| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -9.07 | -8.36 | -9.49 | 51.06% | CHEMBL3104092 | Active | 70.19% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -10.02 | -10.28 | -10.02 | 51.06% | CHEMBL3104092 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.86 | -9.98 | -10.05 | 51.06% | CHEMBL3104092 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -9.44 | -8.16 | -9.44 | 35.50% | CHEMBL4092027 | Inactive | 64.80% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.31 | -10.13 | -9.68 | 41.57% | CHEMBL187928 | Inactive | 50.58% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -10.25 | -10.32 | N/A | 55.62% | CHEMBL592752 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -10.57 | -10.71 | -10.96 | 57.53% | CHEMBL1110 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -10.19 | -10.41 | N/A | 55.62% | CHEMBL592752 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -10.81 | -10.98 | -10.00 | 49.16% | CHEMBL4202791 | Inactive | 63.31% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -10.07 | -8.39 | -8.78 | 56.65% | CHEMBL129476 | Active | 52.07% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -9.99 | -9.98 | -10.16 | 56.14% | CHEMBL1783965 | Active | 91.85% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -9.57 | -9.51 | -9.54 | 55.62% | CHEMBL592752 | Active | 89.65% |
| AA1R_HUMAN | adenosine A1 receptor | -9.97 | -9.70 | -8.43 | 48.57% | CHEMBL371131 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -9.82 | -9.55 | -9.38 | 48.57% | CHEMBL371131 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -9.03 | -10.64 | -9.80 | 37.50% | CHEMBL469136 | Inactive | 58.95% |
| AA3R_HUMAN | adenosine A3 receptor | -3.73 | -5.99 | -7.59 | 41.60% | CHEMBL349191 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -7.64 | 11.36 | N/A | 54.86% | CHEMBL322251 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -10.98 | -9.86 | -8.82 | 54.86% | CHEMBL322251 | Active | 64.62% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -9.43 | -10.81 | -10.56 | 45.25% | CHEMBL148328 | Active | 61.44% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.63 | -8.34 | N/A | 46.52% | CHEMBL4062718 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -11.09 | -10.75 | -9.29 | 45.95% | CHEMBL3334991 | Active | 91.23% |
| ACTHR_HUMAN | melanocortin 2 receptor | -11.79 | -11.93 | -9.38 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -9.88 | -8.74 | -9.83 | 49.22% | CHEMBL3104093 | Active | 78.00% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -3.24 | -2.29 | 0.71 | 55.62% | CHEMBL592752 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -11.26 | -9.80 | -9.56 | 47.94% | CHEMBL3104091 | Active | 72.65% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -0.09 | 3.57 | 3.94 | 51.06% | CHEMBL3104092 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.98 | -10.25 | -10.40 | 42.86% | CHEMBL498304 | Inactive | 50.95% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -10.73 | -10.70 | -11.33 | 42.33% | CHEMBL236251 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -10.82 | -10.64 | -10.02 | 42.86% | CHEMBL498304 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -10.05 | -9.89 | -9.82 | 44.66% | CHEMBL2435833 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -10.51 | -10.69 | -10.47 | 38.91% | CHEMBL25751 | Inactive | 53.99% |
| CALCR_HUMAN | calcitonin receptor | -9.01 | -8.93 | -9.08 | 30.17% | CHEMBL4476595 | Inactive | 98.15% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.89 | -8.35 | -8.70 | 41.98% | CHEMBL2372623 | Inactive | 79.89% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.97 | -8.76 | -8.39 | 55.33% | CHEMBL2178572 | Active | 57.24% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.24 | -9.50 | -8.78 | 63.31% | CHEMBL2314058 | Active | 93.07% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -8.31 | -9.39 | -9.91 | 45.91% | CHEMBL2435852 | Active | 60.81% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -9.31 | -9.13 | -9.16 | 60.12% | CHEMBL595902 | Active | 80.24% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -9.77 | -10.64 | -10.34 | 39.47% | CHEMBL423333 | Inactive | 69.89% |
| CNR1_HUMAN | cannabinoid receptor 1 | -9.70 | -9.28 | -8.68 | 67.30% | CHEMBL1950342 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -10.67 | -10.18 | N/A | 61.58% | CHEMBL1950330 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -4.51 | N/A | N/A | 34.45% | CHEMBL3609013 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -9.47 | -8.30 | -7.81 | 34.45% | CHEMBL3609013 | Inactive | 71.27% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -9.90 | -9.30 | -9.79 | 47.91% | CHEMBL395745 | Inactive | 56.16% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -9.21 | -7.52 | -8.42 | 51.21% | CHEMBL565749 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.91 | -9.68 | -9.87 | 49.71% | CHEMBL1086789 | Active | 85.82% |
| DRD2_HUMAN | dopamine receptor D2 | -10.64 | N/A | N/A | 55.62% | CHEMBL592752 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -10.91 | N/A | N/A | 51.52% | CHEMBL85606 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -10.07 | -9.84 | N/A | 50.85% | CHEMBL1771114 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -8.94 | -11.72 | -9.68 | 47.94% | CHEMBL3104091 | Inactive | 61.98% |
| EDNRA_HUMAN | endothelin receptor type A | -8.45 | -7.63 | -8.04 | 42.34% | CHEMBL3752680 | Active | 52.79% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 8.13 | -3.17 | 64.46 | 18.75% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -9.58 | -9.41 | -8.02 | 44.55% | CHEMBL282732 | Active | 59.19% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -9.81 | -10.14 | -8.80 | 38.89% | CHEMBL233709 | Inactive | 51.40% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -3.00 | -4.29 | 0.41 | 42.78% | CHEMBL3909273 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -6.24 | -7.13 | -8.86 | 44.55% | CHEMBL4559100 | Inactive | 88.79% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 0.94 | 4.79 | 3.01 | 41.15% | CHEMBL3797463 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -8.69 | -6.78 | -8.48 | 100.00% | CHEMBL1779871 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -6.11 | -8.79 | -3.10 | 35.81% | CHEMBL1585091 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -2.71 | -3.48 | -5.73 | 39.66% | CHEMBL4443735 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 2.01 | 2.16 | 8.74 | 37.74% | CHEMBL3560146 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -9.94 | N/A | N/A | 56.14% | CHEMBL1783965 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -10.50 | -9.14 | -10.23 | 49.22% | CHEMBL3104093 | Active | 98.21% |
| HRH3_HUMAN | histamine receptor H3 | -9.26 | -9.30 | -9.05 | 51.50% | CHEMBL2031865 | Active | 73.11% |
| HRH4_HUMAN | histamine receptor H4 | -9.94 | -9.18 | -9.98 | 41.38% | CHEMBL2047446 | Inactive | 54.82% |
| MC3R_HUMAN | melanocortin 3 receptor | -10.17 | -9.41 | -8.70 | 48.31% | CHEMBL463047 | Active | 63.00% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.94 | -7.68 | -9.27 | 48.31% | CHEMBL463047 | Active | 71.51% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.73 | -9.23 | -6.44 | 46.19% | CHEMBL183799 | Inactive | 69.28% |
| MSHR_HUMAN | melanocortin 1 receptor | -9.25 | -7.96 | -9.85 | 48.31% | CHEMBL463047 | Active | 50.61% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.74 | -9.52 | -9.13 | 50.90% | CHEMBL295122 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -9.86 | -9.99 | -10.45 | 49.72% | CHEMBL379097 | Active | 82.78% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -8.50 | -8.13 | -8.05 | 30.29% | CHEMBL1705499 | Inactive | 89.18% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -9.32 | -9.33 | -8.52 | 40.31% | CHEMBL2208312 | Inactive | 61.31% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -9.59 | -10.64 | -9.74 | 41.76% | CHEMBL1210177 | Active | 74.50% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -10.88 | -10.81 | -10.11 | 39.91% | CHEMBL124343 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -9.46 | -9.37 | -9.10 | 39.76% | CHEMBL437487 | Inactive | 55.60% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -9.07 | -9.65 | -9.32 | 34.98% | CHEMBL4641831 | Inactive | 99.28% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.46 | -9.18 | -8.75 | 43.09% | CHEMBL42437 | Inactive | 53.39% |
| OPRD_HUMAN | opioid receptor delta 1 | -9.02 | -6.49 | -8.25 | 55.74% | CHEMBL2347239 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -10.07 | -9.64 | -10.32 | 55.74% | CHEMBL2347239 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -9.34 | -8.02 | -8.63 | 55.74% | CHEMBL2347239 | Active | 55.59% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.79 | -8.74 | -8.81 | 55.32% | CHEMBL3349268 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -10.02 | -9.75 | -10.07 | 44.32% | CHEMBL294706 | Active | 63.91% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -9.69 | -10.15 | -9.99 | 59.28% | CHEMBL1872433 | Active | 68.48% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -10.64 | -10.74 | -10.28 | 36.22% | CHEMBL3983689 | Active | 54.26% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -9.30 | -9.73 | -9.68 | 49.17% | CHEMBL3416864 | Active | 57.90% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -10.13 | -8.76 | -10.22 | 31.50% | CHEMBL3736230 | N/A | N/A |