| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -6.03 | -5.84 | -5.96 | 52.83% | CHEMBL129661 | Active | 72.22% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -6.67 | -6.64 | -5.91 | 52.83% | CHEMBL129661 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -6.23 | -6.00 | -6.71 | 52.83% | CHEMBL129661 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -6.56 | -6.21 | -6.43 | 25.00% | CHEMBL39 | Inactive | 66.29% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -6.72 | -5.71 | -6.13 | 32.17% | CHEMBL184994 | Inactive | 71.37% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -6.12 | -6.18 | N/A | 48.94% | CHEMBL277120 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -6.01 | -5.91 | -6.02 | 44.62% | CHEMBL57135 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -6.24 | -6.31 | N/A | 44.62% | CHEMBL57135 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -6.23 | -6.25 | -6.18 | 28.83% | CHEMBL339936 | Inactive | 65.12% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -6.04 | -6.23 | -6.18 | 63.83% | CHEMBL24462 | Active | 87.85% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -5.85 | -5.65 | -5.79 | 49.12% | CHEMBL9666 | Inactive | 57.86% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -6.09 | -5.98 | -5.77 | 54.90% | CHEMBL3262404 | Active | 88.96% |
| AA1R_HUMAN | adenosine A1 receptor | -5.56 | -5.73 | -5.75 | 36.27% | CHEMBL1814055 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -5.97 | -5.95 | -5.88 | 36.27% | CHEMBL1814055 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -5.72 | -6.33 | -5.94 | 36.27% | CHEMBL1814055 | Active | 56.42% |
| AA3R_HUMAN | adenosine A3 receptor | -6.30 | -6.15 | -5.74 | 36.27% | CHEMBL1814055 | Active | 54.31% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -6.40 | -7.19 | N/A | 37.63% | CHEMBL1092460 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -6.08 | -6.00 | -6.28 | 46.25% | CHEMBL83982 | Active | 75.69% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -5.70 | -6.49 | -6.33 | 46.25% | CHEMBL83982 | Inactive | 52.02% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -6.42 | -5.80 | N/A | 34.09% | CHEMBL7568 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -6.39 | -6.22 | -6.28 | 33.33% | CHEMBL3354078 | Inactive | 69.75% |
| ACTHR_HUMAN | melanocortin 2 receptor | -7.34 | -6.61 | -5.72 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -5.61 | -6.22 | -5.61 | 42.25% | CHEMBL114669 | Active | 68.87% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -6.34 | -6.29 | -5.76 | 44.83% | CHEMBL3289540 | Active | 67.80% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -6.48 | -6.56 | -6.45 | 34.09% | CHEMBL7568 | Active | 56.40% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -5.87 | -5.51 | -5.07 | 46.00% | CHEMBL1879790 | Active | 67.21% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -5.95 | -6.04 | -6.04 | 41.18% | CHEMBL13102 | Active | 50.94% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.09 | -6.39 | -6.58 | 41.18% | CHEMBL13102 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -6.46 | -6.74 | -6.43 | 41.18% | CHEMBL13102 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -5.86 | -6.03 | -5.90 | 29.00% | CHEMBL290829 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -6.21 | -6.75 | -6.20 | 26.73% | CHEMBL110652 | Inactive | 75.11% |
| CALCR_HUMAN | calcitonin receptor | -5.58 | -5.31 | -6.08 | 14.84% | CHEMBL2369895 | Active | 71.16% |
| CCKAR_HUMAN | cholecystokinin A receptor | -5.48 | -5.50 | -6.57 | 34.91% | CHEMBL443825 | Inactive | 96.61% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -5.77 | -6.29 | -5.25 | 32.41% | CHEMBL2208416 | Inactive | 98.64% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -5.21 | -5.27 | -5.35 | 35.63% | CHEMBL246520 | Inactive | 91.42% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -5.41 | -5.78 | -6.19 | 27.43% | CHEMBL600196 | Inactive | 79.05% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -5.56 | -5.34 | -5.33 | 36.99% | CHEMBL433635 | Inactive | 99.51% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -6.23 | -6.89 | -6.63 | 31.82% | CHEMBL129866 | Inactive | 97.40% |
| CNR1_HUMAN | cannabinoid receptor 1 | -5.92 | -6.14 | -6.28 | 49.33% | CHEMBL200094 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -6.16 | -6.08 | N/A | 41.82% | CHEMBL2336559 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.41 | N/A | N/A | 50.79% | CHEMBL184637 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -5.85 | -5.40 | -5.24 | 44.12% | CHEMBL25573 | Inactive | 61.20% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -6.09 | -6.11 | -6.06 | 32.38% | CHEMBL245271 | Inactive | 98.87% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -6.73 | -5.63 | -5.82 | 29.33% | CHEMBL2347630 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -6.12 | -5.93 | -5.67 | 35.56% | CHEMBL25236 | Inactive | 63.56% |
| DRD2_HUMAN | dopamine receptor D2 | -6.47 | N/A | N/A | 50.91% | CHEMBL447809 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -6.05 | N/A | N/A | 49.12% | CHEMBL2165674 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -6.38 | -6.37 | N/A | 55.22% | CHEMBL184772 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -6.05 | -6.17 | -6.24 | 33.98% | CHEMBL394080 | Inactive | 86.45% |
| EDNRA_HUMAN | endothelin receptor type A | -5.10 | -6.79 | -5.14 | 25.55% | CHEMBL10905 | Inactive | 87.63% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -6.03 | -6.39 | -6.68 | 13.68% | CHEMBL392394 | Inactive | 90.79% |
| GASR_HUMAN | cholecystokinin B receptor | -5.96 | -6.00 | -5.64 | 34.91% | CHEMBL443825 | Inactive | 91.03% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -6.73 | -6.42 | -6.29 | 32.53% | CHEMBL254575 | Inactive | 81.84% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -6.32 | -6.70 | -6.60 | 32.95% | CHEMBL468800 | Inactive | 73.86% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -7.08 | -7.23 | -6.84 | 24.18% | CHEMBL1630807 | Inactive | 70.58% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -5.05 | -5.03 | -4.88 | 39.77% | CHEMBL3609733 | Inactive | 92.11% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.77 | -6.97 | -7.16 | 41.18% | CHEMBL1080481 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -6.32 | -6.31 | -6.33 | 23.23% | CHEMBL2418359 | Inactive | 95.10% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.33 | -5.94 | -6.71 | 26.24% | CHEMBL3560612 | Inactive | 99.88% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -5.66 | -5.92 | -5.88 | 26.24% | CHEMBL3560612 | Inactive | 98.63% |
| HRH1_HUMAN | histamine receptor H1 | -6.90 | N/A | N/A | 40.58% | CHEMBL1940414 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -7.18 | -6.39 | -7.30 | 30.17% | CHEMBL194837 | Active | 82.87% |
| HRH3_HUMAN | histamine receptor H3 | -5.73 | -5.50 | -5.81 | 47.89% | CHEMBL2387297 | Active | 93.52% |
| HRH4_HUMAN | histamine receptor H4 | -5.86 | -5.73 | -5.83 | 30.53% | CHEMBL128958 | Inactive | 50.11% |
| MC3R_HUMAN | melanocortin 3 receptor | -6.05 | -5.47 | -5.71 | 25.37% | CHEMBL377231 | Inactive | 74.23% |
| MC4R_HUMAN | melanocortin 4 receptor | -4.76 | -5.20 | -4.81 | 39.71% | CHEMBL1728670 | Inactive | 78.06% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.80 | -6.52 | -5.43 | 26.05% | CHEMBL3896315 | Inactive | 74.19% |
| MSHR_HUMAN | melanocortin 1 receptor | -6.51 | -5.30 | -6.63 | 24.18% | CHEMBL606399 | Inactive | 64.53% |
| NK1R_HUMAN | tachykinin receptor 1 | -5.62 | -6.00 | -5.77 | 37.97% | CHEMBL40262 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -5.89 | -5.54 | -5.83 | 28.70% | CHEMBL303119 | Inactive | 99.35% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -5.50 | -5.17 | -5.34 | 23.49% | CHEMBL1987717 | Inactive | 89.63% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -5.20 | -5.34 | -5.64 | 28.07% | CHEMBL3361420 | Inactive | 57.49% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -5.59 | -6.11 | -6.10 | 30.10% | CHEMBL1289780 | Inactive | 84.79% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -6.57 | -6.52 | -5.70 | 30.43% | CHEMBL2046861 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -5.57 | -5.31 | -5.34 | 35.71% | CHEMBL1287954 | Inactive | 52.31% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -6.08 | -5.67 | -5.46 | 19.09% | CHEMBL2440199 | Active | 94.31% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -5.89 | -6.09 | -6.07 | 51.52% | CHEMBL77355 | Inactive | 71.34% |
| OPRD_HUMAN | opioid receptor delta 1 | -5.63 | -4.77 | -5.46 | 43.04% | CHEMBL416930 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -5.65 | -6.23 | -6.55 | 41.18% | CHEMBL283552 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -5.81 | -5.17 | -5.59 | 46.88% | CHEMBL371268 | Inactive | 79.44% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -5.31 | -5.57 | -5.43 | 38.96% | CHEMBL3665425 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -6.15 | -6.04 | -5.98 | 31.82% | CHEMBL54106 | Inactive | 77.02% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -6.25 | -6.44 | -5.82 | 40.68% | CHEMBL1445005 | Active | 77.40% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -5.86 | -6.18 | -5.97 | 30.19% | CHEMBL3911383 | Inactive | 90.32% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -6.32 | -5.53 | -6.57 | 33.71% | CHEMBL106229 | Inactive | 93.74% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -5.57 | -5.81 | -5.52 | 17.69% | CHEMBL1784685 | N/A | N/A |