| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.25 | -7.84 | -8.56 | 39.53% | CHEMBL340786 | Inactive | 50.69% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.36 | -8.83 | -9.01 | 39.53% | CHEMBL340786 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.38 | -7.76 | -7.49 | 39.53% | CHEMBL340786 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.72 | -7.98 | -9.11 | 28.50% | CHEMBL29410 | Inactive | 73.78% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -8.58 | -9.75 | -8.71 | 35.62% | CHEMBL184994 | Inactive | 51.91% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.83 | -8.89 | N/A | 39.41% | CHEMBL3409256 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -7.97 | -8.78 | -9.28 | 39.04% | CHEMBL209324 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.16 | -8.81 | N/A | 38.41% | CHEMBL1642865 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -9.01 | -9.69 | -8.04 | 34.39% | CHEMBL180680 | Inactive | 60.12% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.14 | -8.26 | -8.39 | 30.91% | CHEMBL3326993 | Inactive | 66.67% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.11 | -7.93 | -8.62 | 40.38% | CHEMBL3409260 | Active | 59.08% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.74 | -8.39 | -8.91 | 39.41% | CHEMBL3409256 | Active | 55.14% |
| AA1R_HUMAN | adenosine A1 receptor | -8.03 | -7.80 | -7.70 | 33.04% | CHEMBL1760901 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -7.62 | -7.97 | -7.19 | 34.12% | CHEMBL201042 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -9.19 | -8.63 | -7.90 | 34.12% | CHEMBL201042 | Inactive | 69.74% |
| AA3R_HUMAN | adenosine A3 receptor | -0.54 | -3.14 | -6.04 | 36.59% | CHEMBL24 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -6.96 | 11.34 | N/A | 37.08% | CHEMBL2057512 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.36 | -8.75 | -7.78 | 41.35% | CHEMBL82859 | Active | 56.04% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -7.98 | -8.83 | -9.41 | 41.35% | CHEMBL82859 | Inactive | 51.07% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.21 | -7.59 | N/A | 35.42% | CHEMBL71531 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -8.71 | -8.88 | -9.95 | 41.25% | CHEMBL3184335 | Active | 72.42% |
| ACTHR_HUMAN | melanocortin 2 receptor | -8.41 | -7.88 | -6.87 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.24 | -6.75 | -8.36 | 38.58% | CHEMBL142635 | Inactive | 67.18% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | 17.84 | ? | ? | ? | ? | ? | ? |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -9.48 | -8.04 | -8.03 | 34.75% | CHEMBL518592 | Active | 55.33% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 15.32 | ? | ? | ? | ? | ? | ? |
| ADRB1_HUMAN | adrenoceptor beta 1 | -8.56 | -8.28 | -8.93 | 50.34% | CHEMBL12943 | Active | 60.53% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -8.68 | -9.20 | -9.43 | 50.34% | CHEMBL12943 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -8.21 | -9.15 | -8.15 | 50.34% | CHEMBL12943 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -8.38 | -8.63 | -8.40 | 28.04% | CHEMBL215160 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.36 | -9.28 | -9.00 | 34.10% | CHEMBL280869 | Inactive | 71.59% |
| CALCR_HUMAN | calcitonin receptor | -7.03 | -7.84 | -8.20 | 27.11% | CHEMBL2369905 | Inactive | 98.12% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.06 | -7.86 | -9.01 | 35.03% | CHEMBL357983 | Inactive | 93.05% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.73 | -7.71 | -7.45 | 39.60% | CHEMBL2208416 | Inactive | 93.22% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.02 | -7.34 | -8.03 | 37.14% | CHEMBL246313 | Inactive | 90.54% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.09 | -7.74 | -8.61 | 31.28% | CHEMBL64391 | Inactive | 72.48% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.72 | -7.86 | -7.38 | 40.69% | CHEMBL370552 | Inactive | 95.86% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.62 | -9.34 | -8.99 | 38.69% | CHEMBL3342949 | Inactive | 85.60% |
| CNR1_HUMAN | cannabinoid receptor 1 | -8.43 | -8.90 | -8.47 | 43.37% | CHEMBL410337 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -10.01 | -9.14 | N/A | 42.14% | CHEMBL466402 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | 7.41 | N/A | N/A | 31.44% | CHEMBL3426944 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.28 | -8.15 | -7.26 | 38.24% | CHEMBL3927944 | Inactive | 59.73% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.36 | -8.03 | -8.09 | 37.04% | CHEMBL3949577 | Inactive | 94.72% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.89 | -7.32 | -7.34 | 30.57% | CHEMBL4100900 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -8.83 | -7.74 | -8.22 | 35.93% | CHEMBL1112 | Active | 54.42% |
| DRD2_HUMAN | dopamine receptor D2 | -7.43 | N/A | N/A | 41.45% | CHEMBL2165124 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.49 | N/A | N/A | 41.29% | CHEMBL1813585 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -9.00 | -9.08 | N/A | 41.29% | CHEMBL1813585 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -8.48 | -9.77 | -8.90 | 37.16% | CHEMBL394080 | Inactive | 57.77% |
| EDNRA_HUMAN | endothelin receptor type A | -7.22 | -7.88 | -7.53 | 34.54% | CHEMBL330629 | Inactive | 60.06% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | ? | ? | ? | ? | ? | ? | ? |
| GASR_HUMAN | cholecystokinin B receptor | -7.55 | -7.88 | -7.01 | 35.15% | CHEMBL217424 | Inactive | 81.62% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.79 | -9.19 | 3.14 | 30.57% | CHEMBL507522 | Inactive | 99.99% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | 10.43 | 8.86 | 10.84 | 43.66% | CHEMBL1098389 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | 0.00 | 2.28 | -5.70 | 32.12% | CHEMBL1630807 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 8.70 | 5.93 | ? | ? | ? | ? | ? |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -9.46 | -4.95 | -7.67 | 36.71% | CHEMBL206427 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -1.41 | -1.66 | 5.09 | 31.22% | CHEMBL1585091 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | 13.55 | 0.93 | -1.68 | 40.64% | CHEMBL3560393 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 14.71 | 4.42 | ? | ? | ? | ? | ? |
| HRH1_HUMAN | histamine receptor H1 | -6.71 | N/A | N/A | 40.58% | CHEMBL2158830 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -10.07 | -7.98 | -9.05 | 33.14% | CHEMBL107293 | Active | 96.21% |
| HRH3_HUMAN | histamine receptor H3 | -8.58 | -8.80 | -7.63 | 48.37% | CHEMBL240187 | Active | 74.09% |
| HRH4_HUMAN | histamine receptor H4 | -8.76 | -8.61 | -8.87 | 30.86% | CHEMBL1202325 | Inactive | 68.18% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.69 | -7.46 | -7.59 | 34.48% | CHEMBL467586 | Inactive | 67.87% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.10 | -7.24 | -6.36 | 41.62% | CHEMBL1200485 | Inactive | 88.79% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.72 | -8.33 | -6.28 | 34.48% | CHEMBL467586 | Inactive | 59.54% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.40 | -7.21 | -7.91 | 33.00% | CHEMBL591037 | Inactive | 64.90% |
| NK1R_HUMAN | tachykinin receptor 1 | -7.76 | -8.00 | -7.33 | 38.30% | CHEMBL162332 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -8.49 | -8.56 | -7.92 | 33.14% | CHEMBL183414 | Inactive | 97.24% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -9.07 | -8.02 | -8.57 | 26.11% | CHEMBL1968640 | Inactive | 85.24% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -7.93 | -8.17 | -8.46 | 32.70% | CHEMBL3361420 | Inactive | 60.03% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -8.30 | -9.59 | -9.18 | 29.56% | CHEMBL1801361 | Inactive | 69.79% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -8.71 | -8.31 | -7.85 | 34.00% | CHEMBL329997 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -7.93 | -7.95 | -7.85 | 38.61% | CHEMBL3104195 | Inactive | 96.45% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.09 | -9.02 | -8.48 | 29.66% | CHEMBL3559801 | Inactive | 91.32% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.09 | -7.26 | -7.36 | 39.84% | CHEMBL76661 | Inactive | 79.66% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.23 | -5.68 | -7.05 | 40.27% | CHEMBL2079638 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -8.77 | -7.70 | -8.09 | 36.36% | CHEMBL1258503 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.04 | -6.57 | -7.43 | 36.36% | CHEMBL1258503 | Inactive | 82.82% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.68 | -7.73 | -7.75 | 35.50% | CHEMBL2064132 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.29 | -8.40 | -7.99 | 31.25% | CHEMBL54106 | Inactive | 69.87% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -9.10 | -8.93 | -8.59 | 47.90% | CHEMBL1490462 | Active | 51.78% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -8.03 | -8.26 | -8.82 | 37.58% | CHEMBL3913851 | Inactive | 89.49% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -8.56 | -8.05 | -8.10 | 40.13% | CHEMBL3416769 | Inactive | 70.63% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -7.81 | -7.68 | -8.97 | 25.11% | CHEMBL524852 | N/A | N/A |