| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||||
| Galidesivir | 2A_HE71 | Genome polyprotein | -7.50 | N/A | N/A | N/A | N/A |
| Tenofovir | 2A_HE71 | Genome polyprotein | -7.25 | N/A | N/A | N/A | N/A |
| Galidesivir | 2A_HE71M | Genome polyprotein | -7.39 | N/A | N/A | N/A | N/A |
| Tenofovir | 2A_HE71M | Genome polyprotein | -6.99 | N/A | N/A | N/A | N/A |
| Galidesivir | 2C_HE71 | Genome polyprotein | -5.33 | -5.74 | N/A | N/A | N/A |
| Tenofovir | 2C_HE71 | Genome polyprotein | -4.53 | -6.14 | N/A | N/A | N/A |
| Galidesivir | 3A_9ENTO | Genome polyprotein | -5.96 | N/A | N/A | N/A | N/A |
| Tenofovir | 3A_9ENTO | Genome polyprotein | -4.44 | N/A | N/A | N/A | N/A |
| Galidesivir | 3A_HE71M | Genome polyprotein | -5.18 | N/A | N/A | N/A | N/A |
| Tenofovir | 3A_HE71M | Genome polyprotein | -4.51 | N/A | N/A | N/A | N/A |
| Galidesivir | 3A_HED68 | Genome polyprotein | -5.67 | N/A | N/A | N/A | N/A |
| Tenofovir | 3A_HED68 | Genome polyprotein | -4.28 | N/A | N/A | N/A | N/A |
| Galidesivir | 3C_HE71 | Genome polyprotein | -5.19 | -6.02 | N/A | N/A | N/A |
| Tenofovir | 3C_HE71 | Genome polyprotein | -5.03 | -5.60 | N/A | N/A | N/A |
| Galidesivir | 3C_HED68 | Genome polyprotein | -5.57 | N/A | N/A | N/A | N/A |
| Tenofovir | 3C_HED68 | Genome polyprotein | -4.81 | N/A | N/A | N/A | N/A |
| Galidesivir | 3D_HE71 | Genome polyprotein | -7.36 | N/A | N/A | N/A | N/A |
| Tenofovir | 3D_HE71 | Genome polyprotein | -6.42 | N/A | N/A | N/A | N/A |
| Galidesivir | 3D_HED68 | Genome polyprotein | -7.58 | N/A | N/A | N/A | N/A |
| Tenofovir | 3D_HED68 | Genome polyprotein | -6.49 | N/A | N/A | N/A | N/A |
| Galidesivir | ACE2_HUMAN | angiotensin converting enzyme 2 | -7.67 | N/A | N/A | 33.33% | CHEMBL1240682 |
| Tenofovir | ACE2_HUMAN | angiotensin converting enzyme 2 | -7.08 | N/A | N/A | 18.62% | CHEMBL429844 |
| Galidesivir | CAPSD_9CALI | Capsid protein | -6.05 | -6.87 | -7.23 | N/A | N/A |
| Tenofovir | CAPSD_9CALI | Capsid protein | -5.83 | -5.62 | -6.56 | N/A | N/A |
| Galidesivir | CAPSD_9ENTO | Genome polyprotein | -8.27 | N/A | N/A | N/A | N/A |
| Tenofovir | CAPSD_9ENTO | Genome polyprotein | -7.22 | N/A | N/A | N/A | N/A |
| Galidesivir | CAPSD_DEN2P | Genome polyprotein | -5.24 | N/A | N/A | N/A | N/A |
| Tenofovir | CAPSD_DEN2P | Genome polyprotein | -5.16 | N/A | N/A | N/A | N/A |
| Galidesivir | CAPSD_HCV77 | Genome polyprotein | -5.09 | N/A | N/A | 36.27% | CHEMBL4112685 |
| Tenofovir | CAPSD_HCV77 | Genome polyprotein | -4.14 | N/A | N/A | 32.06% | CHEMBL3696817 |
| Galidesivir | CAPSD_HED68 | Capsid protein VP0 | -6.81 | -7.51 | N/A | N/A | N/A |
| Tenofovir | CAPSD_HED68 | Capsid protein VP0 | -6.66 | -6.97 | N/A | N/A | N/A |
| Galidesivir | CAPSD_ZIKV | Core protein | -5.27 | -5.05 | N/A | N/A | N/A |
| Tenofovir | CAPSD_ZIKV | Core protein | -4.44 | -4.39 | N/A | N/A | N/A |
| Galidesivir | DPM_HHV1K | DNA polymerase catalytic subunit | -7.76 | N/A | N/A | 27.78% | CHEMBL481172 |
| Tenofovir | DPM_HHV1K | DNA polymerase catalytic subunit | -6.41 | N/A | N/A | 14.57% | CHEMBL481172 |
| Galidesivir | E1_9HEPC | Envelope glycoprotein E1 | -5.27 | N/A | N/A | N/A | N/A |
| Tenofovir | E1_9HEPC | Envelope glycoprotein E1 | -4.49 | N/A | N/A | N/A | N/A |
| Galidesivir | E1_HCV77 | Genome polyprotein | -3.65 | N/A | N/A | 36.27% | CHEMBL4112685 |
| Tenofovir | E1_HCV77 | Genome polyprotein | -3.00 | N/A | N/A | 32.06% | CHEMBL3696817 |
| Galidesivir | E1_HCVJ1 | Genome polyprotein | -4.25 | N/A | N/A | N/A | N/A |
| Tenofovir | E1_HCVJ1 | Genome polyprotein | -3.45 | N/A | N/A | N/A | N/A |
| Galidesivir | E2_9HEPC | Core protein precursor | -7.26 | N/A | N/A | N/A | N/A |
| Tenofovir | E2_9HEPC | Core protein precursor | -7.21 | N/A | N/A | N/A | N/A |
| Galidesivir | E2_HCV77 | Genome polyprotein | -5.73 | N/A | N/A | 36.27% | CHEMBL4112685 |
| Tenofovir | E2_HCV77 | Genome polyprotein | -4.87 | N/A | N/A | 32.06% | CHEMBL3696817 |
| Galidesivir | ENV_9FLAV | Envelope protein E | -5.71 | N/A | N/A | N/A | N/A |
| Tenofovir | ENV_9FLAV | Envelope protein E | -4.70 | N/A | N/A | N/A | N/A |
| Galidesivir | ENV_DEN1B | Genome polyprotein | -4.60 | N/A | N/A | N/A | N/A |
| Tenofovir | ENV_DEN1B | Genome polyprotein | -4.79 | N/A | N/A | N/A | N/A |
| Galidesivir | ENV_DEN2P | Genome polyprotein | -6.56 | N/A | N/A | N/A | N/A |
| Tenofovir | ENV_DEN2P | Genome polyprotein | -6.17 | N/A | N/A | N/A | N/A |
| Galidesivir | ENV_DEN3P | Genome polyprotein | -5.26 | N/A | N/A | N/A | N/A |
| Tenofovir | ENV_DEN3P | Genome polyprotein | -4.90 | N/A | N/A | N/A | N/A |
| Galidesivir | ENV_HHV2H | Envelope glycoprotein H | -5.92 | N/A | N/A | N/A | N/A |
| Tenofovir | ENV_HHV2H | Envelope glycoprotein H | -5.32 | N/A | N/A | N/A | N/A |
| Galidesivir | ENV_ZIKV | Core protein | -6.18 | N/A | N/A | N/A | N/A |
| Tenofovir | ENV_ZIKV | Core protein | -5.08 | N/A | N/A | N/A | N/A |
| Galidesivir | ENV_ZIKVK | Genome polyprotein | -6.38 | N/A | N/A | N/A | N/A |
| Tenofovir | ENV_ZIKVK | Genome polyprotein | -5.19 | N/A | N/A | N/A | N/A |
| Galidesivir | G1_ADNV | Envelope polyprotein | -4.18 | -6.32 | -6.04 | N/A | N/A |
| Tenofovir | G1_ADNV | Envelope polyprotein | -3.79 | -5.39 | -5.34 | N/A | N/A |
| Galidesivir | G2_ADNV | Envelope polyprotein | -8.14 | -7.82 | -6.09 | N/A | N/A |
| Tenofovir | G2_ADNV | Envelope polyprotein | -6.99 | -6.41 | -5.65 | N/A | N/A |
| Galidesivir | GB_HHV11 | Envelope glycoprotein B | -6.66 | N/A | N/A | N/A | N/A |
| Tenofovir | GB_HHV11 | Envelope glycoprotein B | -6.58 | N/A | N/A | N/A | N/A |
| Galidesivir | GB_HHV1K | Envelope glycoprotein B | -6.79 | -7.06 | N/A | N/A | N/A |
| Tenofovir | GB_HHV1K | Envelope glycoprotein B | -6.08 | -5.71 | N/A | N/A | N/A |
| Galidesivir | GD_9ALPH | Glycoprotein D | -6.27 | -5.69 | N/A | N/A | N/A |
| Tenofovir | GD_9ALPH | Glycoprotein D | -6.20 | -5.05 | N/A | N/A | N/A |
| Galidesivir | GD_HHV1 | Glycoprotein D | -6.49 | N/A | N/A | N/A | N/A |
| Tenofovir | GD_HHV1 | Glycoprotein D | -5.08 | N/A | N/A | N/A | N/A |
| Galidesivir | GP160_HIV1 | Envelope glycoprotein gp160 | -6.32 | -6.14 | -5.79 | N/A | N/A |
| Tenofovir | GP160_HIV1 | Envelope glycoprotein gp160 | -5.32 | -5.46 | -5.03 | N/A | N/A |
| Galidesivir | GP160_HIV2 | Envelope glycoprotein gp160 | -6.89 | N/A | N/A | N/A | N/A |
| Tenofovir | GP160_HIV2 | Envelope glycoprotein gp160 | -5.27 | N/A | N/A | N/A | N/A |
| Galidesivir | GP_EBOV | Envelope glycoprotein | -6.07 | -5.69 | -5.73 | 31.20% | CHEMBL3125895 |
| Tenofovir | GP_EBOV | Envelope glycoprotein | -5.67 | -5.41 | -5.59 | 14.81% | CHEMBL3125895 |
| Galidesivir | GP_LASSJ | Pre-glycoprotein polyprotein GP complex | -5.91 | -6.92 | N/A | N/A | N/A |
| Tenofovir | GP_LASSJ | Pre-glycoprotein polyprotein GP complex | -5.54 | -6.41 | N/A | N/A | N/A |
| Galidesivir | HA_A-H10N7 | Hemagglutinin | -6.11 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H10N7 | Hemagglutinin | -5.43 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_A-H10N8 | Hemagglutinin | -5.46 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H10N8 | Hemagglutinin | -5.26 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_A-H13N6 | Hemagglutinin | -6.11 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H13N6 | Hemagglutinin | -5.43 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_A-H14N6 | Hemagglutinin | -5.65 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H14N6 | Hemagglutinin | -5.54 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_A-H15N9 | Hemagglutinin | -6.43 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H15N9 | Hemagglutinin | -6.20 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_A-H17N10 | Hemagglutinin | -5.79 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H17N10 | Hemagglutinin | -5.44 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_A-H18N11 | Hemagglutinin | -5.77 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H18N11 | Hemagglutinin | -5.00 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_A-H1N1 | Hemagglutinin | -5.73 | -5.62 | N/A | N/A | N/A |
| Tenofovir | HA_A-H1N1 | Hemagglutinin | -4.95 | -5.07 | N/A | N/A | N/A |
| Galidesivir | HA_A-H2N2 | Hemagglutinin | -6.24 | -6.19 | N/A | N/A | N/A |
| Tenofovir | HA_A-H2N2 | Hemagglutinin | -5.24 | -5.21 | N/A | N/A | N/A |
| Galidesivir | HA_A-H3N2 | Hemagglutinin | -6.40 | -6.17 | -5.49 | N/A | N/A |
| Tenofovir | HA_A-H3N2 | Hemagglutinin | -5.74 | -5.01 | -5.15 | N/A | N/A |
| Galidesivir | HA_A-H3N8 | Hemagglutinin | -5.51 | -5.60 | -5.57 | N/A | N/A |
| Tenofovir | HA_A-H3N8 | Hemagglutinin | -5.15 | -5.20 | -5.39 | N/A | N/A |
| Galidesivir | HA_A-H5N1 | Hemagglutinin | -6.30 | -6.09 | -5.85 | N/A | N/A |
| Tenofovir | HA_A-H5N1 | Hemagglutinin | -5.95 | -5.76 | -5.65 | N/A | N/A |
| Galidesivir | HA_A-H5N3 | Hemagglutinin | -6.08 | -5.70 | N/A | N/A | N/A |
| Tenofovir | HA_A-H5N3 | Hemagglutinin | -5.62 | -5.14 | N/A | N/A | N/A |
| Galidesivir | HA_A-H6N1 | Hemagglutinin | -5.46 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H6N1 | Hemagglutinin | -5.26 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_A-H6N6 | Hemagglutinin | -5.71 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H6N6 | Hemagglutinin | -5.33 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_A-H7N2 | Hemagglutinin | -5.66 | -5.44 | -5.82 | N/A | N/A |
| Tenofovir | HA_A-H7N2 | Hemagglutinin | -5.22 | -5.20 | -4.97 | N/A | N/A |
| Galidesivir | HA_A-H7N7 | Hemagglutinin | -6.41 | -6.22 | N/A | N/A | N/A |
| Tenofovir | HA_A-H7N7 | Hemagglutinin | -5.58 | -5.32 | N/A | N/A | N/A |
| Galidesivir | HA_A-H7N9 | Hemagglutinin | -6.54 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_A-H7N9 | Hemagglutinin | -5.11 | N/A | N/A | N/A | N/A |
| Galidesivir | HA_INFB | Hemagglutinin | -6.01 | -6.03 | N/A | N/A | N/A |
| Tenofovir | HA_INFB | Hemagglutinin | -5.90 | -5.69 | N/A | N/A | N/A |
| Galidesivir | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -5.42 | N/A | N/A | N/A | N/A |
| Tenofovir | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -4.33 | N/A | N/A | N/A | N/A |
| Galidesivir | HE_BCV | Hemagglutinin-esterase | -6.12 | -5.54 | N/A | N/A | N/A |
| Tenofovir | HE_BCV | Hemagglutinin-esterase | -6.03 | -5.81 | N/A | N/A | N/A |
| Galidesivir | HE_HCoV-OC43 | Hemagglutinin-esterase | -5.00 | N/A | N/A | N/A | N/A |
| Tenofovir | HE_HCoV-OC43 | Hemagglutinin-esterase | -5.07 | N/A | N/A | N/A | N/A |
| Galidesivir | HE_MHV | Hemagglutinin-esterase | -5.50 | N/A | N/A | N/A | N/A |
| Tenofovir | HE_MHV | Hemagglutinin-esterase | -4.99 | N/A | N/A | N/A | N/A |
| Galidesivir | IN_HIV1 | Gag-Pol polyprotein | -5.14 | -4.72 | N/A | N/A | N/A |
| Tenofovir | IN_HIV1 | Gag-Pol polyprotein | -4.29 | -4.74 | N/A | N/A | N/A |
| Galidesivir | MD_HKU4 | Replicase polyprotein 1ab | -7.70 | -7.91 | -7.92 | N/A | N/A |
| Tenofovir | MD_HKU4 | Replicase polyprotein 1ab | -7.22 | -6.49 | -6.94 | N/A | N/A |
| Galidesivir | MD_MERs | Replicase polyprotein 1a | -7.52 | -6.98 | N/A | N/A | N/A |
| Tenofovir | MD_MERs | Replicase polyprotein 1a | -6.89 | -6.91 | N/A | N/A | N/A |
| Galidesivir | MEM_9FLAV | Core protein | -5.06 | N/A | N/A | N/A | N/A |
| Tenofovir | MEM_9FLAV | Core protein | -4.34 | N/A | N/A | N/A | N/A |
| Galidesivir | MTASE_SARS2 | Methyltransferase | -6.08 | N/A | N/A | N/A | N/A |
| Galidesivir | MTASE_SARS2 | Methyltransferase | -7.01 | N/A | N/A | N/A | N/A |
| Tenofovir | MTASE_SARS2 | Methyltransferase | -5.74 | N/A | N/A | N/A | N/A |
| Tenofovir | MTASE_SARS2 | Methyltransferase | -6.92 | N/A | N/A | N/A | N/A |
| Galidesivir | MX2_A-H5N1 | Matrix protein 2 | -9.63 | N/A | N/A | N/A | N/A |
| Tenofovir | MX2_A-H5N1 | Matrix protein 2 | -8.28 | N/A | N/A | N/A | N/A |
| Galidesivir | MX_9MONO | Matrix protein VP40 | -7.15 | N/A | N/A | N/A | N/A |
| Tenofovir | MX_9MONO | Matrix protein VP40 | -6.28 | N/A | N/A | N/A | N/A |
| Galidesivir | MX_LASSJ | RING finger protein Z | -5.53 | N/A | N/A | N/A | N/A |
| Tenofovir | MX_LASSJ | RING finger protein Z | -5.11 | N/A | N/A | N/A | N/A |
| Galidesivir | NA_A-H11N6 | Neuraminidase | -7.72 | -7.24 | -7.35 | N/A | N/A |
| Tenofovir | NA_A-H11N6 | Neuraminidase | -6.51 | -6.57 | -6.50 | N/A | N/A |
| Galidesivir | NA_A-H11N9 | Neuraminidase | -6.25 | -7.48 | -7.57 | N/A | N/A |
| Tenofovir | NA_A-H11N9 | Neuraminidase | -5.36 | -6.53 | -6.66 | N/A | N/A |
| Galidesivir | NA_A-H12N5 | Neuraminidase | -7.25 | -7.65 | -7.70 | N/A | N/A |
| Tenofovir | NA_A-H12N5 | Neuraminidase | -6.69 | -6.72 | -6.57 | N/A | N/A |
| Galidesivir | NA_A-H13N9 | Neuraminidase | -5.95 | N/A | N/A | N/A | N/A |
| Tenofovir | NA_A-H13N9 | Neuraminidase | -5.70 | N/A | N/A | N/A | N/A |
| Galidesivir | NA_A-H17N10 | Neuraminidase | -6.28 | N/A | N/A | N/A | N/A |
| Tenofovir | NA_A-H17N10 | Neuraminidase | -6.17 | N/A | N/A | N/A | N/A |
| Galidesivir | NA_A-H18N11 | Neuraminidase | -5.59 | N/A | N/A | N/A | N/A |
| Tenofovir | NA_A-H18N11 | Neuraminidase | -5.23 | N/A | N/A | N/A | N/A |
| Galidesivir | NA_A-H1N1 | Neuraminidase | -7.25 | N/A | N/A | N/A | N/A |
| Tenofovir | NA_A-H1N1 | Neuraminidase | -6.33 | N/A | N/A | N/A | N/A |
| Galidesivir | NA_A-H2N2 | Neuraminidase | -7.54 | -7.32 | -6.45 | N/A | N/A |
| Tenofovir | NA_A-H2N2 | Neuraminidase | -6.90 | -6.68 | -6.25 | N/A | N/A |
| Galidesivir | NA_A-H3N2 | Ig heavy chain Mem5 | -6.34 | -7.09 | N/A | N/A | N/A |
| Tenofovir | NA_A-H3N2 | Ig heavy chain Mem5 | -6.50 | -6.24 | N/A | N/A | N/A |
| Galidesivir | NA_A-H3N8 | Neuraminidase | -7.38 | -7.49 | -7.34 | 25.23% | CHEMBL4285767 |
| Tenofovir | NA_A-H3N8 | Neuraminidase | -6.61 | -6.90 | -6.90 | 14.67% | CHEMBL222813 |
| Galidesivir | NA_A-H5N1 | Neuraminidase | -7.04 | N/A | N/A | N/A | N/A |
| Tenofovir | NA_A-H5N1 | Neuraminidase | -6.47 | N/A | N/A | N/A | N/A |
| Galidesivir | NA_A-H7N9 | Neuraminidase | -7.43 | -7.80 | -7.35 | N/A | N/A |
| Tenofovir | NA_A-H7N9 | Neuraminidase | -5.99 | -6.42 | -6.09 | N/A | N/A |
| Galidesivir | NA_INFB | Neuraminidase | -7.30 | -7.50 | N/A | 25.79% | CHEMBL4175983 |
| Tenofovir | NA_INFB | Neuraminidase | -6.49 | -6.66 | N/A | 18.59% | CHEMBL195288 |
| Galidesivir | NP_9ADNV | Nucleoprotein | -4.82 | -6.45 | N/A | N/A | N/A |
| Tenofovir | NP_9ADNV | Nucleoprotein | -4.42 | -6.41 | N/A | N/A | N/A |
| Galidesivir | NP_A-H1N1 | Nucleoprotein | -5.43 | -5.53 | -7.47 | N/A | N/A |
| Tenofovir | NP_A-H1N1 | Nucleoprotein | -4.87 | -5.53 | -6.32 | N/A | N/A |
| Galidesivir | NP_A-H5N1 | Nucleoprotein | -6.28 | N/A | N/A | N/A | N/A |
| Tenofovir | NP_A-H5N1 | Nucleoprotein | -5.94 | N/A | N/A | N/A | N/A |
| Galidesivir | NP_EBOZM | Nucleoprotein | -5.26 | -5.67 | -6.08 | N/A | N/A |
| Tenofovir | NP_EBOZM | Nucleoprotein | -5.10 | -5.66 | -5.87 | N/A | N/A |
| Galidesivir | NP_HCoV-NL63 | Nucleoprotein | -6.16 | N/A | N/A | N/A | N/A |
| Tenofovir | NP_HCoV-NL63 | Nucleoprotein | -5.89 | N/A | N/A | N/A | N/A |
| Galidesivir | NP_HCoV-OC43 | Nucleoprotein | -7.41 | -6.44 | -6.12 | 14.20% | CHEMBL3233481 |
| Tenofovir | NP_HCoV-OC43 | Nucleoprotein | -6.73 | -5.62 | -5.61 | 9.22% | CHEMBL3233481 |
| Galidesivir | NP_INFB | Nucleoprotein | -4.73 | N/A | N/A | N/A | N/A |
| Tenofovir | NP_INFB | Nucleoprotein | -5.37 | N/A | N/A | N/A | N/A |
| Galidesivir | NP_INFD | NP | -4.65 | N/A | N/A | N/A | N/A |
| Tenofovir | NP_INFD | NP | -4.32 | N/A | N/A | N/A | N/A |
| Galidesivir | NP_LASSJ | Nucleoprotein | -7.87 | -8.07 | -5.01 | N/A | N/A |
| Tenofovir | NP_LASSJ | Nucleoprotein | -7.82 | -7.22 | -4.06 | N/A | N/A |
| Galidesivir | NP_SARS | Nucleoprotein | -6.47 | N/A | N/A | N/A | N/A |
| Tenofovir | NP_SARS | Nucleoprotein | -5.63 | N/A | N/A | N/A | N/A |
| Galidesivir | NS1_9CALI | NTPase | -5.21 | -5.38 | -5.81 | N/A | N/A |
| Tenofovir | NS1_9CALI | NTPase | -5.45 | -4.87 | -5.17 | N/A | N/A |
| Galidesivir | NS1_9FLAV | Non-structural protein 1 | -5.82 | N/A | N/A | N/A | N/A |
| Tenofovir | NS1_9FLAV | Non-structural protein 1 | -5.34 | N/A | N/A | N/A | N/A |
| Galidesivir | NS1_DEN1W | Genome polyprotein | -5.75 | N/A | N/A | N/A | N/A |
| Tenofovir | NS1_DEN1W | Genome polyprotein | -4.76 | N/A | N/A | N/A | N/A |
| Galidesivir | NS1_ZIKV | Core protein | -6.44 | -6.49 | -6.35 | N/A | N/A |
| Tenofovir | NS1_ZIKV | Core protein | -6.68 | -6.73 | -5.77 | N/A | N/A |
| Galidesivir | NS2A_9FLAV | Core protein | -4.33 | N/A | N/A | N/A | N/A |
| Tenofovir | NS2A_9FLAV | Core protein | -3.60 | N/A | N/A | N/A | N/A |
| Galidesivir | NS2B_DEN1W | Genome polyprotein | -6.94 | N/A | N/A | N/A | N/A |
| Tenofovir | NS2B_DEN1W | Genome polyprotein | -6.47 | N/A | N/A | N/A | N/A |
| Galidesivir | NS2B_DEN2P | Genome polyprotein | -6.30 | -6.92 | N/A | N/A | N/A |
| Tenofovir | NS2B_DEN2P | Genome polyprotein | -5.92 | -6.43 | N/A | N/A | N/A |
| Galidesivir | NS2B_ZIKV | Genome polyprotein | -6.52 | -6.69 | N/A | N/A | N/A |
| Tenofovir | NS2B_ZIKV | Genome polyprotein | -5.94 | -6.34 | N/A | N/A | N/A |
| Galidesivir | NS2B_ZIKVF | Genome polyprotein | -6.17 | N/A | N/A | N/A | N/A |
| Tenofovir | NS2B_ZIKVF | Genome polyprotein | -5.66 | N/A | N/A | N/A | N/A |
| Galidesivir | NS3_9FLAV | Core protein | -7.33 | N/A | N/A | N/A | N/A |
| Tenofovir | NS3_9FLAV | Core protein | -6.52 | N/A | N/A | N/A | N/A |
| Galidesivir | NS3_DEN4T | Genome polyprotein | -6.87 | -6.78 | N/A | N/A | N/A |
| Tenofovir | NS3_DEN4T | Genome polyprotein | -6.54 | -6.59 | N/A | N/A | N/A |
| Galidesivir | NS3_HCV1A | Genome polyprotein | -6.40 | -5.66 | -7.19 | 36.27% | CHEMBL4112685 |
| Tenofovir | NS3_HCV1A | Genome polyprotein | -6.58 | -5.41 | -6.55 | 32.06% | CHEMBL3696817 |
| Galidesivir | NS3_HCV1B | Genome polyprotein | -7.47 | -6.96 | -5.91 | 27.68% | CHEMBL3954962 |
| Tenofovir | NS3_HCV1B | Genome polyprotein | -6.44 | -6.08 | -5.19 | 15.15% | CHEMBL3125634 |
| Galidesivir | NS3_HCV3A | Genome polyprotein | -6.47 | -6.08 | -6.32 | N/A | N/A |
| Tenofovir | NS3_HCV3A | Genome polyprotein | -5.65 | -5.75 | -5.54 | N/A | N/A |
| Galidesivir | NS3_ZIKV | Genome polyprotein | -7.23 | N/A | N/A | N/A | N/A |
| Tenofovir | NS3_ZIKV | Genome polyprotein | -6.48 | N/A | N/A | N/A | N/A |
| Galidesivir | NS5B_HCV1A | Genome polyprotein | -7.27 | -7.21 | -7.52 | 41.82% | CHEMBL353549 |
| Tenofovir | NS5B_HCV1A | Genome polyprotein | -6.69 | -6.46 | -6.55 | 21.88% | CHEMBL353549 |
| Galidesivir | NS5B_HCV1B | Genome polyprotein | -6.93 | -6.68 | -6.52 | 33.74% | CHEMBL3645200 |
| Tenofovir | NS5B_HCV1B | Genome polyprotein | -5.75 | -5.83 | -5.90 | 20.68% | CHEMBL3911921 |
| Galidesivir | NS5B_HCV2A | Genome polyprotein | -8.15 | -8.14 | N/A | 30.05% | CHEMBL3127326 |
| Tenofovir | NS5B_HCV2A | Genome polyprotein | -6.93 | -6.98 | N/A | 12.77% | CHEMBL3127326 |
| Galidesivir | NS5_9FLAV | Core protein | -6.89 | N/A | N/A | N/A | N/A |
| Tenofovir | NS5_9FLAV | Core protein | -6.49 | N/A | N/A | N/A | N/A |
| Galidesivir | NS5_DEN3S | Genome polyprotein | -6.33 | -6.61 | N/A | N/A | N/A |
| Tenofovir | NS5_DEN3S | Genome polyprotein | -6.25 | -6.03 | N/A | N/A | N/A |
| Galidesivir | NS5_ZIKV | Genome polyprotein | -7.16 | -5.56 | N/A | N/A | N/A |
| Tenofovir | NS5_ZIKV | Genome polyprotein | -6.86 | -4.72 | N/A | N/A | N/A |
| Galidesivir | NS5_ZIKVF | Genome polyprotein | -6.78 | N/A | N/A | N/A | N/A |
| Tenofovir | NS5_ZIKVF | Genome polyprotein | -6.67 | N/A | N/A | N/A | N/A |
| Galidesivir | NS6_9CALI | NTPase | -4.21 | -6.12 | -5.47 | N/A | N/A |
| Tenofovir | NS6_9CALI | NTPase | -4.21 | -5.68 | -5.45 | N/A | N/A |
| Galidesivir | NSP15_SARS | Replicase polyprotein 1ab | -6.02 | N/A | N/A | 22.22% | CHEMBL2441741 |
| Tenofovir | NSP15_SARS | Replicase polyprotein 1ab | -5.12 | N/A | N/A | 14.04% | CHEMBL2441741 |
| Galidesivir | NSP15_SARS2 | Replicase polyprotein 1ab | -6.58 | N/A | N/A | N/A | N/A |
| Tenofovir | NSP15_SARS2 | Replicase polyprotein 1ab | -6.49 | N/A | N/A | N/A | N/A |
| Galidesivir | NSP1_INFB | Non-structural protein 1 | -4.85 | -5.06 | N/A | N/A | N/A |
| Tenofovir | NSP1_INFB | Non-structural protein 1 | -4.47 | -4.85 | N/A | N/A | N/A |
| Galidesivir | NSP1_SARS | Replicase polyprotein 1ab | -6.15 | N/A | N/A | 22.22% | CHEMBL2441741 |
| Tenofovir | NSP1_SARS | Replicase polyprotein 1ab | -5.58 | N/A | N/A | 14.04% | CHEMBL2441741 |
| Galidesivir | NSP3_HCoV-229E | Replicase polyprotein 1a | -7.66 | N/A | N/A | N/A | N/A |
| Tenofovir | NSP3_HCoV-229E | Replicase polyprotein 1a | -6.97 | N/A | N/A | N/A | N/A |
| Galidesivir | NSP3_IBV | Replicase polyprotein 1a | -7.77 | N/A | N/A | N/A | N/A |
| Tenofovir | NSP3_IBV | Replicase polyprotein 1a | -7.46 | N/A | N/A | N/A | N/A |
| Galidesivir | NSP3_MHV | Replicase polyprotein 1ab | -6.06 | N/A | N/A | N/A | N/A |
| Tenofovir | NSP3_MHV | Replicase polyprotein 1ab | -5.38 | N/A | N/A | N/A | N/A |
| Galidesivir | NSP3_SARS2 | Replicase polyprotein 1ab | -6.73 | N/A | N/A | N/A | N/A |
| Tenofovir | NSP3_SARS2 | Replicase polyprotein 1ab | -6.54 | N/A | N/A | N/A | N/A |
| Galidesivir | NSP9_HCoV-229E | Replicase polyprotein 1ab | -5.61 | -5.55 | N/A | N/A | N/A |
| Tenofovir | NSP9_HCoV-229E | Replicase polyprotein 1ab | -5.31 | -4.92 | N/A | N/A | N/A |
| Galidesivir | PA_A-H17N10 | Polymerase acidic protein | -7.06 | N/A | N/A | N/A | N/A |
| Tenofovir | PA_A-H17N10 | Polymerase acidic protein | -6.35 | N/A | N/A | N/A | N/A |
| Galidesivir | PA_A-H1N1 | Polymerase acidic protein | -6.79 | -7.03 | -6.85 | N/A | N/A |
| Tenofovir | PA_A-H1N1 | Polymerase acidic protein | -6.53 | -6.33 | -6.33 | N/A | N/A |
| Galidesivir | PA_A-H5N1 | Polymerase acidic protein | -7.08 | -6.96 | -7.03 | N/A | N/A |
| Tenofovir | PA_A-H5N1 | Polymerase acidic protein | -6.87 | -6.87 | -6.75 | N/A | N/A |
| Galidesivir | PA_INFA | Polymerase acidic protein | -6.88 | -6.57 | -6.86 | 30.81% | CHEMBL3944613 |
| Tenofovir | PA_INFA | Polymerase acidic protein | -6.44 | -5.53 | -6.28 | 26.88% | CHEMBL3944613 |
| Galidesivir | PA_INFB | Polymerase acidic protein | -6.61 | N/A | N/A | N/A | N/A |
| Tenofovir | PA_INFB | Polymerase acidic protein | -5.94 | N/A | N/A | N/A | N/A |
| Galidesivir | PB2_A-H3N2 | Polymerase basic protein 2 | -6.32 | -6.86 | N/A | N/A | N/A |
| Tenofovir | PB2_A-H3N2 | Polymerase basic protein 2 | -5.85 | -5.63 | N/A | N/A | N/A |
| Galidesivir | PB2_A-H5N1 | Polymerase basic protein 2 | -6.49 | -6.14 | -6.93 | N/A | N/A |
| Tenofovir | PB2_A-H5N1 | Polymerase basic protein 2 | -5.94 | -5.86 | -5.96 | N/A | N/A |
| Galidesivir | PB2_INFB | Polymerase basic protein 2 | -6.55 | N/A | N/A | N/A | N/A |
| Tenofovir | PB2_INFB | Polymerase basic protein 2 | -6.01 | N/A | N/A | N/A | N/A |
| Galidesivir | PB3_A-H3N2 | Polymerase basic protein 2 | -6.93 | N/A | N/A | N/A | N/A |
| Tenofovir | PB3_A-H3N2 | Polymerase basic protein 2 | -6.07 | N/A | N/A | N/A | N/A |
| Galidesivir | PB4_A-H3N2 | Polymerase basic protein 2 | -7.08 | N/A | N/A | N/A | N/A |
| Tenofovir | PB4_A-H3N2 | Polymerase basic protein 2 | -6.62 | N/A | N/A | N/A | N/A |
| Galidesivir | PLP_SARS | Replicase polyprotein 1a | -7.37 | -7.56 | -7.87 | 22.68% | CHEMBL358279 |
| Tenofovir | PLP_SARS | Replicase polyprotein 1a | -7.05 | -7.02 | -7.08 | 14.92% | CHEMBL213054 |
| Galidesivir | PLP_SARS2 | papain-like protease | -6.06 | N/A | N/A | N/A | N/A |
| Tenofovir | PLP_SARS2 | papain-like protease | -5.94 | N/A | N/A | N/A | N/A |
| Galidesivir | PM_9VIRU | RNA-directed RNA polymerase L | -6.88 | -7.05 | N/A | N/A | N/A |
| Tenofovir | PM_9VIRU | RNA-directed RNA polymerase L | -5.63 | -5.49 | N/A | N/A | N/A |
| Galidesivir | PR_FCoV | Replicase polyprotein 1ab | -6.47 | N/A | N/A | 25.73% | CHEMBL4214471 |
| Tenofovir | PR_FCoV | Replicase polyprotein 1ab | -6.26 | N/A | N/A | 13.92% | CHEMBL4214066 |
| Galidesivir | PR_HCoV-229E | Replicase polyprotein 1a | -6.35 | -6.29 | N/A | N/A | N/A |
| Tenofovir | PR_HCoV-229E | Replicase polyprotein 1a | -5.85 | -5.66 | N/A | N/A | N/A |
| Galidesivir | PR_HCoV-NL63 | Replicase polyprotein 1a | -4.58 | -6.93 | N/A | N/A | N/A |
| Tenofovir | PR_HCoV-NL63 | Replicase polyprotein 1a | -4.95 | -6.53 | N/A | N/A | N/A |
| Galidesivir | PR_HIV1 | Gag-Pol polyprotein | -5.95 | -6.52 | -6.25 | 26.58% | CHEMBL3645129 |
| Tenofovir | PR_HIV1 | Gag-Pol polyprotein | -5.31 | -5.76 | -5.92 | 15.79% | CHEMBL3645129 |
| Galidesivir | PR_HIV2 | Gag-Pol polyprotein | -6.49 | -6.02 | N/A | N/A | N/A |
| Tenofovir | PR_HIV2 | Gag-Pol polyprotein | -5.80 | -5.36 | N/A | N/A | N/A |
| Galidesivir | PR_HKU1 | Replicase polyprotein 1a | -6.68 | N/A | N/A | N/A | N/A |
| Tenofovir | PR_HKU1 | Replicase polyprotein 1a | -5.74 | N/A | N/A | N/A | N/A |
| Galidesivir | PR_HKU4 | Replicase polyprotein 1ab | -6.39 | -6.41 | -6.49 | N/A | N/A |
| Tenofovir | PR_HKU4 | Replicase polyprotein 1ab | -5.63 | -6.38 | -6.24 | N/A | N/A |
| Galidesivir | PR_IBV | Replicase polyprotein 1a | -6.61 | N/A | N/A | N/A | N/A |
| Tenofovir | PR_IBV | Replicase polyprotein 1a | -6.19 | N/A | N/A | N/A | N/A |
| Galidesivir | PR_MERs | 3C-like proteinase | -6.82 | -6.46 | N/A | N/A | N/A |
| Tenofovir | PR_MERs | 3C-like proteinase | -6.36 | -6.44 | N/A | N/A | N/A |
| Galidesivir | PR_PEDV | 3C-like proteinase | -6.36 | N/A | N/A | N/A | N/A |
| Tenofovir | PR_PEDV | 3C-like proteinase | -6.16 | N/A | N/A | N/A | N/A |
| Galidesivir | PR_SARS | Replicase polyprotein 1ab | -6.72 | -7.51 | -6.84 | 22.22% | CHEMBL2441741 |
| Tenofovir | PR_SARS | Replicase polyprotein 1ab | -6.10 | -6.09 | -6.20 | 14.04% | CHEMBL2441741 |
| Galidesivir | PR_SARS2 | 3C-like protease | -6.60 | N/A | N/A | N/A | N/A |
| Tenofovir | PR_SARS2 | 3C-like protease | -6.59 | N/A | N/A | N/A | N/A |
| Galidesivir | PR_TGEV | Replicase polyprotein 1a | -6.72 | N/A | N/A | N/A | N/A |
| Tenofovir | PR_TGEV | Replicase polyprotein 1a | -5.68 | N/A | N/A | N/A | N/A |
| Galidesivir | P_9CALI | Norovirus P domain protein | -7.19 | N/A | N/A | N/A | N/A |
| Tenofovir | P_9CALI | Norovirus P domain protein | -6.25 | N/A | N/A | N/A | N/A |
| Galidesivir | P_NVN68 | Capsid protein VP1 | -5.40 | N/A | N/A | N/A | N/A |
| Tenofovir | P_NVN68 | Capsid protein VP1 | -4.61 | N/A | N/A | N/A | N/A |
| Galidesivir | RDRP_SARS2 | RNA-dependent RNA polymerase | -6.64 | N/A | N/A | 29.00% | CHEMBL4065616 |
| Tenofovir | RDRP_SARS2 | RNA-dependent RNA polymerase | -6.17 | N/A | N/A | 19.59% | CHEMBL4065616 |
| Galidesivir | RT_HIV1 | Gag-Pol polyprotein | -7.69 | -7.91 | -7.45 | 32.97% | CHEMBL4108139 |
| Tenofovir | RT_HIV1 | Gag-Pol polyprotein | -7.20 | -7.33 | -6.61 | 23.84% | CHEMBL4288759 |
| Galidesivir | SPIKE_HCoV-229E | Spike glycoprotein | -4.51 | N/A | N/A | N/A | N/A |
| Tenofovir | SPIKE_HCoV-229E | Spike glycoprotein | -4.65 | N/A | N/A | N/A | N/A |
| Galidesivir | SPIKE_HCoV-NL63 | Spike glycoprotein | -5.41 | N/A | N/A | N/A | N/A |
| Tenofovir | SPIKE_HCoV-NL63 | Spike glycoprotein | -4.93 | N/A | N/A | N/A | N/A |
| Galidesivir | SPIKE_HCoV-OC43 | Spike glycoprotein | -6.53 | N/A | N/A | N/A | N/A |
| Tenofovir | SPIKE_HCoV-OC43 | Spike glycoprotein | -5.60 | N/A | N/A | N/A | N/A |
| Galidesivir | SPIKE_HKU4 | Spike glycoprotein | -6.72 | N/A | N/A | N/A | N/A |
| Tenofovir | SPIKE_HKU4 | Spike glycoprotein | -5.77 | N/A | N/A | N/A | N/A |
| Galidesivir | SPIKE_IBV | Spike glycoprotein | -5.76 | N/A | N/A | N/A | N/A |
| Tenofovir | SPIKE_IBV | Spike glycoprotein | -4.81 | N/A | N/A | N/A | N/A |
| Galidesivir | SPIKE_MERs | Spike glycoprotein | -6.40 | -6.14 | -4.66 | N/A | N/A |
| Tenofovir | SPIKE_MERs | Spike glycoprotein | -5.28 | -5.90 | -4.60 | N/A | N/A |
| Galidesivir | SPIKE_MHV | Spike glycoprotein | -6.14 | N/A | N/A | N/A | N/A |
| Tenofovir | SPIKE_MHV | Spike glycoprotein | -5.84 | N/A | N/A | N/A | N/A |
| Galidesivir | SPIKE_PDCoV | Spike protein | -5.46 | N/A | N/A | N/A | N/A |
| Tenofovir | SPIKE_PDCoV | Spike protein | -5.84 | N/A | N/A | N/A | N/A |
| Galidesivir | SPIKE_SARS | Spike glycoprotein | -5.69 | -6.55 | N/A | N/A | N/A |
| Tenofovir | SPIKE_SARS | Spike glycoprotein | -5.54 | -5.98 | N/A | N/A | N/A |
| Galidesivir | SPIKE_SARS2 | Spike glycoprotein | -5.10 | -5.98 | -5.42 | N/A | N/A |
| Tenofovir | SPIKE_SARS2 | Spike glycoprotein | -4.62 | -4.58 | -4.65 | N/A | N/A |
| Galidesivir | VP1_9CALI | Capsid protein | -7.66 | N/A | N/A | N/A | N/A |
| Tenofovir | VP1_9CALI | Capsid protein | -6.83 | N/A | N/A | N/A | N/A |
| Galidesivir | VP1_NVN68 | Capsid protein VP1 | -5.81 | N/A | N/A | N/A | N/A |
| Tenofovir | VP1_NVN68 | Capsid protein VP1 | -4.92 | N/A | N/A | N/A | N/A |
| Galidesivir | VP24_EBORE | Membrane-associated protein VP24 | -4.88 | N/A | N/A | N/A | N/A |
| Tenofovir | VP24_EBORE | Membrane-associated protein VP24 | -4.76 | N/A | N/A | N/A | N/A |
| Galidesivir | VP24_EBOSU | Membrane-associated protein VP24 | -4.70 | N/A | N/A | N/A | N/A |
| Tenofovir | VP24_EBOSU | Membrane-associated protein VP24 | -4.56 | N/A | N/A | N/A | N/A |
| Galidesivir | VP24_EBOZM | Membrane-associated protein VP24 | -4.95 | N/A | N/A | N/A | N/A |
| Tenofovir | VP24_EBOZM | Membrane-associated protein VP24 | -4.27 | N/A | N/A | N/A | N/A |
| Galidesivir | VP30_9MONO | Minor nucleoprotein VP30 | -5.08 | N/A | N/A | N/A | N/A |
| Tenofovir | VP30_9MONO | Minor nucleoprotein VP30 | -4.83 | N/A | N/A | N/A | N/A |
| Galidesivir | VP30_EBOZ5 | Transcriptional activator VP30 | -5.57 | N/A | N/A | N/A | N/A |
| Tenofovir | VP30_EBOZ5 | Transcriptional activator VP30 | -5.03 | N/A | N/A | N/A | N/A |
| Galidesivir | VP30_EBOZM | Transcriptional activator VP30 | -5.80 | N/A | N/A | N/A | N/A |
| Tenofovir | VP30_EBOZM | Transcriptional activator VP30 | -5.43 | N/A | N/A | N/A | N/A |
| Galidesivir | VP35_EBORR | Polymerase cofactor VP35 | -5.18 | N/A | N/A | N/A | N/A |
| Tenofovir | VP35_EBORR | Polymerase cofactor VP35 | -4.44 | N/A | N/A | N/A | N/A |
| Galidesivir | VP35_EBOZM | Polymerase cofactor VP35 | -5.41 | -5.61 | -5.41 | N/A | N/A |
| Tenofovir | VP35_EBOZM | Polymerase cofactor VP35 | -4.70 | -4.83 | -4.60 | N/A | N/A |
| Galidesivir | VP40_EBOZM | Matrix protein VP40 | -5.05 | -4.91 | N/A | N/A | N/A |
| Tenofovir | VP40_EBOZM | Matrix protein VP40 | -5.23 | -4.64 | N/A | N/A | N/A |