| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||||
| Diclophenac | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.19 | -8.46 | -8.22 | 30.37% | CHEMBL71091 |
| Morphine | 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -8.23 | -9.04 | -8.28 | 52.63% | CHEMBL29951 |
| Diclophenac | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.06 | -8.28 | N/A | 46.53% | CHEMBL415 |
| Morphine | 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -8.82 | -7.97 | N/A | 51.96% | CHEMBL3695438 |
| Diclophenac | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.22 | -8.68 | -8.66 | 46.53% | CHEMBL415 |
| Morphine | 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -8.43 | -8.69 | -8.74 | 51.06% | CHEMBL445106 |
| Diclophenac | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.44 | -8.58 | N/A | 46.53% | CHEMBL415 |
| Morphine | 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -8.41 | -9.00 | N/A | 51.06% | CHEMBL445106 |
| Diclophenac | AA1R_HUMAN | adenosine A1 receptor | -7.29 | -7.36 | -7.74 | 29.75% | CHEMBL2260644 |
| Morphine | AA1R_HUMAN | adenosine A1 receptor | -7.66 | -8.26 | -4.65 | 29.96% | CHEMBL3317575 |
| Diclophenac | AA2AR_HUMAN | adenosine A2a receptor | -7.76 | -7.71 | -8.16 | 34.91% | CHEMBL603094 |
| Morphine | AA2AR_HUMAN | adenosine A2a receptor | -8.62 | -9.48 | -10.40 | 34.24% | CHEMBL559023 |
| Diclophenac | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -8.71 | -8.16 | -9.38 | 35.43% | CHEMBL1085858 |
| Morphine | ACES_HUMAN | acetylcholinesterase (Cartwright blood group) | -9.76 | -8.85 | -8.78 | 66.01% | CHEMBL569978 |
| Diclophenac | ACE_HUMAN | angiotensin I converting enzyme | -7.45 | -7.41 | -7.29 | 29.63% | CHEMBL23849 |
| Morphine | ACE_HUMAN | angiotensin I converting enzyme | -8.53 | -8.74 | -7.71 | 37.12% | CHEMBL1165 |
| Diclophenac | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -7.09 | N/A | N/A | 17.01% | CHEMBL386114 |
| Morphine | ACHA9_HUMAN | cholinergic receptor nicotinic alpha 9 subunit | -7.08 | N/A | N/A | 21.72% | CHEMBL386114 |
| Diclophenac | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -6.54 | -8.23 | -6.56 | N/A | N/A |
| Morphine | ACHB2_HUMAN | cholinergic receptor nicotinic beta 2 subunit | -5.44 | -3.29 | -5.96 | N/A | N/A |
| Diclophenac | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -8.76 | -4.91 | N/A | 46.53% | CHEMBL415 |
| Morphine | ACM1_HUMAN | cholinergic receptor muscarinic 1 | -10.02 | 3.46 | N/A | 45.66% | CHEMBL343236 |
| Diclophenac | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -8.67 | -7.51 | N/A | 46.53% | CHEMBL415 |
| Morphine | ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.37 | -6.22 | N/A | 39.27% | CHEMBL1346 |
| Diclophenac | ADRB2_HUMAN | adrenoceptor beta 2 | -7.35 | -8.61 | -8.50 | 44.95% | CHEMBL154419 |
| Morphine | ADRB2_HUMAN | adrenoceptor beta 2 | -7.41 | -7.50 | -8.85 | 43.26% | CHEMBL513389 |
| Diclophenac | AGTR2_HUMAN | angiotensin II receptor type 2 | -7.57 | -7.50 | -7.34 | 25.67% | CHEMBL40381 |
| Morphine | AGTR2_HUMAN | angiotensin II receptor type 2 | -8.15 | -7.81 | -7.80 | 42.67% | CHEMBL154057 |
| Diclophenac | ALDR_HUMAN | aldo-keto reductase family 1 member B | -7.93 | -7.61 | -7.76 | 35.23% | CHEMBL77283 |
| Morphine | ALDR_HUMAN | aldo-keto reductase family 1 member B | -7.87 | -6.59 | -7.12 | 32.54% | CHEMBL311679 |
| Diclophenac | AMPN_HUMAN | alanyl aminopeptidase, membrane | -7.15 | -8.06 | -7.99 | 29.69% | CHEMBL3764432 |
| Morphine | AMPN_HUMAN | alanyl aminopeptidase, membrane | -8.15 | -8.23 | -8.00 | 33.78% | CHEMBL1782887 |
| Diclophenac | AOFA_HUMAN | monoamine oxidase A | -8.04 | -8.37 | -8.67 | 35.65% | CHEMBL1642672 |
| Morphine | AOFA_HUMAN | monoamine oxidase A | -8.66 | -9.39 | -8.25 | 34.30% | CHEMBL4073457 |
| Diclophenac | AOFB_HUMAN | monoamine oxidase B | -8.49 | -8.36 | -8.88 | 36.44% | CHEMBL3319243 |
| Morphine | AOFB_HUMAN | monoamine oxidase B | -9.87 | -8.60 | -9.19 | 35.75% | CHEMBL4113794 |
| Diclophenac | BACE1_HUMAN | beta-secretase 1 | -6.69 | -6.82 | -7.46 | 33.06% | CHEMBL3627961 |
| Morphine | BACE1_HUMAN | beta-secretase 1 | -6.94 | -7.39 | -8.50 | 43.53% | CHEMBL3955763 |
| Diclophenac | CAH2_HUMAN | carbonic anhydrase 2 | -7.31 | -7.42 | -7.15 | 44.58% | CHEMBL23832 |
| Morphine | CAH2_HUMAN | carbonic anhydrase 2 | -7.53 | -7.29 | -6.77 | 40.44% | CHEMBL3786651 |
| Diclophenac | CASP1_HUMAN | caspase 1 | -5.75 | -6.77 | -5.58 | 32.35% | CHEMBL78154 |
| Morphine | CASP1_HUMAN | caspase 1 | -6.89 | -7.24 | -6.96 | 34.62% | CHEMBL3898379 |
| Diclophenac | CDK5_HUMAN | cyclin dependent kinase 5 | -7.33 | -7.84 | -8.35 | 46.43% | CHEMBL1991734 |
| Morphine | CDK5_HUMAN | cyclin dependent kinase 5 | -6.44 | -6.87 | -5.18 | 29.55% | CHEMBL422897 |
| Diclophenac | CHLE_HUMAN | butyrylcholinesterase | -8.65 | -8.20 | -8.70 | 45.59% | CHEMBL3087676 |
| Morphine | CHLE_HUMAN | butyrylcholinesterase | -9.46 | -9.69 | -9.90 | 43.52% | CHEMBL366411 |
| Diclophenac | CNR1_HUMAN | cannabinoid receptor 1 | -7.80 | -8.14 | -8.82 | 46.55% | CHEMBL3936647 |
| Morphine | CNR1_HUMAN | cannabinoid receptor 1 | -8.92 | -8.18 | -8.41 | 56.82% | CHEMBL303479 |
| Diclophenac | CNR2_HUMAN | cannabinoid receptor 2 | -8.58 | -8.70 | N/A | 38.18% | CHEMBL2326302 |
| Morphine | CNR2_HUMAN | cannabinoid receptor 2 | -9.73 | -9.02 | N/A | 56.82% | CHEMBL303479 |
| Diclophenac | COLI_HUMAN | proopiomelanocortin | -7.40 | -7.19 | -7.23 | N/A | N/A |
| Morphine | COLI_HUMAN | proopiomelanocortin | -8.00 | -8.20 | -6.57 | N/A | N/A |
| Diclophenac | COMT_HUMAN | catechol-O-methyltransferase | -6.26 | -6.12 | -6.36 | 22.76% | CHEMBL1324 |
| Morphine | COMT_HUMAN | catechol-O-methyltransferase | -6.29 | -6.70 | -5.75 | 22.70% | CHEMBL3819488 |
| Diclophenac | CRP_HUMAN | C-reactive protein | -5.84 | -5.77 | N/A | N/A | N/A |
| Morphine | CRP_HUMAN | C-reactive protein | -6.20 | -6.58 | N/A | N/A | N/A |
| Diclophenac | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -7.66 | N/A | N/A | 100.00% | CHEMBL139 |
| Morphine | CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -9.03 | N/A | N/A | 28.19% | CHEMBL490688 |
| Diclophenac | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.70 | -6.68 | -7.09 | 28.18% | CHEMBL3908835 |
| Morphine | CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -7.80 | -6.47 | -7.22 | 33.92% | CHEMBL2029611 |
| Diclophenac | DRD2_HUMAN | dopamine receptor D2 | -7.22 | N/A | N/A | 46.53% | CHEMBL415 |
| Morphine | DRD2_HUMAN | dopamine receptor D2 | -7.56 | N/A | N/A | 55.49% | CHEMBL170976 |
| Diclophenac | DRD3_HUMAN | dopamine receptor D3 | -7.96 | N/A | N/A | 46.53% | CHEMBL415 |
| Morphine | DRD3_HUMAN | dopamine receptor D3 | -8.83 | N/A | N/A | 55.49% | CHEMBL170976 |
| Diclophenac | DRD4_HUMAN | dopamine receptor D4 | -8.10 | -8.17 | N/A | 38.84% | CHEMBL322326 |
| Morphine | DRD4_HUMAN | dopamine receptor D4 | -7.98 | -8.26 | N/A | 47.67% | CHEMBL132261 |
| Diclophenac | EDN1_HUMAN | endothelin 1 | -6.83 | N/A | N/A | N/A | N/A |
| Morphine | EDN1_HUMAN | endothelin 1 | -7.23 | N/A | N/A | N/A | N/A |
| Diclophenac | ESR1_HUMAN | estrogen receptor 1 | -7.95 | -7.67 | -7.73 | 36.63% | CHEMBL3234617 |
| Morphine | ESR1_HUMAN | estrogen receptor 1 | -9.00 | -8.76 | -8.75 | 44.56% | CHEMBL178559 |
| Diclophenac | FABP5_HUMAN | fatty acid binding protein 5 | -7.55 | -5.19 | -5.40 | 34.48% | CHEMBL212860 |
| Morphine | FABP5_HUMAN | fatty acid binding protein 5 | -8.76 | -6.97 | -6.27 | 30.54% | CHEMBL437489 |
| Diclophenac | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -7.93 | N/A | N/A | 46.43% | CHEMBL1991734 |
| Morphine | FYN_HUMAN | FYN proto-oncogene, Src family tyrosine kinase | -7.44 | N/A | N/A | 28.72% | CHEMBL221753 |
| Diclophenac | GLRA3_HUMAN | glycine receptor alpha 3 | -8.85 | -8.83 | -8.93 | 13.55% | CHEMBL4074873 |
| Diclophenac | GLRA3_HUMAN | glycine receptor alpha 3 | -8.66 | N/A | N/A | 13.55% | CHEMBL4074873 |
| Morphine | GLRA3_HUMAN | glycine receptor alpha 3 | -8.35 | -8.10 | -7.91 | 24.31% | CHEMBL4070615 |
| Morphine | GLRA3_HUMAN | glycine receptor alpha 3 | -9.51 | N/A | N/A | 24.31% | CHEMBL4070615 |
| Diclophenac | GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.67 | -7.54 | -6.82 | 37.01% | CHEMBL239594 |
| Morphine | GRM5_HUMAN | glutamate metabotropic receptor 5 | -7.11 | -4.70 | -4.34 | 33.15% | CHEMBL1289626 |
| Diclophenac | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.28 | -6.68 | -7.62 | 30.18% | CHEMBL572528 |
| Morphine | HPGDS_HUMAN | hematopoietic prostaglandin D synthase | -7.22 | -6.78 | -6.30 | 23.72% | CHEMBL3698265 |
| Diclophenac | HRH1_HUMAN | histamine receptor H1 | -8.69 | N/A | N/A | 47.06% | CHEMBL2158825 |
| Morphine | HRH1_HUMAN | histamine receptor H1 | -4.08 | N/A | N/A | 45.25% | CHEMBL476839 |
| Diclophenac | HYES_HUMAN | epoxide hydrolase 2 | -8.00 | -8.24 | -6.89 | 37.61% | CHEMBL478147 |
| Morphine | HYES_HUMAN | epoxide hydrolase 2 | -8.21 | -8.04 | -8.05 | 42.70% | CHEMBL1672128 |
| Diclophenac | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -7.95 | N/A | N/A | 29.66% | CHEMBL3823257 |
| Morphine | IKKB_HUMAN | inhibitor of nuclear factor kappa B kinase subunit beta | -6.24 | N/A | N/A | 31.51% | CHEMBL1672879 |
| Diclophenac | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -7.33 | -7.51 | N/A | 41.05% | CHEMBL72 |
| Morphine | MDR1_HUMAN | ATP binding cassette subfamily B member 1 | -8.46 | -7.36 | N/A | 100.00% | CHEMBL70 |
| Diclophenac | MIF_HUMAN | macrophage migration inhibitory factor | -6.09 | -6.49 | -5.81 | 25.89% | CHEMBL223319 |
| Morphine | MIF_HUMAN | macrophage migration inhibitory factor | -5.90 | -6.55 | -6.62 | 30.43% | CHEMBL2375651 |
| Diclophenac | MK01_HUMAN | mitogen-activated protein kinase 1 | -7.07 | -7.62 | -7.94 | 33.06% | CHEMBL2003341 |
| Morphine | MK01_HUMAN | mitogen-activated protein kinase 1 | -6.98 | -7.80 | -7.41 | 39.53% | CHEMBL555017 |
| Diclophenac | MK03_HUMAN | mitogen-activated protein kinase 3 | -7.75 | -7.65 | -7.67 | 25.49% | CHEMBL3798624 |
| Morphine | MK03_HUMAN | mitogen-activated protein kinase 3 | -6.44 | -6.79 | -7.50 | 39.53% | CHEMBL555017 |
| Diclophenac | MTOR_HUMAN | mechanistic target of rapamycin kinase | -7.87 | -8.29 | -8.13 | 37.76% | CHEMBL2348411 |
| Morphine | MTOR_HUMAN | mechanistic target of rapamycin kinase | -8.52 | -8.62 | -8.41 | 33.33% | CHEMBL4074753 |
| Diclophenac | NEP_HUMAN | membrane metalloendopeptidase | -7.82 | -6.90 | -7.67 | 28.21% | CHEMBL225085 |
| Morphine | NEP_HUMAN | membrane metalloendopeptidase | -8.18 | -8.44 | -7.97 | 38.24% | CHEMBL2062138 |
| Diclophenac | NK1R_HUMAN | tachykinin receptor 1 | -7.55 | -8.35 | -7.84 | 34.69% | CHEMBL92032 |
| Morphine | NK1R_HUMAN | tachykinin receptor 1 | -8.75 | -7.09 | -7.95 | 45.41% | CHEMBL2114439 |
| Diclophenac | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -8.50 | -8.80 | -8.42 | 15.54% | CHEMBL2333945 |
| Morphine | NMDE1_HUMAN | glutamate ionotropic receptor NMDA type subunit 2A | -7.65 | -7.73 | -7.52 | 25.65% | CHEMBL284237 |
| Diclophenac | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -8.62 | -8.19 | -9.62 | 25.53% | CHEMBL161977 |
| Morphine | NMDE2_HUMAN | glutamate ionotropic receptor NMDA type subunit 2B | -7.48 | -9.52 | -6.65 | 39.44% | CHEMBL3357783 |
| Diclophenac | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -8.66 | -8.55 | -8.42 | 28.82% | CHEMBL401253 |
| Morphine | NMDZ1_HUMAN | glutamate ionotropic receptor NMDA type subunit 1 | -7.65 | -7.70 | -7.52 | 20.81% | CHEMBL419399 |
| Diclophenac | NOS1_HUMAN | nitric oxide synthase 1 | -8.26 | -8.29 | -8.68 | 34.82% | CHEMBL49881 |
| Morphine | NOS1_HUMAN | nitric oxide synthase 1 | -8.04 | -7.57 | -8.70 | 34.50% | CHEMBL42968 |
| Diclophenac | NOS2_HUMAN | nitric oxide synthase 2 | -7.09 | -7.50 | -8.02 | 34.82% | CHEMBL49881 |
| Morphine | NOS2_HUMAN | nitric oxide synthase 2 | -6.89 | -8.84 | -7.90 | 34.50% | CHEMBL42968 |
| Diclophenac | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -8.08 | -8.11 | -8.12 | 46.43% | CHEMBL1991734 |
| Morphine | NTRK1_HUMAN | neurotrophic receptor tyrosine kinase 1 | -7.40 | -8.00 | -7.70 | 39.31% | CHEMBL444109 |
| Diclophenac | OPRD_HUMAN | opioid receptor delta 1 | -7.03 | -6.28 | -7.00 | 39.26% | CHEMBL1642757 |
| Morphine | OPRD_HUMAN | opioid receptor delta 1 | -7.14 | -6.79 | -7.36 | 100.00% | CHEMBL70 |
| Diclophenac | OPRK_HUMAN | opioid receptor kappa 1 | -8.51 | -8.39 | -7.73 | 39.26% | CHEMBL1642757 |
| Morphine | OPRK_HUMAN | opioid receptor kappa 1 | -9.06 | -8.55 | -7.70 | 100.00% | CHEMBL70 |
| Diclophenac | OPRM_MOUSE | Mu-type opioid receptor | -7.68 | -7.10 | N/A | 30.19% | CHEMBL596 |
| Morphine | OPRM_MOUSE | Mu-type opioid receptor | -8.29 | -8.66 | N/A | 100.00% | CHEMBL70 |
| Diclophenac | OPRX_HUMAN | opioid related nociceptin receptor 1 | -7.36 | -7.11 | -6.85 | 34.78% | CHEMBL317152 |
| Morphine | OPRX_HUMAN | opioid related nociceptin receptor 1 | -8.07 | -7.12 | -7.42 | 94.38% | CHEMBL3262362 |
| Diclophenac | P2RX3_HUMAN | purinergic receptor P2X 3 | -5.89 | -4.93 | -5.45 | 45.71% | CHEMBL3958199 |
| Morphine | P2RX3_HUMAN | purinergic receptor P2X 3 | -6.39 | -5.93 | -6.38 | 35.47% | CHEMBL3679847 |
| Diclophenac | P2Y12_HUMAN | purinergic receptor P2Y12 | -8.30 | -6.08 | -7.72 | 30.00% | CHEMBL223344 |
| Morphine | P2Y12_HUMAN | purinergic receptor P2Y12 | -6.65 | -4.47 | -6.12 | 28.47% | CHEMBL2172277 |
| Diclophenac | PAR1_HUMAN | coagulation factor II thrombin receptor | -8.31 | N/A | N/A | 29.75% | CHEMBL2049115 |
| Morphine | PAR1_HUMAN | coagulation factor II thrombin receptor | -9.16 | N/A | N/A | 34.35% | CHEMBL3086083 |
| Diclophenac | PDE4B_HUMAN | phosphodiesterase 4B | -8.10 | -8.03 | -8.13 | 51.82% | CHEMBL3315269 |
| Morphine | PDE4B_HUMAN | phosphodiesterase 4B | -8.01 | -7.41 | -8.38 | 45.95% | CHEMBL144499 |
| Diclophenac | PDE5A_HUMAN | phosphodiesterase 5A | -7.21 | -8.35 | -7.97 | 28.36% | CHEMBL332898 |
| Morphine | PDE5A_HUMAN | phosphodiesterase 5A | -7.82 | -8.14 | -8.24 | 31.75% | CHEMBL190423 |
| Diclophenac | PERM_HUMAN | myeloperoxidase | -7.60 | -7.78 | -7.78 | 41.57% | CHEMBL686 |
| Morphine | PERM_HUMAN | myeloperoxidase | -7.90 | -7.96 | -8.02 | 35.57% | CHEMBL490 |
| Diclophenac | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -6.22 | -8.31 | -8.48 | 100.00% | CHEMBL139 |
| Morphine | PGH1_SHEEP | Prostaglandin G/H synthase 1 | -3.16 | -7.62 | -7.03 | 34.85% | CHEMBL229957 |
| Diclophenac | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | -7.37 | -7.98 | -8.14 | 100.00% | CHEMBL139 |
| Morphine | PGH2_HUMAN | prostaglandin-endoperoxide synthase 2 | 1.36 | -6.24 | -6.70 | 34.92% | CHEMBL13988 |
| Diclophenac | PPAP_HUMAN | acid phosphatase 3 | -7.69 | N/A | N/A | 17.24% | CHEMBL501717 |
| Morphine | PPAP_HUMAN | acid phosphatase 3 | -8.39 | N/A | N/A | 20.39% | CHEMBL507996 |
| Diclophenac | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -7.57 | -7.17 | -7.92 | 38.89% | CHEMBL167963 |
| Morphine | PPARG_HUMAN | peroxisome proliferator activated receptor gamma | -6.50 | -5.87 | -6.23 | 43.24% | CHEMBL1836977 |
| Diclophenac | PRGR_HUMAN | progesterone receptor | -8.19 | -8.40 | -7.81 | 45.87% | CHEMBL117612 |
| Morphine | PRGR_HUMAN | progesterone receptor | -9.04 | -9.47 | -8.73 | 40.72% | CHEMBL51933 |
| Diclophenac | PTGES_HUMAN | prostaglandin E synthase | -6.52 | N/A | N/A | 35.14% | CHEMBL1683859 |
| Morphine | PTGES_HUMAN | prostaglandin E synthase | -6.74 | N/A | N/A | 37.75% | CHEMBL3753433 |
| Diclophenac | SC6A4_HUMAN | solute carrier family 6 member 4 | -8.20 | -8.33 | -8.76 | 46.53% | CHEMBL415 |
| Morphine | SC6A4_HUMAN | solute carrier family 6 member 4 | -9.44 | -9.20 | -9.29 | 46.48% | CHEMBL434728 |
| Diclophenac | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -7.61 | N/A | N/A | 37.41% | CHEMBL3581050 |
| Morphine | SCN9A_HUMAN | sodium voltage-gated channel alpha subunit 9 | -6.25 | N/A | N/A | 40.00% | CHEMBL3662107 |
| Diclophenac | TLR4_HUMAN | toll like receptor 4 | -7.37 | -7.23 | -7.52 | 23.74% | CHEMBL2419459 |
| Morphine | TLR4_HUMAN | toll like receptor 4 | -8.26 | -8.29 | -7.17 | 37.84% | CHEMBL3261029 |
| Diclophenac | TNFA_HUMAN | tumor necrosis factor | -7.40 | N/A | N/A | 30.83% | CHEMBL1612423 |
| Morphine | TNFA_HUMAN | tumor necrosis factor | -7.88 | N/A | N/A | 54.46% | CHEMBL2337619 |
| Diclophenac | TRBM_HUMAN | thrombomodulin | -6.91 | -6.85 | N/A | N/A | N/A |
| Morphine | TRBM_HUMAN | thrombomodulin | -7.23 | -7.14 | N/A | N/A | N/A |
| Diclophenac | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -7.40 | -6.18 | N/A | N/A | N/A |
| Morphine | TRPM4_HUMAN | transient receptor potential cation channel subfamily M member 4 | -7.73 | -6.69 | N/A | N/A | N/A |
| Diclophenac | TRPM8_FICAL | Uncharacterized protein | -8.27 | N/A | N/A | N/A | N/A |
| Morphine | TRPM8_FICAL | Uncharacterized protein | -8.65 | N/A | N/A | N/A | N/A |
| Diclophenac | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -7.36 | N/A | N/A | 37.74% | CHEMBL258265 |
| Morphine | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 | -7.83 | N/A | N/A | 42.71% | CHEMBL97968 |
| Diclophenac | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -6.84 | -7.88 | N/A | N/A | N/A |
| Morphine | TRPV2_RABIT | Transient receptor potential cation channel subfamily V member 2 | -8.54 | -8.15 | N/A | N/A | N/A |
| Diclophenac | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -6.34 | -6.87 | N/A | 30.89% | CHEMBL3828278 |
| Morphine | TRPV3_HUMAN | transient receptor potential cation channel subfamily V member 3 | -6.52 | -7.86 | N/A | 44.88% | CHEMBL3664218 |
| Diclophenac | TRXR1_HUMAN | thioredoxin reductase 1 | -7.83 | -7.25 | -6.24 | N/A | N/A |
| Morphine | TRXR1_HUMAN | thioredoxin reductase 1 | -8.46 | -8.10 | -7.03 | N/A | N/A |
| Diclophenac | TRY1_HUMAN | serine protease 1 | -6.30 | N/A | N/A | 34.23% | CHEMBL3926197 |
| Morphine | TRY1_HUMAN | serine protease 1 | -6.01 | N/A | N/A | 33.22% | CHEMBL73970 |