| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -7.87 | -7.70 | -8.39 | 38.18% | CHEMBL2164330 | Inactive | 62.00% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.18 | -8.61 | -9.16 | 28.30% | CHEMBL2112766 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.71 | -8.46 | -7.80 | 28.12% | CHEMBL139438 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.08 | -8.44 | -8.41 | 16.44% | CHEMBL39 | Inactive | 68.77% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.15 | -9.16 | -8.18 | 16.44% | CHEMBL39 | Inactive | 74.86% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.86 | -9.72 | N/A | 39.62% | CHEMBL46788 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.29 | -8.81 | -9.20 | 31.58% | CHEMBL471839 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -9.23 | -10.34 | N/A | 36.21% | CHEMBL474860 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -10.40 | -10.13 | -9.94 | 16.44% | CHEMBL39 | Inactive | 90.28% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.31 | -7.06 | -7.89 | 27.69% | CHEMBL189262 | Inactive | 67.73% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.06 | -8.14 | -9.19 | 32.14% | CHEMBL556759 | Inactive | 55.99% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -8.49 | -9.24 | -8.35 | 51.22% | CHEMBL234885 | Active | 70.86% |
| AA1R_HUMAN | adenosine A1 receptor | -9.48 | -9.05 | -9.97 | 28.95% | CHEMBL3977929 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -10.34 | -10.15 | -10.46 | 28.95% | CHEMBL3977929 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -7.74 | -8.84 | -7.97 | 20.00% | CHEMBL376778 | Inactive | 84.47% |
| AA3R_HUMAN | adenosine A3 receptor | -9.91 | -9.71 | -9.42 | 27.27% | CHEMBL2312728 | Active | 51.38% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -10.15 | -4.04 | N/A | 26.92% | CHEMBL1084850 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.35 | -8.30 | -10.41 | 25.00% | CHEMBL273586 | Inactive | 62.82% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.25 | -9.30 | -10.05 | 28.95% | CHEMBL1084851 | Active | 59.04% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -10.20 | -9.95 | N/A | 24.19% | CHEMBL2377384 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -9.76 | -9.90 | -9.98 | 24.07% | CHEMBL657 | Active | 55.82% |
| ACTHR_HUMAN | melanocortin 2 receptor | -10.24 | -9.10 | -9.11 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -8.66 | -8.57 | -8.64 | 23.08% | CHEMBL648 | Inactive | 72.30% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -5.94 | -7.30 | -3.71 | 26.67% | CHEMBL61006 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -10.38 | -10.24 | -8.40 | 24.00% | CHEMBL972 | Inactive | 65.79% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -2.56 | -1.32 | -1.65 | 22.22% | CHEMBL1437 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -9.53 | -9.32 | -9.86 | 28.57% | CHEMBL1621144 | Active | 55.19% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -8.51 | -8.70 | -9.52 | 31.58% | CHEMBL4062049 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -9.93 | -10.80 | -9.68 | 27.63% | CHEMBL273028 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -9.71 | -9.62 | -9.68 | 16.81% | CHEMBL290286 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.07 | -10.20 | -9.97 | 17.65% | CHEMBL121565 | Inactive | 80.29% |
| CALCR_HUMAN | calcitonin receptor | -7.84 | -7.88 | -7.99 | 7.95% | CHEMBL2369895 | Inactive | 98.86% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.70 | -8.72 | -8.84 | 16.67% | CHEMBL1774034 | Inactive | 90.69% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -9.24 | -6.98 | -8.31 | 20.27% | CHEMBL2205805 | Inactive | 86.64% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.87 | -7.92 | -7.62 | 22.62% | CHEMBL3754334 | Inactive | 80.47% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.53 | -8.07 | -7.57 | 15.00% | CHEMBL1618631 | Inactive | 81.74% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.47 | -8.83 | -8.57 | 22.62% | CHEMBL106264 | Inactive | 96.68% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -7.56 | -8.51 | -9.17 | 14.29% | CHEMBL33329 | Inactive | 92.06% |
| CNR1_HUMAN | cannabinoid receptor 1 | -9.36 | -9.22 | -10.60 | 39.62% | CHEMBL233182 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -9.46 | -10.16 | N/A | 39.62% | CHEMBL233182 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -8.43 | N/A | N/A | 17.65% | CHEMBL191413 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.77 | -6.75 | -6.87 | 17.65% | CHEMBL191413 | Inactive | 78.10% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.95 | -8.93 | -8.86 | 27.63% | CHEMBL2181464 | Inactive | 91.52% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.61 | -6.55 | -7.79 | 22.22% | CHEMBL18442 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.01 | -8.95 | -8.75 | 26.58% | CHEMBL3325914 | Inactive | 57.58% |
| DRD2_HUMAN | dopamine receptor D2 | -8.63 | N/A | N/A | 26.09% | CHEMBL59 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.85 | N/A | N/A | 28.57% | CHEMBL484204 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -8.14 | -8.25 | N/A | 27.63% | CHEMBL184551 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -10.04 | -9.44 | -8.09 | 24.07% | CHEMBL201525 | Inactive | 51.62% |
| EDNRA_HUMAN | endothelin receptor type A | -7.23 | -7.52 | -7.41 | 20.88% | CHEMBL31662 | Inactive | 76.00% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -6.34 | -7.25 | -5.92 | 10.81% | CHEMBL2391908 | Inactive | 89.37% |
| GASR_HUMAN | cholecystokinin B receptor | -8.34 | -7.73 | -6.73 | 13.33% | CHEMBL38874 | Inactive | 90.72% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -8.08 | -9.45 | -8.77 | 19.57% | CHEMBL1269125 | Inactive | 73.90% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -5.05 | -6.79 | -4.71 | 23.86% | CHEMBL3974279 | Inactive | 61.27% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -7.13 | -8.99 | -9.02 | 20.31% | CHEMBL2112584 | Inactive | 85.73% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -6.13 | -6.39 | -6.42 | 18.10% | CHEMBL2023452 | Inactive | 97.00% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.17 | -11.70 | -11.29 | 24.00% | CHEMBL371811 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -8.33 | -8.17 | -7.46 | 18.75% | CHEMBL566136 | Inactive | 97.34% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -6.31 | -5.78 | -4.81 | 13.54% | CHEMBL432038 | Inactive | 99.96% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | -3.24 | -2.93 | -5.36 | 17.57% | CHEMBL143210 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -10.54 | N/A | N/A | 28.89% | CHEMBL47482 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.26 | -8.16 | -7.63 | 23.86% | CHEMBL2207641 | Active | 79.88% |
| HRH3_HUMAN | histamine receptor H3 | -8.22 | -8.38 | -8.35 | 50.00% | CHEMBL209478 | Active | 83.76% |
| HRH4_HUMAN | histamine receptor H4 | -8.10 | -8.56 | -7.76 | 33.96% | CHEMBL1934049 | Inactive | 65.07% |
| MC3R_HUMAN | melanocortin 3 receptor | -8.61 | -8.24 | -9.23 | 13.95% | CHEMBL460349 | Inactive | 73.48% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.34 | -7.25 | -7.22 | 29.58% | CHEMBL226023 | Inactive | 91.75% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.97 | -8.71 | -7.31 | 18.56% | CHEMBL3964883 | Inactive | 66.09% |
| MSHR_HUMAN | melanocortin 1 receptor | -8.80 | -9.26 | -8.60 | 15.38% | CHEMBL267020 | Inactive | 83.33% |
| NK1R_HUMAN | tachykinin receptor 1 | -9.24 | -9.18 | -8.86 | 37.50% | CHEMBL206490 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -9.03 | -9.10 | -9.13 | 20.00% | CHEMBL17157 | Inactive | 91.15% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.93 | -7.77 | -7.35 | 14.50% | CHEMBL1991452 | Inactive | 96.16% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.32 | -7.89 | -8.22 | 22.58% | CHEMBL573738 | Inactive | 76.51% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -8.91 | -9.37 | -8.09 | 17.82% | CHEMBL1289780 | Inactive | 68.70% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.49 | -9.43 | -8.52 | 19.67% | CHEMBL3559801 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.04 | -8.04 | -7.98 | 19.67% | CHEMBL3559801 | Inactive | 99.06% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.06 | -8.45 | -8.45 | 19.67% | CHEMBL3559801 | Inactive | 77.55% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.01 | -7.95 | -7.59 | 25.00% | CHEMBL327027 | Inactive | 94.98% |
| OPRD_HUMAN | opioid receptor delta 1 | -8.34 | -7.48 | -7.58 | 22.11% | CHEMBL3809491 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.09 | -9.38 | -8.36 | 24.49% | CHEMBL1188090 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.92 | -6.98 | -8.01 | 24.49% | CHEMBL1188090 | Inactive | 77.27% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.36 | -7.44 | -7.37 | 23.33% | CHEMBL139816 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.88 | -8.46 | -8.40 | 21.57% | CHEMBL53584 | Inactive | 80.85% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -9.91 | -9.45 | -9.20 | 37.14% | CHEMBL451372 | Inactive | 69.97% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -9.71 | -9.44 | -9.23 | 12.26% | CHEMBL3908443 | Inactive | 97.50% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -7.75 | -7.88 | -8.43 | 30.00% | CHEMBL1083095 | Inactive | 92.31% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.26 | -8.61 | -8.71 | 16.18% | CHEMBL1784685 | N/A | N/A |