| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||||
| Amodiaquine | GP160_HIV1 | Envelope glycoprotein gp160 | -5.91 | -5.79 | -7.63 | N/A | N/A |
| Cyclosporine | GP160_HIV1 | Envelope glycoprotein gp160 | -6.54 | -6.08 | -4.82 | N/A | N/A |
| Loperamide | GP160_HIV1 | Envelope glycoprotein gp160 | -6.93 | -6.82 | -6.62 | N/A | N/A |
| Tilorone | GP160_HIV1 | Envelope glycoprotein gp160 | -5.98 | -5.66 | -5.80 | N/A | N/A |
| Mefloquine | GP160_HIV1 | Envelope glycoprotein gp160 | -6.53 | -6.59 | -6.83 | N/A | N/A |
| Amodiaquine | GP160_HIV2 | Envelope glycoprotein gp160 | -6.30 | N/A | N/A | N/A | N/A |
| Cyclosporine | GP160_HIV2 | Envelope glycoprotein gp160 | -6.39 | N/A | N/A | N/A | N/A |
| Loperamide | GP160_HIV2 | Envelope glycoprotein gp160 | -7.02 | N/A | N/A | N/A | N/A |
| Tilorone | GP160_HIV2 | Envelope glycoprotein gp160 | -5.84 | N/A | N/A | N/A | N/A |
| Mefloquine | GP160_HIV2 | Envelope glycoprotein gp160 | -7.18 | N/A | N/A | N/A | N/A |
| Amodiaquine | GP_EBOV | Envelope glycoprotein | -7.07 | -7.05 | -7.28 | 18.82% | CHEMBL3125895 |
| Cyclosporine | GP_EBOV | Envelope glycoprotein | -3.52 | ? | ? | ? | ? |
| Loperamide | GP_EBOV | Envelope glycoprotein | -9.06 | -7.25 | -8.13 | 29.18% | CHEMBL3125895 |
| Tilorone | GP_EBOV | Envelope glycoprotein | -6.68 | -6.60 | -5.89 | 17.97% | CHEMBL3125895 |
| Mefloquine | GP_EBOV | Envelope glycoprotein | -7.04 | -7.66 | -7.52 | 35.74% | CHEMBL3125895 |
| Amodiaquine | HA_A-H10N7 | Hemagglutinin | -6.63 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H10N7 | Hemagglutinin | -3.04 | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H10N7 | Hemagglutinin | -7.65 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H10N7 | Hemagglutinin | -5.85 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H10N7 | Hemagglutinin | -7.21 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_A-H10N8 | Hemagglutinin | -6.08 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H10N8 | Hemagglutinin | 8.55 | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H10N8 | Hemagglutinin | -6.80 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H10N8 | Hemagglutinin | -5.38 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H10N8 | Hemagglutinin | -7.33 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_A-H13N6 | Hemagglutinin | -6.32 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H13N6 | Hemagglutinin | ? | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H13N6 | Hemagglutinin | -7.22 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H13N6 | Hemagglutinin | -5.78 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H13N6 | Hemagglutinin | -7.16 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_A-H14N6 | Hemagglutinin | -6.46 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H14N6 | Hemagglutinin | -3.25 | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H14N6 | Hemagglutinin | -7.60 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H14N6 | Hemagglutinin | -5.73 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H14N6 | Hemagglutinin | -6.30 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_A-H15N9 | Hemagglutinin | -6.31 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H15N9 | Hemagglutinin | -4.60 | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H15N9 | Hemagglutinin | -7.30 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H15N9 | Hemagglutinin | -5.71 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H15N9 | Hemagglutinin | -6.65 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_A-H17N10 | Hemagglutinin | -5.41 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H17N10 | Hemagglutinin | -6.24 | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H17N10 | Hemagglutinin | -6.11 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H17N10 | Hemagglutinin | -5.10 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H17N10 | Hemagglutinin | -6.53 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_A-H18N11 | Hemagglutinin | -5.29 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H18N11 | Hemagglutinin | -6.45 | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H18N11 | Hemagglutinin | -5.50 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H18N11 | Hemagglutinin | -4.95 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H18N11 | Hemagglutinin | -6.05 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_A-H1N1 | Hemagglutinin | -6.38 | -6.26 | N/A | N/A | N/A |
| Cyclosporine | HA_A-H1N1 | Hemagglutinin | -6.54 | -5.63 | N/A | N/A | N/A |
| Loperamide | HA_A-H1N1 | Hemagglutinin | -7.03 | -6.66 | N/A | N/A | N/A |
| Tilorone | HA_A-H1N1 | Hemagglutinin | -5.57 | -6.07 | N/A | N/A | N/A |
| Mefloquine | HA_A-H1N1 | Hemagglutinin | -6.91 | -6.93 | N/A | N/A | N/A |
| Amodiaquine | HA_A-H2N2 | Hemagglutinin | -6.44 | -5.87 | N/A | N/A | N/A |
| Cyclosporine | HA_A-H2N2 | Hemagglutinin | -6.97 | -7.03 | N/A | N/A | N/A |
| Loperamide | HA_A-H2N2 | Hemagglutinin | -6.63 | -6.18 | N/A | N/A | N/A |
| Tilorone | HA_A-H2N2 | Hemagglutinin | -5.62 | -4.86 | N/A | N/A | N/A |
| Mefloquine | HA_A-H2N2 | Hemagglutinin | -6.66 | -6.97 | N/A | N/A | N/A |
| Amodiaquine | HA_A-H3N2 | Hemagglutinin | -6.62 | -6.61 | -6.64 | N/A | N/A |
| Cyclosporine | HA_A-H3N2 | Hemagglutinin | -5.65 | -4.93 | ? | N/A | N/A |
| Loperamide | HA_A-H3N2 | Hemagglutinin | -6.82 | -6.50 | -6.84 | N/A | N/A |
| Tilorone | HA_A-H3N2 | Hemagglutinin | -5.99 | -5.79 | -5.61 | N/A | N/A |
| Mefloquine | HA_A-H3N2 | Hemagglutinin | -7.43 | -7.13 | -6.79 | N/A | N/A |
| Amodiaquine | HA_A-H3N8 | Hemagglutinin | -5.80 | -5.96 | -5.95 | N/A | N/A |
| Cyclosporine | HA_A-H3N8 | Hemagglutinin | -5.53 | -6.09 | -5.51 | N/A | N/A |
| Loperamide | HA_A-H3N8 | Hemagglutinin | -6.67 | -6.12 | -6.21 | N/A | N/A |
| Tilorone | HA_A-H3N8 | Hemagglutinin | -5.29 | -5.58 | -5.46 | N/A | N/A |
| Mefloquine | HA_A-H3N8 | Hemagglutinin | -5.93 | -6.38 | -6.34 | N/A | N/A |
| Amodiaquine | HA_A-H5N1 | Hemagglutinin | -6.15 | -6.03 | -5.91 | N/A | N/A |
| Cyclosporine | HA_A-H5N1 | Hemagglutinin | -5.77 | -5.01 | -0.78 | N/A | N/A |
| Loperamide | HA_A-H5N1 | Hemagglutinin | -6.78 | -6.41 | -6.75 | N/A | N/A |
| Tilorone | HA_A-H5N1 | Hemagglutinin | -5.41 | -6.38 | -5.75 | N/A | N/A |
| Mefloquine | HA_A-H5N1 | Hemagglutinin | -6.67 | -6.58 | -6.49 | N/A | N/A |
| Amodiaquine | HA_A-H5N3 | Hemagglutinin | -6.49 | -5.81 | N/A | N/A | N/A |
| Cyclosporine | HA_A-H5N3 | Hemagglutinin | -3.11 | ? | N/A | N/A | N/A |
| Loperamide | HA_A-H5N3 | Hemagglutinin | -6.68 | -6.55 | N/A | N/A | N/A |
| Tilorone | HA_A-H5N3 | Hemagglutinin | -5.87 | -5.81 | N/A | N/A | N/A |
| Mefloquine | HA_A-H5N3 | Hemagglutinin | -6.95 | -6.80 | N/A | N/A | N/A |
| Amodiaquine | HA_A-H6N1 | Hemagglutinin | -6.08 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H6N1 | Hemagglutinin | 8.55 | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H6N1 | Hemagglutinin | -6.80 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H6N1 | Hemagglutinin | -5.38 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H6N1 | Hemagglutinin | -7.33 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_A-H6N6 | Hemagglutinin | -6.03 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H6N6 | Hemagglutinin | -3.65 | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H6N6 | Hemagglutinin | -6.08 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H6N6 | Hemagglutinin | -5.09 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H6N6 | Hemagglutinin | -6.59 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_A-H7N2 | Hemagglutinin | -5.97 | -5.52 | -5.83 | N/A | N/A |
| Cyclosporine | HA_A-H7N2 | Hemagglutinin | -6.05 | ? | ? | N/A | N/A |
| Loperamide | HA_A-H7N2 | Hemagglutinin | -7.02 | -6.32 | -6.82 | N/A | N/A |
| Tilorone | HA_A-H7N2 | Hemagglutinin | -5.09 | -4.81 | -4.99 | N/A | N/A |
| Mefloquine | HA_A-H7N2 | Hemagglutinin | -6.72 | -5.79 | -6.63 | N/A | N/A |
| Amodiaquine | HA_A-H7N7 | Hemagglutinin | -6.13 | -6.72 | N/A | N/A | N/A |
| Cyclosporine | HA_A-H7N7 | Hemagglutinin | -6.44 | -5.56 | N/A | N/A | N/A |
| Loperamide | HA_A-H7N7 | Hemagglutinin | -6.05 | -6.91 | N/A | N/A | N/A |
| Tilorone | HA_A-H7N7 | Hemagglutinin | -4.81 | -6.23 | N/A | N/A | N/A |
| Mefloquine | HA_A-H7N7 | Hemagglutinin | -6.19 | -7.18 | N/A | N/A | N/A |
| Amodiaquine | HA_A-H7N9 | Hemagglutinin | -6.05 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_A-H7N9 | Hemagglutinin | -6.15 | N/A | N/A | N/A | N/A |
| Loperamide | HA_A-H7N9 | Hemagglutinin | -7.35 | N/A | N/A | N/A | N/A |
| Tilorone | HA_A-H7N9 | Hemagglutinin | -5.51 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_A-H7N9 | Hemagglutinin | -7.09 | N/A | N/A | N/A | N/A |
| Amodiaquine | HA_INFB | Hemagglutinin | -6.38 | -5.93 | N/A | N/A | N/A |
| Cyclosporine | HA_INFB | Hemagglutinin | -5.80 | -3.83 | N/A | N/A | N/A |
| Loperamide | HA_INFB | Hemagglutinin | -6.95 | -6.57 | N/A | N/A | N/A |
| Tilorone | HA_INFB | Hemagglutinin | -5.78 | -5.30 | N/A | N/A | N/A |
| Mefloquine | HA_INFB | Hemagglutinin | -6.95 | -6.93 | N/A | N/A | N/A |
| Amodiaquine | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -5.57 | N/A | N/A | N/A | N/A |
| Cyclosporine | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | ? | N/A | N/A | N/A | N/A |
| Loperamide | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -7.13 | N/A | N/A | N/A | N/A |
| Tilorone | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -5.96 | N/A | N/A | N/A | N/A |
| Mefloquine | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -7.29 | N/A | N/A | N/A | N/A |
| Amodiaquine | HE_BCV | Hemagglutinin-esterase | -6.15 | -5.76 | N/A | N/A | N/A |
| Cyclosporine | HE_BCV | Hemagglutinin-esterase | 64.78 | -3.79 | N/A | N/A | N/A |
| Loperamide | HE_BCV | Hemagglutinin-esterase | -6.79 | -6.68 | N/A | N/A | N/A |
| Tilorone | HE_BCV | Hemagglutinin-esterase | -5.44 | -5.44 | N/A | N/A | N/A |
| Mefloquine | HE_BCV | Hemagglutinin-esterase | -6.68 | -6.49 | N/A | N/A | N/A |
| Amodiaquine | HE_HCoV-OC43 | Hemagglutinin-esterase | -5.61 | N/A | N/A | N/A | N/A |
| Cyclosporine | HE_HCoV-OC43 | Hemagglutinin-esterase | -4.68 | N/A | N/A | N/A | N/A |
| Loperamide | HE_HCoV-OC43 | Hemagglutinin-esterase | -6.57 | N/A | N/A | N/A | N/A |
| Tilorone | HE_HCoV-OC43 | Hemagglutinin-esterase | -5.46 | N/A | N/A | N/A | N/A |
| Mefloquine | HE_HCoV-OC43 | Hemagglutinin-esterase | -6.51 | N/A | N/A | N/A | N/A |
| Amodiaquine | HE_MHV | Hemagglutinin-esterase | -5.96 | N/A | N/A | N/A | N/A |
| Cyclosporine | HE_MHV | Hemagglutinin-esterase | -5.67 | N/A | N/A | N/A | N/A |
| Loperamide | HE_MHV | Hemagglutinin-esterase | -7.37 | N/A | N/A | N/A | N/A |
| Tilorone | HE_MHV | Hemagglutinin-esterase | -5.12 | N/A | N/A | N/A | N/A |
| Mefloquine | HE_MHV | Hemagglutinin-esterase | -6.98 | N/A | N/A | N/A | N/A |
| Amodiaquine | IN_HIV1 | Gag-Pol polyprotein | -5.64 | -5.61 | N/A | N/A | N/A |
| Cyclosporine | IN_HIV1 | Gag-Pol polyprotein | ? | ? | N/A | N/A | N/A |
| Loperamide | IN_HIV1 | Gag-Pol polyprotein | -6.43 | -6.54 | N/A | N/A | N/A |
| Tilorone | IN_HIV1 | Gag-Pol polyprotein | -5.30 | -5.63 | N/A | N/A | N/A |
| Mefloquine | IN_HIV1 | Gag-Pol polyprotein | -5.93 | -5.63 | N/A | N/A | N/A |
| Amodiaquine | MD_HKU4 | Replicase polyprotein 1ab | -8.65 | -8.33 | -8.15 | N/A | N/A |
| Cyclosporine | MD_HKU4 | Replicase polyprotein 1ab | -5.44 | -5.78 | -6.44 | N/A | N/A |
| Loperamide | MD_HKU4 | Replicase polyprotein 1ab | -9.59 | -9.27 | -10.25 | N/A | N/A |
| Tilorone | MD_HKU4 | Replicase polyprotein 1ab | -7.70 | -7.66 | -7.63 | N/A | N/A |
| Mefloquine | MD_HKU4 | Replicase polyprotein 1ab | -8.16 | -7.40 | -8.00 | N/A | N/A |
| Amodiaquine | MD_MERs | Replicase polyprotein 1a | -8.42 | -8.44 | N/A | N/A | N/A |
| Cyclosporine | MD_MERs | Replicase polyprotein 1a | -6.15 | -6.72 | N/A | N/A | N/A |
| Loperamide | MD_MERs | Replicase polyprotein 1a | -10.90 | -10.04 | N/A | N/A | N/A |
| Tilorone | MD_MERs | Replicase polyprotein 1a | -7.72 | -7.38 | N/A | N/A | N/A |
| Mefloquine | MD_MERs | Replicase polyprotein 1a | -8.22 | -7.72 | N/A | N/A | N/A |
| Amodiaquine | MX2_A-H5N1 | Matrix protein 2 | -7.77 | N/A | N/A | N/A | N/A |
| Cyclosporine | MX2_A-H5N1 | Matrix protein 2 | ? | N/A | N/A | N/A | N/A |
| Loperamide | MX2_A-H5N1 | Matrix protein 2 | -0.31 | N/A | N/A | N/A | N/A |
| Tilorone | MX2_A-H5N1 | Matrix protein 2 | -6.45 | N/A | N/A | N/A | N/A |
| Mefloquine | MX2_A-H5N1 | Matrix protein 2 | -10.21 | N/A | N/A | N/A | N/A |
| Amodiaquine | NA_A-H11N6 | Neuraminidase | -7.15 | -7.04 | -6.66 | N/A | N/A |
| Cyclosporine | NA_A-H11N6 | Neuraminidase | ? | ? | ? | N/A | N/A |
| Loperamide | NA_A-H11N6 | Neuraminidase | -7.47 | -8.72 | -8.23 | N/A | N/A |
| Tilorone | NA_A-H11N6 | Neuraminidase | -6.40 | -6.41 | -6.36 | N/A | N/A |
| Mefloquine | NA_A-H11N6 | Neuraminidase | -8.11 | -8.31 | -8.54 | N/A | N/A |
| Amodiaquine | NA_A-H11N9 | Neuraminidase | -6.21 | -7.02 | -6.67 | N/A | N/A |
| Cyclosporine | NA_A-H11N9 | Neuraminidase | -6.16 | ? | ? | N/A | N/A |
| Loperamide | NA_A-H11N9 | Neuraminidase | -6.37 | -8.35 | -8.61 | N/A | N/A |
| Tilorone | NA_A-H11N9 | Neuraminidase | -5.16 | -6.71 | -6.57 | N/A | N/A |
| Mefloquine | NA_A-H11N9 | Neuraminidase | -5.93 | -8.09 | -8.66 | N/A | N/A |
| Amodiaquine | NA_A-H12N5 | Neuraminidase | -7.20 | -7.45 | -7.29 | N/A | N/A |
| Cyclosporine | NA_A-H12N5 | Neuraminidase | ? | ? | ? | N/A | N/A |
| Loperamide | NA_A-H12N5 | Neuraminidase | -8.12 | -7.43 | -7.31 | N/A | N/A |
| Tilorone | NA_A-H12N5 | Neuraminidase | -5.99 | -6.89 | -6.56 | N/A | N/A |
| Mefloquine | NA_A-H12N5 | Neuraminidase | -7.35 | -7.93 | -7.96 | N/A | N/A |
| Amodiaquine | NA_A-H13N9 | Neuraminidase | -5.74 | N/A | N/A | N/A | N/A |
| Cyclosporine | NA_A-H13N9 | Neuraminidase | -6.56 | N/A | N/A | N/A | N/A |
| Loperamide | NA_A-H13N9 | Neuraminidase | -7.05 | N/A | N/A | N/A | N/A |
| Tilorone | NA_A-H13N9 | Neuraminidase | -5.18 | N/A | N/A | N/A | N/A |
| Mefloquine | NA_A-H13N9 | Neuraminidase | -8.01 | N/A | N/A | N/A | N/A |
| Amodiaquine | NA_A-H17N10 | Neuraminidase | -7.03 | N/A | N/A | N/A | N/A |
| Cyclosporine | NA_A-H17N10 | Neuraminidase | ? | N/A | N/A | N/A | N/A |
| Loperamide | NA_A-H17N10 | Neuraminidase | -7.75 | N/A | N/A | N/A | N/A |
| Tilorone | NA_A-H17N10 | Neuraminidase | -6.21 | N/A | N/A | N/A | N/A |
| Mefloquine | NA_A-H17N10 | Neuraminidase | -7.32 | N/A | N/A | N/A | N/A |
| Amodiaquine | NA_A-H18N11 | Neuraminidase | -6.20 | N/A | N/A | N/A | N/A |
| Cyclosporine | NA_A-H18N11 | Neuraminidase | ? | N/A | N/A | N/A | N/A |
| Loperamide | NA_A-H18N11 | Neuraminidase | -7.06 | N/A | N/A | N/A | N/A |
| Tilorone | NA_A-H18N11 | Neuraminidase | -5.56 | N/A | N/A | N/A | N/A |
| Mefloquine | NA_A-H18N11 | Neuraminidase | -7.45 | N/A | N/A | N/A | N/A |
| Amodiaquine | NA_A-H1N1 | Neuraminidase | -6.82 | N/A | N/A | N/A | N/A |
| Cyclosporine | NA_A-H1N1 | Neuraminidase | 21.05 | N/A | N/A | N/A | N/A |
| Loperamide | NA_A-H1N1 | Neuraminidase | -7.87 | N/A | N/A | N/A | N/A |
| Tilorone | NA_A-H1N1 | Neuraminidase | -6.50 | N/A | N/A | N/A | N/A |
| Mefloquine | NA_A-H1N1 | Neuraminidase | -8.44 | N/A | N/A | N/A | N/A |
| Amodiaquine | NA_A-H2N2 | Neuraminidase | -7.45 | -6.68 | -6.80 | N/A | N/A |
| Cyclosporine | NA_A-H2N2 | Neuraminidase | ? | ? | ? | N/A | N/A |
| Loperamide | NA_A-H2N2 | Neuraminidase | -8.40 | -7.91 | -7.54 | N/A | N/A |
| Tilorone | NA_A-H2N2 | Neuraminidase | -6.04 | -6.71 | -6.39 | N/A | N/A |
| Mefloquine | NA_A-H2N2 | Neuraminidase | -8.07 | -8.58 | -7.34 | N/A | N/A |
| Amodiaquine | NA_A-H3N2 | Ig heavy chain Mem5 | -6.40 | -6.26 | N/A | N/A | N/A |
| Cyclosporine | NA_A-H3N2 | Ig heavy chain Mem5 | -7.21 | -6.42 | N/A | N/A | N/A |
| Loperamide | NA_A-H3N2 | Ig heavy chain Mem5 | -7.29 | -7.38 | N/A | N/A | N/A |
| Tilorone | NA_A-H3N2 | Ig heavy chain Mem5 | -5.88 | -5.30 | N/A | N/A | N/A |
| Mefloquine | NA_A-H3N2 | Ig heavy chain Mem5 | -8.24 | -7.38 | N/A | N/A | N/A |
| Amodiaquine | NA_A-H3N8 | Neuraminidase | -6.50 | -7.18 | -7.33 | N/A | N/A |
| Cyclosporine | NA_A-H3N8 | Neuraminidase | ? | ? | ? | N/A | N/A |
| Loperamide | NA_A-H3N8 | Neuraminidase | -8.26 | -8.44 | -7.43 | N/A | N/A |
| Tilorone | NA_A-H3N8 | Neuraminidase | -6.09 | -6.78 | -6.33 | N/A | N/A |
| Mefloquine | NA_A-H3N8 | Neuraminidase | -8.15 | -7.70 | -8.10 | N/A | N/A |
| Amodiaquine | NA_A-H5N1 | Neuraminidase | -7.30 | N/A | N/A | N/A | N/A |
| Cyclosporine | NA_A-H5N1 | Neuraminidase | ? | N/A | N/A | N/A | N/A |
| Loperamide | NA_A-H5N1 | Neuraminidase | -8.32 | N/A | N/A | N/A | N/A |
| Tilorone | NA_A-H5N1 | Neuraminidase | -6.77 | N/A | N/A | N/A | N/A |
| Mefloquine | NA_A-H5N1 | Neuraminidase | -8.39 | N/A | N/A | N/A | N/A |
| Amodiaquine | NA_A-H7N9 | Neuraminidase | -6.55 | -6.79 | -6.70 | N/A | N/A |
| Cyclosporine | NA_A-H7N9 | Neuraminidase | ? | ? | ? | N/A | N/A |
| Loperamide | NA_A-H7N9 | Neuraminidase | -8.35 | -7.12 | -7.94 | N/A | N/A |
| Tilorone | NA_A-H7N9 | Neuraminidase | -6.41 | -6.47 | -6.63 | N/A | N/A |
| Mefloquine | NA_A-H7N9 | Neuraminidase | -8.61 | -8.23 | -8.27 | N/A | N/A |
| Amodiaquine | NA_INFB | Neuraminidase | -6.74 | -6.78 | N/A | 23.24% | CHEMBL4161935 |
| Cyclosporine | NA_INFB | Neuraminidase | ? | ? | N/A | ? | ? |
| Loperamide | NA_INFB | Neuraminidase | -7.44 | -7.21 | N/A | 31.58% | CHEMBL113191 |
| Tilorone | NA_INFB | Neuraminidase | -6.46 | -6.23 | N/A | 23.53% | CHEMBL79499 |
| Mefloquine | NA_INFB | Neuraminidase | -7.86 | -7.95 | N/A | 31.67% | CHEMBL362993 |
| Amodiaquine | NP_A-H1N1 | Nucleoprotein | -6.14 | -6.44 | -6.31 | N/A | N/A |
| Cyclosporine | NP_A-H1N1 | Nucleoprotein | -2.81 | ? | ? | N/A | N/A |
| Loperamide | NP_A-H1N1 | Nucleoprotein | -6.98 | -6.61 | -6.82 | N/A | N/A |
| Tilorone | NP_A-H1N1 | Nucleoprotein | -5.19 | -6.86 | -5.33 | N/A | N/A |
| Mefloquine | NP_A-H1N1 | Nucleoprotein | -8.12 | -6.59 | -6.54 | N/A | N/A |
| Amodiaquine | NP_A-H5N1 | Nucleoprotein | -6.61 | N/A | N/A | N/A | N/A |
| Cyclosporine | NP_A-H5N1 | Nucleoprotein | -5.64 | N/A | N/A | N/A | N/A |
| Loperamide | NP_A-H5N1 | Nucleoprotein | -6.74 | N/A | N/A | N/A | N/A |
| Tilorone | NP_A-H5N1 | Nucleoprotein | -5.59 | N/A | N/A | N/A | N/A |
| Mefloquine | NP_A-H5N1 | Nucleoprotein | -7.09 | N/A | N/A | N/A | N/A |
| Amodiaquine | NP_HCoV-NL63 | Nucleoprotein | -6.39 | N/A | N/A | N/A | N/A |
| Cyclosporine | NP_HCoV-NL63 | Nucleoprotein | ? | N/A | N/A | N/A | N/A |
| Loperamide | NP_HCoV-NL63 | Nucleoprotein | -6.91 | N/A | N/A | N/A | N/A |
| Tilorone | NP_HCoV-NL63 | Nucleoprotein | -5.81 | N/A | N/A | N/A | N/A |
| Mefloquine | NP_HCoV-NL63 | Nucleoprotein | -6.88 | N/A | N/A | N/A | N/A |
| Amodiaquine | NP_HCoV-OC43 | Nucleoprotein | -8.11 | -7.02 | -6.94 | 30.09% | CHEMBL3233481 |
| Cyclosporine | NP_HCoV-OC43 | Nucleoprotein | -6.15 | ? | ? | ? | ? |
| Loperamide | NP_HCoV-OC43 | Nucleoprotein | -8.46 | -8.50 | -7.87 | 15.08% | CHEMBL3233481 |
| Tilorone | NP_HCoV-OC43 | Nucleoprotein | -8.56 | -6.87 | -5.62 | 10.61% | CHEMBL3233481 |
| Mefloquine | NP_HCoV-OC43 | Nucleoprotein | -8.98 | -7.61 | -7.51 | 22.15% | CHEMBL3233481 |
| Amodiaquine | NP_INFB | Nucleoprotein | -5.11 | N/A | N/A | N/A | N/A |
| Cyclosporine | NP_INFB | Nucleoprotein | ? | N/A | N/A | N/A | N/A |
| Loperamide | NP_INFB | Nucleoprotein | -5.94 | N/A | N/A | N/A | N/A |
| Tilorone | NP_INFB | Nucleoprotein | -4.74 | N/A | N/A | N/A | N/A |
| Mefloquine | NP_INFB | Nucleoprotein | -6.07 | N/A | N/A | N/A | N/A |
| Amodiaquine | NP_INFD | NP | -5.13 | N/A | N/A | N/A | N/A |
| Cyclosporine | NP_INFD | NP | ? | N/A | N/A | N/A | N/A |
| Loperamide | NP_INFD | NP | -6.22 | N/A | N/A | N/A | N/A |
| Tilorone | NP_INFD | NP | -4.80 | N/A | N/A | N/A | N/A |
| Mefloquine | NP_INFD | NP | -5.40 | N/A | N/A | N/A | N/A |
| Amodiaquine | NP_SARS | Nucleoprotein | -7.12 | N/A | N/A | N/A | N/A |
| Cyclosporine | NP_SARS | Nucleoprotein | ? | N/A | N/A | N/A | N/A |
| Loperamide | NP_SARS | Nucleoprotein | -8.39 | N/A | N/A | N/A | N/A |
| Tilorone | NP_SARS | Nucleoprotein | -6.46 | N/A | N/A | N/A | N/A |
| Mefloquine | NP_SARS | Nucleoprotein | -7.70 | N/A | N/A | N/A | N/A |
| Amodiaquine | NS3_HCV1A | Genome polyprotein | -7.51 | -6.06 | -6.56 | 33.33% | CHEMBL4111820 |
| Cyclosporine | NS3_HCV1A | Genome polyprotein | -6.42 | -6.17 | -6.01 | 72.29% | CHEMBL296588 |
| Loperamide | NS3_HCV1A | Genome polyprotein | -7.32 | -6.33 | -7.27 | 43.07% | CHEMBL3981499 |
| Tilorone | NS3_HCV1A | Genome polyprotein | -7.26 | -5.02 | -6.87 | 42.86% | CHEMBL4115040 |
| Mefloquine | NS3_HCV1A | Genome polyprotein | -8.64 | -6.51 | -8.51 | 35.47% | CHEMBL3906691 |
| Amodiaquine | NS3_HCV1B | Genome polyprotein | -8.11 | -6.86 | -5.69 | 23.11% | CHEMBL1170408 |
| Cyclosporine | NS3_HCV1B | Genome polyprotein | -6.42 | -5.88 | -5.26 | 52.25% | CHEMBL3927196 |
| Loperamide | NS3_HCV1B | Genome polyprotein | -7.25 | -7.41 | -6.48 | 22.76% | CHEMBL3927196 |
| Tilorone | NS3_HCV1B | Genome polyprotein | -7.36 | -7.13 | -5.21 | 21.16% | CHEMBL1170408 |
| Mefloquine | NS3_HCV1B | Genome polyprotein | -8.61 | -7.99 | -6.34 | 29.12% | CHEMBL1170417 |
| Amodiaquine | NS3_HCV3A | Genome polyprotein | -6.79 | -6.99 | -7.07 | N/A | N/A |
| Cyclosporine | NS3_HCV3A | Genome polyprotein | -5.64 | -6.85 | -6.50 | N/A | N/A |
| Loperamide | NS3_HCV3A | Genome polyprotein | -6.77 | -6.58 | -7.14 | N/A | N/A |
| Tilorone | NS3_HCV3A | Genome polyprotein | -5.61 | -5.32 | -5.85 | N/A | N/A |
| Mefloquine | NS3_HCV3A | Genome polyprotein | -7.94 | -8.10 | -8.05 | N/A | N/A |
| Amodiaquine | NS5B_HCV1A | Genome polyprotein | -7.51 | -8.02 | -8.18 | 27.70% | CHEMBL363650 |
| Cyclosporine | NS5B_HCV1A | Genome polyprotein | -6.77 | -3.09 | -4.57 | 50.00% | CHEMBL320324 |
| Loperamide | NS5B_HCV1A | Genome polyprotein | -8.59 | -9.72 | -9.73 | 38.56% | CHEMBL68034 |
| Tilorone | NS5B_HCV1A | Genome polyprotein | -6.80 | -7.73 | -7.95 | 29.69% | CHEMBL175894 |
| Mefloquine | NS5B_HCV1A | Genome polyprotein | -8.34 | -8.76 | -8.96 | 42.65% | CHEMBL353549 |
| Amodiaquine | NS5B_HCV1B | Genome polyprotein | -7.89 | -7.77 | -7.41 | 32.32% | CHEMBL3645194 |
| Cyclosporine | NS5B_HCV1B | Genome polyprotein | -7.70 | -6.40 | 27.21 | 19.26% | CHEMBL3422106 |
| Loperamide | NS5B_HCV1B | Genome polyprotein | -8.23 | -8.96 | -9.02 | 27.83% | CHEMBL3645208 |
| Tilorone | NS5B_HCV1B | Genome polyprotein | -6.95 | -7.12 | -6.66 | 20.66% | CHEMBL3645182 |
| Mefloquine | NS5B_HCV1B | Genome polyprotein | -8.50 | -7.94 | -7.63 | 32.18% | CHEMBL3422107 |
| Amodiaquine | NS5B_HCV2A | Genome polyprotein | -8.70 | -8.67 | N/A | N/A | N/A |
| Cyclosporine | NS5B_HCV2A | Genome polyprotein | 47.81 | ? | N/A | N/A | N/A |
| Loperamide | NS5B_HCV2A | Genome polyprotein | -8.82 | -8.24 | N/A | N/A | N/A |
| Tilorone | NS5B_HCV2A | Genome polyprotein | -7.89 | -8.50 | N/A | N/A | N/A |
| Mefloquine | NS5B_HCV2A | Genome polyprotein | -9.40 | -9.77 | N/A | N/A | N/A |
| Amodiaquine | NSP15_SARS | Replicase polyprotein 1ab | -6.48 | N/A | N/A | 24.54% | CHEMBL3105073 |
| Cyclosporine | NSP15_SARS | Replicase polyprotein 1ab | ? | N/A | N/A | ? | ? |
| Loperamide | NSP15_SARS | Replicase polyprotein 1ab | -7.38 | N/A | N/A | 44.78% | CHEMBL2441741 |
| Tilorone | NSP15_SARS | Replicase polyprotein 1ab | -5.68 | N/A | N/A | 21.12% | CHEMBL2441741 |
| Mefloquine | NSP15_SARS | Replicase polyprotein 1ab | -6.66 | N/A | N/A | 29.78% | CHEMBL2441741 |
| Amodiaquine | NSP1_INFB | Non-structural protein 1 | -6.31 | -6.24 | N/A | N/A | N/A |
| Cyclosporine | NSP1_INFB | Non-structural protein 1 | -5.54 | -5.39 | N/A | N/A | N/A |
| Loperamide | NSP1_INFB | Non-structural protein 1 | -7.50 | -7.12 | N/A | N/A | N/A |
| Tilorone | NSP1_INFB | Non-structural protein 1 | -5.75 | -5.82 | N/A | N/A | N/A |
| Mefloquine | NSP1_INFB | Non-structural protein 1 | -6.81 | -6.43 | N/A | N/A | N/A |
| Amodiaquine | NSP1_SARS | Replicase polyprotein 1ab | -6.06 | N/A | N/A | 24.54% | CHEMBL3105073 |
| Cyclosporine | NSP1_SARS | Replicase polyprotein 1ab | ? | N/A | N/A | ? | ? |
| Loperamide | NSP1_SARS | Replicase polyprotein 1ab | -6.40 | N/A | N/A | 44.78% | CHEMBL2441741 |
| Tilorone | NSP1_SARS | Replicase polyprotein 1ab | -5.36 | N/A | N/A | 21.12% | CHEMBL2441741 |
| Mefloquine | NSP1_SARS | Replicase polyprotein 1ab | -5.99 | N/A | N/A | 29.78% | CHEMBL2441741 |
| Amodiaquine | NSP3_HCoV-229E | Replicase polyprotein 1a | -8.94 | N/A | N/A | N/A | N/A |
| Cyclosporine | NSP3_HCoV-229E | Replicase polyprotein 1a | -6.19 | N/A | N/A | N/A | N/A |
| Loperamide | NSP3_HCoV-229E | Replicase polyprotein 1a | -10.37 | N/A | N/A | N/A | N/A |
| Tilorone | NSP3_HCoV-229E | Replicase polyprotein 1a | -8.50 | N/A | N/A | N/A | N/A |
| Mefloquine | NSP3_HCoV-229E | Replicase polyprotein 1a | -9.32 | N/A | N/A | N/A | N/A |
| Amodiaquine | NSP3_IBV | Replicase polyprotein 1a | -8.33 | N/A | N/A | N/A | N/A |
| Cyclosporine | NSP3_IBV | Replicase polyprotein 1a | -6.26 | N/A | N/A | N/A | N/A |
| Loperamide | NSP3_IBV | Replicase polyprotein 1a | -7.22 | N/A | N/A | N/A | N/A |
| Tilorone | NSP3_IBV | Replicase polyprotein 1a | -7.75 | N/A | N/A | N/A | N/A |
| Mefloquine | NSP3_IBV | Replicase polyprotein 1a | -8.82 | N/A | N/A | N/A | N/A |
| Amodiaquine | NSP3_MHV | Replicase polyprotein 1ab | -6.69 | N/A | N/A | N/A | N/A |
| Cyclosporine | NSP3_MHV | Replicase polyprotein 1ab | ? | N/A | N/A | N/A | N/A |
| Loperamide | NSP3_MHV | Replicase polyprotein 1ab | -7.64 | N/A | N/A | N/A | N/A |
| Tilorone | NSP3_MHV | Replicase polyprotein 1ab | -6.05 | N/A | N/A | N/A | N/A |
| Mefloquine | NSP3_MHV | Replicase polyprotein 1ab | -7.29 | N/A | N/A | N/A | N/A |
| Amodiaquine | NSP9_HCoV-229E | Replicase polyprotein 1ab | -6.99 | -5.90 | N/A | N/A | N/A |
| Cyclosporine | NSP9_HCoV-229E | Replicase polyprotein 1ab | ? | ? | N/A | N/A | N/A |
| Loperamide | NSP9_HCoV-229E | Replicase polyprotein 1ab | -7.88 | -7.02 | N/A | N/A | N/A |
| Tilorone | NSP9_HCoV-229E | Replicase polyprotein 1ab | -5.81 | -5.00 | N/A | N/A | N/A |
| Mefloquine | NSP9_HCoV-229E | Replicase polyprotein 1ab | -7.52 | -6.99 | N/A | N/A | N/A |
| Amodiaquine | PA_A-H17N10 | Polymerase acidic protein | -7.11 | N/A | N/A | N/A | N/A |
| Cyclosporine | PA_A-H17N10 | Polymerase acidic protein | ? | N/A | N/A | N/A | N/A |
| Loperamide | PA_A-H17N10 | Polymerase acidic protein | -8.31 | N/A | N/A | N/A | N/A |
| Tilorone | PA_A-H17N10 | Polymerase acidic protein | -6.44 | N/A | N/A | N/A | N/A |
| Mefloquine | PA_A-H17N10 | Polymerase acidic protein | -7.44 | N/A | N/A | N/A | N/A |
| Amodiaquine | PA_A-H1N1 | Polymerase acidic protein | -7.69 | -7.93 | -7.40 | N/A | N/A |
| Cyclosporine | PA_A-H1N1 | Polymerase acidic protein | -5.33 | -4.55 | -6.04 | N/A | N/A |
| Loperamide | PA_A-H1N1 | Polymerase acidic protein | -9.23 | -8.53 | -8.55 | N/A | N/A |
| Tilorone | PA_A-H1N1 | Polymerase acidic protein | -6.88 | -6.67 | -6.49 | N/A | N/A |
| Mefloquine | PA_A-H1N1 | Polymerase acidic protein | -7.41 | -7.80 | -7.63 | N/A | N/A |
| Amodiaquine | PA_A-H5N1 | Polymerase acidic protein | -7.71 | -7.38 | -7.47 | N/A | N/A |
| Cyclosporine | PA_A-H5N1 | Polymerase acidic protein | ? | ? | ? | N/A | N/A |
| Loperamide | PA_A-H5N1 | Polymerase acidic protein | -8.99 | -8.65 | -8.86 | N/A | N/A |
| Tilorone | PA_A-H5N1 | Polymerase acidic protein | -7.40 | -6.97 | -6.94 | N/A | N/A |
| Mefloquine | PA_A-H5N1 | Polymerase acidic protein | -7.63 | -7.58 | -7.59 | N/A | N/A |
| Amodiaquine | PA_INFA | Polymerase acidic protein | -8.36 | -6.88 | -6.78 | 30.83% | CHEMBL463590 |
| Cyclosporine | PA_INFA | Polymerase acidic protein | 6.47 | 6.08 | 29.61 | 30.08% | CHEMBL2040554 |
| Loperamide | PA_INFA | Polymerase acidic protein | -8.87 | -7.91 | -8.82 | 46.96% | CHEMBL2040554 |
| Tilorone | PA_INFA | Polymerase acidic protein | -6.91 | -6.63 | -7.08 | 40.54% | CHEMBL3600947 |
| Mefloquine | PA_INFA | Polymerase acidic protein | -8.38 | -7.86 | -7.87 | 30.38% | CHEMBL2040554 |
| Amodiaquine | PA_INFB | Polymerase acidic protein | -7.46 | N/A | N/A | N/A | N/A |
| Cyclosporine | PA_INFB | Polymerase acidic protein | -5.46 | N/A | N/A | N/A | N/A |
| Loperamide | PA_INFB | Polymerase acidic protein | -8.11 | N/A | N/A | N/A | N/A |
| Tilorone | PA_INFB | Polymerase acidic protein | -6.11 | N/A | N/A | N/A | N/A |
| Mefloquine | PA_INFB | Polymerase acidic protein | -7.12 | N/A | N/A | N/A | N/A |
| Amodiaquine | PB2_A-H3N2 | Polymerase basic protein 2 | -7.59 | -7.60 | N/A | N/A | N/A |
| Cyclosporine | PB2_A-H3N2 | Polymerase basic protein 2 | -5.98 | ? | N/A | N/A | N/A |
| Loperamide | PB2_A-H3N2 | Polymerase basic protein 2 | -8.85 | -8.47 | N/A | N/A | N/A |
| Tilorone | PB2_A-H3N2 | Polymerase basic protein 2 | -7.00 | -6.94 | N/A | N/A | N/A |
| Mefloquine | PB2_A-H3N2 | Polymerase basic protein 2 | -8.59 | -9.01 | N/A | N/A | N/A |
| Amodiaquine | PB2_A-H5N1 | Polymerase basic protein 2 | -7.12 | -7.71 | -7.65 | N/A | N/A |
| Cyclosporine | PB2_A-H5N1 | Polymerase basic protein 2 | -5.35 | -5.65 | 13.20 | N/A | N/A |
| Loperamide | PB2_A-H5N1 | Polymerase basic protein 2 | -8.94 | -7.55 | -8.34 | N/A | N/A |
| Tilorone | PB2_A-H5N1 | Polymerase basic protein 2 | -6.68 | -7.16 | -7.01 | N/A | N/A |
| Mefloquine | PB2_A-H5N1 | Polymerase basic protein 2 | -8.26 | -8.73 | -8.54 | N/A | N/A |
| Amodiaquine | PB2_INFB | Polymerase basic protein 2 | -7.82 | N/A | N/A | N/A | N/A |
| Cyclosporine | PB2_INFB | Polymerase basic protein 2 | ? | N/A | N/A | N/A | N/A |
| Loperamide | PB2_INFB | Polymerase basic protein 2 | -9.07 | N/A | N/A | N/A | N/A |
| Tilorone | PB2_INFB | Polymerase basic protein 2 | -7.19 | N/A | N/A | N/A | N/A |
| Mefloquine | PB2_INFB | Polymerase basic protein 2 | -8.31 | N/A | N/A | N/A | N/A |
| Amodiaquine | PB3_A-H3N2 | Polymerase basic protein 2 | -7.60 | N/A | N/A | N/A | N/A |
| Cyclosporine | PB3_A-H3N2 | Polymerase basic protein 2 | ? | N/A | N/A | N/A | N/A |
| Loperamide | PB3_A-H3N2 | Polymerase basic protein 2 | -8.37 | N/A | N/A | N/A | N/A |
| Tilorone | PB3_A-H3N2 | Polymerase basic protein 2 | -6.65 | N/A | N/A | N/A | N/A |
| Mefloquine | PB3_A-H3N2 | Polymerase basic protein 2 | -8.96 | N/A | N/A | N/A | N/A |
| Amodiaquine | PB4_A-H3N2 | Polymerase basic protein 2 | -7.70 | N/A | N/A | N/A | N/A |
| Cyclosporine | PB4_A-H3N2 | Polymerase basic protein 2 | -6.16 | N/A | N/A | N/A | N/A |
| Loperamide | PB4_A-H3N2 | Polymerase basic protein 2 | -8.93 | N/A | N/A | N/A | N/A |
| Tilorone | PB4_A-H3N2 | Polymerase basic protein 2 | -7.11 | N/A | N/A | N/A | N/A |
| Mefloquine | PB4_A-H3N2 | Polymerase basic protein 2 | -8.91 | N/A | N/A | N/A | N/A |
| Amodiaquine | PLP_SARS | Replicase polyprotein 1a | -8.28 | -7.70 | -7.88 | 28.00% | CHEMBL358279 |
| Cyclosporine | PLP_SARS | Replicase polyprotein 1a | -6.40 | -5.93 | -6.02 | 41.79% | CHEMBL213054 |
| Loperamide | PLP_SARS | Replicase polyprotein 1a | -9.26 | -9.46 | -9.90 | 33.56% | CHEMBL213054 |
| Tilorone | PLP_SARS | Replicase polyprotein 1a | -7.44 | -7.85 | -7.66 | 29.20% | CHEMBL222735 |
| Mefloquine | PLP_SARS | Replicase polyprotein 1a | -9.13 | -8.37 | -9.66 | 26.82% | CHEMBL358279 |
| Amodiaquine | PR_FCoV | Replicase polyprotein 1ab | -6.61 | N/A | N/A | N/A | N/A |
| Cyclosporine | PR_FCoV | Replicase polyprotein 1ab | -5.43 | N/A | N/A | N/A | N/A |
| Loperamide | PR_FCoV | Replicase polyprotein 1ab | -7.59 | N/A | N/A | N/A | N/A |
| Tilorone | PR_FCoV | Replicase polyprotein 1ab | -5.89 | N/A | N/A | N/A | N/A |
| Mefloquine | PR_FCoV | Replicase polyprotein 1ab | -7.85 | N/A | N/A | N/A | N/A |
| Amodiaquine | PR_HCoV-229E | Replicase polyprotein 1a | -7.09 | -6.35 | N/A | N/A | N/A |
| Cyclosporine | PR_HCoV-229E | Replicase polyprotein 1a | -4.31 | -4.70 | N/A | N/A | N/A |
| Loperamide | PR_HCoV-229E | Replicase polyprotein 1a | -7.91 | -7.22 | N/A | N/A | N/A |
| Tilorone | PR_HCoV-229E | Replicase polyprotein 1a | -5.61 | -5.55 | N/A | N/A | N/A |
| Mefloquine | PR_HCoV-229E | Replicase polyprotein 1a | -7.46 | -7.30 | N/A | N/A | N/A |
| Amodiaquine | PR_HCoV-NL63 | Replicase polyprotein 1a | -4.35 | -6.93 | N/A | N/A | N/A |
| Cyclosporine | PR_HCoV-NL63 | Replicase polyprotein 1a | -3.95 | -5.58 | N/A | N/A | N/A |
| Loperamide | PR_HCoV-NL63 | Replicase polyprotein 1a | -4.61 | -8.07 | N/A | N/A | N/A |
| Tilorone | PR_HCoV-NL63 | Replicase polyprotein 1a | -4.17 | -5.82 | N/A | N/A | N/A |
| Mefloquine | PR_HCoV-NL63 | Replicase polyprotein 1a | -5.64 | -8.38 | N/A | N/A | N/A |
| Amodiaquine | PR_HIV1 | Gag-Pol polyprotein | -6.57 | -6.70 | -6.36 | 13.93% | CHEMBL510485 |
| Cyclosporine | PR_HIV1 | Gag-Pol polyprotein | 9.92 | -6.70 | -6.63 | 21.02% | CHEMBL492666 |
| Loperamide | PR_HIV1 | Gag-Pol polyprotein | -7.19 | -6.59 | -6.84 | 28.73% | CHEMBL3645129 |
| Tilorone | PR_HIV1 | Gag-Pol polyprotein | -5.48 | -6.06 | -5.68 | 26.49% | CHEMBL450294 |
| Mefloquine | PR_HIV1 | Gag-Pol polyprotein | -6.69 | -7.21 | -6.76 | 29.50% | CHEMBL492666 |
| Amodiaquine | PR_HIV2 | Gag-Pol polyprotein | -7.17 | -6.21 | N/A | N/A | N/A |
| Cyclosporine | PR_HIV2 | Gag-Pol polyprotein | -5.51 | -6.06 | N/A | N/A | N/A |
| Loperamide | PR_HIV2 | Gag-Pol polyprotein | -8.12 | -6.98 | N/A | N/A | N/A |
| Tilorone | PR_HIV2 | Gag-Pol polyprotein | -5.69 | -5.95 | N/A | N/A | N/A |
| Mefloquine | PR_HIV2 | Gag-Pol polyprotein | -7.17 | -6.88 | N/A | N/A | N/A |
| Amodiaquine | PR_HKU1 | Replicase polyprotein 1a | -6.49 | N/A | N/A | N/A | N/A |
| Cyclosporine | PR_HKU1 | Replicase polyprotein 1a | -5.09 | N/A | N/A | N/A | N/A |
| Loperamide | PR_HKU1 | Replicase polyprotein 1a | -6.96 | N/A | N/A | N/A | N/A |
| Tilorone | PR_HKU1 | Replicase polyprotein 1a | -5.68 | N/A | N/A | N/A | N/A |
| Mefloquine | PR_HKU1 | Replicase polyprotein 1a | -6.70 | N/A | N/A | N/A | N/A |
| Amodiaquine | PR_HKU4 | Replicase polyprotein 1ab | -6.95 | -7.19 | -7.21 | N/A | N/A |
| Cyclosporine | PR_HKU4 | Replicase polyprotein 1ab | -5.19 | -5.35 | -5.22 | N/A | N/A |
| Loperamide | PR_HKU4 | Replicase polyprotein 1ab | -7.83 | -7.55 | -7.98 | N/A | N/A |
| Tilorone | PR_HKU4 | Replicase polyprotein 1ab | -6.02 | -6.51 | -6.40 | N/A | N/A |
| Mefloquine | PR_HKU4 | Replicase polyprotein 1ab | -7.22 | -7.07 | -7.00 | N/A | N/A |
| Amodiaquine | PR_IBV | Replicase polyprotein 1a | -7.09 | N/A | N/A | N/A | N/A |
| Cyclosporine | PR_IBV | Replicase polyprotein 1a | -4.97 | N/A | N/A | N/A | N/A |
| Loperamide | PR_IBV | Replicase polyprotein 1a | -7.08 | N/A | N/A | N/A | N/A |
| Tilorone | PR_IBV | Replicase polyprotein 1a | -6.38 | N/A | N/A | N/A | N/A |
| Mefloquine | PR_IBV | Replicase polyprotein 1a | -7.61 | N/A | N/A | N/A | N/A |
| Amodiaquine | PR_MERs | 3C-like proteinase | -7.33 | -7.19 | N/A | N/A | N/A |
| Cyclosporine | PR_MERs | 3C-like proteinase | -4.46 | -5.11 | N/A | N/A | N/A |
| Loperamide | PR_MERs | 3C-like proteinase | -6.17 | -7.79 | N/A | N/A | N/A |
| Tilorone | PR_MERs | 3C-like proteinase | -6.06 | -6.37 | N/A | N/A | N/A |
| Mefloquine | PR_MERs | 3C-like proteinase | -7.98 | -7.63 | N/A | N/A | N/A |
| Amodiaquine | PR_PEDV | 3C-like proteinase | -6.85 | N/A | N/A | N/A | N/A |
| Cyclosporine | PR_PEDV | 3C-like proteinase | -3.72 | N/A | N/A | N/A | N/A |
| Loperamide | PR_PEDV | 3C-like proteinase | -7.89 | N/A | N/A | N/A | N/A |
| Tilorone | PR_PEDV | 3C-like proteinase | -5.93 | N/A | N/A | N/A | N/A |
| Mefloquine | PR_PEDV | 3C-like proteinase | -7.89 | N/A | N/A | N/A | N/A |
| Amodiaquine | PR_SARS | Replicase polyprotein 1ab | -7.14 | -6.91 | -7.06 | 24.54% | CHEMBL3105073 |
| Cyclosporine | PR_SARS | Replicase polyprotein 1ab | -6.18 | -6.33 | -4.95 | 35.04% | CHEMBL2441741 |
| Loperamide | PR_SARS | Replicase polyprotein 1ab | -6.71 | -7.20 | -6.89 | 44.78% | CHEMBL2441741 |
| Tilorone | PR_SARS | Replicase polyprotein 1ab | -6.32 | -6.19 | -6.11 | 21.12% | CHEMBL2441741 |
| Mefloquine | PR_SARS | Replicase polyprotein 1ab | -8.07 | -6.98 | -7.67 | 29.78% | CHEMBL2441741 |
| Amodiaquine | PR_SARS2 | 3C-like protease | -7.23 | N/A | N/A | N/A | N/A |
| Cyclosporine | PR_SARS2 | 3C-like protease | -5.54 | N/A | N/A | N/A | N/A |
| Loperamide | PR_SARS2 | 3C-like protease | -7.27 | N/A | N/A | N/A | N/A |
| Tilorone | PR_SARS2 | 3C-like protease | -6.12 | N/A | N/A | N/A | N/A |
| Mefloquine | PR_SARS2 | 3C-like protease | -7.63 | N/A | N/A | N/A | N/A |
| Amodiaquine | PR_TGEV | Replicase polyprotein 1a | -6.88 | N/A | N/A | N/A | N/A |
| Cyclosporine | PR_TGEV | Replicase polyprotein 1a | -6.27 | N/A | N/A | N/A | N/A |
| Loperamide | PR_TGEV | Replicase polyprotein 1a | -7.18 | N/A | N/A | N/A | N/A |
| Tilorone | PR_TGEV | Replicase polyprotein 1a | -5.97 | N/A | N/A | N/A | N/A |
| Mefloquine | PR_TGEV | Replicase polyprotein 1a | -6.47 | N/A | N/A | N/A | N/A |
| Amodiaquine | RT_HIV1 | Gag-Pol polyprotein | -9.06 | -9.09 | -9.04 | 33.79% | CHEMBL4291913 |
| Cyclosporine | RT_HIV1 | Gag-Pol polyprotein | ? | ? | ? | ? | ? |
| Loperamide | RT_HIV1 | Gag-Pol polyprotein | -8.48 | -9.45 | -9.05 | 41.67% | CHEMBL4226544 |
| Tilorone | RT_HIV1 | Gag-Pol polyprotein | -8.40 | -7.73 | -7.55 | 28.87% | CHEMBL4225614 |
| Mefloquine | RT_HIV1 | Gag-Pol polyprotein | -10.87 | -10.77 | -10.57 | 46.58% | CHEMBL4227326 |
| Amodiaquine | SPIKE_HCoV-229E | Spike glycoprotein | -4.92 | N/A | N/A | N/A | N/A |
| Cyclosporine | SPIKE_HCoV-229E | Spike glycoprotein | -5.50 | N/A | N/A | N/A | N/A |
| Loperamide | SPIKE_HCoV-229E | Spike glycoprotein | -5.91 | N/A | N/A | N/A | N/A |
| Tilorone | SPIKE_HCoV-229E | Spike glycoprotein | -4.49 | N/A | N/A | N/A | N/A |
| Mefloquine | SPIKE_HCoV-229E | Spike glycoprotein | -5.64 | N/A | N/A | N/A | N/A |
| Amodiaquine | SPIKE_HCoV-NL63 | Spike glycoprotein | -5.80 | N/A | N/A | N/A | N/A |
| Cyclosporine | SPIKE_HCoV-NL63 | Spike glycoprotein | -5.85 | N/A | N/A | N/A | N/A |
| Loperamide | SPIKE_HCoV-NL63 | Spike glycoprotein | -6.42 | N/A | N/A | N/A | N/A |
| Tilorone | SPIKE_HCoV-NL63 | Spike glycoprotein | -5.42 | N/A | N/A | N/A | N/A |
| Mefloquine | SPIKE_HCoV-NL63 | Spike glycoprotein | -6.34 | N/A | N/A | N/A | N/A |
| Amodiaquine | SPIKE_HCoV-OC43 | Spike glycoprotein | -6.34 | N/A | N/A | N/A | N/A |
| Cyclosporine | SPIKE_HCoV-OC43 | Spike glycoprotein | 81.63 | N/A | N/A | N/A | N/A |
| Loperamide | SPIKE_HCoV-OC43 | Spike glycoprotein | -6.80 | N/A | N/A | N/A | N/A |
| Tilorone | SPIKE_HCoV-OC43 | Spike glycoprotein | -5.79 | N/A | N/A | N/A | N/A |
| Mefloquine | SPIKE_HCoV-OC43 | Spike glycoprotein | -6.86 | N/A | N/A | N/A | N/A |
| Amodiaquine | SPIKE_HKU4 | Spike glycoprotein | -6.47 | N/A | N/A | N/A | N/A |
| Cyclosporine | SPIKE_HKU4 | Spike glycoprotein | -6.59 | N/A | N/A | N/A | N/A |
| Loperamide | SPIKE_HKU4 | Spike glycoprotein | -7.65 | N/A | N/A | N/A | N/A |
| Tilorone | SPIKE_HKU4 | Spike glycoprotein | -6.35 | N/A | N/A | N/A | N/A |
| Mefloquine | SPIKE_HKU4 | Spike glycoprotein | -7.61 | N/A | N/A | N/A | N/A |
| Amodiaquine | SPIKE_IBV | Spike glycoprotein | -5.75 | N/A | N/A | N/A | N/A |
| Cyclosporine | SPIKE_IBV | Spike glycoprotein | ? | N/A | N/A | N/A | N/A |
| Loperamide | SPIKE_IBV | Spike glycoprotein | -6.09 | N/A | N/A | N/A | N/A |
| Tilorone | SPIKE_IBV | Spike glycoprotein | -5.45 | N/A | N/A | N/A | N/A |
| Mefloquine | SPIKE_IBV | Spike glycoprotein | -6.32 | N/A | N/A | N/A | N/A |
| Amodiaquine | SPIKE_MERs | Spike glycoprotein | -6.29 | -5.87 | -5.33 | N/A | N/A |
| Cyclosporine | SPIKE_MERs | Spike glycoprotein | -6.91 | -6.59 | -6.71 | N/A | N/A |
| Loperamide | SPIKE_MERs | Spike glycoprotein | -7.00 | -6.14 | -5.94 | N/A | N/A |
| Tilorone | SPIKE_MERs | Spike glycoprotein | -5.91 | -6.09 | -5.16 | N/A | N/A |
| Mefloquine | SPIKE_MERs | Spike glycoprotein | -6.75 | -6.97 | -6.22 | N/A | N/A |
| Amodiaquine | SPIKE_MHV | Spike glycoprotein | -6.83 | N/A | N/A | N/A | N/A |
| Cyclosporine | SPIKE_MHV | Spike glycoprotein | -5.68 | N/A | N/A | N/A | N/A |
| Loperamide | SPIKE_MHV | Spike glycoprotein | -7.56 | N/A | N/A | N/A | N/A |
| Tilorone | SPIKE_MHV | Spike glycoprotein | -5.56 | N/A | N/A | N/A | N/A |
| Mefloquine | SPIKE_MHV | Spike glycoprotein | -7.71 | N/A | N/A | N/A | N/A |
| Amodiaquine | SPIKE_PDCoV | Spike protein | -5.91 | N/A | N/A | N/A | N/A |
| Cyclosporine | SPIKE_PDCoV | Spike protein | ? | N/A | N/A | N/A | N/A |
| Loperamide | SPIKE_PDCoV | Spike protein | -6.11 | N/A | N/A | N/A | N/A |
| Tilorone | SPIKE_PDCoV | Spike protein | -4.94 | N/A | N/A | N/A | N/A |
| Mefloquine | SPIKE_PDCoV | Spike protein | -6.83 | N/A | N/A | N/A | N/A |
| Amodiaquine | SPIKE_SARS | Spike glycoprotein | -6.09 | -6.53 | N/A | N/A | N/A |
| Cyclosporine | SPIKE_SARS | Spike glycoprotein | -6.20 | -6.78 | N/A | N/A | N/A |
| Loperamide | SPIKE_SARS | Spike glycoprotein | -6.33 | -7.03 | N/A | N/A | N/A |
| Tilorone | SPIKE_SARS | Spike glycoprotein | -5.72 | -5.80 | N/A | N/A | N/A |
| Mefloquine | SPIKE_SARS | Spike glycoprotein | -6.55 | -7.59 | N/A | N/A | N/A |
| Amodiaquine | SPIKE_SARS2 | Spike glycoprotein | -5.47 | N/A | N/A | N/A | N/A |
| Cyclosporine | SPIKE_SARS2 | Spike glycoprotein | -6.65 | N/A | N/A | N/A | N/A |
| Loperamide | SPIKE_SARS2 | Spike glycoprotein | -7.00 | N/A | N/A | N/A | N/A |
| Tilorone | SPIKE_SARS2 | Spike glycoprotein | -4.89 | N/A | N/A | N/A | N/A |
| Mefloquine | SPIKE_SARS2 | Spike glycoprotein | -6.57 | N/A | N/A | N/A | N/A |