| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -5.88 | -5.84 | -5.47 | 35.38% | CHEMBL1255086 | Inactive | 74.68% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -6.04 | -6.32 | -5.90 | 33.90% | CHEMBL2112766 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -5.96 | -5.93 | -6.10 | 29.69% | CHEMBL140416 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -6.21 | -6.34 | -5.64 | 24.68% | CHEMBL39 | Inactive | 56.81% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -5.70 | -5.54 | -6.13 | 24.68% | CHEMBL39 | Inactive | 81.81% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -6.16 | -5.63 | N/A | 34.85% | CHEMBL272942 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -6.22 | -5.85 | -6.27 | 37.04% | CHEMBL558 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -5.69 | -6.37 | N/A | 34.85% | CHEMBL272942 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -6.21 | -6.14 | -5.86 | 37.50% | CHEMBL1258451 | Inactive | 61.00% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -5.85 | -5.88 | -5.69 | 27.38% | CHEMBL365084 | Active | 52.39% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -5.94 | -5.61 | -5.92 | 30.38% | CHEMBL41 | Inactive | 82.98% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -5.54 | -6.02 | -5.60 | 31.33% | CHEMBL3262419 | Inactive | 51.89% |
| AA1R_HUMAN | adenosine A1 receptor | -5.62 | -5.54 | -5.85 | 35.82% | CHEMBL1487093 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -5.35 | -5.94 | -5.75 | 35.82% | CHEMBL1487093 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -6.05 | -6.78 | -5.93 | 35.82% | CHEMBL1487093 | Active | 51.30% |
| AA3R_HUMAN | adenosine A3 receptor | -5.84 | -5.85 | -5.66 | 35.82% | CHEMBL1487093 | Active | 61.10% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -6.03 | -6.33 | N/A | 39.68% | CHEMBL4102555 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -5.83 | -5.59 | -5.91 | 35.00% | CHEMBL1290634 | Active | 62.48% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -5.60 | -6.20 | -6.39 | 39.68% | CHEMBL4102555 | Inactive | 61.81% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -5.88 | -5.86 | N/A | 33.85% | CHEMBL55 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -6.09 | -5.81 | -6.14 | 30.38% | CHEMBL41 | Inactive | 80.34% |
| ACTHR_HUMAN | melanocortin 2 receptor | -7.19 | -6.71 | -5.67 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -5.35 | -5.17 | -5.17 | 38.98% | CHEMBL679 | Active | 53.27% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -6.22 | -6.24 | -6.45 | 42.59% | CHEMBL1437 | Active | 78.23% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -6.63 | -6.53 | -6.48 | 42.59% | CHEMBL1437 | Active | 65.70% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -5.87 | -6.06 | -6.14 | 42.59% | CHEMBL1437 | Active | 68.41% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -6.09 | -6.13 | -5.96 | 40.24% | CHEMBL520903 | Active | 52.80% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -6.20 | -6.38 | -6.39 | 44.78% | CHEMBL1902287 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -6.40 | -6.64 | -6.31 | 42.59% | CHEMBL1437 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -5.32 | -5.74 | -5.60 | 23.30% | CHEMBL376286 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -5.92 | -6.25 | -5.81 | 26.39% | CHEMBL121565 | Inactive | 87.58% |
| CALCR_HUMAN | calcitonin receptor | -5.48 | -5.17 | -5.84 | 15.85% | CHEMBL4565938 | Active | 77.43% |
| CCKAR_HUMAN | cholecystokinin A receptor | -5.20 | -5.56 | -6.56 | 24.26% | CHEMBL1784685 | Inactive | 96.14% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -5.53 | -6.60 | -5.29 | 34.38% | CHEMBL3138187 | Inactive | 98.35% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -5.64 | -5.39 | -5.17 | 35.11% | CHEMBL1171788 | Inactive | 92.74% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -5.70 | -5.89 | -5.93 | 30.38% | CHEMBL1618631 | Inactive | 77.36% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -6.51 | -5.20 | -6.72 | 29.55% | CHEMBL319689 | Inactive | 99.54% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -5.92 | -6.37 | -6.38 | 35.71% | CHEMBL127842 | Inactive | 97.18% |
| CNR1_HUMAN | cannabinoid receptor 1 | -5.43 | -5.59 | -6.01 | 46.43% | CHEMBL243334 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -5.72 | -6.10 | N/A | 46.43% | CHEMBL243334 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.50 | N/A | N/A | 23.62% | CHEMBL464302 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -6.38 | -5.50 | -4.88 | 28.70% | CHEMBL380052 | Inactive | 63.10% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -5.87 | -5.88 | -5.85 | 26.04% | CHEMBL1085258 | Inactive | 97.34% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -6.35 | -5.44 | -5.56 | 27.91% | CHEMBL126657 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -5.88 | -5.68 | -6.20 | 83.33% | CHEMBL441343 | Active | 88.55% |
| DRD2_HUMAN | dopamine receptor D2 | -5.22 | N/A | N/A | 42.59% | CHEMBL1437 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -5.94 | N/A | N/A | 46.55% | CHEMBL286494 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -6.12 | -6.11 | N/A | 37.93% | CHEMBL59326 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -6.99 | -7.05 | -6.09 | 35.29% | CHEMBL59 | Inactive | 91.73% |
| EDNRA_HUMAN | endothelin receptor type A | -4.91 | -5.28 | -6.70 | 29.33% | CHEMBL290026 | Inactive | 86.89% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -5.79 | -5.91 | -7.77 | 13.56% | CHEMBL2391908 | Inactive | 90.44% |
| GASR_HUMAN | cholecystokinin B receptor | -5.67 | -5.28 | -5.25 | 22.83% | CHEMBL38874 | Inactive | 94.04% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -6.36 | -6.46 | -6.33 | 26.80% | CHEMBL441844 | Inactive | 88.26% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -6.69 | -6.82 | -6.62 | 33.33% | CHEMBL3892611 | Inactive | 72.64% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -7.07 | -7.09 | -6.84 | 32.05% | CHEMBL2112634 | Inactive | 66.40% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -5.53 | -4.99 | -5.10 | 25.77% | CHEMBL561835 | Inactive | 95.54% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -6.52 | -6.57 | -6.53 | 38.27% | CHEMBL1348198 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -6.01 | -6.03 | -6.14 | 19.01% | CHEMBL566136 | Inactive | 93.86% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.12 | -5.92 | -6.32 | 23.71% | CHEMBL432038 | Inactive | 99.81% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -5.87 | -5.96 | -5.77 | 34.25% | CHEMBL143210 | Inactive | 98.35% |
| HRH1_HUMAN | histamine receptor H1 | -7.05 | N/A | N/A | 36.62% | CHEMBL570033 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -7.43 | -5.65 | -6.39 | 28.00% | CHEMBL490632 | Active | 77.68% |
| HRH3_HUMAN | histamine receptor H3 | -5.72 | -5.41 | -5.44 | 41.43% | CHEMBL544242 | Active | 86.42% |
| HRH4_HUMAN | histamine receptor H4 | -5.87 | -5.81 | -5.74 | 29.85% | CHEMBL4072893 | Active | 50.57% |
| MC3R_HUMAN | melanocortin 3 receptor | -5.91 | -5.48 | -6.05 | 20.00% | CHEMBL392092 | Inactive | 82.33% |
| MC4R_HUMAN | melanocortin 4 receptor | -4.88 | -4.71 | -4.78 | 25.74% | CHEMBL1380969 | Inactive | 94.43% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.69 | -5.77 | -5.39 | 23.36% | CHEMBL3907645 | Inactive | 69.78% |
| MSHR_HUMAN | melanocortin 1 receptor | -5.74 | -5.15 | -6.89 | 19.81% | CHEMBL379054 | Inactive | 57.84% |
| NK1R_HUMAN | tachykinin receptor 1 | -5.76 | -5.43 | -5.37 | 29.87% | CHEMBL93909 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -5.32 | -5.09 | -5.47 | 42.65% | CHEMBL4111499 | Inactive | 99.13% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -5.27 | -5.60 | -5.75 | 20.44% | CHEMBL1706758 | Inactive | 92.07% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -5.52 | -5.25 | -5.37 | 21.85% | CHEMBL3361432 | Inactive | 61.23% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -5.46 | -6.29 | -5.86 | 20.20% | CHEMBL3086828 | Inactive | 82.72% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -6.01 | -6.30 | -5.70 | 31.25% | CHEMBL3559801 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -5.85 | -5.16 | -5.18 | 31.25% | CHEMBL3559801 | Active | 50.35% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -5.64 | -5.41 | -5.17 | 31.25% | CHEMBL3559801 | Active | 94.73% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -5.77 | -6.54 | -5.85 | 31.25% | CHEMBL3559801 | Inactive | 91.24% |
| OPRD_HUMAN | opioid receptor delta 1 | -5.70 | -4.46 | -5.07 | 39.39% | CHEMBL340699 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -5.66 | -5.78 | -6.11 | 33.33% | CHEMBL1188090 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -6.22 | -5.52 | -5.52 | 33.77% | CHEMBL423726 | Inactive | 93.05% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -5.46 | -5.31 | -5.42 | 28.74% | CHEMBL233493 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -5.79 | -6.17 | -6.15 | 27.06% | CHEMBL297624 | Inactive | 85.57% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -5.95 | -5.84 | -5.47 | 46.34% | CHEMBL406341 | Active | 82.65% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -5.98 | -6.19 | -6.05 | 24.22% | CHEMBL1331194 | Inactive | 91.14% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -5.90 | -5.76 | -6.43 | 27.43% | CHEMBL3416859 | Inactive | 96.79% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -5.73 | -5.88 | -5.75 | 24.26% | CHEMBL1784685 | N/A | N/A |