| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.12 | -6.56 | -8.01 | 56.83% | CHEMBL163884 | Inactive | 54.77% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.09 | -8.96 | -7.75 | 56.12% | CHEMBL111107 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.15 | -6.98 | -8.14 | 49.73% | CHEMBL267615 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -7.24 | -8.12 | -7.60 | 49.73% | CHEMBL267615 | Active | 60.98% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.24 | -9.59 | -9.26 | 38.81% | CHEMBL263700 | Inactive | 56.59% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.74 | -7.93 | N/A | 49.73% | CHEMBL267615 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.59 | -8.88 | -9.03 | 76.88% | CHEMBL15245 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.85 | -8.33 | N/A | 53.14% | CHEMBL553794 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -8.59 | -8.43 | -7.76 | 47.69% | CHEMBL3901228 | Inactive | 54.98% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -7.09 | -6.91 | -7.16 | 54.77% | CHEMBL126823 | Active | 67.36% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -7.46 | -7.18 | -7.85 | 76.88% | CHEMBL15245 | Active | 98.37% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.10 | -8.85 | -8.76 | 65.73% | CHEMBL308461 | Active | 94.04% |
| AA1R_HUMAN | adenosine A1 receptor | -8.06 | -8.96 | -5.52 | 41.31% | CHEMBL411329 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -7.80 | -7.73 | -7.29 | 51.04% | CHEMBL3929822 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.94 | -9.45 | -8.05 | 39.39% | CHEMBL3317576 | Inactive | 62.35% |
| AA3R_HUMAN | adenosine A3 receptor | -4.82 | -2.33 | -4.83 | 76.88% | CHEMBL15245 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -6.45 | 7.35 | N/A | 47.31% | CHEMBL318995 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -8.76 | -8.07 | -5.44 | 52.65% | CHEMBL326450 | Active | 67.22% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.73 | -8.83 | -7.80 | 54.29% | CHEMBL105160 | Active | 74.09% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -6.11 | -5.18 | N/A | 54.29% | CHEMBL105160 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -5.85 | -6.90 | -8.15 | 46.88% | CHEMBL106219 | Active | 72.90% |
| ACTHR_HUMAN | melanocortin 2 receptor | -8.11 | -8.28 | -8.13 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.27 | -7.70 | -8.58 | 76.88% | CHEMBL15245 | Active | 94.27% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | 2.19 | 1.16 | 3.47 | 80.50% | CHEMBL122404 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -8.20 | -8.69 | -6.84 | 80.50% | CHEMBL122404 | Active | 95.44% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 0.51 | 1.86 | 1.98 | 80.50% | CHEMBL122404 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.33 | -7.49 | -7.98 | 44.14% | CHEMBL463182 | Inactive | 58.96% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -7.01 | -7.83 | -9.31 | 45.75% | CHEMBL236042 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -8.96 | -9.14 | -8.94 | 45.67% | CHEMBL462780 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -7.83 | -8.08 | -7.63 | 43.59% | CHEMBL154057 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -7.52 | -8.06 | -7.58 | 44.18% | CHEMBL559565 | Inactive | 69.00% |
| CALCR_HUMAN | calcitonin receptor | -7.28 | -8.38 | -8.29 | 33.71% | CHEMBL2369897 | Inactive | 98.04% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.03 | -7.76 | -8.22 | 50.39% | CHEMBL2372623 | Inactive | 89.84% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.16 | -8.49 | -7.21 | 49.77% | CHEMBL308209 | Inactive | 92.99% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -7.98 | -7.76 | -7.07 | 44.75% | CHEMBL3263271 | Inactive | 76.06% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.85 | -7.47 | -7.52 | 40.94% | CHEMBL2435852 | Inactive | 63.81% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.03 | -7.45 | -7.58 | 46.02% | CHEMBL1628706 | Inactive | 95.94% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -7.87 | -8.03 | -9.40 | 45.11% | CHEMBL3597626 | Active | 58.06% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.13 | -7.40 | -9.05 | 57.20% | CHEMBL445022 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -9.12 | -9.73 | N/A | 52.78% | CHEMBL2029729 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | 0.28 | N/A | N/A | 32.45% | CHEMBL556862 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -7.80 | -7.64 | -7.23 | 40.83% | CHEMBL404088 | Inactive | 50.81% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.22 | -8.17 | -8.44 | 43.87% | CHEMBL496564 | Inactive | 89.23% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.73 | -7.27 | -8.43 | 56.59% | CHEMBL1644072 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -8.08 | -8.31 | -8.80 | 54.55% | CHEMBL287513 | Active | 77.97% |
| DRD2_HUMAN | dopamine receptor D2 | -7.31 | N/A | N/A | 76.88% | CHEMBL15245 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -7.75 | N/A | N/A | 52.86% | CHEMBL136711 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -7.69 | -8.92 | N/A | 45.75% | CHEMBL310867 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -6.24 | -6.55 | -8.20 | 50.26% | CHEMBL201584 | Active | 67.11% |
| EDNRA_HUMAN | endothelin receptor type A | -7.05 | -7.88 | -7.92 | 47.66% | CHEMBL320631 | Inactive | 51.52% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 5.90 | 6.08 | 10.52 | 22.41% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.02 | -7.06 | -6.94 | 50.63% | CHEMBL293026 | Inactive | 65.45% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.65 | -7.57 | -5.40 | 44.67% | CHEMBL178741 | Inactive | 53.45% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | 2.25 | 3.68 | 5.23 | 42.80% | CHEMBL3901998 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | 2.90 | -0.76 | -2.97 | 34.51% | CHEMBL3885379 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 5.93 | 6.05 | 5.91 | 36.80% | CHEMBL1921962 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -4.44 | -1.46 | -2.39 | 49.37% | CHEMBL3672913 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | 2.04 | -0.16 | 2.63 | 28.52% | CHEMBL1585091 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | 3.39 | 3.35 | 5.68 | 33.20% | CHEMBL3560146 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 0.96 | 0.27 | 0.38 | 33.20% | CHEMBL3560146 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -4.68 | N/A | N/A | 49.52% | CHEMBL1783966 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.03 | -8.57 | -8.15 | 41.48% | CHEMBL3104091 | Active | 98.59% |
| HRH3_HUMAN | histamine receptor H3 | -7.05 | -8.66 | -8.59 | 50.23% | CHEMBL247933 | Active | 68.73% |
| HRH4_HUMAN | histamine receptor H4 | -8.39 | -7.91 | -7.71 | 41.55% | CHEMBL3236550 | Active | 57.06% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.31 | -7.44 | -6.86 | 50.22% | CHEMBL3421676 | Inactive | 50.27% |
| MC4R_HUMAN | melanocortin 4 receptor | -6.93 | -6.70 | -6.99 | 50.39% | CHEMBL1172249 | Inactive | 65.49% |
| MC5R_HUMAN | melanocortin 5 receptor | -5.17 | -7.43 | -4.49 | 50.22% | CHEMBL3421676 | Active | 51.09% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.46 | -7.78 | -7.25 | 50.21% | CHEMBL3421678 | Inactive | 57.68% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.32 | -7.64 | -7.35 | 50.45% | CHEMBL1766207 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -7.82 | -8.70 | -8.63 | 46.15% | CHEMBL1683150 | Inactive | 94.59% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.55 | -7.67 | -8.66 | 40.40% | CHEMBL1705499 | Inactive | 83.21% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -7.91 | -7.70 | -7.97 | 44.49% | CHEMBL3422516 | Inactive | 68.08% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -8.12 | -8.35 | -8.99 | 36.95% | CHEMBL1801360 | Inactive | 58.59% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.24 | -8.34 | -8.14 | 46.10% | CHEMBL204050 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.23 | -8.22 | -7.69 | 42.08% | CHEMBL2371910 | Inactive | 87.85% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.69 | -8.67 | -8.47 | 42.08% | CHEMBL2371910 | Inactive | 84.60% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -7.98 | -7.57 | -7.77 | 45.18% | CHEMBL3084877 | Inactive | 61.87% |
| OPRD_HUMAN | opioid receptor delta 1 | -7.08 | -6.88 | -6.92 | 100.00% | CHEMBL299031 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.54 | -7.85 | -8.41 | 57.71% | CHEMBL226113 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.24 | -7.20 | -7.63 | 64.11% | CHEMBL3892859 | Active | 59.23% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.41 | -7.16 | -7.36 | 64.02% | CHEMBL3326229 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.20 | -7.24 | -8.47 | 43.70% | CHEMBL319384 | Active | 76.78% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -9.33 | -9.32 | -9.25 | 44.29% | CHEMBL1872433 | Inactive | 54.03% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -8.08 | -9.91 | -7.15 | 33.47% | CHEMBL1589735 | Inactive | 93.68% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -7.94 | -7.31 | -7.92 | 44.11% | CHEMBL250974 | Inactive | 77.24% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -7.52 | -8.06 | -8.72 | 33.72% | CHEMBL3884667 | N/A | N/A |