| Ligand | Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | ||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||||
| Saquinavir | GP160_HIV1 | Envelope glycoprotein gp160 | -8.07 | -8.88 | -8.89 | N/A | N/A |
| Bictegravir | GP160_HIV1 | Envelope glycoprotein gp160 | -8.02 | -8.18 | -7.38 | N/A | N/A |
| Telaprevir | GP160_HIV1 | Envelope glycoprotein gp160 | -6.94 | -6.58 | -7.08 | N/A | N/A |
| Saquinavir | GP160_HIV2 | Envelope glycoprotein gp160 | -7.19 | N/A | N/A | N/A | N/A |
| Bictegravir | GP160_HIV2 | Envelope glycoprotein gp160 | -8.60 | N/A | N/A | N/A | N/A |
| Telaprevir | GP160_HIV2 | Envelope glycoprotein gp160 | -7.40 | N/A | N/A | N/A | N/A |
| Saquinavir | GP_EBOV | Envelope glycoprotein | -8.64 | -8.49 | -8.55 | 45.82% | CHEMBL3125895 |
| Bictegravir | GP_EBOV | Envelope glycoprotein | -9.34 | -9.70 | -8.73 | 31.95% | CHEMBL3125895 |
| Telaprevir | GP_EBOV | Envelope glycoprotein | -8.12 | -8.13 | -7.91 | 31.23% | CHEMBL3125895 |
| Saquinavir | HA_A-H10N7 | Hemagglutinin | -7.37 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H10N7 | Hemagglutinin | -8.76 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H10N7 | Hemagglutinin | -7.75 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_A-H10N8 | Hemagglutinin | -7.07 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H10N8 | Hemagglutinin | -7.43 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H10N8 | Hemagglutinin | -6.90 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_A-H13N6 | Hemagglutinin | -6.07 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H13N6 | Hemagglutinin | -5.11 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H13N6 | Hemagglutinin | -6.80 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_A-H14N6 | Hemagglutinin | -8.34 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H14N6 | Hemagglutinin | -8.81 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H14N6 | Hemagglutinin | -6.96 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_A-H15N9 | Hemagglutinin | -7.39 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H15N9 | Hemagglutinin | -8.31 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H15N9 | Hemagglutinin | -6.64 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_A-H17N10 | Hemagglutinin | -6.18 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H17N10 | Hemagglutinin | -7.19 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H17N10 | Hemagglutinin | -7.11 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_A-H18N11 | Hemagglutinin | -7.45 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H18N11 | Hemagglutinin | -6.53 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H18N11 | Hemagglutinin | -5.86 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_A-H1N1 | Hemagglutinin | -7.39 | -7.48 | N/A | N/A | N/A |
| Bictegravir | HA_A-H1N1 | Hemagglutinin | -7.81 | -7.91 | N/A | N/A | N/A |
| Telaprevir | HA_A-H1N1 | Hemagglutinin | -7.75 | -6.93 | N/A | N/A | N/A |
| Saquinavir | HA_A-H2N2 | Hemagglutinin | -7.18 | -6.90 | N/A | N/A | N/A |
| Bictegravir | HA_A-H2N2 | Hemagglutinin | -7.84 | -7.01 | N/A | N/A | N/A |
| Telaprevir | HA_A-H2N2 | Hemagglutinin | -6.14 | -6.75 | N/A | N/A | N/A |
| Saquinavir | HA_A-H3N2 | Hemagglutinin | -6.76 | -7.30 | -6.56 | N/A | N/A |
| Bictegravir | HA_A-H3N2 | Hemagglutinin | -8.23 | -8.29 | -7.91 | N/A | N/A |
| Telaprevir | HA_A-H3N2 | Hemagglutinin | -6.19 | -6.48 | -6.70 | N/A | N/A |
| Saquinavir | HA_A-H3N8 | Hemagglutinin | -6.55 | -6.33 | -6.47 | N/A | N/A |
| Bictegravir | HA_A-H3N8 | Hemagglutinin | -7.32 | -7.63 | -7.35 | N/A | N/A |
| Telaprevir | HA_A-H3N8 | Hemagglutinin | -6.56 | -7.39 | -6.83 | N/A | N/A |
| Saquinavir | HA_A-H5N1 | Hemagglutinin | -6.62 | -7.29 | -7.12 | N/A | N/A |
| Bictegravir | HA_A-H5N1 | Hemagglutinin | -8.51 | -8.10 | -8.04 | N/A | N/A |
| Telaprevir | HA_A-H5N1 | Hemagglutinin | -6.41 | -7.03 | -7.20 | N/A | N/A |
| Saquinavir | HA_A-H5N3 | Hemagglutinin | -7.56 | -7.17 | N/A | N/A | N/A |
| Bictegravir | HA_A-H5N3 | Hemagglutinin | -7.27 | -8.05 | N/A | N/A | N/A |
| Telaprevir | HA_A-H5N3 | Hemagglutinin | -6.57 | -6.24 | N/A | N/A | N/A |
| Saquinavir | HA_A-H6N1 | Hemagglutinin | -7.07 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H6N1 | Hemagglutinin | -7.43 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H6N1 | Hemagglutinin | -6.90 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_A-H6N6 | Hemagglutinin | -7.69 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H6N6 | Hemagglutinin | -7.89 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H6N6 | Hemagglutinin | -7.36 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_A-H7N2 | Hemagglutinin | -5.57 | -6.40 | -7.21 | N/A | N/A |
| Bictegravir | HA_A-H7N2 | Hemagglutinin | -7.41 | -7.32 | -7.29 | N/A | N/A |
| Telaprevir | HA_A-H7N2 | Hemagglutinin | -6.78 | -6.31 | -6.68 | N/A | N/A |
| Saquinavir | HA_A-H7N7 | Hemagglutinin | -7.21 | -8.03 | N/A | N/A | N/A |
| Bictegravir | HA_A-H7N7 | Hemagglutinin | -7.31 | -8.91 | N/A | N/A | N/A |
| Telaprevir | HA_A-H7N7 | Hemagglutinin | -5.85 | -6.84 | N/A | N/A | N/A |
| Saquinavir | HA_A-H7N9 | Hemagglutinin | -7.24 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_A-H7N9 | Hemagglutinin | -7.74 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_A-H7N9 | Hemagglutinin | -6.63 | N/A | N/A | N/A | N/A |
| Saquinavir | HA_INFB | Hemagglutinin | -7.43 | -6.45 | N/A | N/A | N/A |
| Bictegravir | HA_INFB | Hemagglutinin | -7.97 | -8.24 | N/A | N/A | N/A |
| Telaprevir | HA_INFB | Hemagglutinin | -7.00 | -7.30 | N/A | N/A | N/A |
| Saquinavir | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | 44.42 | N/A | N/A | N/A | N/A |
| Bictegravir | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -5.24 | N/A | N/A | N/A | N/A |
| Telaprevir | HA_INFD | Hemagglutinin-esterase-fusion glycoprotein | -6.43 | N/A | N/A | N/A | N/A |
| Saquinavir | HE_BCV | Hemagglutinin-esterase | -7.07 | -7.09 | N/A | N/A | N/A |
| Bictegravir | HE_BCV | Hemagglutinin-esterase | -8.44 | -7.89 | N/A | N/A | N/A |
| Telaprevir | HE_BCV | Hemagglutinin-esterase | -8.32 | -7.22 | N/A | N/A | N/A |
| Saquinavir | HE_HCoV-OC43 | Hemagglutinin-esterase | -6.50 | N/A | N/A | N/A | N/A |
| Bictegravir | HE_HCoV-OC43 | Hemagglutinin-esterase | -7.02 | N/A | N/A | N/A | N/A |
| Telaprevir | HE_HCoV-OC43 | Hemagglutinin-esterase | -5.75 | N/A | N/A | N/A | N/A |
| Saquinavir | HE_MHV | Hemagglutinin-esterase | -6.84 | N/A | N/A | N/A | N/A |
| Bictegravir | HE_MHV | Hemagglutinin-esterase | -7.29 | N/A | N/A | N/A | N/A |
| Telaprevir | HE_MHV | Hemagglutinin-esterase | -6.15 | N/A | N/A | N/A | N/A |
| Saquinavir | IN_HIV1 | Gag-Pol polyprotein | -6.09 | -7.42 | N/A | N/A | N/A |
| Bictegravir | IN_HIV1 | Gag-Pol polyprotein | -6.27 | -6.94 | N/A | N/A | N/A |
| Telaprevir | IN_HIV1 | Gag-Pol polyprotein | -5.47 | -5.38 | N/A | N/A | N/A |
| Saquinavir | MD_HKU4 | Replicase polyprotein 1ab | -10.20 | -9.04 | -9.75 | N/A | N/A |
| Bictegravir | MD_HKU4 | Replicase polyprotein 1ab | -10.19 | -10.05 | -10.22 | N/A | N/A |
| Telaprevir | MD_HKU4 | Replicase polyprotein 1ab | -7.52 | -7.37 | -7.40 | N/A | N/A |
| Saquinavir | MD_MERs | Replicase polyprotein 1a | -10.42 | -10.00 | N/A | N/A | N/A |
| Bictegravir | MD_MERs | Replicase polyprotein 1a | -10.38 | -10.08 | N/A | N/A | N/A |
| Telaprevir | MD_MERs | Replicase polyprotein 1a | -8.15 | -9.35 | N/A | N/A | N/A |
| Saquinavir | MX2_A-H5N1 | Matrix protein 2 | 10.59 | N/A | N/A | N/A | N/A |
| Bictegravir | MX2_A-H5N1 | Matrix protein 2 | -9.98 | N/A | N/A | N/A | N/A |
| Telaprevir | MX2_A-H5N1 | Matrix protein 2 | 16.02 | N/A | N/A | N/A | N/A |
| Saquinavir | NA_A-H11N6 | Neuraminidase | -8.75 | -8.91 | -8.67 | N/A | N/A |
| Bictegravir | NA_A-H11N6 | Neuraminidase | -9.92 | -9.55 | -9.60 | N/A | N/A |
| Telaprevir | NA_A-H11N6 | Neuraminidase | -7.59 | -7.55 | -7.18 | N/A | N/A |
| Saquinavir | NA_A-H11N9 | Neuraminidase | -8.78 | -10.03 | -10.61 | N/A | N/A |
| Bictegravir | NA_A-H11N9 | Neuraminidase | -8.21 | -9.74 | -9.42 | N/A | N/A |
| Telaprevir | NA_A-H11N9 | Neuraminidase | -6.28 | -7.61 | -9.37 | N/A | N/A |
| Saquinavir | NA_A-H12N5 | Neuraminidase | -9.87 | -9.83 | -8.58 | N/A | N/A |
| Bictegravir | NA_A-H12N5 | Neuraminidase | -9.67 | -9.61 | -9.66 | N/A | N/A |
| Telaprevir | NA_A-H12N5 | Neuraminidase | -7.01 | -7.88 | -7.80 | N/A | N/A |
| Saquinavir | NA_A-H13N9 | Neuraminidase | -7.35 | N/A | N/A | N/A | N/A |
| Bictegravir | NA_A-H13N9 | Neuraminidase | -8.35 | N/A | N/A | N/A | N/A |
| Telaprevir | NA_A-H13N9 | Neuraminidase | -6.65 | N/A | N/A | N/A | N/A |
| Saquinavir | NA_A-H17N10 | Neuraminidase | -7.98 | N/A | N/A | N/A | N/A |
| Bictegravir | NA_A-H17N10 | Neuraminidase | -9.24 | N/A | N/A | N/A | N/A |
| Telaprevir | NA_A-H17N10 | Neuraminidase | -7.43 | N/A | N/A | N/A | N/A |
| Saquinavir | NA_A-H18N11 | Neuraminidase | -7.43 | N/A | N/A | N/A | N/A |
| Bictegravir | NA_A-H18N11 | Neuraminidase | -8.37 | N/A | N/A | N/A | N/A |
| Telaprevir | NA_A-H18N11 | Neuraminidase | -7.80 | N/A | N/A | N/A | N/A |
| Saquinavir | NA_A-H1N1 | Neuraminidase | -9.88 | N/A | N/A | N/A | N/A |
| Bictegravir | NA_A-H1N1 | Neuraminidase | -9.58 | N/A | N/A | N/A | N/A |
| Telaprevir | NA_A-H1N1 | Neuraminidase | -8.27 | N/A | N/A | N/A | N/A |
| Saquinavir | NA_A-H2N2 | Neuraminidase | -8.47 | -9.46 | -8.92 | N/A | N/A |
| Bictegravir | NA_A-H2N2 | Neuraminidase | -8.68 | -10.03 | -9.34 | N/A | N/A |
| Telaprevir | NA_A-H2N2 | Neuraminidase | -8.58 | -8.55 | -8.46 | N/A | N/A |
| Saquinavir | NA_A-H3N2 | Ig heavy chain Mem5 | -9.17 | -7.72 | N/A | N/A | N/A |
| Bictegravir | NA_A-H3N2 | Ig heavy chain Mem5 | -9.29 | -9.28 | N/A | N/A | N/A |
| Telaprevir | NA_A-H3N2 | Ig heavy chain Mem5 | -8.69 | -7.35 | N/A | N/A | N/A |
| Saquinavir | NA_A-H3N8 | Neuraminidase | -9.09 | -9.27 | -9.80 | N/A | N/A |
| Bictegravir | NA_A-H3N8 | Neuraminidase | -9.62 | -9.33 | -10.04 | N/A | N/A |
| Telaprevir | NA_A-H3N8 | Neuraminidase | -9.08 | -8.94 | -9.08 | N/A | N/A |
| Saquinavir | NA_A-H5N1 | Neuraminidase | -9.90 | N/A | N/A | N/A | N/A |
| Bictegravir | NA_A-H5N1 | Neuraminidase | -9.17 | N/A | N/A | N/A | N/A |
| Telaprevir | NA_A-H5N1 | Neuraminidase | -8.53 | N/A | N/A | N/A | N/A |
| Saquinavir | NA_A-H7N9 | Neuraminidase | -10.11 | -10.00 | -9.78 | N/A | N/A |
| Bictegravir | NA_A-H7N9 | Neuraminidase | -9.64 | -9.85 | -9.61 | N/A | N/A |
| Telaprevir | NA_A-H7N9 | Neuraminidase | -9.28 | -8.99 | -8.50 | N/A | N/A |
| Saquinavir | NA_INFB | Neuraminidase | -8.57 | -8.64 | N/A | 38.74% | CHEMBL362993 |
| Bictegravir | NA_INFB | Neuraminidase | -8.98 | -8.55 | N/A | 31.12% | CHEMBL4175983 |
| Telaprevir | NA_INFB | Neuraminidase | -7.78 | -7.36 | N/A | 42.76% | CHEMBL195288 |
| Saquinavir | NP_A-H1N1 | Nucleoprotein | -7.08 | -8.06 | -7.36 | N/A | N/A |
| Bictegravir | NP_A-H1N1 | Nucleoprotein | -7.87 | -8.34 | -8.75 | N/A | N/A |
| Telaprevir | NP_A-H1N1 | Nucleoprotein | -6.59 | -6.41 | -6.86 | N/A | N/A |
| Saquinavir | NP_A-H5N1 | Nucleoprotein | -7.51 | N/A | N/A | N/A | N/A |
| Bictegravir | NP_A-H5N1 | Nucleoprotein | -8.06 | N/A | N/A | N/A | N/A |
| Telaprevir | NP_A-H5N1 | Nucleoprotein | -6.88 | N/A | N/A | N/A | N/A |
| Saquinavir | NP_HCoV-NL63 | Nucleoprotein | -7.54 | N/A | N/A | N/A | N/A |
| Bictegravir | NP_HCoV-NL63 | Nucleoprotein | -9.22 | N/A | N/A | N/A | N/A |
| Telaprevir | NP_HCoV-NL63 | Nucleoprotein | -7.35 | N/A | N/A | N/A | N/A |
| Saquinavir | NP_HCoV-OC43 | Nucleoprotein | -9.41 | -7.91 | -8.06 | 27.27% | CHEMBL3233481 |
| Bictegravir | NP_HCoV-OC43 | Nucleoprotein | -11.95 | -8.90 | -8.08 | 15.54% | CHEMBL3233481 |
| Telaprevir | NP_HCoV-OC43 | Nucleoprotein | -8.01 | -6.74 | -7.42 | 17.33% | CHEMBL3233481 |
| Saquinavir | NP_INFB | Nucleoprotein | -6.72 | N/A | N/A | N/A | N/A |
| Bictegravir | NP_INFB | Nucleoprotein | -6.19 | N/A | N/A | N/A | N/A |
| Telaprevir | NP_INFB | Nucleoprotein | -5.94 | N/A | N/A | N/A | N/A |
| Saquinavir | NP_INFD | NP | -6.54 | N/A | N/A | N/A | N/A |
| Bictegravir | NP_INFD | NP | -6.76 | N/A | N/A | N/A | N/A |
| Telaprevir | NP_INFD | NP | -5.27 | N/A | N/A | N/A | N/A |
| Saquinavir | NP_SARS | Nucleoprotein | -8.15 | N/A | N/A | N/A | N/A |
| Bictegravir | NP_SARS | Nucleoprotein | -9.04 | N/A | N/A | N/A | N/A |
| Telaprevir | NP_SARS | Nucleoprotein | -7.54 | N/A | N/A | N/A | N/A |
| Saquinavir | NS3_HCV1A | Genome polyprotein | -8.26 | -6.77 | -7.22 | 54.12% | CHEMBL3645761 |
| Bictegravir | NS3_HCV1A | Genome polyprotein | -7.77 | -7.76 | -9.84 | 37.41% | CHEMBL3645743 |
| Telaprevir | NS3_HCV1A | Genome polyprotein | -6.90 | -6.30 | -7.67 | 67.11% | CHEMBL3645733 |
| Saquinavir | NS3_HCV1B | Genome polyprotein | -9.29 | -9.13 | -6.79 | 50.00% | CHEMBL3954962 |
| Bictegravir | NS3_HCV1B | Genome polyprotein | -10.06 | -10.79 | -7.31 | 35.82% | CHEMBL3954962 |
| Telaprevir | NS3_HCV1B | Genome polyprotein | -7.27 | -7.98 | -6.54 | 100.00% | CHEMBL231813 |
| Saquinavir | NS3_HCV3A | Genome polyprotein | -7.20 | -6.55 | -6.88 | N/A | N/A |
| Bictegravir | NS3_HCV3A | Genome polyprotein | -9.34 | -9.04 | -7.87 | N/A | N/A |
| Telaprevir | NS3_HCV3A | Genome polyprotein | -8.12 | -7.60 | -7.42 | N/A | N/A |
| Saquinavir | NS5B_HCV1A | Genome polyprotein | -9.35 | -10.52 | -9.48 | 53.22% | CHEMBL13256 |
| Bictegravir | NS5B_HCV1A | Genome polyprotein | -10.61 | -9.96 | -10.18 | 36.11% | CHEMBL3644880 |
| Telaprevir | NS5B_HCV1A | Genome polyprotein | -8.94 | -8.92 | -8.81 | 88.43% | CHEMBL13256 |
| Saquinavir | NS5B_HCV1B | Genome polyprotein | -9.45 | -9.30 | -8.99 | 40.47% | CHEMBL3645202 |
| Bictegravir | NS5B_HCV1B | Genome polyprotein | -9.58 | -9.62 | -8.92 | 36.31% | CHEMBL3645214 |
| Telaprevir | NS5B_HCV1B | Genome polyprotein | -9.60 | -7.70 | -8.33 | 29.25% | CHEMBL3645202 |
| Saquinavir | NS5B_HCV2A | Genome polyprotein | -11.35 | -9.51 | N/A | N/A | N/A |
| Bictegravir | NS5B_HCV2A | Genome polyprotein | -11.00 | -10.69 | N/A | N/A | N/A |
| Telaprevir | NS5B_HCV2A | Genome polyprotein | -8.15 | -5.42 | N/A | N/A | N/A |
| Saquinavir | NSP15_SARS | Replicase polyprotein 1ab | -3.59 | N/A | N/A | 47.25% | CHEMBL2441745 |
| Bictegravir | NSP15_SARS | Replicase polyprotein 1ab | -8.04 | N/A | N/A | 24.29% | CHEMBL2441745 |
| Telaprevir | NSP15_SARS | Replicase polyprotein 1ab | -0.92 | N/A | N/A | 39.29% | CHEMBL2441745 |
| Saquinavir | NSP1_INFB | Non-structural protein 1 | -6.21 | -6.97 | N/A | N/A | N/A |
| Bictegravir | NSP1_INFB | Non-structural protein 1 | -7.15 | -7.45 | N/A | N/A | N/A |
| Telaprevir | NSP1_INFB | Non-structural protein 1 | -6.96 | -6.86 | N/A | N/A | N/A |
| Saquinavir | NSP1_SARS | Replicase polyprotein 1ab | -7.29 | N/A | N/A | 47.25% | CHEMBL2441745 |
| Bictegravir | NSP1_SARS | Replicase polyprotein 1ab | -7.95 | N/A | N/A | 24.29% | CHEMBL2441745 |
| Telaprevir | NSP1_SARS | Replicase polyprotein 1ab | -5.62 | N/A | N/A | 39.29% | CHEMBL2441745 |
| Saquinavir | NSP3_HCoV-229E | Replicase polyprotein 1a | -10.99 | N/A | N/A | N/A | N/A |
| Bictegravir | NSP3_HCoV-229E | Replicase polyprotein 1a | -11.83 | N/A | N/A | N/A | N/A |
| Telaprevir | NSP3_HCoV-229E | Replicase polyprotein 1a | -8.66 | N/A | N/A | N/A | N/A |
| Saquinavir | NSP3_IBV | Replicase polyprotein 1a | -9.25 | N/A | N/A | N/A | N/A |
| Bictegravir | NSP3_IBV | Replicase polyprotein 1a | -10.98 | N/A | N/A | N/A | N/A |
| Telaprevir | NSP3_IBV | Replicase polyprotein 1a | -8.31 | N/A | N/A | N/A | N/A |
| Saquinavir | NSP3_MHV | Replicase polyprotein 1ab | 33.98 | N/A | N/A | N/A | N/A |
| Bictegravir | NSP3_MHV | Replicase polyprotein 1ab | -5.99 | N/A | N/A | N/A | N/A |
| Telaprevir | NSP3_MHV | Replicase polyprotein 1ab | -7.58 | N/A | N/A | N/A | N/A |
| Saquinavir | NSP9_HCoV-229E | Replicase polyprotein 1ab | -7.05 | -6.83 | N/A | N/A | N/A |
| Bictegravir | NSP9_HCoV-229E | Replicase polyprotein 1ab | -7.93 | -8.26 | N/A | N/A | N/A |
| Telaprevir | NSP9_HCoV-229E | Replicase polyprotein 1ab | -6.55 | -6.77 | N/A | N/A | N/A |
| Saquinavir | PA_A-H17N10 | Polymerase acidic protein | -7.90 | N/A | N/A | N/A | N/A |
| Bictegravir | PA_A-H17N10 | Polymerase acidic protein | -9.52 | N/A | N/A | N/A | N/A |
| Telaprevir | PA_A-H17N10 | Polymerase acidic protein | -8.18 | N/A | N/A | N/A | N/A |
| Saquinavir | PA_A-H1N1 | Polymerase acidic protein | -10.93 | -9.72 | -9.35 | N/A | N/A |
| Bictegravir | PA_A-H1N1 | Polymerase acidic protein | -10.75 | -9.31 | -10.06 | N/A | N/A |
| Telaprevir | PA_A-H1N1 | Polymerase acidic protein | -8.36 | -9.11 | -8.43 | N/A | N/A |
| Saquinavir | PA_A-H5N1 | Polymerase acidic protein | -9.73 | -9.86 | -9.93 | N/A | N/A |
| Bictegravir | PA_A-H5N1 | Polymerase acidic protein | -10.31 | -10.27 | -10.01 | N/A | N/A |
| Telaprevir | PA_A-H5N1 | Polymerase acidic protein | -9.83 | -9.02 | -9.44 | N/A | N/A |
| Saquinavir | PA_INFA | Polymerase acidic protein | -9.22 | -8.55 | -9.56 | 35.43% | CHEMBL463590 |
| Bictegravir | PA_INFA | Polymerase acidic protein | -11.03 | -9.40 | -9.72 | 30.00% | CHEMBL2040578 |
| Telaprevir | PA_INFA | Polymerase acidic protein | -7.87 | -7.62 | -8.59 | 31.63% | CHEMBL2040569 |
| Saquinavir | PA_INFB | Polymerase acidic protein | -9.27 | N/A | N/A | N/A | N/A |
| Bictegravir | PA_INFB | Polymerase acidic protein | -9.27 | N/A | N/A | N/A | N/A |
| Telaprevir | PA_INFB | Polymerase acidic protein | -7.63 | N/A | N/A | N/A | N/A |
| Saquinavir | PB2_A-H3N2 | Polymerase basic protein 2 | -9.77 | -8.06 | N/A | N/A | N/A |
| Bictegravir | PB2_A-H3N2 | Polymerase basic protein 2 | -9.42 | -10.01 | N/A | N/A | N/A |
| Telaprevir | PB2_A-H3N2 | Polymerase basic protein 2 | -7.83 | -7.75 | N/A | N/A | N/A |
| Saquinavir | PB2_A-H5N1 | Polymerase basic protein 2 | -8.29 | -7.95 | -8.58 | N/A | N/A |
| Bictegravir | PB2_A-H5N1 | Polymerase basic protein 2 | -7.99 | -9.45 | -9.20 | N/A | N/A |
| Telaprevir | PB2_A-H5N1 | Polymerase basic protein 2 | -6.57 | -7.78 | -7.13 | N/A | N/A |
| Saquinavir | PB2_INFB | Polymerase basic protein 2 | -8.43 | N/A | N/A | N/A | N/A |
| Bictegravir | PB2_INFB | Polymerase basic protein 2 | -9.64 | N/A | N/A | N/A | N/A |
| Telaprevir | PB2_INFB | Polymerase basic protein 2 | -7.80 | N/A | N/A | N/A | N/A |
| Saquinavir | PB3_A-H3N2 | Polymerase basic protein 2 | -8.17 | N/A | N/A | N/A | N/A |
| Bictegravir | PB3_A-H3N2 | Polymerase basic protein 2 | -8.72 | N/A | N/A | N/A | N/A |
| Telaprevir | PB3_A-H3N2 | Polymerase basic protein 2 | -6.95 | N/A | N/A | N/A | N/A |
| Saquinavir | PB4_A-H3N2 | Polymerase basic protein 2 | -9.38 | N/A | N/A | N/A | N/A |
| Bictegravir | PB4_A-H3N2 | Polymerase basic protein 2 | -9.98 | N/A | N/A | N/A | N/A |
| Telaprevir | PB4_A-H3N2 | Polymerase basic protein 2 | -8.10 | N/A | N/A | N/A | N/A |
| Saquinavir | PLP_SARS | Replicase polyprotein 1a | -9.13 | -11.03 | -11.05 | 36.79% | CHEMBL213054 |
| Bictegravir | PLP_SARS | Replicase polyprotein 1a | -10.77 | -10.34 | -10.68 | 29.32% | CHEMBL213054 |
| Telaprevir | PLP_SARS | Replicase polyprotein 1a | -8.89 | -8.92 | -8.71 | 34.50% | CHEMBL213054 |
| Saquinavir | PR_FCoV | Replicase polyprotein 1ab | -8.42 | N/A | N/A | N/A | N/A |
| Bictegravir | PR_FCoV | Replicase polyprotein 1ab | -9.64 | N/A | N/A | N/A | N/A |
| Telaprevir | PR_FCoV | Replicase polyprotein 1ab | -8.03 | N/A | N/A | N/A | N/A |
| Saquinavir | PR_HCoV-229E | Replicase polyprotein 1a | -8.25 | -8.09 | N/A | N/A | N/A |
| Bictegravir | PR_HCoV-229E | Replicase polyprotein 1a | -9.47 | -8.63 | N/A | N/A | N/A |
| Telaprevir | PR_HCoV-229E | Replicase polyprotein 1a | -7.42 | -7.75 | N/A | N/A | N/A |
| Saquinavir | PR_HCoV-NL63 | Replicase polyprotein 1a | -5.49 | -8.90 | N/A | N/A | N/A |
| Bictegravir | PR_HCoV-NL63 | Replicase polyprotein 1a | -5.32 | -9.41 | N/A | N/A | N/A |
| Telaprevir | PR_HCoV-NL63 | Replicase polyprotein 1a | -5.51 | -8.44 | N/A | N/A | N/A |
| Saquinavir | PR_HIV1 | Gag-Pol polyprotein | -7.62 | -7.95 | -7.93 | 31.65% | CHEMBL492666 |
| Bictegravir | PR_HIV1 | Gag-Pol polyprotein | -8.39 | -8.43 | -7.97 | 25.83% | CHEMBL3645128 |
| Telaprevir | PR_HIV1 | Gag-Pol polyprotein | -7.12 | -7.03 | -7.24 | 20.48% | CHEMBL492666 |
| Saquinavir | PR_HIV2 | Gag-Pol polyprotein | -7.61 | -8.12 | N/A | N/A | N/A |
| Bictegravir | PR_HIV2 | Gag-Pol polyprotein | -8.90 | -8.45 | N/A | N/A | N/A |
| Telaprevir | PR_HIV2 | Gag-Pol polyprotein | -7.57 | -7.31 | N/A | N/A | N/A |
| Saquinavir | PR_HKU1 | Replicase polyprotein 1a | -8.80 | N/A | N/A | N/A | N/A |
| Bictegravir | PR_HKU1 | Replicase polyprotein 1a | -8.52 | N/A | N/A | N/A | N/A |
| Telaprevir | PR_HKU1 | Replicase polyprotein 1a | -6.96 | N/A | N/A | N/A | N/A |
| Saquinavir | PR_HKU4 | Replicase polyprotein 1ab | -8.57 | -9.37 | -8.03 | N/A | N/A |
| Bictegravir | PR_HKU4 | Replicase polyprotein 1ab | -8.88 | -8.73 | -8.59 | N/A | N/A |
| Telaprevir | PR_HKU4 | Replicase polyprotein 1ab | -6.52 | -7.04 | -7.12 | N/A | N/A |
| Saquinavir | PR_IBV | Replicase polyprotein 1a | -9.03 | N/A | N/A | N/A | N/A |
| Bictegravir | PR_IBV | Replicase polyprotein 1a | -9.50 | N/A | N/A | N/A | N/A |
| Telaprevir | PR_IBV | Replicase polyprotein 1a | -7.85 | N/A | N/A | N/A | N/A |
| Saquinavir | PR_MERs | 3C-like proteinase | -9.43 | -9.12 | N/A | N/A | N/A |
| Bictegravir | PR_MERs | 3C-like proteinase | -8.92 | -9.59 | N/A | N/A | N/A |
| Telaprevir | PR_MERs | 3C-like proteinase | -7.77 | -8.16 | N/A | N/A | N/A |
| Saquinavir | PR_PEDV | 3C-like proteinase | -8.36 | N/A | N/A | N/A | N/A |
| Bictegravir | PR_PEDV | 3C-like proteinase | -9.08 | N/A | N/A | N/A | N/A |
| Telaprevir | PR_PEDV | 3C-like proteinase | -7.54 | N/A | N/A | N/A | N/A |
| Saquinavir | PR_SARS | Replicase polyprotein 1ab | -8.83 | -9.25 | -8.27 | 47.25% | CHEMBL2441745 |
| Bictegravir | PR_SARS | Replicase polyprotein 1ab | -9.79 | -8.65 | -8.88 | 24.29% | CHEMBL2441745 |
| Telaprevir | PR_SARS | Replicase polyprotein 1ab | -7.02 | -6.61 | -7.63 | 39.29% | CHEMBL2441745 |
| Saquinavir | PR_SARS2 | 3C-like protease | -9.04 | N/A | N/A | N/A | N/A |
| Bictegravir | PR_SARS2 | 3C-like protease | -9.47 | N/A | N/A | N/A | N/A |
| Telaprevir | PR_SARS2 | 3C-like protease | -7.88 | N/A | N/A | N/A | N/A |
| Saquinavir | PR_TGEV | Replicase polyprotein 1a | -8.18 | N/A | N/A | N/A | N/A |
| Bictegravir | PR_TGEV | Replicase polyprotein 1a | -8.53 | N/A | N/A | N/A | N/A |
| Telaprevir | PR_TGEV | Replicase polyprotein 1a | -7.06 | N/A | N/A | N/A | N/A |
| Saquinavir | RT_HIV1 | Gag-Pol polyprotein | -9.93 | -10.18 | -9.54 | 41.94% | CHEMBL4227326 |
| Bictegravir | RT_HIV1 | Gag-Pol polyprotein | -11.02 | -11.90 | -10.85 | 30.95% | CHEMBL4109767 |
| Telaprevir | RT_HIV1 | Gag-Pol polyprotein | -9.22 | -9.13 | -8.55 | 31.17% | CHEMBL3921297 |
| Saquinavir | SPIKE_HCoV-229E | Spike glycoprotein | -5.15 | N/A | N/A | N/A | N/A |
| Bictegravir | SPIKE_HCoV-229E | Spike glycoprotein | -6.23 | N/A | N/A | N/A | N/A |
| Telaprevir | SPIKE_HCoV-229E | Spike glycoprotein | -5.11 | N/A | N/A | N/A | N/A |
| Saquinavir | SPIKE_HCoV-NL63 | Spike glycoprotein | -6.53 | N/A | N/A | N/A | N/A |
| Bictegravir | SPIKE_HCoV-NL63 | Spike glycoprotein | -7.50 | N/A | N/A | N/A | N/A |
| Telaprevir | SPIKE_HCoV-NL63 | Spike glycoprotein | -5.48 | N/A | N/A | N/A | N/A |
| Saquinavir | SPIKE_HCoV-OC43 | Spike glycoprotein | -7.41 | N/A | N/A | N/A | N/A |
| Bictegravir | SPIKE_HCoV-OC43 | Spike glycoprotein | -7.77 | N/A | N/A | N/A | N/A |
| Telaprevir | SPIKE_HCoV-OC43 | Spike glycoprotein | -7.04 | N/A | N/A | N/A | N/A |
| Saquinavir | SPIKE_HKU4 | Spike glycoprotein | -7.23 | N/A | N/A | N/A | N/A |
| Bictegravir | SPIKE_HKU4 | Spike glycoprotein | -8.33 | N/A | N/A | N/A | N/A |
| Telaprevir | SPIKE_HKU4 | Spike glycoprotein | -6.87 | N/A | N/A | N/A | N/A |
| Saquinavir | SPIKE_IBV | Spike glycoprotein | -6.26 | N/A | N/A | N/A | N/A |
| Bictegravir | SPIKE_IBV | Spike glycoprotein | -7.76 | N/A | N/A | N/A | N/A |
| Telaprevir | SPIKE_IBV | Spike glycoprotein | -6.54 | N/A | N/A | N/A | N/A |
| Saquinavir | SPIKE_MERs | Spike glycoprotein | -7.70 | -7.10 | -6.48 | N/A | N/A |
| Bictegravir | SPIKE_MERs | Spike glycoprotein | -8.52 | -7.63 | -7.41 | N/A | N/A |
| Telaprevir | SPIKE_MERs | Spike glycoprotein | -6.19 | -6.03 | -5.81 | N/A | N/A |
| Saquinavir | SPIKE_MHV | Spike glycoprotein | -6.74 | N/A | N/A | N/A | N/A |
| Bictegravir | SPIKE_MHV | Spike glycoprotein | -8.99 | N/A | N/A | N/A | N/A |
| Telaprevir | SPIKE_MHV | Spike glycoprotein | -7.70 | N/A | N/A | N/A | N/A |
| Saquinavir | SPIKE_PDCoV | Spike protein | -6.48 | N/A | N/A | N/A | N/A |
| Bictegravir | SPIKE_PDCoV | Spike protein | -8.15 | N/A | N/A | N/A | N/A |
| Telaprevir | SPIKE_PDCoV | Spike protein | -7.47 | N/A | N/A | N/A | N/A |
| Saquinavir | SPIKE_SARS | Spike glycoprotein | -6.33 | -6.25 | N/A | N/A | N/A |
| Bictegravir | SPIKE_SARS | Spike glycoprotein | -7.85 | -7.69 | N/A | N/A | N/A |
| Telaprevir | SPIKE_SARS | Spike glycoprotein | -6.35 | -5.92 | N/A | N/A | N/A |
| Saquinavir | SPIKE_SARS2 | Spike glycoprotein | -5.73 | N/A | N/A | N/A | N/A |
| Bictegravir | SPIKE_SARS2 | Spike glycoprotein | -7.23 | N/A | N/A | N/A | N/A |
| Telaprevir | SPIKE_SARS2 | Spike glycoprotein | -6.01 | N/A | N/A | N/A | N/A |