
NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -8.66 | -8.40 | -6.87 | 30.54% | CHEMBL4169479 |
NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -7.73 | -7.47 | -7.51 | 23.98% | CHEMBL354003 |
NOS1_HUMAN | nitric oxide synthase 1 | -7.00 | -7.52 | -8.65 | 40.94% | CHEMBL1270460 |
NOS2_HUMAN | nitric oxide synthase 2 | -7.40 | -8.18 | -8.31 | 36.03% | CHEMBL1037 |
NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -6.79 | -6.85 | -7.13 | 29.34% | CHEMBL4541382 |
OPRD_HUMAN | opioid receptor delta 1 | -6.46 | -6.22 | -6.00 | 37.95% | CHEMBL1791447 |
OPRK_HUMAN | opioid receptor kappa 1 | -7.19 | -7.26 | -6.92 | 38.82% | CHEMBL396460 |
OPRM_MOUSE | Mu-type opioid receptor | -7.28 | -7.05 | N/A | 36.73% | CHEMBL440765 |
OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.20 | -7.16 | -7.32 | 38.82% | CHEMBL396460 |
P2RX3_HUMAN | purinergic receptor P2X 3 | -5.91 | -6.35 | -5.86 | 26.85% | CHEMBL3908238 |
P2Y12_HUMAN | purinergic receptor P2Y12 | -6.62 | -5.74 | -7.12 | 32.43% | CHEMBL590254 |
PAR1_HUMAN | coagulation factor II thrombin receptor | -8.29 | N/A | N/A | 40.62% | CHEMBL3658410 |
PDE4B_HUMAN | phosphodiesterase 4B | -7.84 | -8.05 | -8.14 | 31.95% | CHEMBL144633 |
PDE5A_HUMAN | phosphodiesterase 5A | -7.70 | -7.65 | -7.50 | 31.88% | CHEMBL484065 |
PERM_HUMAN | myeloperoxidase | -6.79 | -7.11 | -7.10 | 24.12% | CHEMBL490 |
PGH1_SHEEP | Prostaglandin G/H synthase 1 | -5.50 | -5.73 | -5.40 | 31.25% | CHEMBL4535676 |
PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -1.65 | -3.46 | -6.92 | 33.33% | CHEMBL4529874 |
PPAP_HUMAN | acid phosphatase 3 | -7.72 | -8.65 | N/A | 12.00% | CHEMBL507996 |
PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -6.63 | -5.95 | -6.42 | 28.74% | CHEMBL1836929 |
PRGR_HUMAN | progesterone receptor | -7.91 | -8.04 | -7.57 | 26.63% | CHEMBL384975 |
PTGES_HUMAN | prostaglandin E synthase | -6.80 | N/A | N/A | 27.81% | CHEMBL3947494 |
SC6A4_HUMAN | solute carrier family 6 member 4 | -8.70 | -8.04 | -8.48 | 33.33% | CHEMBL3818117 |
SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -8.30 | N/A | N/A | 100.00% | CHEMBL501134 |
TLR4_HUMAN | toll like receptor 4 | -6.87 | -7.32 | -7.67 | 32.47% | CHEMBL3354640 |
TNFA_HUMAN | tumor necrosis factor | -7.20 | -6.42 | -5.34 | 31.08% | CHEMBL4299667 |
TRBM_HUMAN | thrombomodulin | -6.53 | -7.55 | N/A | N/A | N/A |
TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -7.24 | -6.67 | N/A | 13.83% | CHEMBL1408302 |
TRPM8_FICAL | Uncharacterized protein | -8.07 | N/A | N/A | N/A | N/A |
TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -6.65 | N/A | N/A | 30.86% | CHEMBL239389 |
TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -7.80 | -7.60 | N/A | N/A | N/A |
TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -5.23 | -6.45 | N/A | 23.42% | CHEMBL3696433 |
TRXR1_HUMAN | thioredoxin reductase 1 | -7.48 | -7.49 | -6.50 | 22.58% | CHEMBL4459518 |
TRY1_HUMAN | serine protease 1 | -6.10 | N/A | N/A | 46.36% | CHEMBL112726 |