| Protein Symbol | Approved Name | Docking Scores |
Similarity Score |
Best Match | Prediction | |||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Result | Confidence Level | ||||
| 5HT1A_HUMAN | 5-hydroxytryptamine receptor 1A | -10.49 | -8.81 | -10.61 | 39.64% | CHEMBL1088072 | Active | 67.25% |
| 5HT1B_HUMAN | 5-hydroxytryptamine receptor 1B | -11.20 | -11.15 | -10.56 | 36.36% | CHEMBL159381 | N/A | N/A |
| 5HT1D_HUMAN | 5-hydroxytryptamine receptor 1D | -10.50 | -10.14 | -10.84 | 36.36% | CHEMBL348304 | N/A | N/A |
| 5HT1E_HUMAN | 5-hydroxytryptamine receptor 1E | -11.30 | -9.68 | -10.01 | 24.42% | CHEMBL103479 | Active | 57.48% |
| 5HT1F_HUMAN | 5-hydroxytryptamine receptor 1F | -9.85 | -11.74 | -11.21 | 26.92% | CHEMBL320198 | Inactive | 63.72% |
| 5HT2A_HUMAN | 5-hydroxytryptamine receptor 2A | -10.52 | -12.06 | N/A | 41.62% | CHEMBL328662 | N/A | N/A |
| 5HT2B_HUMAN | 5-hydroxytryptamine receptor 2B | -11.36 | -10.94 | -11.31 | 38.56% | CHEMBL422931 | N/A | N/A |
| 5HT2C_HUMAN | 5-hydroxytryptamine receptor 2C | -10.88 | -10.70 | N/A | 41.62% | CHEMBL328662 | N/A | N/A |
| 5HT4R_HUMAN | 5-hydroxytryptamine receptor 4 | -10.92 | -10.65 | -10.69 | 34.74% | CHEMBL3741508 | Inactive | 77.88% |
| 5HT5A_HUMAN | 5-hydroxytryptamine receptor 5A | -11.28 | -8.39 | -8.81 | 28.72% | CHEMBL403102 | Inactive | 83.97% |
| 5HT6R_HUMAN | 5-hydroxytryptamine receptor 6 | -9.52 | -9.63 | -9.71 | 29.86% | CHEMBL900 | Active | 54.78% |
| 5HT7R_HUMAN | 5-hydroxytryptamine receptor 7 | -11.87 | -10.33 | -10.53 | 36.78% | CHEMBL329566 | Inactive | 55.91% |
| AA1R_HUMAN | adenosine A1 receptor | -10.24 | -10.53 | -8.31 | 34.09% | CHEMBL3763434 | N/A | N/A |
| AA2AR_HUMAN | adenosine A2a receptor | -9.84 | -10.08 | -10.89 | 36.10% | CHEMBL3911977 | N/A | N/A |
| AA2BR_HUMAN | adenosine A2b receptor | -10.67 | -10.82 | -9.95 | 28.33% | CHEMBL202828 | Inactive | 74.64% |
| AA3R_HUMAN | adenosine A3 receptor | -6.00 | -1.48 | -6.13 | 35.33% | CHEMBL197027 | Inactive | 99.99% |
| ACM1_HUMAN | cholinergic receptor muscarinic 1 | -9.35 | 8.75 | N/A | 34.38% | CHEMBL2110892 | N/A | N/A |
| ACM2_HUMAN | cholinergic receptor muscarinic 2 | -10.96 | -10.18 | -9.00 | 37.85% | CHEMBL51096 | Active | 56.39% |
| ACM3_HUMAN | cholinergic receptor muscarinic 3 | -10.63 | -10.96 | -10.72 | 40.36% | CHEMBL1921938 | Active | 64.47% |
| ACM4_HUMAN | cholinergic receptor muscarinic 4 | -9.84 | -8.34 | N/A | 34.81% | CHEMBL292857 | N/A | N/A |
| ACM5_HUMAN | cholinergic receptor muscarinic 5 | -11.50 | -12.29 | -11.31 | 34.19% | CHEMBL2042554 | Active | 88.48% |
| ACTHR_HUMAN | melanocortin 2 receptor | -11.41 | -10.83 | -11.25 | N/A | N/A | N/A | N/A |
| ADA1D_HUMAN | adrenoceptor alpha 1D | -10.36 | -9.96 | -8.74 | 39.64% | CHEMBL1088072 | Active | 61.77% |
| ADA2A_HUMAN | adrenoceptor alpha 2A | -0.49 | -0.70 | 2.39 | 36.78% | CHEMBL329566 | Inactive | 99.99% |
| ADA2B_HUMAN | adrenoceptor alpha 2B | -10.61 | -10.84 | -9.05 | 31.58% | CHEMBL60889 | Inactive | 65.27% |
| ADA2C_HUMAN | adrenoceptor alpha 2C | 0.70 | 2.96 | 2.46 | 36.78% | CHEMBL329566 | Inactive | 99.99% |
| ADRB1_HUMAN | adrenoceptor beta 1 | -11.35 | -10.09 | -9.84 | 30.06% | CHEMBL1084891 | Active | 68.20% |
| ADRB2_HUMAN | adrenoceptor beta 2 | -8.70 | -9.15 | -11.02 | 33.50% | CHEMBL235612 | N/A | N/A |
| ADRB3_HUMAN | adrenoceptor beta 3 | -12.15 | -10.31 | -10.89 | 42.33% | CHEMBL4087670 | N/A | N/A |
| AGTR2_HUMAN | angiotensin II receptor type 2 | -11.71 | -11.57 | -12.11 | 27.80% | CHEMBL444065 | N/A | N/A |
| BKRB2_HUMAN | bradykinin receptor B2 | -11.42 | -10.77 | -11.39 | 27.78% | CHEMBL559506 | Inactive | 59.17% |
| CALCR_HUMAN | calcitonin receptor | -8.00 | -8.72 | -9.53 | 19.92% | CHEMBL2369907 | Inactive | 97.54% |
| CCKAR_HUMAN | cholecystokinin A receptor | -10.25 | -8.81 | -9.59 | 27.80% | CHEMBL250974 | Inactive | 69.24% |
| CCR1_HUMAN | C-C motif chemokine receptor 1 | -9.94 | -9.72 | -9.94 | 33.33% | CHEMBL254316 | Inactive | 51.64% |
| CCR2_HUMAN | C-C motif chemokine receptor 2 | -9.92 | -9.28 | -8.65 | 40.11% | CHEMBL3589845 | Active | 53.79% |
| CCR4_HUMAN | C-C motif chemokine receptor 4 | -9.11 | -8.77 | -7.84 | 34.68% | CHEMBL1907216 | Inactive | 63.88% |
| CCR5_HUMAN | C-C motif chemokine receptor 5 | -9.59 | -10.21 | -9.22 | 39.22% | CHEMBL1077353 | Inactive | 57.46% |
| CLTR1_HUMAN | cysteinyl leukotriene receptor 1 | -10.42 | -10.74 | -11.70 | 29.44% | CHEMBL419796 | Active | 56.23% |
| CNR1_HUMAN | cannabinoid receptor 1 | -8.44 | -10.64 | -11.37 | 35.48% | CHEMBL274983 | N/A | N/A |
| CNR2_HUMAN | cannabinoid receptor 2 | -10.91 | -11.95 | N/A | 40.20% | CHEMBL1760931 | N/A | N/A |
| CXCR1_HUMAN | C-X-C motif chemokine receptor 1 | -1.99 | N/A | N/A | 27.54% | CHEMBL3609018 | N/A | N/A |
| CXCR2_HUMAN | C-X-C motif chemokine receptor 2 | -9.87 | -9.72 | -8.91 | 30.45% | CHEMBL3980279 | Inactive | 72.55% |
| CXCR3_HUMAN | C-X-C motif chemokine receptor 3 | -11.19 | -11.14 | -10.70 | 38.43% | CHEMBL230453 | Active | 69.90% |
| CXCR4_HUMAN | C-X-C motif chemokine receptor 4 | -11.03 | -8.30 | -8.75 | 33.55% | CHEMBL3948266 | N/A | N/A |
| DRD1_HUMAN | dopamine receptor D1 | -9.97 | -10.82 | -10.04 | 36.78% | CHEMBL329566 | Active | 50.53% |
| DRD2_HUMAN | dopamine receptor D2 | -10.04 | N/A | N/A | 38.46% | CHEMBL109299 | N/A | N/A |
| DRD3_HUMAN | dopamine receptor D3 | -9.49 | N/A | N/A | 38.46% | CHEMBL109299 | N/A | N/A |
| DRD4_HUMAN | dopamine receptor D4 | -12.13 | -12.31 | N/A | 38.56% | CHEMBL3335543 | N/A | N/A |
| DRD5_HUMAN | dopamine receptor D5 | -11.24 | -10.78 | -10.24 | 26.23% | CHEMBL116463 | Active | 79.56% |
| EDNRA_HUMAN | endothelin receptor type A | -9.72 | -9.11 | -8.46 | 36.32% | CHEMBL96614 | Inactive | 58.12% |
| GABR1_HUMAN | gamma-aminobutyric acid type B receptor subunit 1 | 8.52 | -2.53 | 23.30 | 22.28% | CHEMBL2391908 | Inactive | 99.99% |
| GASR_HUMAN | cholecystokinin B receptor | -10.11 | -7.95 | -7.54 | 35.56% | CHEMBL50986 | Inactive | 60.65% |
| GRM1_HUMAN | glutamate metabotropic receptor 1 | -10.60 | -8.44 | -8.82 | 33.33% | CHEMBL233708 | Inactive | 64.94% |
| GRM2_HUMAN | glutamate metabotropic receptor 2 | 3.93 | 6.30 | 6.05 | 35.12% | CHEMBL4092105 | Inactive | 99.99% |
| GRM3_HUMAN | glutamate metabotropic receptor 3 | -1.70 | -4.17 | -2.72 | 28.98% | CHEMBL3927108 | Inactive | 99.99% |
| GRM4_HUMAN | glutamate metabotropic receptor 4 | 2.63 | 1.98 | 1.53 | 26.26% | CHEMBL3609737 | Inactive | 99.99% |
| GRM5_HUMAN | glutamate metabotropic receptor 5 | -5.30 | -4.63 | -4.15 | 35.45% | CHEMBL3922815 | N/A | N/A |
| GRM6_HUMAN | glutamate metabotropic receptor 6 | -0.26 | -6.53 | -2.18 | 19.57% | CHEMBL1585091 | Inactive | 99.99% |
| GRM7_HUMAN | glutamate metabotropic receptor 7 | 0.65 | 3.59 | 1.89 | 24.42% | CHEMBL3560922 | Inactive | 99.99% |
| GRM8_HUMAN | glutamate metabotropic receptor 8 | 4.52 | 2.83 | 3.98 | 24.42% | CHEMBL3560922 | Inactive | 99.99% |
| HRH1_HUMAN | histamine receptor H1 | -7.19 | N/A | N/A | 41.62% | CHEMBL328662 | N/A | N/A |
| HRH2_HUMAN | histamine receptor H2 | -10.91 | -10.17 | -10.00 | 38.56% | CHEMBL422931 | Active | 98.08% |
| HRH3_HUMAN | histamine receptor H3 | -9.58 | -10.23 | -11.02 | 36.02% | CHEMBL571006 | Inactive | 54.19% |
| HRH4_HUMAN | histamine receptor H4 | -9.55 | -7.44 | -9.02 | 29.41% | CHEMBL1938971 | Inactive | 72.91% |
| MC3R_HUMAN | melanocortin 3 receptor | -11.33 | -10.89 | -9.48 | 34.48% | CHEMBL380437 | Inactive | 55.09% |
| MC4R_HUMAN | melanocortin 4 receptor | -8.63 | -8.18 | -8.45 | 37.80% | CHEMBL214988 | Inactive | 78.83% |
| MC5R_HUMAN | melanocortin 5 receptor | -8.18 | -10.59 | -6.49 | 32.99% | CHEMBL3890450 | Inactive | 95.69% |
| MSHR_HUMAN | melanocortin 1 receptor | -10.12 | -9.80 | -9.89 | 34.48% | CHEMBL380437 | Inactive | 56.82% |
| NK1R_HUMAN | tachykinin receptor 1 | -11.57 | -11.71 | -12.56 | 100.00% | CHEMBL1471 | N/A | N/A |
| NK2R_HUMAN | tachykinin receptor 2 | -9.34 | -9.82 | -9.86 | 94.07% | CHEMBL52330 | Active | 99.61% |
| NPBW1_HUMAN | neuropeptides B and W receptor 1 | -10.36 | -10.10 | -9.72 | 23.28% | CHEMBL1940539 | Inactive | 70.13% |
| NPFF1_HUMAN | neuropeptide FF receptor 1 | -9.52 | -9.68 | -9.72 | 24.28% | CHEMBL472833 | Inactive | 75.72% |
| NPSR1_HUMAN | neuropeptide S receptor 1 | -10.67 | -10.72 | -10.89 | 27.91% | CHEMBL469695 | Active | 75.75% |
| NPY1R_HUMAN | neuropeptide Y receptor Y1 | -10.38 | -10.25 | -10.24 | 27.49% | CHEMBL2046863 | N/A | N/A |
| NPY2R_HUMAN | neuropeptide Y receptor Y2 | -9.52 | -10.33 | -10.26 | 30.57% | CHEMBL3104179 | Inactive | 69.30% |
| NPY4R_HUMAN | neuropeptide Y receptor Y4 | -10.64 | -11.11 | -10.01 | 26.24% | CHEMBL2440912 | Inactive | 99.67% |
| NPY5R_HUMAN | neuropeptide Y receptor Y5 | -10.04 | -10.11 | -10.09 | 33.17% | CHEMBL492377 | Active | 67.08% |
| OPRD_HUMAN | opioid receptor delta 1 | -9.17 | -8.82 | -9.79 | 37.23% | CHEMBL3609618 | N/A | N/A |
| OPRK_HUMAN | opioid receptor kappa 1 | -12.79 | -9.53 | -10.04 | 34.52% | CHEMBL4100943 | N/A | N/A |
| OPRM_HUMAN | opioid receptor mu 1 | -10.94 | -8.72 | -9.78 | 37.66% | CHEMBL228687 | Inactive | 54.33% |
| OPRX_HUMAN | opioid related nociceptin receptor 1 | -9.71 | -9.84 | -8.93 | 38.69% | CHEMBL1783823 | N/A | N/A |
| PTAFR_HUMAN | platelet activating factor receptor | -10.56 | -10.30 | -10.71 | 36.84% | CHEMBL37358 | Active | 62.78% |
| TAAR1_HUMAN | trace amine associated receptor 1 | -10.57 | -11.20 | -11.75 | 37.96% | CHEMBL1446878 | Inactive | 71.48% |
| TSHR_HUMAN | thyroid stimulating hormone receptor | -10.04 | -12.02 | -10.44 | 26.94% | CHEMBL1708839 | Inactive | 67.09% |
| V1AR_HUMAN | arginine vasopressin receptor 1A | -9.91 | -9.17 | -10.74 | 34.58% | CHEMBL1837024 | Inactive | 73.63% |
| VIPR1_HUMAN | vasoactive intestinal peptide receptor 1 | -9.08 | -10.39 | -10.38 | 23.18% | CHEMBL520349 | N/A | N/A |