Spiro[4.5]decan-8-yl analogue 14 #247 Output - PAIN-CKB

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Spiro[4.5]decan-8-yl analogue 14 #247 Output Download CSV

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Gene Protein

The docking scores are in the AutoDock Vina metric.

5HT1B_HUMAN

Docking Scores:
-11.11 -11.21 -11.52
Similarity Score:
60.87%
Best Match:
CHEMBL191460

5HT2A_HUMAN

Docking Scores:
-11.44 -12.04
Similarity Score:
70.42%
Best Match:
CHEMBL234826

5HT2B_HUMAN

Docking Scores:
-10.95 -11.04 -11.11
Similarity Score:
67.05%
Best Match:
CHEMBL475245

5HT2C_HUMAN

Docking Scores:
-10.31 -12.07
Similarity Score:
60.87%
Best Match:
CHEMBL191460

AA1R_HUMAN

Docking Scores:
-10.82 -10.76 -8.68
Similarity Score:
40.30%
Best Match:
CHEMBL3765526

AA2AR_HUMAN

Docking Scores:
-10.55 -10.48 -10.74
Similarity Score:
43.55%
Best Match:
CHEMBL194704

ACES_HUMAN

Docking Scores:
-10.78 -9.97 -8.44
Similarity Score:
74.24%
Best Match:
CHEMBL56470

ACE_HUMAN

Docking Scores:
-9.74 -9.33 -8.59
Similarity Score:
47.71%
Best Match:
CHEMBL435360

ACHA9_HUMAN

Docking Scores:
-7.91
Similarity Score:
22.78%
Best Match:
CHEMBL386114

ACHB2_HUMAN

Docking Scores:
-9.56 -8.32 -6.44
Similarity Score:
N/A
Best Match:
N/A

ACM1_HUMAN

Docking Scores:
-9.92 2.30
Similarity Score:
65.48%
Best Match:
CHEMBL3600801

ACM4_HUMAN

Docking Scores:
-9.12 -8.56
Similarity Score:
55.81%
Best Match:
CHEMBL130835

ADRB2_HUMAN

Docking Scores:
-9.61 -11.84 -11.87
Similarity Score:
60.92%
Best Match:
CHEMBL1524289

AGTR2_HUMAN

Docking Scores:
-10.27 -10.60 -10.03
Similarity Score:
43.64%
Best Match:
CHEMBL376286

ALDR_HUMAN

Docking Scores:
-10.90 -10.42 -10.35
Similarity Score:
37.88%
Best Match:
CHEMBL4071420

AMPN_HUMAN

Docking Scores:
-10.00 -10.23 -9.23
Similarity Score:
39.00%
Best Match:
CHEMBL2204959

AOFA_HUMAN

Docking Scores:
-11.84 -11.65 -11.01
Similarity Score:
46.94%
Best Match:
CHEMBL3781494

AOFB_HUMAN

Docking Scores:
-10.69 -9.70 -10.85
Similarity Score:
49.07%
Best Match:
CHEMBL1814072

BACE1_HUMAN

Docking Scores:
-8.46 -9.32 -9.08
Similarity Score:
57.61%
Best Match:
CHEMBL3354252

CAH2_HUMAN

Docking Scores:
-9.03 -8.90 -9.10
Similarity Score:
54.79%
Best Match:
CHEMBL3092749

CASP1_HUMAN

Docking Scores:
-7.75 -7.73 -7.12
Similarity Score:
50.50%
Best Match:
CHEMBL590028

CDK5_HUMAN

Docking Scores:
-9.23 -9.41 -10.77
Similarity Score:
51.65%
Best Match:
CHEMBL1990254

CHLE_HUMAN

Docking Scores:
-9.66 -9.42 -9.89
Similarity Score:
62.50%
Best Match:
CHEMBL4077386

CNR1_HUMAN

Docking Scores:
-9.69 -10.78 -11.54
Similarity Score:
61.70%
Best Match:
CHEMBL3397448

CNR2_HUMAN

Docking Scores:
-12.44 -11.22
Similarity Score:
66.67%
Best Match:
CHEMBL579193

COLI_HUMAN

Docking Scores:
-9.75 -9.65 -9.83
Similarity Score:
N/A
Best Match:
N/A

COMT_HUMAN

Docking Scores:
-8.06 -7.55 -7.67
Similarity Score:
33.33%
Best Match:
CHEMBL3818719

CRP_HUMAN

Docking Scores:
-6.51 -6.17
Similarity Score:
N/A
Best Match:
N/A

CXCR1_HUMAN

Docking Scores:
-1.91
Similarity Score:
26.78%
Best Match:
CHEMBL556862

CXCR4_HUMAN

Docking Scores:
-10.00 -8.00 -8.85
Similarity Score:
59.15%
Best Match:
CHEMBL2170299

DRD2_HUMAN

Docking Scores:
-10.82
Similarity Score:
70.51%
Best Match:
CHEMBL185156

DRD3_HUMAN

Docking Scores:
-10.61
Similarity Score:
92.54%
Best Match:
CHEMBL485227

DRD4_HUMAN

Docking Scores:
-10.46 -10.23
Similarity Score:
92.54%
Best Match:
CHEMBL485227

EDN1_HUMAN

Docking Scores:
-10.59
Similarity Score:
N/A
Best Match:
N/A

ESR1_HUMAN

Docking Scores:
-9.74 -9.39 -9.49
Similarity Score:
56.00%
Best Match:
CHEMBL244001

FABP5_HUMAN

Docking Scores:
-7.56 -6.82 -7.14
Similarity Score:
30.87%
Best Match:
CHEMBL3941588

FYN_HUMAN

Docking Scores:
-9.09
Similarity Score:
54.32%
Best Match:
CHEMBL1968394

GLRA3_HUMAN

Docking Scores:
-11.51 -10.66 -10.88
Similarity Score:
15.05%
Best Match:
CHEMBL4074873

GLRA3_HUMAN

Docking Scores:
-10.61
Similarity Score:
15.05%
Best Match:
CHEMBL4074873

GRM5_HUMAN

Docking Scores:
-9.02 -7.86 -8.11
Similarity Score:
66.67%
Best Match:
CHEMBL539185

HPGDS_HUMAN

Docking Scores:
-9.70 -9.64 -9.88
Similarity Score:
50.00%
Best Match:
CHEMBL2035650

HRH1_HUMAN

Docking Scores:
-6.99
Similarity Score:
55.17%
Best Match:
CHEMBL1882801

HYES_HUMAN

Docking Scores:
-9.92 -9.48 -9.37
Similarity Score:
75.34%
Best Match:
CHEMBL1507203

IKKB_HUMAN

Docking Scores:
-9.72
Similarity Score:
41.18%
Best Match:
CHEMBL1761511

MDR1_HUMAN

Docking Scores:
-9.62 -10.55
Similarity Score:
58.90%
Best Match:
CHEMBL2398097

MIF_HUMAN

Docking Scores:
-9.55 -10.02 -8.53
Similarity Score:
40.18%
Best Match:
CHEMBL1604170

MK01_HUMAN

Docking Scores:
-8.81 -8.59 -10.09
Similarity Score:
56.96%
Best Match:
CHEMBL1977135

MK03_HUMAN

Docking Scores:
-9.48 -9.05 -9.56
Similarity Score:
48.70%
Best Match:
CHEMBL3798926

MTOR_HUMAN

Docking Scores:
-11.39 -11.85 -11.40
Similarity Score:
43.28%
Best Match:
CHEMBL1795875

NEP_HUMAN

Docking Scores:
-8.48 -8.14 -9.04
Similarity Score:
55.29%
Best Match:
CHEMBL378050

NK1R_HUMAN

Docking Scores:
-9.39 -9.52 -9.78
Similarity Score:
58.88%
Best Match:
CHEMBL305375

NMDE1_HUMAN

Docking Scores:
-9.32 -8.69 -10.70
Similarity Score:
30.77%
Best Match:
CHEMBL284237

NMDE2_HUMAN

Docking Scores:
-11.39 -10.29 -10.81
Similarity Score:
45.24%
Best Match:
CHEMBL3357785

NMDZ1_HUMAN

Docking Scores:
-9.29 -9.91 -10.70
Similarity Score:
32.14%
Best Match:
CHEMBL354003

NOS1_HUMAN

Docking Scores:
-10.90 -11.02 -10.31
Similarity Score:
42.86%
Best Match:
CHEMBL258348

NOS2_HUMAN

Docking Scores:
-10.30 -9.84 -3.46
Similarity Score:
42.86%
Best Match:
CHEMBL258348

NTRK1_HUMAN

Docking Scores:
-10.70 -10.64 -10.77
Similarity Score:
53.49%
Best Match:
CHEMBL1976290

OPRD_HUMAN

Docking Scores:
-8.63 -7.45 -9.05
Similarity Score:
65.43%
Best Match:
CHEMBL27579

OPRK_HUMAN

Docking Scores:
-10.98 -11.08 -9.67
Similarity Score:
63.86%
Best Match:
CHEMBL340724

OPRM_MOUSE

Docking Scores:
-9.59 -9.68
Similarity Score:
61.63%
Best Match:
CHEMBL2051964

OPRX_HUMAN

Docking Scores:
-8.96 -8.85 -9.25
Similarity Score:
60.76%
Best Match:
CHEMBL3969636

P2RX3_HUMAN

Docking Scores:
-6.88 -6.96 -7.48
Similarity Score:
41.10%
Best Match:
CHEMBL3669697

P2Y12_HUMAN

Docking Scores:
-9.23 -10.04 -10.51
Similarity Score:
48.28%
Best Match:
CHEMBL599606

PAR1_HUMAN

Docking Scores:
-11.53
Similarity Score:
46.30%
Best Match:
CHEMBL3658415

PDE4B_HUMAN

Docking Scores:
-9.97 -10.36 -10.34
Similarity Score:
41.03%
Best Match:
CHEMBL288928

PDE5A_HUMAN

Docking Scores:
-10.16 -10.23 -10.14
Similarity Score:
43.80%
Best Match:
CHEMBL190423

PERM_HUMAN

Docking Scores:
-9.03 -9.05 -8.81
Similarity Score:
42.17%
Best Match:
CHEMBL3892909

PGH1_SHEEP

Docking Scores:
-7.81 -9.30 -9.00
Similarity Score:
50.00%
Best Match:
CHEMBL268643

PGH2_HUMAN

Docking Scores:
-4.10 -7.46 -7.41
Similarity Score:
47.27%
Best Match:
CHEMBL148931

PPAP_HUMAN

Docking Scores:
-9.17
Similarity Score:
27.84%
Best Match:
CHEMBL498632

PPARG_HUMAN

Docking Scores:
-9.56 -10.44 -9.22
Similarity Score:
52.50%
Best Match:
CHEMBL3695819

PRGR_HUMAN

Docking Scores:
-4.65 -2.33 -8.07
Similarity Score:
45.22%
Best Match:
CHEMBL144345

PTGES_HUMAN

Docking Scores:
-7.48
Similarity Score:
51.30%
Best Match:
CHEMBL3092283

SC6A4_HUMAN

Docking Scores:
-11.22 -10.94 -10.66
Similarity Score:
71.60%
Best Match:
CHEMBL3612829

SCN9A_HUMAN

Docking Scores:
-9.85
Similarity Score:
56.98%
Best Match:
CHEMBL2152694

TLR4_HUMAN

Docking Scores:
-10.77 -10.85 -10.52
Similarity Score:
28.16%
Best Match:
CHEMBL4068003

TNFA_HUMAN

Docking Scores:
-8.24
Similarity Score:
41.18%
Best Match:
CHEMBL11440

TRBM_HUMAN

Docking Scores:
-9.45 -7.40
Similarity Score:
N/A
Best Match:
N/A

TRPM4_HUMAN

Docking Scores:
-7.30 -7.68
Similarity Score:
N/A
Best Match:
N/A

TRPM8_FICAL

Docking Scores:
-10.55
Similarity Score:
N/A
Best Match:
N/A

TRPV1_RAT

Docking Scores:
-10.42
Similarity Score:
51.69%
Best Match:
CHEMBL86708

TRPV2_RABIT

Docking Scores:
-9.21 -9.20
Similarity Score:
N/A
Best Match:
N/A

TRPV3_HUMAN

Docking Scores:
-9.24 -7.51
Similarity Score:
40.62%
Best Match:
CHEMBL3639953

TRXR1_HUMAN

Docking Scores:
-9.75 -8.41 -7.70
Similarity Score:
N/A
Best Match:
N/A

TRY1_HUMAN

Docking Scores:
-7.68
Similarity Score:
54.78%
Best Match:
CHEMBL45106