| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -6.06 | -5.89 | -6.23 | 44.07% | CHEMBL4648489 | Active | 53.41% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -6.66 | -6.61 | -6.57 | 52.27% | CHEMBL73281 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -6.42 | -6.26 | -6.91 | 52.27% | CHEMBL73281 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -6.39 | -6.76 | -6.52 | 26.14% | CHEMBL4092027 | Inactive | 58.40% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -6.42 | -6.72 | -6.59 | 26.14% | CHEMBL4092027 | Inactive | 75.82% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -6.84 | -6.41 | N/A | 65.00% | CHEMBL445747 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -7.01 | -6.64 | -7.01 | 70.00% | CHEMBL475643 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -6.93 | -6.77 | N/A | 70.00% | CHEMBL475643 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -7.06 | -7.01 | -6.76 | 27.16% | CHEMBL4567394 | Inactive | 64.11% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -6.40 | -6.32 | -6.32 | 31.82% | CHEMBL161507 | Inactive | 56.61% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -5.92 | -5.95 | -6.51 | 47.37% | CHEMBL17157 | Inactive | 57.22% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -6.19 | -6.63 | -6.20 | 44.68% | CHEMBL234885 | Active | 57.97% |
| AA1R_HUMAN | adenosine A1 receptor | -6.29 | -6.79 | -6.91 | 28.24% | CHEMBL103150 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -6.88 | -6.79 | -6.66 | 29.23% | CHEMBL496 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -6.08 | -6.18 | -5.75 | 22.92% | CHEMBL67949 | Inactive | 59.24% |
| AA3R_HUMAN | adenosine A3 receptor | -7.43 | -7.14 | -6.17 | 29.23% | CHEMBL496 | Active | 56.08% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -6.96 | -7.23 | N/A | 46.43% | CHEMBL936 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -6.63 | -6.15 | -6.80 | 46.43% | CHEMBL936 | Active | 58.58% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -5.62 | -6.55 | -6.80 | 46.43% | CHEMBL936 | Inactive | 52.65% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -6.98 | -6.92 | N/A | 46.43% | CHEMBL936 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -6.76 | -6.32 | -6.70 | 46.43% | CHEMBL936 | Inactive | 53.62% |
| ACTHR_HUMAN | melanocortin 2 receptor | -8.57 | -8.30 | -7.16 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -6.28 | -6.40 | -5.96 | 38.33% | CHEMBL926 | Active | 66.70% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -7.06 | -7.00 | -6.14 | 65.79% | CHEMBL61006 | Active | 95.10% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -7.31 | -7.42 | -7.10 | 44.68% | CHEMBL972 | Active | 68.84% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -6.96 | -6.04 | -6.42 | 47.37% | CHEMBL17157 | Active | 70.66% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -6.41 | -6.63 | -6.41 | 39.39% | CHEMBL566777 | Inactive | 56.62% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.89 | -7.07 | -7.03 | 41.94% | CHEMBL566992 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -7.02 | -7.43 | -7.03 | 38.46% | CHEMBL1437 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -6.63 | -6.78 | -6.46 | 25.49% | CHEMBL219840 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -6.43 | -6.72 | -6.63 | 30.30% | CHEMBL121565 | Inactive | 85.98% |
| CALCR_HUMAN | calcitonin receptor | -6.08 | -6.03 | -6.48 | 16.99% | CHEMBL4575327 | Inactive | 86.41% |
| CCKAR_HUMAN | cholecystokinin A receptor | -6.28 | -6.63 | -7.25 | 19.30% | CHEMBL1210154 | Inactive | 94.14% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.45 | -7.14 | -6.00 | 39.39% | CHEMBL140270 | Inactive | 98.61% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -6.44 | -6.20 | -5.95 | 37.84% | CHEMBL3752640 | Inactive | 99.11% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -5.39 | -6.00 | -6.81 | 21.18% | CHEMBL1623307 | Inactive | 83.09% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -6.30 | -6.51 | -6.27 | 47.37% | CHEMBL17157 | Inactive | 98.48% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -6.87 | -7.85 | -7.17 | 27.78% | CHEMBL22776 | Inactive | 91.94% |
| CNR1_HUMAN | cannabinoid receptor 1 | -6.47 | -6.92 | -7.01 | 53.85% | CHEMBL233182 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -6.97 | -6.90 | N/A | 71.05% | CHEMBL408777 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.61 | N/A | N/A | 36.51% | CHEMBL191413 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -6.88 | -5.27 | -5.29 | 36.51% | CHEMBL191413 | Inactive | 60.29% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -6.95 | -6.83 | -6.87 | 29.79% | CHEMBL3898146 | Inactive | 99.02% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.23 | -5.25 | -6.23 | 29.17% | CHEMBL4440964 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -6.73 | -6.40 | -6.30 | 39.13% | CHEMBL59 | Inactive | 64.75% |
| DRD2_HUMAN | dopamine receptor D2 | -6.89 | N/A | N/A | 47.37% | CHEMBL93101 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -7.03 | N/A | N/A | 50.00% | CHEMBL93234 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -6.46 | -6.70 | N/A | 42.62% | CHEMBL334989 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -6.98 | -6.86 | -6.66 | 39.13% | CHEMBL59 | Inactive | 88.60% |
| EDNRA_HUMAN | endothelin receptor type A | -5.00 | -5.19 | -6.52 | 37.31% | CHEMBL290026 | Inactive | 86.62% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -6.80 | -7.15 | -7.45 | 20.56% | CHEMBL2391908 | Inactive | 92.53% |
| GASR_HUMAN | cholecystokinin B receptor | -6.03 | -6.03 | -4.99 | 27.06% | CHEMBL38874 | Inactive | 92.14% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.18 | -7.04 | -7.16 | 35.21% | CHEMBL254372 | Inactive | 70.02% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -7.49 | -8.16 | -7.85 | 43.33% | CHEMBL124501 | Active | 66.39% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -8.40 | -8.44 | -8.09 | 43.33% | CHEMBL124501 | Active | 61.09% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -5.82 | -5.53 | -5.72 | 20.83% | CHEMBL4242079 | Inactive | 95.33% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.02 | -7.66 | -7.58 | 45.90% | CHEMBL1682794 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -7.34 | -7.42 | -7.27 | 14.88% | CHEMBL566136 | Inactive | 97.75% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.52 | -6.54 | -6.89 | 32.69% | CHEMBL1387826 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -6.39 | -6.64 | -6.26 | 34.78% | CHEMBL143210 | Inactive | 98.40% |
| HRH1_HUMAN | histamine receptor H1 | -7.33 | N/A | N/A | 51.92% | CHEMBL572034 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -7.85 | -6.77 | -7.64 | 37.29% | CHEMBL21731 | Active | 91.62% |
| HRH3_HUMAN | histamine receptor H3 | -6.37 | -6.05 | -6.26 | 46.94% | CHEMBL272140 | Active | 94.73% |
| HRH4_HUMAN | histamine receptor H4 | -6.34 | -5.85 | -6.19 | 37.33% | CHEMBL489493 | Active | 60.63% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.12 | -6.80 | -6.83 | 26.00% | CHEMBL272099 | Inactive | 77.60% |
| MC4R_HUMAN | melanocortin 4 receptor | -5.26 | -5.20 | -6.47 | 40.00% | CHEMBL195998 | Inactive | 59.98% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.71 | -6.71 | -5.32 | 23.53% | CHEMBL1093304 | Inactive | 78.84% |
| MSHR_HUMAN | melanocortin 1 receptor | -6.81 | -6.07 | -6.25 | 25.77% | CHEMBL1091631 | Inactive | 77.53% |
| NK1R_HUMAN | tachykinin receptor 1 | -6.43 | -6.66 | -6.18 | 45.61% | CHEMBL305274 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -6.64 | -6.61 | -6.55 | 47.37% | CHEMBL17157 | Inactive | 95.30% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -5.71 | -5.72 | -5.83 | 19.01% | CHEMBL2001338 | Inactive | 93.55% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -6.25 | -5.70 | -6.05 | 28.17% | CHEMBL575058 | Inactive | 67.19% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -6.11 | -7.18 | -6.23 | 25.27% | CHEMBL3086828 | Inactive | 86.11% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -6.90 | -6.46 | -5.90 | 36.21% | CHEMBL3559801 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -6.19 | -5.68 | -5.89 | 36.21% | CHEMBL3559801 | Active | 54.28% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -6.17 | -6.04 | -5.69 | 36.21% | CHEMBL3559801 | Active | 95.05% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -5.84 | -5.69 | -5.95 | 36.21% | CHEMBL3559801 | Inactive | 84.14% |
| OPRD_HUMAN | opioid receptor delta 1 | -6.11 | -5.44 | -5.84 | 45.61% | CHEMBL138036 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -6.89 | -6.58 | -6.94 | 45.61% | CHEMBL138036 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -6.57 | -5.42 | -5.78 | 45.61% | CHEMBL138036 | Inactive | 80.34% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -5.81 | -5.86 | -5.85 | 44.64% | CHEMBL3937167 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -7.33 | -7.39 | -7.45 | 33.77% | CHEMBL297624 | Inactive | 59.92% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -6.98 | -6.23 | -6.50 | 61.76% | CHEMBL612 | Active | 88.97% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -6.98 | -7.08 | -6.68 | 25.74% | CHEMBL3891546 | Inactive | 93.25% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -6.67 | -5.68 | -6.91 | 29.07% | CHEMBL1807264 | Inactive | 93.53% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -6.82 | -6.09 | -6.61 | 17.20% | CHEMBL483749 | N/A | N/A |