| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.35 | -8.40 | -8.39 | 31.91% | CHEMBL50903 | Inactive | 68.91% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.73 | -8.74 | -9.14 | 33.04% | CHEMBL4064865 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.39 | -8.69 | -9.06 | 31.30% | CHEMBL329207 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -9.12 | -8.10 | -8.48 | 25.55% | CHEMBL103479 | Inactive | 75.36% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.53 | -9.33 | -8.91 | 28.83% | CHEMBL319920 | Inactive | 72.56% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.34 | -8.86 | N/A | 33.05% | CHEMBL297302 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -9.29 | -9.78 | -10.03 | 43.85% | CHEMBL3956531 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.93 | -9.16 | N/A | 43.85% | CHEMBL3956531 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -9.01 | -8.86 | -8.49 | 30.27% | CHEMBL2179582 | Inactive | 74.75% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.70 | -7.95 | -7.78 | 35.00% | CHEMBL3938006 | Inactive | 66.47% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.89 | -8.61 | -8.36 | 38.36% | CHEMBL1170890 | Active | 75.16% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.96 | -9.41 | -9.64 | 31.39% | CHEMBL182680 | Inactive | 51.24% |
| AA1R_HUMAN | adenosine A1 receptor | -8.83 | -9.05 | -8.02 | 51.46% | CHEMBL193421 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -8.46 | -8.74 | -8.45 | 52.40% | CHEMBL458346 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -9.14 | -9.08 | -9.15 | 43.57% | CHEMBL400189 | Active | 71.37% |
| AA3R_HUMAN | adenosine A3 receptor | -4.36 | -1.67 | -7.52 | 51.46% | CHEMBL193421 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.35 | 0.57 | N/A | 34.44% | CHEMBL4096143 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.77 | -8.65 | -7.46 | 34.44% | CHEMBL4096143 | Inactive | 56.52% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -9.21 | -10.43 | -8.84 | 34.44% | CHEMBL4096143 | Inactive | 59.11% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.10 | -8.59 | N/A | 35.34% | CHEMBL4094531 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -8.98 | -9.27 | -10.47 | 34.44% | CHEMBL4096143 | Active | 67.73% |
| ACTHR_HUMAN | melanocortin 2 receptor | -10.25 | -9.31 | -9.06 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.79 | -7.59 | -8.64 | 30.04% | CHEMBL511211 | Inactive | 67.18% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -0.60 | 2.60 | 4.51 | 30.88% | CHEMBL1306 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -9.74 | -8.12 | -8.14 | 28.09% | CHEMBL420060 | Active | 54.61% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 2.90 | 8.18 | 3.50 | 30.88% | CHEMBL1306 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.25 | -8.62 | -8.81 | 30.88% | CHEMBL515349 | Inactive | 68.36% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -8.48 | -8.37 | -10.01 | 36.11% | CHEMBL1325250 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -9.26 | -9.54 | -9.05 | 30.88% | CHEMBL515349 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -8.50 | -8.48 | -8.34 | 31.23% | CHEMBL288705 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.46 | -9.78 | -8.97 | 28.71% | CHEMBL413386 | Inactive | 76.47% |
| CALCR_HUMAN | calcitonin receptor | -7.90 | -8.42 | -8.38 | 25.16% | CHEMBL2369905 | Inactive | 98.60% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.48 | -9.09 | -8.61 | 28.38% | CHEMBL327656 | Inactive | 77.49% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.64 | -8.97 | -8.53 | 27.60% | CHEMBL308473 | Inactive | 74.60% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.64 | -7.55 | -7.39 | 32.58% | CHEMBL2338390 | Inactive | 69.22% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.94 | -7.79 | -8.54 | 36.22% | CHEMBL499852 | Inactive | 66.21% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.37 | -8.61 | -8.05 | 36.71% | CHEMBL342842 | Inactive | 92.42% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.35 | -9.46 | -9.25 | 28.47% | CHEMBL3401686 | Inactive | 84.08% |
| CNR1_HUMAN | cannabinoid receptor 1 | -8.26 | -9.19 | -8.85 | 37.40% | CHEMBL3353834 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -8.92 | -9.41 | N/A | 40.15% | CHEMBL3092887 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -0.46 | N/A | N/A | 25.95% | CHEMBL3906175 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.77 | -8.34 | -8.16 | 43.78% | CHEMBL257025 | Active | 70.43% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -9.06 | -9.06 | -9.03 | 34.66% | CHEMBL570919 | Inactive | 85.16% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.35 | -7.15 | -8.02 | 29.63% | CHEMBL3923006 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.32 | -8.79 | -8.75 | 31.18% | CHEMBL3099235 | Inactive | 56.81% |
| DRD2_HUMAN | dopamine receptor D2 | -8.00 | N/A | N/A | 35.91% | CHEMBL1258949 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.58 | N/A | N/A | 35.91% | CHEMBL1258949 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -9.71 | -10.25 | N/A | 35.14% | CHEMBL3318851 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -8.54 | -9.07 | -8.54 | 26.64% | CHEMBL3577346 | Inactive | 50.98% |
| EDNRA_HUMAN | endothelin receptor type A | -8.15 | -7.91 | -8.04 | 30.16% | CHEMBL2163697 | Inactive | 66.94% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 9.69 | 3.37 | 28.32 | 30.90% | CHEMBL392394 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.59 | -8.99 | -7.43 | 30.32% | CHEMBL2153191 | Inactive | 75.91% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -9.59 | -8.44 | -5.50 | 37.94% | CHEMBL3786530 | Inactive | 50.15% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | 6.82 | 6.22 | 8.34 | 33.69% | CHEMBL2206444 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | 0.70 | 1.42 | -2.19 | 30.69% | CHEMBL3948272 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 5.82 | 5.94 | 6.30 | 29.06% | CHEMBL4090015 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.92 | -4.14 | -3.02 | 34.30% | CHEMBL4072424 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -2.46 | -4.63 | -0.10 | 24.56% | CHEMBL1585091 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | 1.36 | 1.98 | -2.73 | 28.94% | CHEMBL3561038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 6.93 | 6.98 | 7.83 | 28.94% | CHEMBL3561038 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -7.84 | N/A | N/A | 34.81% | CHEMBL96141 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -10.22 | -8.77 | -9.31 | 27.80% | CHEMBL199824 | Active | 84.22% |
| HRH3_HUMAN | histamine receptor H3 | -8.38 | -8.75 | -8.90 | 30.15% | CHEMBL2441082 | Inactive | 58.73% |
| HRH4_HUMAN | histamine receptor H4 | -9.06 | -8.66 | -8.52 | 32.16% | CHEMBL1915533 | Inactive | 69.17% |
| MC3R_HUMAN | melanocortin 3 receptor | -8.92 | -8.51 | -8.10 | 34.68% | CHEMBL1089483 | Inactive | 64.43% |
| MC4R_HUMAN | melanocortin 4 receptor | -6.84 | -7.17 | -8.55 | 34.68% | CHEMBL1089483 | Inactive | 51.43% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.94 | -8.51 | -5.63 | 30.06% | CHEMBL2113039 | Inactive | 90.46% |
| MSHR_HUMAN | melanocortin 1 receptor | -8.31 | -7.71 | -9.45 | 30.77% | CHEMBL2113043 | Inactive | 62.78% |
| NK1R_HUMAN | tachykinin receptor 1 | -9.29 | -8.38 | -8.13 | 34.26% | CHEMBL214472 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -8.66 | -8.72 | -8.93 | 32.92% | CHEMBL3360201 | Inactive | 93.72% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -8.83 | -7.98 | -8.91 | 26.05% | CHEMBL1968640 | Inactive | 81.28% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.37 | -8.03 | -8.08 | 24.73% | CHEMBL2208301 | Inactive | 68.08% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -8.69 | -10.07 | -9.61 | 33.33% | CHEMBL1800088 | Inactive | 53.00% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -10.06 | -8.76 | -8.39 | 32.84% | CHEMBL347807 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.78 | -8.27 | -8.60 | 30.32% | CHEMBL3104112 | Inactive | 93.61% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -9.09 | -9.79 | -9.03 | 27.04% | CHEMBL3099722 | Inactive | 98.46% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.31 | -7.88 | -7.96 | 34.63% | CHEMBL595790 | Inactive | 82.51% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.99 | -7.37 | -7.61 | 32.54% | CHEMBL463518 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.99 | -8.51 | -9.01 | 41.25% | CHEMBL95302 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.95 | -8.26 | -8.48 | 36.30% | CHEMBL572393 | Inactive | 73.52% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.50 | -7.93 | -8.19 | 41.25% | CHEMBL95302 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -7.80 | -8.22 | -8.18 | 32.02% | CHEMBL37358 | Inactive | 65.84% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -8.80 | -8.84 | -9.33 | 54.81% | CHEMBL1466922 | Active | 60.50% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -9.25 | -9.90 | -8.65 | 26.67% | CHEMBL1718442 | Inactive | 96.59% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -8.55 | -9.02 | -8.99 | 30.54% | CHEMBL592732 | Inactive | 82.32% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.84 | -9.37 | -8.71 | 27.44% | CHEMBL3736134 | N/A | N/A |