| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.50 | -8.26 | -10.08 | 70.94% | CHEMBL1221452 | Active | 93.27% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.95 | -9.41 | -9.81 | 53.85% | CHEMBL292759 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.84 | -9.08 | -8.14 | 53.85% | CHEMBL292759 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -9.63 | -9.12 | -8.83 | 39.15% | CHEMBL29410 | Inactive | 50.02% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.40 | -9.63 | -9.79 | 53.85% | CHEMBL292759 | Active | 84.85% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.27 | -9.50 | N/A | 70.94% | CHEMBL1221452 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.69 | -9.37 | -9.02 | 53.85% | CHEMBL292759 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -9.21 | -10.07 | N/A | 70.94% | CHEMBL1221452 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -9.17 | -8.96 | -8.44 | 42.01% | CHEMBL90559 | Inactive | 55.71% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.60 | -7.59 | -8.18 | 38.51% | CHEMBL538029 | Inactive | 70.41% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.57 | -9.18 | -10.05 | 70.94% | CHEMBL1221452 | Active | 95.15% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -9.43 | -9.75 | -9.67 | 56.59% | CHEMBL523519 | Active | 88.55% |
| AA1R_HUMAN | adenosine A1 receptor | -9.04 | -8.95 | -8.78 | 36.36% | CHEMBL1170137 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -8.56 | -8.57 | -8.91 | 37.70% | CHEMBL482648 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.91 | -8.93 | -8.90 | 38.02% | CHEMBL520899 | Active | 62.12% |
| AA3R_HUMAN | adenosine A3 receptor | -6.39 | -6.03 | -8.98 | 42.49% | CHEMBL603 | Active | 58.00% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.90 | -0.89 | N/A | 50.41% | CHEMBL1455766 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -8.75 | -8.30 | -8.46 | 50.41% | CHEMBL1713967 | Active | 58.42% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -9.95 | -10.42 | -9.52 | 53.57% | CHEMBL494778 | Active | 83.29% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.72 | -8.74 | N/A | 50.41% | CHEMBL1455766 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -10.41 | -10.35 | -10.20 | 50.00% | CHEMBL3329736 | Active | 89.01% |
| ACTHR_HUMAN | melanocortin 2 receptor | -9.50 | -9.88 | -8.40 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.51 | -8.64 | -8.49 | 46.58% | CHEMBL236830 | Active | 50.24% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -2.17 | 0.58 | 2.27 | 52.46% | CHEMBL1221499 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -9.78 | -8.23 | -8.97 | 31.41% | CHEMBL346389 | Active | 66.19% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 0.55 | 2.58 | 2.34 | 50.41% | CHEMBL1455766 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -8.98 | -8.83 | -9.25 | 56.55% | CHEMBL417250 | Active | 83.54% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -8.61 | -7.92 | -9.45 | 60.00% | CHEMBL1375364 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -9.52 | -9.10 | -9.49 | 56.55% | CHEMBL417250 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -9.29 | -9.24 | -9.13 | 37.21% | CHEMBL216515 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.32 | -10.37 | -10.94 | 38.27% | CHEMBL208738 | Inactive | 56.03% |
| CALCR_HUMAN | calcitonin receptor | -8.37 | -7.65 | -8.47 | 17.17% | CHEMBL2369897 | Inactive | 98.14% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.31 | -8.38 | -8.72 | 37.10% | CHEMBL217595 | Inactive | 87.79% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.45 | -7.37 | -8.35 | 45.77% | CHEMBL1171758 | Inactive | 67.18% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.78 | -9.29 | -8.10 | 45.77% | CHEMBL1171758 | Active | 54.03% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -8.12 | -7.89 | -8.37 | 42.48% | CHEMBL1171786 | Inactive | 65.07% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.68 | -8.52 | -8.63 | 42.48% | CHEMBL1171786 | Inactive | 85.07% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -7.79 | -8.90 | -10.03 | 44.25% | CHEMBL1214096 | Active | 65.33% |
| CNR1_HUMAN | cannabinoid receptor 1 | -9.22 | -10.55 | -10.79 | 100.00% | CHEMBL2336543 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -10.39 | -10.31 | N/A | 100.00% | CHEMBL2326297 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -3.13 | N/A | N/A | 37.34% | CHEMBL376540 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.90 | -7.29 | -7.56 | 37.34% | CHEMBL376540 | Inactive | 56.06% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.84 | -9.00 | -9.12 | 68.47% | CHEMBL1085258 | Active | 76.64% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.15 | -7.61 | -7.41 | 43.93% | CHEMBL4100900 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.57 | -8.74 | -8.82 | 45.21% | CHEMBL599487 | Active | 64.03% |
| DRD2_HUMAN | dopamine receptor D2 | -8.38 | N/A | N/A | 53.23% | CHEMBL231326 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.53 | N/A | N/A | 70.94% | CHEMBL1221452 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -9.62 | -9.82 | N/A | 46.38% | CHEMBL194755 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -8.72 | -10.00 | -8.90 | 47.71% | CHEMBL394110 | Active | 80.58% |
| EDNRA_HUMAN | endothelin receptor type A | -7.75 | -7.62 | -7.60 | 42.86% | CHEMBL266277 | Active | 63.00% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 4.03 | -2.55 | 21.68 | 16.96% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.12 | -9.13 | -7.23 | 43.93% | CHEMBL215416 | Inactive | 67.42% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -8.98 | -9.70 | -7.70 | 33.73% | CHEMBL3759211 | Inactive | 60.03% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -0.68 | 0.34 | -0.76 | 51.45% | CHEMBL421406 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -0.93 | -3.81 | -4.57 | 25.47% | CHEMBL3747073 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 2.51 | 3.32 | 1.93 | 55.47% | CHEMBL1921853 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -5.87 | -7.97 | -7.72 | 39.86% | CHEMBL4068775 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -2.90 | -6.19 | -3.31 | 22.50% | CHEMBL1585091 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | 0.46 | 1.96 | -0.97 | 28.95% | CHEMBL3560146 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -0.69 | 2.90 | 0.78 | 28.95% | CHEMBL3560146 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -6.56 | N/A | N/A | 50.41% | CHEMBL1455766 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.67 | -9.11 | -8.99 | 36.75% | CHEMBL321709 | Active | 98.59% |
| HRH3_HUMAN | histamine receptor H3 | -7.89 | -8.91 | -8.51 | 48.23% | CHEMBL2021983 | Active | 67.81% |
| HRH4_HUMAN | histamine receptor H4 | -8.57 | -8.93 | -8.70 | 33.82% | CHEMBL511 | Inactive | 64.56% |
| MC3R_HUMAN | melanocortin 3 receptor | -8.63 | -8.17 | -8.21 | 28.33% | CHEMBL467586 | Inactive | 73.15% |
| MC4R_HUMAN | melanocortin 4 receptor | -8.25 | -7.49 | -7.64 | 40.10% | CHEMBL1537104 | Inactive | 88.69% |
| MC5R_HUMAN | melanocortin 5 receptor | -7.21 | -9.76 | -4.22 | 35.64% | CHEMBL2113139 | Inactive | 99.99% |
| MSHR_HUMAN | melanocortin 1 receptor | -9.96 | -8.64 | -8.47 | 34.38% | CHEMBL429212 | Inactive | 77.27% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.76 | -8.72 | -8.51 | 39.87% | CHEMBL329007 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -8.79 | -8.20 | -8.52 | 32.43% | CHEMBL280789 | Inactive | 95.34% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -8.35 | -8.21 | -8.41 | 26.37% | CHEMBL1940354 | Inactive | 90.58% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.01 | -7.69 | -8.07 | 30.00% | CHEMBL3361420 | Inactive | 79.67% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -9.46 | -9.66 | -8.68 | 25.64% | CHEMBL1289780 | Inactive | 61.32% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.68 | -8.80 | -9.14 | 33.33% | CHEMBL2046862 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -7.80 | -8.45 | -8.08 | 47.33% | CHEMBL1427860 | Inactive | 90.10% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.64 | -8.39 | -8.13 | 21.95% | CHEMBL3559801 | Inactive | 74.29% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -7.88 | -7.42 | -7.57 | 49.28% | CHEMBL16965 | Inactive | 62.81% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.66 | -6.86 | -7.65 | 44.12% | CHEMBL401594 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.58 | -8.66 | -8.64 | 63.33% | CHEMBL1713635 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.96 | -7.64 | -7.91 | 54.48% | CHEMBL1712885 | Active | 51.45% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.51 | -7.33 | -7.70 | 39.71% | CHEMBL3942616 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.21 | -8.94 | -8.51 | 35.44% | CHEMBL418608 | Inactive | 53.88% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -9.27 | -9.82 | -9.43 | 48.18% | CHEMBL1558546 | Inactive | 63.64% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -9.94 | -9.77 | -9.67 | 31.11% | CHEMBL1719708 | Inactive | 95.04% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -8.48 | -8.52 | -8.71 | 52.74% | CHEMBL200682 | Active | 55.86% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.73 | -9.19 | -8.79 | 23.04% | CHEMBL1784685 | N/A | N/A |