| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.80 | -6.46 | -8.97 | 28.33% | CHEMBL1183249 | Inactive | 85.59% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.62 | -9.07 | -7.60 | 21.38% | CHEMBL321190 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -8.59 | -8.15 | -8.11 | 17.75% | CHEMBL501645 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.70 | -7.96 | -7.94 | 12.90% | CHEMBL103479 | Inactive | 77.04% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.22 | -10.11 | -10.50 | 14.94% | CHEMBL321967 | Inactive | 67.35% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -9.06 | -7.12 | N/A | 74.36% | CHEMBL1909065 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -9.11 | -9.94 | -8.88 | 74.36% | CHEMBL1909065 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.62 | -8.40 | N/A | 74.36% | CHEMBL1909065 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -9.37 | -8.77 | -8.14 | 20.71% | CHEMBL1632169 | Inactive | 83.43% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -7.64 | -7.98 | -8.64 | 21.79% | CHEMBL3938006 | Inactive | 71.90% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -7.73 | -7.43 | -8.47 | 74.36% | CHEMBL1909065 | Active | 96.03% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -9.22 | -8.11 | -8.10 | 30.66% | CHEMBL487192 | Inactive | 63.65% |
| AA1R_HUMAN | adenosine A1 receptor | -8.01 | -8.47 | -6.10 | 28.40% | CHEMBL3956531 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -6.46 | -6.69 | -9.11 | 24.43% | CHEMBL2113418 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -10.48 | -8.49 | -8.66 | 24.00% | CHEMBL464859 | Inactive | 80.77% |
| AA3R_HUMAN | adenosine A3 receptor | -7.44 | 0.54 | -7.40 | 48.85% | CHEMBL1200633 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -9.90 | 10.48 | N/A | 38.89% | CHEMBL353311 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.34 | -8.33 | -8.51 | 38.89% | CHEMBL353311 | Inactive | 52.05% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -10.14 | -8.37 | -8.39 | 37.37% | CHEMBL480464 | Active | 56.48% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.67 | -6.51 | N/A | 37.37% | CHEMBL480464 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -10.46 | -9.23 | -7.57 | 31.78% | CHEMBL1201027 | Active | 71.74% |
| ACTHR_HUMAN | melanocortin 2 receptor | -9.01 | -8.83 | -9.05 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -9.37 | -9.19 | -9.21 | 74.36% | CHEMBL1909065 | Active | 86.68% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -0.17 | -0.36 | 3.15 | 74.36% | CHEMBL1909065 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -9.43 | -4.90 | -2.13 | 74.36% | CHEMBL1909065 | Inactive | 99.99% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 4.41 | 5.79 | 2.62 | 74.36% | CHEMBL1909065 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -8.70 | -8.18 | -8.40 | 25.19% | CHEMBL1085395 | Inactive | 66.80% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -8.01 | -7.51 | -9.04 | 25.19% | CHEMBL1085395 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -9.80 | -7.02 | -9.06 | 25.19% | CHEMBL1085395 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -7.79 | -8.40 | -8.17 | 16.88% | CHEMBL3350599 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.64 | -8.99 | -9.07 | 20.00% | CHEMBL2372276 | Inactive | 88.43% |
| CALCR_HUMAN | calcitonin receptor | -8.43 | -8.72 | -7.84 | 16.76% | CHEMBL2369895 | Inactive | 99.02% |
| CCKAR_HUMAN | cholecystokinin A receptor | -8.71 | -8.49 | -8.85 | 19.67% | CHEMBL168182 | Inactive | 92.01% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -8.30 | -9.13 | -7.83 | 22.70% | CHEMBL344324 | Inactive | 90.79% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.12 | -8.40 | -8.02 | 29.71% | CHEMBL1681819 | Inactive | 80.51% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -8.09 | -7.09 | -7.53 | 20.19% | CHEMBL64391 | Inactive | 64.44% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.39 | -8.12 | -8.47 | 27.70% | CHEMBL278383 | Inactive | 98.49% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.00 | -8.83 | -7.93 | 19.12% | CHEMBL22776 | Inactive | 87.77% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.90 | -8.31 | -7.65 | 40.00% | CHEMBL175247 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -8.94 | -8.74 | N/A | 39.00% | CHEMBL1800732 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -6.51 | N/A | N/A | 14.17% | CHEMBL139 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.05 | -8.43 | -8.33 | 18.18% | CHEMBL3645131 | Inactive | 71.55% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.63 | -8.57 | -8.66 | 22.16% | CHEMBL3956593 | Inactive | 95.52% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.89 | -7.70 | -8.26 | 28.99% | CHEMBL1221944 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -8.39 | -10.11 | -9.16 | 19.33% | CHEMBL85409 | Inactive | 58.14% |
| DRD2_HUMAN | dopamine receptor D2 | -7.83 | N/A | N/A | 74.36% | CHEMBL1909065 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.61 | N/A | N/A | 74.36% | CHEMBL1909065 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -9.11 | -9.24 | N/A | 25.38% | CHEMBL2443008 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -7.68 | -9.31 | -5.19 | 15.87% | CHEMBL1258223 | Inactive | 93.24% |
| EDNRA_HUMAN | endothelin receptor type A | -8.38 | -8.47 | -8.26 | 29.93% | CHEMBL64424 | Inactive | 58.72% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 6.21 | 4.79 | 25.36 | 10.69% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.78 | -8.19 | -7.51 | 21.47% | CHEMBL433028 | Inactive | 84.02% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -8.06 | -6.19 | -2.36 | 32.41% | CHEMBL254372 | Inactive | 99.99% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | 1.32 | 3.38 | 0.53 | 42.55% | CHEMBL275079 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -2.42 | -2.59 | -1.90 | 42.55% | CHEMBL275079 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 6.11 | 6.55 | 6.60 | 19.05% | CHEMBL578988 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -5.31 | -0.40 | -2.95 | 27.59% | CHEMBL90501 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -4.75 | -3.03 | -4.47 | 42.55% | CHEMBL275079 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -0.25 | 4.18 | 0.52 | 22.73% | CHEMBL432038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 6.31 | 9.87 | 9.25 | 25.88% | CHEMBL280563 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -2.28 | N/A | N/A | 20.98% | CHEMBL1278112 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -8.65 | -9.23 | -9.68 | 18.90% | CHEMBL1626 | Active | 76.80% |
| HRH3_HUMAN | histamine receptor H3 | -9.01 | -10.64 | -10.17 | 25.78% | CHEMBL20338 | Active | 52.02% |
| HRH4_HUMAN | histamine receptor H4 | -8.23 | -7.98 | -8.79 | 25.78% | CHEMBL20338 | Inactive | 60.39% |
| MC3R_HUMAN | melanocortin 3 receptor | -7.56 | -8.11 | -7.34 | 20.93% | CHEMBL213956 | Inactive | 82.14% |
| MC4R_HUMAN | melanocortin 4 receptor | -8.49 | -7.44 | -7.69 | 21.62% | CHEMBL1519347 | Inactive | 97.76% |
| MC5R_HUMAN | melanocortin 5 receptor | -4.65 | -5.81 | -4.80 | 21.82% | CHEMBL1221512 | Inactive | 66.07% |
| MSHR_HUMAN | melanocortin 1 receptor | -7.44 | -7.59 | -8.41 | 20.93% | CHEMBL213752 | Inactive | 69.03% |
| NK1R_HUMAN | tachykinin receptor 1 | -9.44 | -9.09 | -7.89 | 37.23% | CHEMBL282618 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -8.38 | -8.45 | -8.50 | 32.62% | CHEMBL225264 | Inactive | 95.05% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -8.53 | -9.42 | -10.18 | 20.44% | CHEMBL1989216 | Inactive | 60.74% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.32 | -8.66 | -8.98 | 17.76% | CHEMBL1672379 | Inactive | 73.73% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -8.90 | -9.30 | -9.27 | 16.57% | CHEMBL230333 | Inactive | 71.39% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.11 | -9.05 | -9.39 | 35.29% | CHEMBL1223998 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.48 | -8.46 | -7.97 | 23.42% | CHEMBL3099726 | Inactive | 97.21% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.84 | -9.70 | -9.15 | 22.07% | CHEMBL3099723 | Inactive | 98.66% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -8.45 | -8.67 | -8.73 | 22.07% | CHEMBL3099727 | Inactive | 80.18% |
| OPRD_HUMAN | opioid receptor delta 1 | -8.06 | -7.75 | -8.17 | 35.58% | CHEMBL3597083 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -10.12 | -8.70 | -8.63 | 79.01% | CHEMBL560302 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -8.27 | -7.60 | -8.30 | 39.37% | CHEMBL3219937 | Inactive | 73.06% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.87 | -7.96 | -8.17 | 24.21% | CHEMBL3326232 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -7.55 | -7.43 | -7.73 | 98.67% | CHEMBL514432 | Active | 99.53% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -8.92 | -9.46 | -8.38 | 25.58% | CHEMBL1335190 | Inactive | 64.30% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -9.84 | -9.74 | -9.41 | 17.28% | CHEMBL3945037 | Inactive | 96.76% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -8.69 | -8.53 | -7.78 | 18.72% | CHEMBL396270 | Inactive | 85.30% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.06 | -8.49 | -8.52 | 16.75% | CHEMBL3884667 | N/A | N/A |