| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -7.36 | -6.53 | -6.16 | 51.72% | CHEMBL178680 | Inactive | 53.17% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -6.85 | -6.73 | -7.35 | 47.44% | CHEMBL146942 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -6.76 | -6.96 | -5.70 | 46.09% | CHEMBL100086 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -6.72 | -7.26 | -7.13 | 28.32% | CHEMBL2391541 | Inactive | 53.90% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -6.99 | -6.90 | -7.09 | 28.78% | CHEMBL3616488 | Inactive | 68.72% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -7.23 | -7.29 | N/A | 56.94% | CHEMBL493129 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -6.74 | -7.38 | -7.38 | 56.94% | CHEMBL493129 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -7.00 | -7.13 | N/A | 56.94% | CHEMBL493129 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -8.02 | -8.31 | -7.46 | 41.07% | CHEMBL80015 | Inactive | 61.45% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -7.15 | -6.00 | -6.58 | 44.33% | CHEMBL278751 | Active | 56.89% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -6.35 | -6.80 | -7.02 | 47.44% | CHEMBL146942 | Active | 59.48% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -7.47 | -7.29 | -7.50 | 47.44% | CHEMBL146942 | Active | 62.14% |
| AA1R_HUMAN | adenosine A1 receptor | -7.42 | -6.72 | -6.74 | 47.42% | CHEMBL1544 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -6.51 | -7.09 | -7.44 | 36.00% | CHEMBL2042091 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -7.77 | -7.51 | -6.88 | 31.37% | CHEMBL3317576 | Inactive | 57.60% |
| AA3R_HUMAN | adenosine A3 receptor | -7.52 | -7.93 | -7.01 | 43.27% | CHEMBL513389 | Active | 61.08% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.70 | -8.21 | N/A | 51.35% | CHEMBL4081662 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -7.49 | -6.50 | -7.58 | 52.04% | CHEMBL74305 | Active | 54.19% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -6.70 | -7.77 | -7.91 | 51.35% | CHEMBL4081662 | Active | 53.86% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -7.52 | -6.86 | N/A | 45.65% | CHEMBL24369 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -7.66 | -7.43 | -7.63 | 47.37% | CHEMBL3629534 | Active | 72.19% |
| ACTHR_HUMAN | melanocortin 2 receptor | -8.66 | -8.48 | -7.38 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -7.11 | -6.84 | -6.50 | 46.23% | CHEMBL385371 | Active | 63.20% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -7.36 | -7.25 | -6.01 | 50.00% | CHEMBL6966 | Active | 84.84% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -8.13 | -8.38 | -8.25 | 45.05% | CHEMBL3735756 | Active | 79.05% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -5.72 | -4.93 | -4.28 | 45.05% | CHEMBL3735756 | Active | 51.15% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -7.51 | -6.85 | -7.45 | 49.44% | CHEMBL768 | Active | 62.17% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -7.37 | -7.64 | -7.81 | 47.78% | CHEMBL3099663 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -7.81 | -8.56 | -7.69 | 45.87% | CHEMBL1201237 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -7.23 | -7.13 | -5.88 | 36.94% | CHEMBL154057 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -7.41 | -8.05 | -7.46 | 28.92% | CHEMBL2105864 | Inactive | 87.19% |
| CALCR_HUMAN | calcitonin receptor | -6.43 | -6.35 | -6.16 | 29.30% | CHEMBL2369895 | Inactive | 88.04% |
| CCKAR_HUMAN | cholecystokinin A receptor | -6.69 | -6.51 | -6.99 | 30.87% | CHEMBL382051 | Inactive | 91.87% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -6.80 | -6.93 | -6.38 | 43.52% | CHEMBL143690 | Inactive | 97.98% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -6.95 | -7.02 | -6.31 | 44.09% | CHEMBL3753178 | Inactive | 97.26% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -6.39 | -6.82 | -7.31 | 29.82% | CHEMBL1621896 | Inactive | 83.55% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -6.87 | -6.77 | -6.96 | 44.12% | CHEMBL182682 | Inactive | 95.05% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -7.79 | -8.22 | -8.57 | 35.45% | CHEMBL22776 | Inactive | 91.98% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.80 | -7.32 | -7.71 | 62.64% | CHEMBL947 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -7.52 | -7.80 | N/A | 66.67% | CHEMBL1923764 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.98 | N/A | N/A | 26.55% | CHEMBL522959 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -7.21 | -6.20 | -5.46 | 39.67% | CHEMBL3645131 | Inactive | 53.93% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -7.21 | -7.10 | -7.43 | 42.64% | CHEMBL3700578 | Inactive | 97.52% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -6.81 | -6.19 | -6.04 | 34.95% | CHEMBL126657 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -7.16 | -6.85 | -7.26 | 50.57% | CHEMBL3800636 | Inactive | 51.81% |
| DRD2_HUMAN | dopamine receptor D2 | -6.54 | N/A | N/A | 52.04% | CHEMBL330865 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -7.61 | N/A | N/A | 51.40% | CHEMBL3664834 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -7.78 | -7.63 | N/A | 50.57% | CHEMBL3800636 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -7.40 | -8.02 | -7.95 | 46.07% | CHEMBL231171 | Active | 64.50% |
| EDNRA_HUMAN | endothelin receptor type A | -5.46 | -6.31 | -6.14 | 60.00% | CHEMBL38537 | Inactive | 52.51% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -6.03 | -6.59 | -6.33 | 19.85% | CHEMBL2391908 | Inactive | 89.80% |
| GASR_HUMAN | cholecystokinin B receptor | -6.23 | -6.86 | -5.15 | 37.29% | CHEMBL1171596 | Inactive | 87.76% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.61 | -8.12 | -7.86 | 49.43% | CHEMBL254372 | Inactive | 50.66% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -6.26 | -7.06 | -6.53 | 68.75% | CHEMBL341457 | Active | 91.89% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -8.24 | -8.60 | -8.38 | 68.75% | CHEMBL341457 | Active | 86.39% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -4.94 | -5.58 | -5.46 | 25.13% | CHEMBL2063423 | Inactive | 97.48% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.94 | -8.53 | -8.62 | 42.00% | CHEMBL1682820 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -6.86 | -7.73 | -7.02 | 22.08% | CHEMBL280563 | Inactive | 98.41% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.92 | -6.22 | -6.49 | 49.00% | CHEMBL432038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -5.50 | -5.55 | -5.31 | 49.00% | CHEMBL432038 | Inactive | 96.70% |
| HRH1_HUMAN | histamine receptor H1 | -7.68 | N/A | N/A | 54.44% | CHEMBL59798 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -8.17 | -6.77 | -8.03 | 44.21% | CHEMBL2205811 | Active | 94.28% |
| HRH3_HUMAN | histamine receptor H3 | -7.23 | -6.37 | -6.41 | 56.32% | CHEMBL1824229 | Active | 92.31% |
| HRH4_HUMAN | histamine receptor H4 | -7.37 | -7.20 | -7.51 | 42.45% | CHEMBL14638 | Active | 76.99% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.03 | -6.26 | -6.55 | 35.62% | CHEMBL192450 | Inactive | 66.51% |
| MC4R_HUMAN | melanocortin 4 receptor | -5.56 | -6.40 | -6.02 | 38.00% | CHEMBL225856 | Inactive | 65.10% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.20 | -7.17 | -5.85 | 35.11% | CHEMBL363019 | Inactive | 62.22% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.42 | -6.79 | -7.61 | 35.16% | CHEMBL3951584 | Inactive | 63.79% |
| NK1R_HUMAN | tachykinin receptor 1 | -6.80 | -7.22 | -6.50 | 43.93% | CHEMBL1817892 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -6.20 | -6.77 | -5.92 | 39.60% | CHEMBL1083974 | Inactive | 98.33% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -5.83 | -5.56 | -6.74 | 33.54% | CHEMBL2001553 | Inactive | 92.19% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -6.09 | -6.20 | -6.44 | 31.62% | CHEMBL2208334 | Inactive | 79.58% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -6.16 | -7.52 | -7.00 | 31.74% | CHEMBL1801360 | Inactive | 78.37% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -7.78 | -7.08 | -6.81 | 50.67% | CHEMBL3559801 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -6.32 | -6.54 | -6.35 | 50.67% | CHEMBL3559801 | Active | 57.78% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -6.83 | -6.78 | -6.02 | 50.67% | CHEMBL3559801 | Active | 96.37% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -6.30 | -6.46 | -6.79 | 51.61% | CHEMBL68467 | Inactive | 65.79% |
| OPRD_HUMAN | opioid receptor delta 1 | -6.27 | -5.65 | -5.95 | 57.65% | CHEMBL1237044 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -7.47 | -7.25 | -6.59 | 57.89% | CHEMBL2022021 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -7.08 | -6.32 | -6.47 | 55.10% | CHEMBL3976681 | Inactive | 73.25% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -6.44 | -5.52 | -6.52 | 46.51% | CHEMBL3919659 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -6.76 | -6.68 | -6.90 | 59.30% | CHEMBL297624 | Active | 73.02% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -7.94 | -7.59 | -7.44 | 47.66% | CHEMBL1379139 | Active | 81.21% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -6.63 | -7.80 | -6.81 | 27.21% | CHEMBL3913851 | Inactive | 94.26% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -6.44 | -6.21 | -7.39 | 36.44% | CHEMBL1807268 | Inactive | 95.12% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -6.85 | -7.15 | -7.36 | 25.14% | CHEMBL3884667 | N/A | N/A |