| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -8.16 | -7.81 | -8.69 | 51.18% | CHEMBL29951 | Active | 60.04% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -9.19 | -9.16 | -8.17 | 51.18% | CHEMBL29951 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -9.18 | -8.69 | -8.20 | 51.18% | CHEMBL29951 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -8.65 | -8.38 | -8.25 | 24.59% | CHEMBL22744 | Inactive | 73.52% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -8.99 | -9.21 | -9.07 | 25.58% | CHEMBL3616488 | Inactive | 73.43% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.60 | -9.36 | N/A | 49.54% | CHEMBL268890 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -9.25 | -9.09 | -9.58 | 45.45% | CHEMBL2022186 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.80 | -8.49 | N/A | 48.18% | CHEMBL2022189 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -9.82 | -9.35 | -8.85 | 35.56% | CHEMBL571799 | Inactive | 57.63% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -8.60 | -7.30 | -8.01 | 40.48% | CHEMBL278751 | Inactive | 66.83% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -8.33 | -7.82 | -9.05 | 43.83% | CHEMBL429023 | Active | 66.96% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -9.01 | -8.73 | -8.45 | 42.07% | CHEMBL2158029 | Active | 58.86% |
| AA1R_HUMAN | adenosine A1 receptor | -8.91 | -8.76 | -8.50 | 27.66% | CHEMBL1544 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -8.35 | -8.66 | -9.07 | 27.21% | CHEMBL355390 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -8.28 | -8.39 | -9.04 | 27.13% | CHEMBL3317575 | Inactive | 56.72% |
| AA3R_HUMAN | adenosine A3 receptor | -9.35 | -6.37 | -9.16 | 47.62% | CHEMBL513389 | Active | 57.66% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.90 | -2.48 | N/A | 44.09% | CHEMBL343236 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -9.51 | -8.72 | -10.52 | 44.09% | CHEMBL343236 | Active | 56.80% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -8.44 | -9.97 | -9.23 | 41.60% | CHEMBL3085495 | Active | 50.42% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.01 | -8.51 | N/A | 41.60% | CHEMBL3085495 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -10.18 | -10.30 | -8.43 | 35.66% | CHEMBL490 | Active | 74.21% |
| ACTHR_HUMAN | melanocortin 2 receptor | -10.67 | -10.30 | -9.77 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -9.15 | -8.07 | -8.64 | 45.97% | CHEMBL101739 | Active | 58.88% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -7.69 | -8.78 | -4.39 | 47.62% | CHEMBL513389 | Inactive | 50.24% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -8.68 | -9.24 | -8.67 | 42.54% | CHEMBL179648 | Active | 69.59% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | -1.80 | -1.14 | -0.22 | 42.54% | CHEMBL179648 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -8.95 | -9.08 | -9.05 | 45.24% | CHEMBL26917 | Active | 75.48% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -8.00 | -9.88 | -9.58 | 47.62% | CHEMBL513389 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -9.06 | -8.51 | -9.06 | 43.07% | CHEMBL1201237 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -8.65 | -8.44 | -8.55 | 35.48% | CHEMBL154057 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -9.18 | -8.94 | -8.85 | 21.68% | CHEMBL553530 | Inactive | 88.31% |
| CALCR_HUMAN | calcitonin receptor | -7.85 | -8.62 | -8.12 | 18.18% | CHEMBL2369897 | Inactive | 98.85% |
| CCKAR_HUMAN | cholecystokinin A receptor | -9.25 | -8.36 | -8.68 | 25.00% | CHEMBL250974 | Inactive | 80.28% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -7.95 | -8.20 | -9.04 | 35.29% | CHEMBL2391795 | Inactive | 82.83% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -8.04 | -8.50 | -7.96 | 47.01% | CHEMBL3754764 | Inactive | 52.26% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -7.81 | -7.30 | -7.88 | 32.21% | CHEMBL1907216 | Inactive | 62.01% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -8.22 | -8.55 | -8.27 | 32.96% | CHEMBL2281967 | Inactive | 90.81% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -8.51 | -9.10 | -10.00 | 40.79% | CHEMBL1213917 | Inactive | 75.86% |
| CNR1_HUMAN | cannabinoid receptor 1 | -7.64 | -8.62 | -9.60 | 100.00% | CHEMBL600602 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -10.09 | -9.84 | N/A | 100.00% | CHEMBL111148 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.81 | N/A | N/A | 25.00% | CHEMBL220182 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -8.03 | -7.34 | -7.18 | 40.14% | CHEMBL3645131 | Inactive | 54.90% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -8.70 | -8.90 | -9.19 | 37.65% | CHEMBL3697086 | Inactive | 82.72% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -8.56 | -7.88 | -7.20 | 31.34% | CHEMBL126657 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -8.72 | -8.79 | -9.02 | 46.53% | CHEMBL3966718 | Active | 70.56% |
| DRD2_HUMAN | dopamine receptor D2 | -8.11 | N/A | N/A | 48.44% | CHEMBL64553 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -8.65 | N/A | N/A | 100.00% | CHEMBL465 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -8.31 | -8.39 | N/A | 48.44% | CHEMBL64553 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -9.58 | -8.81 | -8.41 | 42.38% | CHEMBL217299 | Active | 79.38% |
| EDNRA_HUMAN | endothelin receptor type A | -7.56 | -7.68 | -8.06 | 43.15% | CHEMBL431651 | Inactive | 56.58% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | -3.01 | -2.53 | 4.66 | 21.95% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -8.10 | -7.85 | -6.86 | 39.67% | CHEMBL452991 | Inactive | 73.96% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -9.61 | -9.84 | -9.14 | 39.17% | CHEMBL254372 | Active | 59.68% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | -5.22 | -4.25 | -4.56 | 45.04% | CHEMBL186584 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -5.33 | -6.71 | -5.28 | 39.84% | CHEMBL341457 | Inactive | 53.02% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | -0.68 | -0.93 | -0.72 | 30.92% | CHEMBL2063423 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -9.35 | -5.75 | -5.53 | 44.35% | CHEMBL1682820 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -8.89 | -9.09 | -8.77 | 15.62% | CHEMBL2381641 | Inactive | 97.95% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | -3.01 | -1.51 | -2.80 | 36.76% | CHEMBL432038 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 0.65 | 0.75 | 2.39 | 36.76% | CHEMBL432038 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -4.63 | N/A | N/A | 41.60% | CHEMBL1101 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -9.14 | -8.77 | -8.68 | 38.57% | CHEMBL490632 | Active | 98.54% |
| HRH3_HUMAN | histamine receptor H3 | -7.80 | -9.27 | -9.03 | 52.07% | CHEMBL2013048 | Active | 69.42% |
| HRH4_HUMAN | histamine receptor H4 | -9.19 | -9.12 | -9.44 | 41.86% | CHEMBL1934062 | Active | 55.35% |
| MC3R_HUMAN | melanocortin 3 receptor | -9.09 | -8.09 | -7.60 | 25.67% | CHEMBL192450 | Inactive | 69.87% |
| MC4R_HUMAN | melanocortin 4 receptor | -7.46 | -7.47 | -7.63 | 36.17% | CHEMBL578944 | Inactive | 83.33% |
| MC5R_HUMAN | melanocortin 5 receptor | -6.42 | -7.80 | -5.42 | 26.06% | CHEMBL3913861 | Inactive | 87.13% |
| MSHR_HUMAN | melanocortin 1 receptor | -8.65 | -8.61 | -8.40 | 28.29% | CHEMBL442537 | Inactive | 77.20% |
| NK1R_HUMAN | tachykinin receptor 1 | -8.17 | -8.51 | -7.78 | 40.91% | CHEMBL2112368 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -8.54 | -8.17 | -8.22 | 33.08% | CHEMBL221753 | Inactive | 95.98% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -7.82 | -7.13 | -7.76 | 25.89% | CHEMBL2001553 | Inactive | 92.34% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -8.22 | -8.04 | -7.78 | 23.43% | CHEMBL2208334 | Inactive | 72.01% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -8.99 | -9.76 | -8.54 | 30.73% | CHEMBL1801359 | Inactive | 58.33% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -9.24 | -8.84 | -8.78 | 40.19% | CHEMBL3559801 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -8.26 | -8.11 | -7.95 | 40.19% | CHEMBL3559801 | Inactive | 94.45% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -8.54 | -8.73 | -8.14 | 40.19% | CHEMBL3559801 | Inactive | 83.66% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -7.96 | -7.85 | -8.01 | 61.54% | CHEMBL469257 | Active | 93.46% |
| OPRD_HUMAN | opioid receptor delta 1 | -8.84 | -7.10 | -7.43 | 49.11% | CHEMBL410907 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -9.48 | -8.81 | -8.28 | 49.11% | CHEMBL410907 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -9.41 | -6.94 | -8.54 | 49.11% | CHEMBL410907 | Inactive | 61.36% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.21 | -8.33 | -9.02 | 44.27% | CHEMBL3262362 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -8.31 | -9.23 | -8.49 | 43.80% | CHEMBL297624 | Active | 59.37% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -9.40 | -9.37 | -9.65 | 38.12% | CHEMBL1732597 | Inactive | 67.15% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -10.18 | -10.03 | -10.32 | 23.35% | CHEMBL3897841 | Inactive | 81.87% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -8.45 | -7.71 | -9.06 | 33.72% | CHEMBL430676 | Inactive | 89.28% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -8.74 | -8.97 | -8.47 | 18.06% | CHEMBL483749 | N/A | N/A |