| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -6.12 | -6.18 | -6.41 | 44.87% | CHEMBL1255003 | Active | 59.89% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -5.93 | -6.16 | -6.49 | 43.48% | CHEMBL2112766 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -6.20 | -6.31 | -5.45 | 39.19% | CHEMBL140416 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -6.27 | -6.92 | -5.87 | 22.52% | CHEMBL2391541 | Inactive | 55.80% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -5.85 | -6.30 | -6.24 | 26.32% | CHEMBL184994 | Inactive | 79.34% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -6.45 | -6.45 | N/A | 43.42% | CHEMBL272942 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -6.36 | -6.53 | -6.65 | 44.62% | CHEMBL558 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -6.40 | -6.78 | N/A | 43.42% | CHEMBL272942 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -6.34 | -6.44 | -6.75 | 45.92% | CHEMBL287045 | Active | 56.07% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -6.41 | -6.16 | -6.27 | 30.09% | CHEMBL363678 | Inactive | 57.53% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -6.21 | -6.21 | -6.36 | 37.62% | CHEMBL631 | Inactive | 69.63% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -6.32 | -6.04 | -5.98 | 42.47% | CHEMBL20666 | Inactive | 54.77% |
| AA1R_HUMAN | adenosine A1 receptor | -5.58 | -5.62 | -6.41 | 32.77% | CHEMBL2151131 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -5.99 | -5.92 | -6.00 | 32.79% | CHEMBL197359 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -6.54 | -6.40 | -5.85 | 39.82% | CHEMBL334325 | Active | 62.47% |
| AA3R_HUMAN | adenosine A3 receptor | -6.62 | -6.49 | -6.06 | 32.77% | CHEMBL2151131 | Inactive | 52.82% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -6.75 | -6.89 | N/A | 40.26% | CHEMBL4102555 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -6.79 | -6.18 | -6.52 | 43.82% | CHEMBL1290634 | Active | 51.25% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -5.77 | -6.94 | -6.32 | 43.82% | CHEMBL1290634 | Inactive | 60.35% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -6.68 | -6.42 | N/A | 37.18% | CHEMBL55 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -6.35 | -6.36 | -6.39 | 33.70% | CHEMBL41 | Inactive | 64.96% |
| ACTHR_HUMAN | melanocortin 2 receptor | -6.96 | -6.30 | -6.16 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -6.07 | -6.36 | -5.88 | 44.87% | CHEMBL1255003 | Active | 77.93% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -7.03 | -7.00 | -6.93 | 39.22% | CHEMBL1956201 | Active | 78.69% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -6.86 | -7.47 | -6.97 | 39.22% | CHEMBL1956201 | Active | 77.29% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -6.35 | -6.47 | -6.40 | 39.22% | CHEMBL1956201 | Active | 70.27% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -6.53 | -6.14 | -6.38 | 52.17% | CHEMBL518168 | Active | 67.72% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.71 | -6.84 | -6.72 | 46.59% | CHEMBL1704973 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -6.91 | -7.33 | -6.87 | 53.93% | CHEMBL271945 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -5.94 | -6.11 | -6.00 | 26.25% | CHEMBL158557 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -6.71 | -6.75 | -6.41 | 28.57% | CHEMBL1784685 | Inactive | 85.19% |
| CALCR_HUMAN | calcitonin receptor | -5.94 | -5.23 | -6.42 | 15.82% | CHEMBL2369897 | Inactive | 52.72% |
| CCKAR_HUMAN | cholecystokinin A receptor | -5.69 | -6.35 | -5.91 | 28.57% | CHEMBL1784685 | Inactive | 95.77% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -5.93 | -7.33 | -5.89 | 41.03% | CHEMBL391301 | Inactive | 98.29% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -5.55 | -5.81 | -5.35 | 40.00% | CHEMBL1171788 | Inactive | 94.49% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -6.12 | -5.61 | -6.52 | 36.67% | CHEMBL1618631 | Inactive | 79.31% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -5.44 | -5.59 | -5.83 | 36.17% | CHEMBL234461 | Inactive | 99.10% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -6.29 | -6.77 | -6.98 | 39.58% | CHEMBL127842 | Inactive | 97.03% |
| CNR1_HUMAN | cannabinoid receptor 1 | -5.65 | -6.37 | -6.45 | 47.83% | CHEMBL243334 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -6.25 | -6.47 | N/A | 47.83% | CHEMBL243334 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.85 | N/A | N/A | 23.78% | CHEMBL464302 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -6.91 | -5.70 | -5.27 | 34.45% | CHEMBL3645131 | Inactive | 60.62% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -6.17 | -6.25 | -6.13 | 32.80% | CHEMBL3952475 | Inactive | 98.88% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -6.56 | -5.81 | -5.82 | 30.00% | CHEMBL126657 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -6.50 | -6.45 | -5.95 | 38.46% | CHEMBL186720 | Inactive | 60.06% |
| DRD2_HUMAN | dopamine receptor D2 | -5.97 | N/A | N/A | 40.26% | CHEMBL128313 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -6.08 | N/A | N/A | 39.24% | CHEMBL334545 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -7.02 | -6.67 | N/A | 42.86% | CHEMBL59326 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -6.16 | -7.04 | -6.63 | 38.46% | CHEMBL186720 | Inactive | 87.89% |
| EDNRA_HUMAN | endothelin receptor type A | -5.36 | -5.71 | -5.35 | 30.37% | CHEMBL46311 | Inactive | 95.45% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -6.37 | -6.78 | -6.75 | 14.07% | CHEMBL2391908 | Inactive | 91.22% |
| GASR_HUMAN | cholecystokinin B receptor | -6.03 | -6.43 | -5.76 | 24.14% | CHEMBL294542 | Inactive | 94.44% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -6.72 | -6.87 | -6.56 | 29.75% | CHEMBL369459 | Inactive | 79.05% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -7.16 | -7.16 | -7.43 | 39.81% | CHEMBL3892611 | Inactive | 59.83% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -7.54 | -8.08 | -7.66 | 30.77% | CHEMBL4099470 | Inactive | 69.22% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -5.34 | -5.74 | -5.37 | 29.66% | CHEMBL3560922 | Inactive | 92.84% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.61 | -7.52 | -7.37 | 51.65% | CHEMBL1682821 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -7.04 | -7.19 | -6.88 | 20.59% | CHEMBL566136 | Inactive | 97.67% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.46 | -6.16 | -6.56 | 29.66% | CHEMBL3560922 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -6.52 | -6.34 | -5.61 | 29.66% | CHEMBL3560922 | Inactive | 98.02% |
| HRH1_HUMAN | histamine receptor H1 | -7.17 | N/A | N/A | 38.46% | CHEMBL2158833 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -7.17 | -6.28 | -5.82 | 36.30% | CHEMBL221462 | Active | 80.50% |
| HRH3_HUMAN | histamine receptor H3 | -5.97 | -6.29 | -6.40 | 45.12% | CHEMBL544242 | Active | 81.81% |
| HRH4_HUMAN | histamine receptor H4 | -6.71 | -6.39 | -6.57 | 33.96% | CHEMBL14638 | Active | 58.62% |
| MC3R_HUMAN | melanocortin 3 receptor | -6.22 | -5.85 | -5.57 | 22.78% | CHEMBL392092 | Inactive | 64.68% |
| MC4R_HUMAN | melanocortin 4 receptor | -4.95 | -4.86 | -5.11 | 32.14% | CHEMBL205461 | Inactive | 90.23% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.33 | -6.42 | -5.56 | 28.47% | CHEMBL3932950 | Inactive | 64.40% |
| MSHR_HUMAN | melanocortin 1 receptor | -5.92 | -5.65 | -5.69 | 22.29% | CHEMBL13910 | Inactive | 84.13% |
| NK1R_HUMAN | tachykinin receptor 1 | -6.09 | -6.16 | -6.29 | 30.43% | CHEMBL93909 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -6.00 | -5.85 | -6.18 | 46.25% | CHEMBL4111499 | Inactive | 98.75% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -5.60 | -5.89 | -5.72 | 25.00% | CHEMBL1706758 | Inactive | 93.46% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -5.66 | -5.27 | -5.67 | 24.09% | CHEMBL2208334 | Inactive | 62.95% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -6.38 | -6.31 | -6.86 | 19.83% | CHEMBL3086828 | Inactive | 84.30% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -6.90 | -6.99 | -5.98 | 35.06% | CHEMBL3559801 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -6.24 | -5.83 | -5.72 | 35.06% | CHEMBL3559801 | Active | 54.76% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -6.15 | -5.71 | -5.87 | 35.06% | CHEMBL3559801 | Active | 95.25% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -6.18 | -6.25 | -6.21 | 35.06% | CHEMBL3559801 | Inactive | 87.19% |
| OPRD_HUMAN | opioid receptor delta 1 | -5.82 | -4.82 | -5.15 | 34.75% | CHEMBL149074 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -5.96 | -6.23 | -6.36 | 37.36% | CHEMBL942 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -6.59 | -6.54 | -6.61 | 34.75% | CHEMBL149074 | Inactive | 94.32% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -5.82 | -5.74 | -5.84 | 35.00% | CHEMBL201805 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -6.31 | -6.41 | -6.66 | 28.00% | CHEMBL297624 | Inactive | 81.10% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -6.88 | -6.62 | -6.64 | 40.00% | CHEMBL294703 | Active | 70.51% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -6.79 | -6.64 | -6.48 | 28.78% | CHEMBL1331194 | Inactive | 91.92% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -6.47 | -5.77 | -6.16 | 34.43% | CHEMBL3416859 | Inactive | 90.52% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -6.52 | -6.23 | -5.93 | 28.57% | CHEMBL1784685 | N/A | N/A |