| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | |||||
| CBD | 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -7.73 | -7.28 | -7.71 | 49.40% | CHEMBL146942 | Active | 54.27% |
| THC | 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.16 | -7.81 | -8.69 | 51.18% | CHEMBL29951 | Active | 60.04% |
| CBD | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.29 | -8.27 | -8.87 | 49.40% | CHEMBL146942 | N/A | N/A |
| THC | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.19 | -9.16 | -8.17 | 51.18% | CHEMBL29951 | N/A | N/A |
| CBD | 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.57 | -8.53 | -8.07 | 40.82% | CHEMBL26998 | N/A | N/A |
| THC | 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.18 | -8.69 | -8.20 | 51.18% | CHEMBL29951 | N/A | N/A |
| CBD | 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -7.73 | -7.70 | -7.67 | 27.39% | CHEMBL22744 | Active | 59.03% |
| THC | 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.65 | -8.38 | -8.25 | 24.59% | CHEMBL22744 | Inactive | 73.52% |
| CBD | 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -7.93 | -8.12 | -8.55 | 23.81% | CHEMBL497963 | Inactive | 67.89% |
| THC | 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -8.99 | -9.21 | -9.07 | 25.58% | CHEMBL3616488 | Inactive | 73.43% |
| CBD | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.25 | -8.22 | N/A | 46.74% | CHEMBL268890 | N/A | N/A |
| THC | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.60 | -9.36 | N/A | 49.54% | CHEMBL268890 | N/A | N/A |
| CBD | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -7.83 | -8.33 | -7.80 | 41.98% | CHEMBL510383 | N/A | N/A |
| THC | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -9.25 | -9.09 | -9.58 | 45.45% | CHEMBL2022186 | N/A | N/A |
| CBD | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.49 | -8.63 | N/A | 41.98% | CHEMBL510383 | N/A | N/A |
| THC | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.80 | -8.49 | N/A | 48.18% | CHEMBL2022189 | N/A | N/A |
| CBD | 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -8.28 | -8.80 | -8.66 | 31.06% | CHEMBL84398 | Inactive | 83.03% |
| THC | 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -9.82 | -9.35 | -8.85 | 35.56% | CHEMBL571799 | Inactive | 57.63% |
| CBD | 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.16 | -7.15 | -8.07 | 36.70% | CHEMBL278751 | Inactive | 59.09% |
| THC | 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.60 | -7.30 | -8.01 | 40.48% | CHEMBL278751 | Inactive | 66.83% |
| CBD | 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.65 | -7.87 | -8.61 | 49.40% | CHEMBL146942 | Active | 78.40% |
| THC | 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.33 | -7.82 | -9.05 | 43.83% | CHEMBL429023 | Active | 66.96% |
| CBD | 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -7.82 | -8.74 | -8.48 | 49.40% | CHEMBL146942 | Active | 72.23% |
| THC | 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -9.01 | -8.73 | -8.45 | 42.07% | CHEMBL2158029 | Active | 58.86% |
| CBD | AA1R_HUMAN | adenosine A1 receptor | -8.10 | -8.08 | -8.65 | 26.67% | CHEMBL103150 | N/A | N/A |
| THC | AA1R_HUMAN | adenosine A1 receptor | -8.91 | -8.76 | -8.50 | 27.66% | CHEMBL1544 | N/A | N/A |
| CBD | AA2AR_HUMAN | adenosine A2a receptor | -7.93 | -7.96 | -8.29 | 27.00% | CHEMBL496 | N/A | N/A |
| THC | AA2AR_HUMAN | adenosine A2a receptor | -8.35 | -8.66 | -9.07 | 27.21% | CHEMBL355390 | N/A | N/A |
| CBD | AA2BR_HUMAN | adenosine A2b receptor | -7.99 | -8.79 | -7.87 | 21.56% | CHEMBL3317578 | Inactive | 82.72% |
| THC | AA2BR_HUMAN | adenosine A2b receptor | -8.28 | -8.39 | -9.04 | 27.13% | CHEMBL3317575 | Inactive | 56.72% |
| CBD | AA3R_HUMAN | adenosine A3 receptor | -8.74 | -6.38 | -8.87 | 40.82% | CHEMBL56 | Inactive | 63.64% |
| THC | AA3R_HUMAN | adenosine A3 receptor | -9.35 | -6.37 | -9.16 | 47.62% | CHEMBL513389 | Active | 57.66% |
| CBD | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -9.17 | -5.09 | N/A | 41.90% | CHEMBL3085495 | N/A | N/A |
| THC | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.90 | -2.48 | N/A | 44.09% | CHEMBL343236 | N/A | N/A |
| CBD | ACM2_HUMAN | cholinergic receptor muscarinic 2 | -8.58 | -7.99 | -9.89 | 41.90% | CHEMBL3085495 | Active | 65.74% |
| THC | ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.51 | -8.72 | -10.52 | 44.09% | CHEMBL343236 | Active | 56.80% |
| CBD | ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.13 | -9.41 | -9.00 | 41.90% | CHEMBL3085495 | Active | 51.18% |
| THC | ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.44 | -9.97 | -9.23 | 41.60% | CHEMBL3085495 | Active | 50.42% |
| CBD | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.23 | -8.61 | N/A | 41.90% | CHEMBL3085495 | N/A | N/A |
| THC | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.01 | -8.51 | N/A | 41.60% | CHEMBL3085495 | N/A | N/A |
| CBD | ACM5_HUMAN | cholinergic receptor muscarinic 5 | -9.22 | -9.57 | -8.67 | 32.99% | CHEMBL27673 | Active | 62.87% |
| THC | ACM5_HUMAN | cholinergic receptor muscarinic 5 | -10.18 | -10.30 | -8.43 | 35.66% | CHEMBL490 | Active | 74.21% |
| CBD | ACTHR_HUMAN | melanocortin 2 receptor | -8.72 | -8.58 | -8.40 | N/A | N/A | N/A | N/A |
| THC | ACTHR_HUMAN | melanocortin 2 receptor | -10.67 | -10.30 | -9.77 | N/A | N/A | N/A | N/A |
| CBD | ADA1D_HUMAN | adrenoceptor alpha 1D | -8.45 | -8.12 | -9.02 | 40.82% | CHEMBL56 | Inactive | 65.06% |
| THC | ADA1D_HUMAN | adrenoceptor alpha 1D | -9.15 | -8.07 | -8.64 | 45.97% | CHEMBL101739 | Active | 58.88% |
| CBD | ADA2A_HUMAN | adrenoceptor alpha 2A | -7.00 | -5.57 | -4.98 | 34.75% | CHEMBL256984 | Active | 53.20% |
| THC | ADA2A_HUMAN | adrenoceptor alpha 2A | -7.69 | -8.78 | -4.39 | 47.62% | CHEMBL513389 | Inactive | 50.24% |
| CBD | ADA2B_HUMAN | adrenoceptor alpha 2B | -8.62 | -9.52 | -8.27 | 32.18% | CHEMBL1437 | Active | 53.34% |
| THC | ADA2B_HUMAN | adrenoceptor alpha 2B | -8.68 | -9.24 | -8.67 | 42.54% | CHEMBL179648 | Active | 69.59% |
| CBD | ADA2C_HUMAN | adrenoceptor alpha 2C | -2.17 | -1.70 | 0.49 | 32.81% | CHEMBL50588 | Inactive | 99.99% |
| THC | ADA2C_HUMAN | adrenoceptor alpha 2C | -1.80 | -1.14 | -0.22 | 42.54% | CHEMBL179648 | Inactive | 99.99% |
| CBD | ADRB1_HUMAN | adrenoceptor beta 1 | -8.85 | -8.16 | -9.37 | 32.48% | CHEMBL26917 | Inactive | 70.85% |
| THC | ADRB1_HUMAN | adrenoceptor beta 1 | -8.95 | -9.08 | -9.05 | 45.24% | CHEMBL26917 | Active | 75.48% |
| CBD | ADRB2_HUMAN | adrenoceptor beta 2 | -8.21 | -9.63 | -9.01 | 37.89% | CHEMBL1800960 | N/A | N/A |
| THC | ADRB2_HUMAN | adrenoceptor beta 2 | -8.00 | -9.88 | -9.58 | 47.62% | CHEMBL513389 | N/A | N/A |
| CBD | ADRB3_HUMAN | adrenoceptor beta 3 | -8.91 | -8.85 | -8.73 | 32.18% | CHEMBL1437 | N/A | N/A |
| THC | ADRB3_HUMAN | adrenoceptor beta 3 | -9.06 | -8.51 | -9.06 | 43.07% | CHEMBL1201237 | N/A | N/A |
| CBD | AGTR2_HUMAN | angiotensin II receptor type 2 | -8.25 | -8.51 | -8.20 | 25.84% | CHEMBL154057 | N/A | N/A |
| THC | AGTR2_HUMAN | angiotensin II receptor type 2 | -8.65 | -8.44 | -8.55 | 35.48% | CHEMBL154057 | N/A | N/A |
| CBD | BKRB2_HUMAN | bradykinin receptor B2 | -8.93 | -8.78 | -9.07 | 20.73% | CHEMBL1162797 | Inactive | 88.64% |
| THC | BKRB2_HUMAN | bradykinin receptor B2 | -9.18 | -8.94 | -8.85 | 21.68% | CHEMBL553530 | Inactive | 88.31% |
| CBD | CALCR_HUMAN | calcitonin receptor | -7.72 | -7.82 | -8.29 | 19.10% | CHEMBL2369895 | Inactive | 98.48% |
| THC | CALCR_HUMAN | calcitonin receptor | -7.85 | -8.62 | -8.12 | 18.18% | CHEMBL2369897 | Inactive | 98.85% |
| CBD | CCKAR_HUMAN | cholecystokinin A receptor | -8.17 | -7.16 | -8.24 | 20.27% | CHEMBL250974 | Inactive | 98.20% |
| THC | CCKAR_HUMAN | cholecystokinin A receptor | -9.25 | -8.36 | -8.68 | 25.00% | CHEMBL250974 | Inactive | 80.28% |
| CBD | CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.26 | -7.41 | -7.26 | 33.33% | CHEMBL341840 | Inactive | 94.99% |
| THC | CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.95 | -8.20 | -9.04 | 35.29% | CHEMBL2391795 | Inactive | 82.83% |
| CBD | CCR2_HUMAN | C-C motif chemokine receptor 2 | -6.67 | -8.25 | -7.16 | 51.58% | CHEMBL3754764 | Inactive | 79.00% |
| THC | CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.04 | -8.50 | -7.96 | 47.01% | CHEMBL3754764 | Inactive | 52.26% |
| CBD | CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.26 | -7.39 | -7.54 | 25.89% | CHEMBL1618631 | Inactive | 80.62% |
| THC | CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.81 | -7.30 | -7.88 | 32.21% | CHEMBL1907216 | Inactive | 62.01% |
| CBD | CCR5_HUMAN | C-C motif chemokine receptor 5 | -7.96 | -8.04 | -7.62 | 34.82% | CHEMBL468150 | Inactive | 91.75% |
| THC | CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.22 | -8.55 | -8.27 | 32.96% | CHEMBL2281967 | Inactive | 90.81% |
| CBD | CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.12 | -8.70 | -8.96 | 30.07% | CHEMBL1213917 | Inactive | 92.41% |
| THC | CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.51 | -9.10 | -10.00 | 40.79% | CHEMBL1213917 | Inactive | 75.86% |
| CBD | CNR1_HUMAN | cannabinoid receptor 1 | -7.64 | -8.55 | -9.38 | 98.61% | CHEMBL394305 | N/A | N/A |
| THC | CNR1_HUMAN | cannabinoid receptor 1 | -7.64 | -8.62 | -9.60 | 100.00% | CHEMBL600602 | N/A | N/A |
| CBD | CNR2_HUMAN | cannabinoid receptor 2 | -8.92 | -9.44 | N/A | 100.00% | CHEMBL236171 | N/A | N/A |
| THC | CNR2_HUMAN | cannabinoid receptor 2 | -10.09 | -9.84 | N/A | 100.00% | CHEMBL111148 | N/A | N/A |
| CBD | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.53 | N/A | N/A | 24.71% | CHEMBL254370 | N/A | N/A |
| THC | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.81 | N/A | N/A | 25.00% | CHEMBL220182 | N/A | N/A |
| CBD | CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -7.41 | -6.70 | -6.57 | 28.06% | CHEMBL3645131 | Inactive | 70.37% |
| THC | CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.03 | -7.34 | -7.18 | 40.14% | CHEMBL3645131 | Inactive | 54.90% |
| CBD | CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -7.87 | -8.06 | -7.99 | 32.26% | CHEMBL2205064 | Inactive | 96.43% |
| THC | CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.70 | -8.90 | -9.19 | 37.65% | CHEMBL3697086 | Inactive | 82.72% |
| CBD | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.19 | -6.79 | -7.11 | 32.14% | CHEMBL126657 | N/A | N/A |
| THC | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.56 | -7.88 | -7.20 | 31.34% | CHEMBL126657 | N/A | N/A |
| CBD | DRD1_HUMAN | dopamine receptor D1 | -8.57 | -7.87 | -7.85 | 42.86% | CHEMBL2092940 | Active | 51.09% |
| THC | DRD1_HUMAN | dopamine receptor D1 | -8.72 | -8.79 | -9.02 | 46.53% | CHEMBL3966718 | Active | 70.56% |
| CBD | DRD2_HUMAN | dopamine receptor D2 | -7.19 | N/A | N/A | 42.86% | CHEMBL1159663 | N/A | N/A |
| THC | DRD2_HUMAN | dopamine receptor D2 | -8.11 | N/A | N/A | 48.44% | CHEMBL64553 | N/A | N/A |
| CBD | DRD3_HUMAN | dopamine receptor D3 | -7.44 | N/A | N/A | 62.75% | CHEMBL4082631 | N/A | N/A |
| THC | DRD3_HUMAN | dopamine receptor D3 | -8.65 | N/A | N/A | 100.00% | CHEMBL465 | N/A | N/A |
| CBD | DRD4_HUMAN | dopamine receptor D4 | -8.03 | -8.64 | N/A | 40.82% | CHEMBL334472 | N/A | N/A |
| THC | DRD4_HUMAN | dopamine receptor D4 | -8.31 | -8.39 | N/A | 48.44% | CHEMBL64553 | N/A | N/A |
| CBD | DRD5_HUMAN | dopamine receptor D5 | -8.57 | -8.81 | -7.89 | 33.87% | CHEMBL604314 | Inactive | 64.89% |
| THC | DRD5_HUMAN | dopamine receptor D5 | -9.58 | -8.81 | -8.41 | 42.38% | CHEMBL217299 | Active | 79.38% |
| CBD | EDNRA_HUMAN | endothelin receptor type A | -7.23 | -6.98 | -7.03 | 36.73% | CHEMBL10832 | Inactive | 50.64% |
| THC | EDNRA_HUMAN | endothelin receptor type A | -7.56 | -7.68 | -8.06 | 43.15% | CHEMBL431651 | Inactive | 56.58% |
| CBD | GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -4.54 | -4.99 | 2.51 | 20.28% | CHEMBL2391908 | Inactive | 99.99% |
| THC | GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -3.01 | -2.53 | 4.66 | 21.95% | CHEMBL2391908 | Inactive | 99.99% |
| CBD | GASR_HUMAN | cholecystokinin B receptor | -8.51 | -7.32 | -5.81 | 24.46% | CHEMBL452991 | Inactive | 80.01% |
| THC | GASR_HUMAN | cholecystokinin B receptor | -8.10 | -7.85 | -6.86 | 39.67% | CHEMBL452991 | Inactive | 73.96% |
| CBD | GRM1_HUMAN | glutamate metabotropic receptor 1 | -7.32 | -9.06 | -7.26 | 33.65% | CHEMBL254372 | Inactive | 67.80% |
| THC | GRM1_HUMAN | glutamate metabotropic receptor 1 | -9.61 | -9.84 | -9.14 | 39.17% | CHEMBL254372 | Active | 59.68% |
| CBD | GRM2_HUMAN | glutamate metabotropic receptor 2 | -5.64 | -6.40 | -5.33 | 34.58% | CHEMBL341457 | Inactive | 65.74% |
| THC | GRM2_HUMAN | glutamate metabotropic receptor 2 | -5.22 | -4.25 | -4.56 | 45.04% | CHEMBL186584 | Inactive | 99.99% |
| CBD | GRM3_HUMAN | glutamate metabotropic receptor 3 | -5.32 | -7.61 | -8.47 | 37.00% | CHEMBL124483 | Inactive | 96.20% |
| THC | GRM3_HUMAN | glutamate metabotropic receptor 3 | -5.33 | -6.71 | -5.28 | 39.84% | CHEMBL341457 | Inactive | 53.02% |
| CBD | GRM4_HUMAN | glutamate metabotropic receptor 4 | -2.77 | -3.02 | -2.54 | 20.30% | CHEMBL2063423 | Inactive | 99.99% |
| THC | GRM4_HUMAN | glutamate metabotropic receptor 4 | -0.68 | -0.93 | -0.72 | 30.92% | CHEMBL2063423 | Inactive | 99.99% |
| CBD | GRM5_HUMAN | glutamate metabotropic receptor 5 | -9.83 | -6.99 | -6.88 | 34.58% | CHEMBL1289626 | N/A | N/A |
| THC | GRM5_HUMAN | glutamate metabotropic receptor 5 | -9.35 | -5.75 | -5.53 | 44.35% | CHEMBL1682820 | N/A | N/A |
| CBD | GRM6_HUMAN | glutamate metabotropic receptor 6 | -7.48 | -8.19 | -7.86 | 12.95% | CHEMBL4101970 | Inactive | 98.68% |
| THC | GRM6_HUMAN | glutamate metabotropic receptor 6 | -8.89 | -9.09 | -8.77 | 15.62% | CHEMBL2381641 | Inactive | 97.95% |
| CBD | GRM7_HUMAN | glutamate metabotropic receptor 7 | -2.92 | -4.30 | -2.40 | 30.58% | CHEMBL432038 | Inactive | 99.99% |
| THC | GRM7_HUMAN | glutamate metabotropic receptor 7 | -3.01 | -1.51 | -2.80 | 36.76% | CHEMBL432038 | Inactive | 99.99% |
| CBD | GRM8_HUMAN | glutamate metabotropic receptor 8 | -2.23 | -2.12 | -2.07 | 30.58% | CHEMBL432038 | Inactive | 99.99% |
| THC | GRM8_HUMAN | glutamate metabotropic receptor 8 | 0.65 | 0.75 | 2.39 | 36.76% | CHEMBL432038 | Inactive | 99.99% |
| CBD | HRH1_HUMAN | histamine receptor H1 | -6.01 | N/A | N/A | 41.90% | CHEMBL1101 | N/A | N/A |
| THC | HRH1_HUMAN | histamine receptor H1 | -4.63 | N/A | N/A | 41.60% | CHEMBL1101 | N/A | N/A |
| CBD | HRH2_HUMAN | histamine receptor H2 | -9.21 | -8.16 | -8.52 | 31.75% | CHEMBL490632 | Active | 95.81% |
| THC | HRH2_HUMAN | histamine receptor H2 | -9.14 | -8.77 | -8.68 | 38.57% | CHEMBL490632 | Active | 98.54% |
| CBD | HRH3_HUMAN | histamine receptor H3 | -8.13 | -8.25 | -7.89 | 37.74% | CHEMBL2375595 | Active | 55.46% |
| THC | HRH3_HUMAN | histamine receptor H3 | -7.80 | -9.27 | -9.03 | 52.07% | CHEMBL2013048 | Active | 69.42% |
| CBD | HRH4_HUMAN | histamine receptor H4 | -7.90 | -7.83 | -8.08 | 33.67% | CHEMBL1934066 | Inactive | 54.75% |
| THC | HRH4_HUMAN | histamine receptor H4 | -9.19 | -9.12 | -9.44 | 41.86% | CHEMBL1934062 | Active | 55.35% |
| CBD | MC3R_HUMAN | melanocortin 3 receptor | -8.65 | -8.80 | -7.51 | 24.18% | CHEMBL193715 | Inactive | 65.41% |
| THC | MC3R_HUMAN | melanocortin 3 receptor | -9.09 | -8.09 | -7.60 | 25.67% | CHEMBL192450 | Inactive | 69.87% |
| CBD | MC4R_HUMAN | melanocortin 4 receptor | -7.11 | -6.72 | -7.31 | 39.22% | CHEMBL1699592 | Inactive | 86.05% |
| THC | MC4R_HUMAN | melanocortin 4 receptor | -7.46 | -7.47 | -7.63 | 36.17% | CHEMBL578944 | Inactive | 83.33% |
| CBD | MC5R_HUMAN | melanocortin 5 receptor | -6.25 | -7.67 | -4.85 | 25.00% | CHEMBL3913861 | Inactive | 90.35% |
| THC | MC5R_HUMAN | melanocortin 5 receptor | -6.42 | -7.80 | -5.42 | 26.06% | CHEMBL3913861 | Inactive | 87.13% |
| CBD | MSHR_HUMAN | melanocortin 1 receptor | -7.99 | -7.85 | -8.33 | 23.13% | CHEMBL379054 | Inactive | 76.99% |
| THC | MSHR_HUMAN | melanocortin 1 receptor | -8.65 | -8.61 | -8.40 | 28.29% | CHEMBL442537 | Inactive | 77.20% |
| CBD | NK1R_HUMAN | tachykinin receptor 1 | -7.65 | -7.87 | -7.68 | 40.98% | CHEMBL2114439 | N/A | N/A |
| THC | NK1R_HUMAN | tachykinin receptor 1 | -8.17 | -8.51 | -7.78 | 40.91% | CHEMBL2112368 | N/A | N/A |
| CBD | NK2R_HUMAN | tachykinin receptor 2 | -8.10 | -8.30 | -8.02 | 29.59% | CHEMBL17157 | Inactive | 98.32% |
| THC | NK2R_HUMAN | tachykinin receptor 2 | -8.54 | -8.17 | -8.22 | 33.08% | CHEMBL221753 | Inactive | 95.98% |
| CBD | NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.44 | -7.28 | -7.10 | 21.98% | CHEMBL1940539 | Inactive | 96.04% |
| THC | NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.82 | -7.13 | -7.76 | 25.89% | CHEMBL2001553 | Inactive | 92.34% |
| CBD | NPFF1_HUMAN | neuropeptide FF receptor 1 | -7.30 | -7.07 | -7.17 | 26.45% | CHEMBL3361424 | Inactive | 93.87% |
| THC | NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.22 | -8.04 | -7.78 | 23.43% | CHEMBL2208334 | Inactive | 72.01% |
| CBD | NPSR1_HUMAN | neuropeptide S receptor 1 | -8.21 | -8.18 | -8.07 | 22.66% | CHEMBL3086828 | Inactive | 78.41% |
| THC | NPSR1_HUMAN | neuropeptide S receptor 1 | -8.99 | -9.76 | -8.54 | 30.73% | CHEMBL1801359 | Inactive | 58.33% |
| CBD | NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.06 | -8.36 | -7.47 | 32.46% | CHEMBL556915 | N/A | N/A |
| THC | NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.24 | -8.84 | -8.78 | 40.19% | CHEMBL3559801 | N/A | N/A |
| CBD | NPY2R_HUMAN | neuropeptide Y receptor Y2 | -7.54 | -8.22 | -7.47 | 28.42% | CHEMBL3559801 | Inactive | 96.96% |
| THC | NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.26 | -8.11 | -7.95 | 40.19% | CHEMBL3559801 | Inactive | 94.45% |
| CBD | NPY4R_HUMAN | neuropeptide Y receptor Y4 | -7.98 | -8.49 | -8.02 | 28.42% | CHEMBL3559801 | Inactive | 71.65% |
| THC | NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.54 | -8.73 | -8.14 | 40.19% | CHEMBL3559801 | Inactive | 83.66% |
| CBD | NPY5R_HUMAN | neuropeptide Y receptor Y5 | -7.65 | -7.51 | -7.44 | 45.00% | CHEMBL469257 | Inactive | 85.48% |
| THC | NPY5R_HUMAN | neuropeptide Y receptor Y5 | -7.96 | -7.85 | -8.01 | 61.54% | CHEMBL469257 | Active | 93.46% |
| CBD | OPRD_HUMAN | opioid receptor delta 1 | -7.14 | -6.74 | -6.98 | 45.54% | CHEMBL437949 | N/A | N/A |
| THC | OPRD_HUMAN | opioid receptor delta 1 | -8.84 | -7.10 | -7.43 | 49.11% | CHEMBL410907 | N/A | N/A |
| CBD | OPRK_HUMAN | opioid receptor kappa 1 | -8.68 | -9.16 | -7.97 | 45.54% | CHEMBL437949 | N/A | N/A |
| THC | OPRK_HUMAN | opioid receptor kappa 1 | -9.48 | -8.81 | -8.28 | 49.11% | CHEMBL410907 | N/A | N/A |
| CBD | OPRM_HUMAN | opioid receptor mu 1 | -8.03 | -7.89 | -7.13 | 45.54% | CHEMBL437949 | Inactive | 59.36% |
| THC | OPRM_HUMAN | opioid receptor mu 1 | -9.41 | -6.94 | -8.54 | 49.11% | CHEMBL410907 | Inactive | 61.36% |
| CBD | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.56 | -7.51 | -7.81 | 37.50% | CHEMBL3785718 | N/A | N/A |
| THC | OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.21 | -8.33 | -9.02 | 44.27% | CHEMBL3262362 | N/A | N/A |
| CBD | PTAFR_HUMAN | platelet activating factor receptor | -8.04 | -8.30 | -7.67 | 37.74% | CHEMBL297624 | Inactive | 56.10% |
| THC | PTAFR_HUMAN | platelet activating factor receptor | -8.31 | -9.23 | -8.49 | 43.80% | CHEMBL297624 | Active | 59.37% |
| CBD | TAAR1_HUMAN | trace amine associated receptor 1 | -9.19 | -8.75 | -8.43 | 33.75% | CHEMBL1200705 | Active | 62.09% |
| THC | TAAR1_HUMAN | trace amine associated receptor 1 | -9.40 | -9.37 | -9.65 | 38.12% | CHEMBL1732597 | Inactive | 67.15% |
| CBD | TSHR_HUMAN | thyroid stimulating hormone receptor | -8.66 | -9.61 | -8.28 | 23.56% | CHEMBL3897841 | Inactive | 97.26% |
| THC | TSHR_HUMAN | thyroid stimulating hormone receptor | -10.18 | -10.03 | -10.32 | 23.35% | CHEMBL3897841 | Inactive | 81.87% |
| CBD | V1AR_HUMAN | arginine vasopressin receptor 1A | -8.17 | -7.26 | -8.29 | 33.77% | CHEMBL430676 | Inactive | 82.09% |
| THC | V1AR_HUMAN | arginine vasopressin receptor 1A | -8.45 | -7.71 | -9.06 | 33.72% | CHEMBL430676 | Inactive | 89.28% |
| CBD | VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -7.74 | -8.00 | -8.22 | 18.23% | CHEMBL483749 | N/A | N/A |
| THC | VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.74 | -8.97 | -8.47 | 18.06% | CHEMBL483749 | N/A | N/A |