| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||||
| bictegravir | GP160_HIV1 | Envelope glycoprotein gp160 | -8.02 | -8.18 | -7.38 | N/A | N/A |
| emtricitabine | GP160_HIV1 | Envelope glycoprotein gp160 | -5.84 | -5.91 | -5.27 | N/A | N/A |
| tenofovir alafenamide | GP160_HIV1 | Envelope glycoprotein gp160 | -7.16 | -6.60 | -6.68 | N/A | N/A |
| bictegravir | GP160_HIV2 | Envelope glycoprotein gp160 | -8.60 | N/A | N/A | N/A | N/A |
| emtricitabine | GP160_HIV2 | Envelope glycoprotein gp160 | -4.99 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | GP160_HIV2 | Envelope glycoprotein gp160 | -6.84 | N/A | N/A | N/A | N/A |
| bictegravir | GP_EBOV | Envelope glycoprotein | -9.34 | -9.70 | -8.73 | 31.95% | CHEMBL3125895 |
| emtricitabine | GP_EBOV | Envelope glycoprotein | -5.60 | -5.51 | -5.24 | 22.11% | CHEMBL3125899 |
| tenofovir alafenamide | GP_EBOV | Envelope glycoprotein | -7.06 | -6.92 | -7.48 | 18.69% | CHEMBL3125895 |
| bictegravir | HA_A-H10N7 | Hemagglutinin | -8.76 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H10N7 | Hemagglutinin | -5.67 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H10N7 | Hemagglutinin | -6.75 | N/A | N/A | N/A | N/A |
| bictegravir | HA_A-H10N8 | Hemagglutinin | -7.43 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H10N8 | Hemagglutinin | -5.39 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H10N8 | Hemagglutinin | -6.29 | N/A | N/A | N/A | N/A |
| bictegravir | HA_A-H13N6 | Hemagglutinin | -8.31 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H13N6 | Hemagglutinin | -5.72 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H13N6 | Hemagglutinin | -6.09 | N/A | N/A | N/A | N/A |
| bictegravir | HA_A-H14N6 | Hemagglutinin | -8.90 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H14N6 | Hemagglutinin | -5.94 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H14N6 | Hemagglutinin | -6.00 | N/A | N/A | N/A | N/A |
| bictegravir | HA_A-H15N9 | Hemagglutinin | -8.31 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H15N9 | Hemagglutinin | -5.94 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H15N9 | Hemagglutinin | -6.42 | N/A | N/A | N/A | N/A |
| bictegravir | HA_A-H17N10 | Hemagglutinin | -7.25 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H17N10 | Hemagglutinin | -5.17 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H17N10 | Hemagglutinin | -6.02 | N/A | N/A | N/A | N/A |
| bictegravir | HA_A-H18N11 | Hemagglutinin | -6.53 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H18N11 | Hemagglutinin | -5.36 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H18N11 | Hemagglutinin | -5.62 | N/A | N/A | N/A | N/A |
| bictegravir | HA_A-H1N1 | Hemagglutinin | -7.81 | -7.91 | N/A | N/A | N/A |
| emtricitabine | HA_A-H1N1 | Hemagglutinin | -5.45 | -5.51 | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H1N1 | Hemagglutinin | -6.20 | -6.06 | N/A | N/A | N/A |
| bictegravir | HA_A-H2N2 | Hemagglutinin | -7.84 | -7.01 | N/A | N/A | N/A |
| emtricitabine | HA_A-H2N2 | Hemagglutinin | -5.09 | -5.39 | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H2N2 | Hemagglutinin | -5.53 | -5.78 | N/A | N/A | N/A |
| bictegravir | HA_A-H3N2 | Hemagglutinin | -8.23 | -8.29 | -8.04 | N/A | N/A |
| emtricitabine | HA_A-H3N2 | Hemagglutinin | -5.61 | -5.44 | -5.19 | N/A | N/A |
| tenofovir alafenamide | HA_A-H3N2 | Hemagglutinin | -6.60 | -6.34 | -5.58 | N/A | N/A |
| bictegravir | HA_A-H3N8 | Hemagglutinin | -7.32 | -7.63 | -7.35 | N/A | N/A |
| emtricitabine | HA_A-H3N8 | Hemagglutinin | -5.07 | -5.12 | -5.08 | N/A | N/A |
| tenofovir alafenamide | HA_A-H3N8 | Hemagglutinin | -5.61 | -5.56 | -6.08 | N/A | N/A |
| bictegravir | HA_A-H5N1 | Hemagglutinin | -8.51 | -8.10 | -8.04 | N/A | N/A |
| emtricitabine | HA_A-H5N1 | Hemagglutinin | -6.23 | -5.50 | -5.71 | N/A | N/A |
| tenofovir alafenamide | HA_A-H5N1 | Hemagglutinin | -5.91 | -6.32 | -6.34 | N/A | N/A |
| bictegravir | HA_A-H5N3 | Hemagglutinin | -7.28 | -8.14 | N/A | N/A | N/A |
| emtricitabine | HA_A-H5N3 | Hemagglutinin | -6.08 | -5.60 | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H5N3 | Hemagglutinin | -5.73 | -5.86 | N/A | N/A | N/A |
| bictegravir | HA_A-H6N1 | Hemagglutinin | -7.43 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H6N1 | Hemagglutinin | -5.39 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H6N1 | Hemagglutinin | -6.29 | N/A | N/A | N/A | N/A |
| bictegravir | HA_A-H6N6 | Hemagglutinin | -7.89 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H6N6 | Hemagglutinin | -5.16 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H6N6 | Hemagglutinin | -6.37 | N/A | N/A | N/A | N/A |
| bictegravir | HA_A-H7N2 | Hemagglutinin | -7.41 | -7.32 | -7.32 | N/A | N/A |
| emtricitabine | HA_A-H7N2 | Hemagglutinin | -5.39 | -5.00 | -5.27 | N/A | N/A |
| tenofovir alafenamide | HA_A-H7N2 | Hemagglutinin | -5.79 | -6.07 | -6.31 | N/A | N/A |
| bictegravir | HA_A-H7N7 | Hemagglutinin | -7.31 | -8.91 | N/A | N/A | N/A |
| emtricitabine | HA_A-H7N7 | Hemagglutinin | -5.19 | -5.82 | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H7N7 | Hemagglutinin | -5.53 | -6.77 | N/A | N/A | N/A |
| bictegravir | HA_A-H7N9 | Hemagglutinin | -7.74 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_A-H7N9 | Hemagglutinin | -5.63 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_A-H7N9 | Hemagglutinin | -6.13 | N/A | N/A | N/A | N/A |
| bictegravir | HA_INFB | Hemagglutinin | -7.97 | -8.24 | N/A | N/A | N/A |
| emtricitabine | HA_INFB | Hemagglutinin | -5.64 | -5.75 | N/A | N/A | N/A |
| tenofovir alafenamide | HA_INFB | Hemagglutinin | -6.41 | -6.17 | N/A | N/A | N/A |
| bictegravir | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -6.75 | N/A | N/A | N/A | N/A |
| emtricitabine | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -4.61 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -6.02 | N/A | N/A | N/A | N/A |
| bictegravir | HE_BCV | Hemagglutinin-esterase | -8.44 | -7.89 | N/A | N/A | N/A |
| emtricitabine | HE_BCV | Hemagglutinin-esterase | -6.69 | -6.14 | N/A | N/A | N/A |
| tenofovir alafenamide | HE_BCV | Hemagglutinin-esterase | -6.57 | -6.10 | N/A | N/A | N/A |
| bictegravir | HE_HCoV-OC43 | Hemagglutinin-esterase | -7.02 | N/A | N/A | N/A | N/A |
| emtricitabine | HE_HCoV-OC43 | Hemagglutinin-esterase | -5.08 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HE_HCoV-OC43 | Hemagglutinin-esterase | -5.85 | N/A | N/A | N/A | N/A |
| bictegravir | HE_MHV | Hemagglutinin-esterase | -7.29 | N/A | N/A | N/A | N/A |
| emtricitabine | HE_MHV | Hemagglutinin-esterase | -4.87 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | HE_MHV | Hemagglutinin-esterase | -5.57 | N/A | N/A | N/A | N/A |
| bictegravir | IN_HIV1 | Gag-Pol polyprotein | -6.27 | -7.20 | N/A | N/A | N/A |
| emtricitabine | IN_HIV1 | Gag-Pol polyprotein | -4.30 | -4.45 | N/A | N/A | N/A |
| tenofovir alafenamide | IN_HIV1 | Gag-Pol polyprotein | -5.55 | -5.49 | N/A | N/A | N/A |
| bictegravir | MD_HKU4 | Replicase polyprotein 1ab | -10.19 | -10.05 | -10.16 | N/A | N/A |
| emtricitabine | MD_HKU4 | Replicase polyprotein 1ab | -6.20 | -5.99 | -5.94 | N/A | N/A |
| tenofovir alafenamide | MD_HKU4 | Replicase polyprotein 1ab | -7.59 | -8.09 | -7.73 | N/A | N/A |
| bictegravir | MD_MERs | Replicase polyprotein 1a | -10.38 | -10.08 | N/A | N/A | N/A |
| emtricitabine | MD_MERs | Replicase polyprotein 1a | -6.63 | -6.32 | N/A | N/A | N/A |
| tenofovir alafenamide | MD_MERs | Replicase polyprotein 1a | -8.44 | -8.22 | N/A | N/A | N/A |
| bictegravir | MX2_A-H5N1 | Matrix protein 2 | -10.01 | N/A | N/A | N/A | N/A |
| emtricitabine | MX2_A-H5N1 | Matrix protein 2 | -8.23 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | MX2_A-H5N1 | Matrix protein 2 | -6.49 | N/A | N/A | N/A | N/A |
| bictegravir | NA_A-H11N6 | Neuraminidase | -9.92 | -9.55 | -9.60 | N/A | N/A |
| emtricitabine | NA_A-H11N6 | Neuraminidase | -6.96 | -6.89 | -6.64 | N/A | N/A |
| tenofovir alafenamide | NA_A-H11N6 | Neuraminidase | -7.56 | -7.62 | -7.32 | N/A | N/A |
| bictegravir | NA_A-H11N9 | Neuraminidase | -8.21 | -9.74 | -9.42 | N/A | N/A |
| emtricitabine | NA_A-H11N9 | Neuraminidase | -5.60 | -6.68 | -6.64 | N/A | N/A |
| tenofovir alafenamide | NA_A-H11N9 | Neuraminidase | -5.41 | -7.07 | -7.16 | N/A | N/A |
| bictegravir | NA_A-H12N5 | Neuraminidase | -9.74 | -9.61 | -9.66 | N/A | N/A |
| emtricitabine | NA_A-H12N5 | Neuraminidase | -6.64 | -6.99 | -7.00 | N/A | N/A |
| tenofovir alafenamide | NA_A-H12N5 | Neuraminidase | -6.86 | -7.35 | -7.15 | N/A | N/A |
| bictegravir | NA_A-H13N9 | Neuraminidase | -8.35 | N/A | N/A | N/A | N/A |
| emtricitabine | NA_A-H13N9 | Neuraminidase | -6.57 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NA_A-H13N9 | Neuraminidase | -6.68 | N/A | N/A | N/A | N/A |
| bictegravir | NA_A-H17N10 | Neuraminidase | -9.07 | N/A | N/A | N/A | N/A |
| emtricitabine | NA_A-H17N10 | Neuraminidase | -5.56 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NA_A-H17N10 | Neuraminidase | -7.05 | N/A | N/A | N/A | N/A |
| bictegravir | NA_A-H18N11 | Neuraminidase | -8.37 | N/A | N/A | N/A | N/A |
| emtricitabine | NA_A-H18N11 | Neuraminidase | -5.33 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NA_A-H18N11 | Neuraminidase | -6.26 | N/A | N/A | N/A | N/A |
| bictegravir | NA_A-H1N1 | Neuraminidase | -9.58 | N/A | N/A | N/A | N/A |
| emtricitabine | NA_A-H1N1 | Neuraminidase | -6.34 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NA_A-H1N1 | Neuraminidase | -7.27 | N/A | N/A | N/A | N/A |
| bictegravir | NA_A-H2N2 | Neuraminidase | -8.68 | -10.03 | -9.34 | N/A | N/A |
| emtricitabine | NA_A-H2N2 | Neuraminidase | -6.65 | -6.33 | -6.22 | N/A | N/A |
| tenofovir alafenamide | NA_A-H2N2 | Neuraminidase | -7.05 | -7.14 | -6.96 | N/A | N/A |
| bictegravir | NA_A-H3N2 | Ig heavy chain Mem5 | -9.29 | -9.28 | N/A | N/A | N/A |
| emtricitabine | NA_A-H3N2 | Ig heavy chain Mem5 | -5.48 | -5.47 | N/A | N/A | N/A |
| tenofovir alafenamide | NA_A-H3N2 | Ig heavy chain Mem5 | -6.72 | -7.27 | N/A | N/A | N/A |
| bictegravir | NA_A-H3N8 | Neuraminidase | -9.62 | -9.33 | -10.04 | N/A | N/A |
| emtricitabine | NA_A-H3N8 | Neuraminidase | -6.59 | -6.46 | -6.78 | N/A | N/A |
| tenofovir alafenamide | NA_A-H3N8 | Neuraminidase | -7.07 | -7.59 | -7.50 | N/A | N/A |
| bictegravir | NA_A-H5N1 | Neuraminidase | -9.17 | N/A | N/A | N/A | N/A |
| emtricitabine | NA_A-H5N1 | Neuraminidase | -6.36 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NA_A-H5N1 | Neuraminidase | -8.00 | N/A | N/A | N/A | N/A |
| bictegravir | NA_A-H7N9 | Neuraminidase | -9.64 | -9.85 | -9.61 | N/A | N/A |
| emtricitabine | NA_A-H7N9 | Neuraminidase | -6.38 | -6.69 | -6.83 | N/A | N/A |
| tenofovir alafenamide | NA_A-H7N9 | Neuraminidase | -7.03 | -7.69 | -6.98 | N/A | N/A |
| bictegravir | NA_INFB | Neuraminidase | -8.98 | -8.55 | N/A | 31.12% | CHEMBL4175983 |
| emtricitabine | NA_INFB | Neuraminidase | -6.57 | -6.99 | N/A | 16.75% | CHEMBL195288 |
| tenofovir alafenamide | NA_INFB | Neuraminidase | -7.17 | -7.42 | N/A | 17.37% | CHEMBL183817 |
| bictegravir | NP_A-H1N1 | Nucleoprotein | -7.85 | -8.37 | -8.73 | N/A | N/A |
| emtricitabine | NP_A-H1N1 | Nucleoprotein | -5.20 | -5.17 | -6.90 | N/A | N/A |
| tenofovir alafenamide | NP_A-H1N1 | Nucleoprotein | -5.47 | -7.18 | -5.77 | N/A | N/A |
| bictegravir | NP_A-H5N1 | Nucleoprotein | -8.04 | N/A | N/A | N/A | N/A |
| emtricitabine | NP_A-H5N1 | Nucleoprotein | -6.13 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NP_A-H5N1 | Nucleoprotein | -6.34 | N/A | N/A | N/A | N/A |
| bictegravir | NP_HCoV-NL63 | Nucleoprotein | -9.22 | N/A | N/A | N/A | N/A |
| emtricitabine | NP_HCoV-NL63 | Nucleoprotein | -5.76 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NP_HCoV-NL63 | Nucleoprotein | -6.67 | N/A | N/A | N/A | N/A |
| bictegravir | NP_HCoV-OC43 | Nucleoprotein | -11.95 | -8.99 | -8.08 | 15.54% | CHEMBL3233481 |
| emtricitabine | NP_HCoV-OC43 | Nucleoprotein | -6.49 | -5.77 | -5.85 | 13.07% | CHEMBL3233481 |
| tenofovir alafenamide | NP_HCoV-OC43 | Nucleoprotein | -7.65 | -7.49 | -6.52 | 9.22% | CHEMBL3233481 |
| bictegravir | NP_INFB | Nucleoprotein | -6.17 | N/A | N/A | N/A | N/A |
| emtricitabine | NP_INFB | Nucleoprotein | -4.49 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NP_INFB | Nucleoprotein | -5.61 | N/A | N/A | N/A | N/A |
| bictegravir | NP_INFD | NP | -6.72 | N/A | N/A | N/A | N/A |
| emtricitabine | NP_INFD | NP | -4.36 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NP_INFD | NP | -5.45 | N/A | N/A | N/A | N/A |
| bictegravir | NP_SARS | Nucleoprotein | -9.04 | N/A | N/A | N/A | N/A |
| emtricitabine | NP_SARS | Nucleoprotein | -6.03 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NP_SARS | Nucleoprotein | -6.66 | N/A | N/A | N/A | N/A |
| bictegravir | NS3_HCV1A | Genome polyprotein | -7.77 | -7.76 | -9.84 | 37.41% | CHEMBL3645743 |
| emtricitabine | NS3_HCV1A | Genome polyprotein | -6.22 | -6.32 | -6.27 | 34.41% | CHEMBL3696815 |
| tenofovir alafenamide | NS3_HCV1A | Genome polyprotein | -6.18 | -5.83 | -7.48 | 44.94% | CHEMBL3696815 |
| bictegravir | NS3_HCV1B | Genome polyprotein | -10.06 | -10.79 | -7.31 | 35.82% | CHEMBL3954962 |
| emtricitabine | NS3_HCV1B | Genome polyprotein | -6.24 | -6.01 | -5.93 | 20.56% | CHEMBL3125634 |
| tenofovir alafenamide | NS3_HCV1B | Genome polyprotein | -6.95 | -8.03 | -5.84 | 16.92% | CHEMBL1170417 |
| bictegravir | NS3_HCV3A | Genome polyprotein | -9.34 | -9.04 | -7.87 | N/A | N/A |
| emtricitabine | NS3_HCV3A | Genome polyprotein | -6.00 | -6.01 | -5.77 | N/A | N/A |
| tenofovir alafenamide | NS3_HCV3A | Genome polyprotein | -6.71 | -6.96 | -6.82 | N/A | N/A |
| bictegravir | NS5B_HCV1A | Genome polyprotein | -10.61 | -9.96 | -10.18 | 36.11% | CHEMBL3644880 |
| emtricitabine | NS5B_HCV1A | Genome polyprotein | -6.38 | -6.37 | -6.53 | 22.30% | CHEMBL3644940 |
| tenofovir alafenamide | NS5B_HCV1A | Genome polyprotein | -7.22 | -7.62 | -8.26 | 20.87% | CHEMBL3644940 |
| bictegravir | NS5B_HCV1B | Genome polyprotein | -9.58 | -9.62 | -8.92 | 36.31% | CHEMBL3645214 |
| emtricitabine | NS5B_HCV1B | Genome polyprotein | -5.70 | -5.61 | -5.97 | 20.42% | CHEMBL3645211 |
| tenofovir alafenamide | NS5B_HCV1B | Genome polyprotein | -7.61 | -7.53 | -7.52 | 23.15% | CHEMBL4111989 |
| bictegravir | NS5B_HCV2A | Genome polyprotein | -11.00 | -10.69 | N/A | N/A | N/A |
| emtricitabine | NS5B_HCV2A | Genome polyprotein | -6.82 | -7.13 | N/A | N/A | N/A |
| tenofovir alafenamide | NS5B_HCV2A | Genome polyprotein | -8.96 | -9.23 | N/A | N/A | N/A |
| bictegravir | NSP15_SARS | Replicase polyprotein 1ab | -7.79 | N/A | N/A | 24.29% | CHEMBL2441745 |
| emtricitabine | NSP15_SARS | Replicase polyprotein 1ab | -5.78 | N/A | N/A | 15.25% | CHEMBL2441745 |
| tenofovir alafenamide | NSP15_SARS | Replicase polyprotein 1ab | -6.44 | N/A | N/A | 15.61% | CHEMBL2441741 |
| bictegravir | NSP1_INFB | Non-structural protein 1 | -7.15 | -7.45 | N/A | N/A | N/A |
| emtricitabine | NSP1_INFB | Non-structural protein 1 | -4.25 | -4.40 | N/A | N/A | N/A |
| tenofovir alafenamide | NSP1_INFB | Non-structural protein 1 | -5.48 | -5.94 | N/A | N/A | N/A |
| bictegravir | NSP1_SARS | Replicase polyprotein 1ab | -8.13 | N/A | N/A | 24.29% | CHEMBL2441745 |
| emtricitabine | NSP1_SARS | Replicase polyprotein 1ab | -5.60 | N/A | N/A | 15.25% | CHEMBL2441745 |
| tenofovir alafenamide | NSP1_SARS | Replicase polyprotein 1ab | -5.93 | N/A | N/A | 15.61% | CHEMBL2441741 |
| bictegravir | NSP3_HCoV-229E | Replicase polyprotein 1a | -11.83 | N/A | N/A | N/A | N/A |
| emtricitabine | NSP3_HCoV-229E | Replicase polyprotein 1a | -6.39 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NSP3_HCoV-229E | Replicase polyprotein 1a | -8.69 | N/A | N/A | N/A | N/A |
| bictegravir | NSP3_IBV | Replicase polyprotein 1a | -10.98 | N/A | N/A | N/A | N/A |
| emtricitabine | NSP3_IBV | Replicase polyprotein 1a | -6.13 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NSP3_IBV | Replicase polyprotein 1a | -8.09 | N/A | N/A | N/A | N/A |
| bictegravir | NSP3_MHV | Replicase polyprotein 1ab | -7.29 | N/A | N/A | N/A | N/A |
| emtricitabine | NSP3_MHV | Replicase polyprotein 1ab | -5.22 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | NSP3_MHV | Replicase polyprotein 1ab | -6.28 | N/A | N/A | N/A | N/A |
| bictegravir | NSP9_HCoV-229E | Replicase polyprotein 1ab | -8.08 | -8.22 | N/A | N/A | N/A |
| emtricitabine | NSP9_HCoV-229E | Replicase polyprotein 1ab | -5.02 | -5.33 | N/A | N/A | N/A |
| tenofovir alafenamide | NSP9_HCoV-229E | Replicase polyprotein 1ab | -6.45 | -6.23 | N/A | N/A | N/A |
| bictegravir | PA_A-H17N10 | Polymerase acidic protein | -9.52 | N/A | N/A | N/A | N/A |
| emtricitabine | PA_A-H17N10 | Polymerase acidic protein | -5.91 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PA_A-H17N10 | Polymerase acidic protein | -6.90 | N/A | N/A | N/A | N/A |
| bictegravir | PA_A-H1N1 | Polymerase acidic protein | -10.75 | -9.31 | -10.06 | N/A | N/A |
| emtricitabine | PA_A-H1N1 | Polymerase acidic protein | -5.90 | -6.12 | -6.38 | N/A | N/A |
| tenofovir alafenamide | PA_A-H1N1 | Polymerase acidic protein | -7.73 | -7.49 | -7.52 | N/A | N/A |
| bictegravir | PA_A-H5N1 | Polymerase acidic protein | -10.31 | -10.27 | -10.01 | N/A | N/A |
| emtricitabine | PA_A-H5N1 | Polymerase acidic protein | -6.27 | -6.16 | -6.36 | N/A | N/A |
| tenofovir alafenamide | PA_A-H5N1 | Polymerase acidic protein | -7.56 | -7.29 | -7.95 | N/A | N/A |
| bictegravir | PA_INFA | Polymerase acidic protein | -11.04 | -9.45 | -9.72 | 30.00% | CHEMBL2040578 |
| emtricitabine | PA_INFA | Polymerase acidic protein | -6.37 | -6.14 | -5.88 | 19.07% | CHEMBL2040569 |
| tenofovir alafenamide | PA_INFA | Polymerase acidic protein | -8.48 | -7.26 | -7.67 | 15.56% | CHEMBL2040578 |
| bictegravir | PA_INFB | Polymerase acidic protein | -9.27 | N/A | N/A | N/A | N/A |
| emtricitabine | PA_INFB | Polymerase acidic protein | -5.79 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PA_INFB | Polymerase acidic protein | -7.52 | N/A | N/A | N/A | N/A |
| bictegravir | PB2_A-H3N2 | Polymerase basic protein 2 | -9.42 | -10.01 | N/A | N/A | N/A |
| emtricitabine | PB2_A-H3N2 | Polymerase basic protein 2 | -5.62 | -6.16 | N/A | N/A | N/A |
| tenofovir alafenamide | PB2_A-H3N2 | Polymerase basic protein 2 | -7.16 | -7.45 | N/A | N/A | N/A |
| bictegravir | PB2_A-H5N1 | Polymerase basic protein 2 | -7.99 | -9.47 | -9.20 | N/A | N/A |
| emtricitabine | PB2_A-H5N1 | Polymerase basic protein 2 | -6.09 | -5.77 | -6.38 | N/A | N/A |
| tenofovir alafenamide | PB2_A-H5N1 | Polymerase basic protein 2 | -6.75 | -6.57 | -7.86 | N/A | N/A |
| bictegravir | PB2_INFB | Polymerase basic protein 2 | -9.64 | N/A | N/A | N/A | N/A |
| emtricitabine | PB2_INFB | Polymerase basic protein 2 | -6.14 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PB2_INFB | Polymerase basic protein 2 | -6.64 | N/A | N/A | N/A | N/A |
| bictegravir | PB3_A-H3N2 | Polymerase basic protein 2 | -8.72 | N/A | N/A | N/A | N/A |
| emtricitabine | PB3_A-H3N2 | Polymerase basic protein 2 | -5.97 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PB3_A-H3N2 | Polymerase basic protein 2 | -6.94 | N/A | N/A | N/A | N/A |
| bictegravir | PB4_A-H3N2 | Polymerase basic protein 2 | -9.98 | N/A | N/A | N/A | N/A |
| emtricitabine | PB4_A-H3N2 | Polymerase basic protein 2 | -6.30 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PB4_A-H3N2 | Polymerase basic protein 2 | -7.26 | N/A | N/A | N/A | N/A |
| bictegravir | PLP_SARS | Replicase polyprotein 1a | -10.77 | -10.34 | -10.68 | 29.32% | CHEMBL213054 |
| emtricitabine | PLP_SARS | Replicase polyprotein 1a | -6.20 | -7.48 | -6.68 | 19.52% | CHEMBL212218 |
| tenofovir alafenamide | PLP_SARS | Replicase polyprotein 1a | -7.61 | -7.58 | -7.91 | 17.72% | CHEMBL213054 |
| bictegravir | PR_FCoV | Replicase polyprotein 1ab | -9.64 | N/A | N/A | N/A | N/A |
| emtricitabine | PR_FCoV | Replicase polyprotein 1ab | -5.68 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PR_FCoV | Replicase polyprotein 1ab | -7.01 | N/A | N/A | N/A | N/A |
| bictegravir | PR_HCoV-229E | Replicase polyprotein 1a | -9.47 | -8.63 | N/A | N/A | N/A |
| emtricitabine | PR_HCoV-229E | Replicase polyprotein 1a | -5.53 | -5.64 | N/A | N/A | N/A |
| tenofovir alafenamide | PR_HCoV-229E | Replicase polyprotein 1a | -6.99 | -7.15 | N/A | N/A | N/A |
| bictegravir | PR_HCoV-NL63 | Replicase polyprotein 1a | -5.32 | -9.41 | N/A | N/A | N/A |
| emtricitabine | PR_HCoV-NL63 | Replicase polyprotein 1a | -4.74 | -6.11 | N/A | N/A | N/A |
| tenofovir alafenamide | PR_HCoV-NL63 | Replicase polyprotein 1a | -4.76 | -7.27 | N/A | N/A | N/A |
| bictegravir | PR_HIV1 | Gag-Pol polyprotein | -8.44 | -8.43 | -7.97 | 25.83% | CHEMBL3645128 |
| emtricitabine | PR_HIV1 | Gag-Pol polyprotein | -5.12 | -5.40 | -5.56 | 23.24% | CHEMBL449291 |
| tenofovir alafenamide | PR_HIV1 | Gag-Pol polyprotein | -5.60 | -6.07 | -5.84 | 18.56% | CHEMBL450294 |
| bictegravir | PR_HIV2 | Gag-Pol polyprotein | -8.90 | -8.45 | N/A | N/A | N/A |
| emtricitabine | PR_HIV2 | Gag-Pol polyprotein | -5.59 | -5.13 | N/A | N/A | N/A |
| tenofovir alafenamide | PR_HIV2 | Gag-Pol polyprotein | -6.51 | -6.31 | N/A | N/A | N/A |
| bictegravir | PR_HKU1 | Replicase polyprotein 1a | -8.52 | N/A | N/A | N/A | N/A |
| emtricitabine | PR_HKU1 | Replicase polyprotein 1a | -5.67 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PR_HKU1 | Replicase polyprotein 1a | -6.39 | N/A | N/A | N/A | N/A |
| bictegravir | PR_HKU4 | Replicase polyprotein 1ab | -8.88 | -8.73 | -8.59 | N/A | N/A |
| emtricitabine | PR_HKU4 | Replicase polyprotein 1ab | -5.62 | -5.71 | -5.82 | N/A | N/A |
| tenofovir alafenamide | PR_HKU4 | Replicase polyprotein 1ab | -6.79 | -7.09 | -7.03 | N/A | N/A |
| bictegravir | PR_IBV | Replicase polyprotein 1a | -9.50 | N/A | N/A | N/A | N/A |
| emtricitabine | PR_IBV | Replicase polyprotein 1a | -5.65 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PR_IBV | Replicase polyprotein 1a | -6.80 | N/A | N/A | N/A | N/A |
| bictegravir | PR_MERs | 3C-like proteinase | -8.92 | -9.59 | N/A | N/A | N/A |
| emtricitabine | PR_MERs | 3C-like proteinase | -6.32 | -5.74 | N/A | N/A | N/A |
| tenofovir alafenamide | PR_MERs | 3C-like proteinase | -6.73 | -7.64 | N/A | N/A | N/A |
| bictegravir | PR_PEDV | 3C-like proteinase | -9.08 | N/A | N/A | N/A | N/A |
| emtricitabine | PR_PEDV | 3C-like proteinase | -5.68 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PR_PEDV | 3C-like proteinase | -7.08 | N/A | N/A | N/A | N/A |
| bictegravir | PR_SARS | Replicase polyprotein 1ab | -9.79 | -8.65 | -8.88 | 24.29% | CHEMBL2441745 |
| emtricitabine | PR_SARS | Replicase polyprotein 1ab | -5.64 | -6.58 | -5.89 | 15.25% | CHEMBL2441745 |
| tenofovir alafenamide | PR_SARS | Replicase polyprotein 1ab | -7.01 | -7.55 | -7.16 | 15.61% | CHEMBL2441741 |
| bictegravir | PR_SARS2 | 3C-like protease | -9.47 | N/A | N/A | N/A | N/A |
| emtricitabine | PR_SARS2 | 3C-like protease | -6.05 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PR_SARS2 | 3C-like protease | -6.89 | N/A | N/A | N/A | N/A |
| bictegravir | PR_TGEV | Replicase polyprotein 1a | -8.53 | N/A | N/A | N/A | N/A |
| emtricitabine | PR_TGEV | Replicase polyprotein 1a | -5.28 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | PR_TGEV | Replicase polyprotein 1a | -7.22 | N/A | N/A | N/A | N/A |
| bictegravir | RT_HIV1 | Gag-Pol polyprotein | -10.97 | -11.90 | -10.84 | 30.95% | CHEMBL4109767 |
| emtricitabine | RT_HIV1 | Gag-Pol polyprotein | -7.63 | -7.40 | -7.13 | 24.87% | CHEMBL4291913 |
| tenofovir alafenamide | RT_HIV1 | Gag-Pol polyprotein | -8.75 | -8.75 | -9.32 | 21.15% | CHEMBL4108778 |
| bictegravir | SPIKE_HCoV-229E | Spike glycoprotein | -6.23 | N/A | N/A | N/A | N/A |
| emtricitabine | SPIKE_HCoV-229E | Spike glycoprotein | -3.94 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | SPIKE_HCoV-229E | Spike glycoprotein | -5.05 | N/A | N/A | N/A | N/A |
| bictegravir | SPIKE_HCoV-NL63 | Spike glycoprotein | -7.50 | N/A | N/A | N/A | N/A |
| emtricitabine | SPIKE_HCoV-NL63 | Spike glycoprotein | -4.71 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | SPIKE_HCoV-NL63 | Spike glycoprotein | -5.47 | N/A | N/A | N/A | N/A |
| bictegravir | SPIKE_HCoV-OC43 | Spike glycoprotein | -7.77 | N/A | N/A | N/A | N/A |
| emtricitabine | SPIKE_HCoV-OC43 | Spike glycoprotein | -5.69 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | SPIKE_HCoV-OC43 | Spike glycoprotein | -6.46 | N/A | N/A | N/A | N/A |
| bictegravir | SPIKE_HKU4 | Spike glycoprotein | -8.33 | N/A | N/A | N/A | N/A |
| emtricitabine | SPIKE_HKU4 | Spike glycoprotein | -6.44 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | SPIKE_HKU4 | Spike glycoprotein | -6.33 | N/A | N/A | N/A | N/A |
| bictegravir | SPIKE_IBV | Spike glycoprotein | -7.76 | N/A | N/A | N/A | N/A |
| emtricitabine | SPIKE_IBV | Spike glycoprotein | -5.05 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | SPIKE_IBV | Spike glycoprotein | -6.17 | N/A | N/A | N/A | N/A |
| bictegravir | SPIKE_MERs | Spike glycoprotein | -8.52 | -7.63 | -7.41 | N/A | N/A |
| emtricitabine | SPIKE_MERs | Spike glycoprotein | -6.24 | -5.27 | -5.15 | N/A | N/A |
| tenofovir alafenamide | SPIKE_MERs | Spike glycoprotein | -6.80 | -6.71 | -5.60 | N/A | N/A |
| bictegravir | SPIKE_MHV | Spike glycoprotein | -8.99 | N/A | N/A | N/A | N/A |
| emtricitabine | SPIKE_MHV | Spike glycoprotein | -5.57 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | SPIKE_MHV | Spike glycoprotein | -6.83 | N/A | N/A | N/A | N/A |
| bictegravir | SPIKE_PDCoV | Spike protein | -8.13 | N/A | N/A | N/A | N/A |
| emtricitabine | SPIKE_PDCoV | Spike protein | -5.42 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | SPIKE_PDCoV | Spike protein | -6.28 | N/A | N/A | N/A | N/A |
| bictegravir | SPIKE_SARS | Spike glycoprotein | -7.85 | -7.69 | N/A | N/A | N/A |
| emtricitabine | SPIKE_SARS | Spike glycoprotein | -4.81 | -6.44 | N/A | N/A | N/A |
| tenofovir alafenamide | SPIKE_SARS | Spike glycoprotein | -6.13 | -5.86 | N/A | N/A | N/A |
| bictegravir | SPIKE_SARS2 | Spike glycoprotein | -7.23 | N/A | N/A | N/A | N/A |
| emtricitabine | SPIKE_SARS2 | Spike glycoprotein | -5.24 | N/A | N/A | N/A | N/A |
| tenofovir alafenamide | SPIKE_SARS2 | Spike glycoprotein | -5.25 | N/A | N/A | N/A | N/A |